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by French, Juliet D and Ghoussaini, Maya and Edwards, Stacey L and Meyer, Kerstin B and Michailidou, Kyriaki and Ahmed, Shahana and Khan, Sofia and Maranian, Mel J and O’Reilly, Martin and Hillman, Kristine M and Betts, Joshua A and Carroll, Thomas and Bailey, Peter J and Dicks, Ed and Beesley, Jonathan and Tyrer, Jonathan and Maia, Ana-Teresa and Beck, Andrew and Knoblauch, Nicholas W and Chen, Shou-Tung and Chen, Constance and Kraft, Peter and Barnes, Daniel and González-Neira, Anna and Alonso, M. Rosario and Herrero, Daniel and Tessier, Daniel C and Vincent, Daniel and Bacot, Francois and Luccarini, Craig and Baynes, Caroline and Conroy, Don and Dennis, Joe and Bolla, Manjeet K and Wang, Xianshu and Wang, Qin and Hopper, John L and Southey, Melissa C and Schmidt, Marjanka K and Broeks, Annegien and Verhoef, Senno and Cornelissen, Sten and Muir, Kenneth and Lophatananon, Artitaya and Stewart-Brown, Sarah and Siriwanarangsan, Pornthep and Fasching, Peter A and Loehberg, Christian R and Ekici, Arif B and Beckmann, Matthias W and Peto, Julian and dos Santos Silva, Isabel and Johnson, Nichola and Aitken, Zoe and Sawyer, Elinor J and Tomlinson, Ian and Kerin, Michael J and Miller, Nicola and Marme, Frederik and Schneeweiss, Andreas and Sohn, Christof and Burwinkel, Barbara and Guénel, Pascal and Truong, Thérèse and Laurent-Puig, Pierre and Menegaux, Florence and Bojesen, Stig E and Nordestgaard, Børge G and Nielsen, Sune F and Flyger, Henrik and Milne, Roger L and Zamora, M. Pilar and Arias Perez, Jose Ignacio and Benitez, Javier and Anton-Culver, Hoda and Brenner, Hermann and Müller, Heiko and Arndt, Volker and Stegmaier, Christa and Meindl, Alfons and Lichtner, Peter and Schmutzler, Rita K and Engel, Christoph and Brauch, Hiltrud and Hamann, Ute and Justenhoven, Christina and Aaltonen, Kirsimari and Heikkilä, Päivi and Aittomäki, Kristiina and Blomqvist, Carl and Matsuo, Keitaro and Ito, Hidemi and Iwata, Hiroji and Sueta, Aiko and Bogdanova, Natalia V and Antonenkova, Natalia N and Dörk, Thilo and Lindblom, Annika and Margolin, Sara and Mannermaa, Arto and ... and KConFab Investigators and GENICA Network and kConFab Investigators
The American Journal of Human Genetics, ISSN 0002-9297, 04/2013, Volume 92, Issue 4, pp. 489 - 503
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2011, Volume 13, Issue 11, pp. 1202 - 1212
Glioma is the most common adult primary brain tumor. Its most malignant form, glioblastoma multiforme (GBM), is almost invariably fatal, due in part to the... 
ELK4 | Mcl-1 | Glioma | Glioblastoma | Apoptosis | SURVIVAL | STEM-CELLS | ACTIVATION | MACROPHAGES | apoptosis | BH3 MIMETIC ABT-737 | INSERTIONS | CLINICAL NEUROLOGY | glioblastoma | ONCOLOGY | glioma | CHRONIC LYMPHOCYTIC-LEUKEMIA | PROMOTER | INHIBITOR | BCL-2 FAMILY | RNA, Small Interfering - genetics | Luciferases - metabolism | ets-Domain Protein Elk-4 - genetics | Humans | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | bcl-X Protein - genetics | Molecular Sequence Data | ets-Domain Protein Elk-4 - metabolism | Promoter Regions, Genetic - genetics | Brain Neoplasms - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Neoplasm Grading | Transfection | Chromatin Immunoprecipitation | Base Sequence | Adult | Glioblastoma - metabolism | Electrophoretic Mobility Shift Assay | Real-Time Polymerase Chain Reaction | Down-Regulation | RNA, Messenger - genetics | Glioblastoma - prevention & control | Mice, SCID | Blotting, Western | Brain Neoplasms - prevention & control | ets-Domain Protein Elk-4 - antagonists & inhibitors | Animals | Glioblastoma - pathology | Myeloid Cell Leukemia Sequence 1 Protein | Cell Line, Tumor | Polymorphism, Single Nucleotide - genetics | Mice, Inbred NOD | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Mice | bcl-X Protein - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Index Medicus | Basic and Translational Investigations
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 32, pp. 13296 - 13311
Sirtuin 7 (SIRT7), a member of theNAD(+)-dependent class III histone deacetylases, is involved in the regulation of various cellular processes and in resisting... 
