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1. Full Text Abuse potential of 2-(4-iodo-2, 5-dimethoxyphenyl)N-(2-methoxybenzyl)ethanamine (25INBOMe); in vivo and ex vivo approaches
by Jeon, Seo Young and Kim, Young-Hoon and Kim, Sung Jin and Suh, Soo Kyung and Cha, Hye Jin
Neurochemistry International, ISSN 0197-0186, 05/2019, Volume 125, pp. 74 - 81
25I NBOMe (“25-I”, “N-Bomb”), one of new psychoactive substances (NPSs), is being abused for recreational purpose. However, the liability for abuse or... 
PER2 | Self-administration | Synaptosome | 25I[sbnd]NBOMe | Dopamine | Conditioned place preference | Dependence | SGK1 | HPLC | RAT | MORPHINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | 50-KHZ ULTRASONIC VOCALIZATIONS | SEROTONIN SYNTHESIS | SENSITIZATION | GENES | FOOD RESTRICTION | 25I-NBOMe | NEUROBIOLOGY | WITHDRAWAL
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2. Full Text In vivo and ex vivo percutaneous absorption of [14C]-bisphenol A in rats: a possible extrapolation to human absorption?
by Marquet, Fabrice and Payan, Jean-Paul and Beydon, Dominique and Wathier, Ludivine and Grandclaude, Marie-Christine and Ferrari, Elisabeth
Archives of Toxicology, ISSN 0340-5761, 9/2011, Volume 85, Issue 9, pp. 1035 - 1043
Bisphenol A (BPA) is a monomer used mainly in the synthesis of polycarbonates and epoxy resins. Percutaneous absorption is the second source of exposure, after... 
Human | Bisphenol A | Percutaneous absorption | In vivo | Biomedicine | Environmental Health | Rat | Ex vivo | Occupational Medicine/Industrial Medicine | Pharmacology/Toxicology | Biomedicine general | VITRO | PENETRATION | EXCRETION | DISPOSITION | METABOLISM | BISPHENOL-A | TOXICOLOGY | HUMAN URINE | SKIN | RISK-ASSESSMENT | EXPOSURE | Air Pollutants, Occupational - pharmacokinetics | Predictive Value of Tests | Injections, Intravenous | Benzhydryl Compounds | Species Specificity | Skin - metabolism | Humans | Rats | Male | Skin Absorption | Administration, Cutaneous | Chromatography, High Pressure Liquid | Rats, Sprague-Dawley | Phenols - urine | Animals | Diffusion Chambers, Culture | Feces - chemistry | Phenols - pharmacokinetics | Models, Biological | In Vitro Techniques | Air Pollutants, Occupational - urine | Carbon Radioisotopes | Resins | Toxicity | Rodents | Index Medicus | Toxicokinetics and Metabolism
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3. Full Text Tailoring novel soft nano-vesicles ‘Flexosomes’ for enhanced transdermal drug delivery: Optimization, characterization and comprehensive ex vivo – in vivo evaluation
by Abdel-Messih, Hanaa A and Ishak, Rania A.H and Geneidi, Ahmed S and Mansour, Samar
International Journal of Pharmaceutics, ISSN 0378-5173, 04/2019, Volume 560, pp. 101 - 115
The transdermal route is a convenient non-invasive way for drug delivery, however, the hydrophobic compact nature of stratum corneum (SC) forms an obstacle... 
In vivo pharmacokinetics | Edge activator | Nano-vesicles | Micelles | Transdermal delivery | Ex vivo permeation | Ethosomes | Tropisetron hydrochloride (PubChem CID: 656664) | Cholesterol (PubChem CID: 5997) | Cremophor RH 40 (CAS-RN: 61788-85-0) | Phosphatidylcholine (PubChem CID: 24779388) | Sodium deoxycholate (PubChem CID: 23668196) | Cetyl trimethyl ammonium bromide (PubChem CID: 5974) | Sodium cholate (PubChem CID: 23668194) | Ethanol (PubChem CID: 702) | D-α-Tocopherol polyethylene glycol 1000 succinate (TPGS) (PubChem CID: 71406) | Span 85 (PubChem CID: 9920343) | Tween 80 (PubChem CID: 443315) | VITRO | VITAMIN-E | CHITOSAN NANOPARTICLES | FORMULATION | SKIN DELIVERY | PENETRATION ENHANCERS | TROPISETRON | ULTRADEFORMABLE VESICLES | PHARMACOLOGY & PHARMACY | LIPOSOMES | PERMEATION | Chemistry, Pharmaceutical - methods | Skin - metabolism | Antiemetics - administration & dosage | Rats | Biological Availability | Male | Skin Absorption | Administration, Cutaneous | Tropisetron - pharmacokinetics | Drug Delivery Systems | Nanoparticles | Particle Size | Microscopy, Confocal | Antiemetics - pharmacokinetics | Animals | Excipients - chemistry | Ethanol - chemistry | Hydrophobic and Hydrophilic Interactions | Calorimetry, Differential Scanning | Tropisetron - administration & dosage | Phosphates | Transmission electron microscopes | Drugstores | Phospholipids | Permeability | Oral medication | Polyols | Transdermal medication | Surface active agents | Polyethylene glycol | Castor oil | Pharmacy | Tocopherols | Skin | High performance liquid chromatography
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4. Full Text Clinical Ex Vivo Lung Perfusion—Pushing the Limits
by Aigner, C and Slama, A and Hötzenecker, K and Scheed, A and Urbanek, B and Schmid, W and Nierscher, F. J and Lang, G and Klepetko, W
American Journal of Transplantation, ISSN 1600-6135, 07/2012, Volume 12, Issue 7, pp. 1839 - 1847
Ex vivo lung perfusion (EVLP) provides the ability to evaluate donor lungs before transplantation. Yet, limited prospective clinical data exist with regard to... 
marginal donors | lung transplantation | Ex vivo | EVLP | lung perfusion | Marginal donors | Ex vivo lung perfusion | Lung transplantation | UNITED-STATES | SURGERY | EXTENDED DONOR CRITERIA | ALLOCATION | TRANSPLANTATION | Young Adult | Lung Transplantation | Prospective Studies | Perfusion | Humans | Middle Aged | Adolescent | Adult | Female | Male | Aged | In Vitro Techniques | Index Medicus
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5. Full Text Decreased extrusion of calcium phosphate cement versus high viscosity PMMA cement into spongious bone marrow—an ex vivo and in vivo study in sheep vertebrae
by Xin, Long, MD and Bungartz, Matthias, MD and Maenz, Stefan, PhD and Horbert, Victoria, PhD and Hennig, Max, PhD and Illerhaus, Bernhard, MD and Günster, Jens, MD and Bossert, Jörg, PhD and Bischoff, Sabine, MD and Borowski, Juliane and Schubert, Harald, MD and Jandt, Klaus D., PhD and Kunisch, Elke, PhD and Kinne, Raimund W., MD and Brinkmann, Olaf, MD
Spine Journal, The, ISSN 1529-9430, 2016, Volume 16, Issue 12, pp. 1468 - 1477
Abstract Background Context Vertebroplasty or kyphoplasty of osteoporotic vertebral fractures bears the risk of pulmonary cement embolism (3.5%–23%) caused by... 