RNA-POLYMERASE-I | SIRT7-DEPENDENT DEACETYLATION | HEPATOCELLULAR-CARCINOMA | ACTIVATION | TRANSCRIPTION FACTOR FOXO1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-PROLIFERATION | DEPENDENT DEACETYLATION | HAUSP | EXPRESSION | P53 | Glucose-6-Phosphatase - genetics | ets-Domain Protein Elk-4 - genetics | Humans | Substrate Specificity | ets-Domain Protein Elk-4 - metabolism | Recombinant Fusion Proteins - metabolism | Protein Subunits - metabolism | Ubiquitination | RNA Interference | Gene Deletion | HEK293 Cells | Ubiquitin Thiolesterase - metabolism | Lysine - metabolism | Protein Interaction Domains and Motifs | Sirtuins - genetics | Peptide Fragments - genetics | Ubiquitin Thiolesterase - antagonists & inhibitors | Gluconeogenesis | Protein Subunits - genetics | Promoter Regions, Genetic | Peptide Fragments - metabolism | Recombinant Fusion Proteins - chemistry | Ubiquitin Thiolesterase - genetics | Glucose-6-Phosphatase - metabolism | Gene Expression Regulation, Enzymologic | Hydrolysis | Peptide Fragments - antagonists & inhibitors | Glucose-6-Phosphatase - antagonists & inhibitors | Cell Line, Tumor | Protein Processing, Post-Translational | Mutation | Sirtuins - antagonists & inhibitors | Sirtuins - metabolism | Ubiquitin-Specific Peptidase 7 | Amino Acid Substitution | Index Medicus | deubiquitylation (deubiquitination) | post-translational modification | sirtuin | gluconeogenesis | gene expression | Cell Biology
Journal Article
NeuroReport, ISSN 0959-4965, 08/1998, Volume 9, Issue 12, pp. 2703 - 2708
NOCICEPTIN stimulation of the ORL1 receptor expressed in Chinese hamster ovary (CHO) cells results in the activation of the extracellular signal regulated... 
Nociceptin | ORL1 receptor | Reporter gene | Luciferase | Elk-1 | Mitogen-activated protein kinase | Sap1a | ENDOGENOUS LIGAND | CONDUCTANCE | PATHWAYS | nociceptin | ORPHANIN-FQ | PROTEIN-COUPLED RECEPTORS | CASCADES | NEUROSCIENCES | FIBROBLASTS | IN-VITRO | OPIOID RECEPTOR | luciferase | reporter gene | KINASES | Receptors, Opioid - genetics | Up-Regulation | Humans | Receptor Protein-Tyrosine Kinases - physiology | Nociceptors - physiology | Narcotic Antagonists | Transducin - biosynthesis | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Flavonoids - pharmacology | Cyclic AMP - metabolism | CHO Cells | Proto-Oncogene Proteins - antagonists & inhibitors | ets-Domain Protein Elk-4 | Cricetinae | DNA-Binding Proteins - physiology | ets-Domain Protein Elk-1 | DNA-Binding Proteins - antagonists & inhibitors | Calcium-Calmodulin-Dependent Protein Kinases - genetics | Enzyme Inhibitors - pharmacology | Genes, Reporter - genetics | Proto-Oncogene Proteins - genetics | Imidazoles - pharmacology | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | DNA-Binding Proteins - genetics | Animals | Receptor Protein-Tyrosine Kinases - genetics | Proto-Oncogene Proteins - physiology | Receptors, Opioid - biosynthesis | Pyridines - pharmacology | Transcription Factors | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Index Medicus
Journal Article
Journal Article
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