Orthopedics | In vivo | Ex vivo | Brushite-forming calcium phosphate cement | Bone marrow extrusion | Large animal model | Sheep | Vertebroplasty | Cement injection | High-viscosity PMMA cement | POLYMETHYL METHACRYLATE | POLYMETHYLMETHACRYLATE CEMENT | BIOMECHANICAL EVALUATION | OSTEOPOROTIC COMPRESSION FRACTURES | MECHANICAL-PROPERTIES | PERCUTANEOUS VERTEBROPLASTY | CLINICAL NEUROLOGY | BALLOON KYPHOPLASTY | EXPERIMENTAL-MODEL | PULMONARY-EMBOLISM | ANIMAL-MODEL | ORTHOPEDICS | Viscosity | Bone Cements - adverse effects | Bone Cements - pharmacokinetics | Humans | Lumbar Vertebrae - drug effects | Vertebroplasty - methods | Compressive Strength | Polymethyl Methacrylate - adverse effects | Animals | Pulmonary Embolism - etiology | Calcium Phosphates - pharmacokinetics | Calcium Phosphates - adverse effects | Female | Polymethyl Methacrylate - pharmacokinetics | Bone Cements - chemistry | Bone Marrow - drug effects | Physiological aspects | Osteoporosis | Calcium phosphate | Polymethylmethacrylate | Index Medicus
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6. Full Text Resveratrol improves ex vivo expansion of CB‐CD34+ cells via downregulating intracellular reactive oxygen species level
by Tang, Chaochun and Zhang, Weiwei and Cai, Haibo and Ye, Zhaoyang and Zhang, Xu and Tan, Wensong
Journal of Cellular Biochemistry, ISSN 0730-2312, 05/2019, Volume 120, Issue 5, pp. 7778 - 7787
Intracellular reactive oxygen species (ROS) play important roles in the ex vivo expansion of hematopoietic stem and progenitor cells (HSPCs). In this study,... 
cells | CD34 | ex vivo expansion | resveratrol | reactive oxygen species | MIGRATION | CD34(+) cells | BIOCHEMISTRY & MOLECULAR BIOLOGY | BONE-MARROW | MITOCHONDRIA | ANTIOXIDANT ENZYMES | TENSION | ROS PRODUCTION | SIRT1 | CELL BIOLOGY | HEMATOPOIETIC STEM-CELLS | RECONSTITUTION | Hematopoietic stem cells | Resveratrol | CD34 antigen | Cell culture | Scavenging | Cultures | Progenitor cells | Hemopoiesis | CD90 antigen | CD38 antigen | Cells (biology) | Intracellular | Semisolids | Expansion | Apoptosis
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7. Full Text The protective effect of prone lung position on ischemia–reperfusion injury and lung function in an ex vivo porcine lung model
by Niikawa, Hiromichi and Okamoto, Toshihiro and Ayyat, Kamal S and Itoda, Yoshifumi and Farver, Carol F and McCurry, Kenneth R
The Journal of Thoracic and Cardiovascular Surgery, ISSN 0022-5223, 01/2019, Volume 157, Issue 1, pp. 425 - 433
Prone positioning has been shown to improve oxygenation in patients with lung injury. We hypothesized that prone positioning of lungs during ex vivo lung... 
ischemia-reperfusion injury | lung transplantation | lung function assessment | ex vivo lung perfusion | prone positioning | SURGERY | PRESSURE | CARDIAC & CARDIOVASCULAR SYSTEMS | RESPIRATORY SYSTEM | PERFUSION | TRANSPLANTATION | Transplantation of organs, tissues, etc | Interleukins | Lung diseases | Reperfusion injury
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8. Full Text Hemofiltration in ex vivo lung perfusion—a study in experimentally induced pulmonary edema
by Nilsson, Tobias, MD and Hansson, Christoffer, MS and Wallinder, Andreas, MD, PhD and Malm, Carl-Johan, MD and Silverborn, Martin, MD, PhD and Ricksten, Sven-Erik, MD, PhD and Dellgren, Göran, MD, PhD and Institute of Medicine and Institute of Medicine, Department of Molecular and Clinical Medicine and Göteborgs universitet and Institutionen för kliniska vetenskaper, sektionen för anestesi, biomaterial och ortopedi. Avdelningen för anestesiologi och intensivvård and Gothenburg University and Sahlgrenska Academy and Institute of Clinical Sciences, Section for Anesthesiology, Biomaterials and Orthopaedics. Department of Anesthesiology and Intensive care and Sahlgrenska akademin and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Institutionen för medicin
Journal of Thoracic and Cardiovascular Surgery, The, ISSN 0022-5223, 2016, Volume 151, Issue 2, pp. 570 - 575.e1
Abstract Objectives Ex vivo lung perfusion (EVLP) can potentially reduce pulmonary edema. In a pig model with induced pulmonary edema, we evaluated the effect... 
Cardiothoracic Surgery | hemofiltration | lung edema | ex vivo lung perfusion | lung reconditioning | Lung reconditioning | Lung edema | Hemofiltration | Ex vivo lung perfusion | SURGERY | IMPROVE | CARDIAC & CARDIOVASCULAR SYSTEMS | RESPIRATORY SYSTEM | REJECTED DONOR LUNGS | EXPERIENCE | TRANSPLANTATION | Lung - pathology | Vasodilator Agents - pharmacology | Lung Compliance | Organ Size | Lung - physiopathology | Nitroglycerin - pharmacology | Pressure | Feasibility Studies | Pulmonary Circulation | Perfusion - methods | Pulmonary Edema - physiopathology | Pulmonary Edema - therapy | Animals | Time Factors | Swine | Lung - drug effects | Models, Animal | Pulmonary Edema - pathology | In Vitro Techniques | Lung - blood supply | Respiration | Anesthesia | Pulmonary edema | Analysis | Index Medicus | Abridged Index Medicus | Klinisk medicin | Clinical Medicine | ex vivo lung perfusion; lung edema; lung reconditioning; hemofiltration
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9. Full Text Autophagic flux determination in vivo and ex vivo
by Esteban-Martínez, Lorena and Boya, Patricia
Methods, ISSN 1046-2023, 03/2015, Volume 75, pp. 79 - 86
Autophagy is a highly dynamic process that mediates the degradation of cellular constituents inside lysosomes. It is characterized by the formation of... 
Cerebellum | Ex vivo autophagy determination | Liver | In vivo autophagy determination | Autophagic flux | Retina | GFP-LC3 mice | NERVOUS-SYSTEM | CELLS | APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MACHINERY | BIOCHEMICAL RESEARCH METHODS | NEURODEGENERATION | DEATH | MACROAUTOPHAGY | DEGENERATION | BASAL AUTOPHAGY | MICE | Retina - metabolism | Liver - ultrastructure | Cerebellum - metabolism | Liver - metabolism | Lysosomes - genetics | Leupeptins - chemistry | Lysosomes - ultrastructure | Animals | Lysosomes - metabolism | Microscopy, Fluorescence - methods | Retina - ultrastructure | Mice | Autophagy - genetics | Cerebellum - ultrastructure | Index Medicus
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10. Full Text Ischemic small intestine - In vivo versus ex vivo bioimpedance measurements
by Strand-Amundsen, Runar J and Reims, Henrik M and Tronstad, Christian and Kalvøy, Håvard and Martinsen, Orjan G and Høgetveit, Jan O and Ruud, Tom E and Tønnessen, Tor I
Physiological Measurement, ISSN 0967-3334, 04/2017, Volume 38, Issue 5, pp. 715 - 728
Objective: Bioimpedance has been used to investigate changes in electrical parameters during ischemia in various tissues. The small intestine is a multilayered... 
bioimpedance | in vivo | small intestine | ex vivo | ischemia | PHYSIOLOGY | ENGINEERING, BIOMEDICAL | FREQUENCY-RANGE | VIABILITY | ELECTRICAL-IMPEDANCE | INJURY | MUSCLE | MESENTERIC ISCHEMIA | POSTMORTEM | BIOPHYSICS | SPECTROSCOPY | DIELECTRIC-PROPERTIES | BIOLOGICAL TISSUES | Electrodes | Animals | Female | Male | Electric Impedance | Intestine, Small - blood supply | Sus scrofa | Ischemia - pathology | Index Medicus
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11. Full Text Ex Vivo Lung Perfusion
by Tane, Shinya and Noda, Kentaro and Shigemura, Norihisa
Chest, ISSN 0012-3692, 06/2017, Volume 151, Issue 6, pp. 1220 - 1228
Ex vivo lung perfusion (EVLP) promises to be a comprehensive platform for assessment, reconditioning, and preservation of donor lungs and has been dramatically... 
lung | translational research | ex vivo lung perfusion | oncology | bioengineering
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12. Full Text A system using patient‐specific 3D‐printed molds to spatially align in vivo MRI with ex vivo MRI and whole‐mount histopathology for prostate cancer research
by Wu, Holden H and Priester, Alan and Khoshnoodi, Pooria and Zhang, Zhaohuan and Shakeri, Sepideh and Afshari Mirak, Sohrab and Asvadi, Nazanin H and Ahuja, Preeti and Sung, Kyunghyun and Natarajan, Shyam and Sisk, Anthony and Reiter, Robert and Raman, Steven and Enzmann, Dieter
Journal of Magnetic Resonance Imaging, ISSN 1053-1807, 01/2019, Volume 49, Issue 1, pp. 270 - 279
Background Patient-specific 3D-printed molds and ex vivo MRI of the resected prostate have been two important strategies to align MRI with whole-mount... 
prostate MRI | ex vivo MRI | 3D‐printed molds | MRI‐pathology correlation | MRI-pathology correlation | 3D-printed molds | VOLUME | VALIDATION | HISTOLOGY | IMAGES | DIFFUSION | REGISTRATION | CORRELATE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | MULTIPARAMETRIC MRI | Medical research | Molds | Workflow | Population studies | Laparoscopy | Rank tests | Field strength | Alignment | Histopathology | Three dimensional printing | Magnetic resonance imaging | Echo surveys | Registration | In vivo methods and tests | Prostate cancer | Prostate
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13. Full Text First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127− T regulatory cells
by Trzonkowski, Piotr and Bieniaszewska, Maria and Juścińska, Jolanta and Dobyszuk, Anita and Krzystyniak, Adam and Marek, Natalia and Myśliwska, Jolanta and Hellmann, Andrzej
Clinical Immunology, ISSN 1521-6616, 2009, Volume 133, Issue 1, pp. 22 - 26
Abstract Here, we describe a procedure and first-in-man clinical effects of adoptive transfer of ex vivo expanded CD4+CD25+CD127− T regulatory cells (Tregs) in... 
Allergy and Immunology | Human | Ex vivo expansion | Graft versus host disease | Immunotherapy | Adoptive transfer | CD4+CD25+ T regulatory cells | CD4+CD25+T regulatory cells | TRIALS | ACUTE GVHD | TOLERANCE | IMMUNOLOGY | FOXP3 | ACTIVATED T-CELLS | EXPANSION | EXPRESSION | Graft vs Host Disease - therapy | CD4 Antigens - immunology | Acute Disease | Humans | Immunosuppressive Agents - therapeutic use | Leukemia, Myeloid - immunology | Male | Interleukin-7 Receptor alpha Subunit - immunology | Adoptive Transfer | Graft vs Host Disease - immunology | T-Lymphocytes, Regulatory - immunology | Bone Marrow Transplantation - immunology | Leukemia, Myeloid - drug therapy | Bone Marrow Transplantation - adverse effects | Adult | Female | T-Lymphocytes, Regulatory - transplantation | Chronic Disease | Myelodysplastic Syndromes - drug therapy | Myelodysplastic Syndromes - immunology | Interleukin-2 Receptor alpha Subunit - immunology | Stem Cell Transplantation - adverse effects | Graft versus host reaction | Care and treatment | Universities and colleges | Blood banks | Immunosuppressive agents | Index Medicus
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14. Full Text Ex vivo and in vivo evaluation of residual chlorhexidine gluconate on skin following repetitive exposure to saline and wiping with 2% chlorhexidine gluconate/70% isopropyl alcohol pre-operative skin preparations
by Bashir, M.H and Hollingsworth, A and Schwab, D and Prinsen, K.S and Paulson, J.E and Morse, D.J and Bernatchez, S.F
Journal of Hospital Infection, ISSN 0195-6701, 07/2019, Volume 102, Issue 3, pp. 256 - 261
Skin antisepsis is performed before surgery to minimize the risk of surgical site infections. Chlorhexidine gluconate (CHG) is routinely used in this... 
Ex vivo | Surgical site infection | Chlorhexidine gluconate | Film-forming copolymer | In vivo | Skin antisepsis | In vivo | Ex vivo | ADHESION | INFECTIOUS DISEASES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | POVIDONE-IODINE | Skin | Swine | Health aspects | High performance liquid chromatography | Alcohols
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