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Cell Death and Differentiation, ISSN 1350-9047, 03/2017, Volume 24, Issue 3, pp. 481 - 491
Peptido-mimetic inhibitor of apoptosis protein (IAP) antagonists (Smac mimetics (SMs)) can kill tumour cells by depleting endogenous IAPs and thereby inducing... 
TUMOR-NECROSIS-FACTOR | INTERFERON-GAMMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | ALPHA-DEPENDENT APOPTOSIS | RECEPTOR | FAS-MEDIATED APOPTOSIS | TNF-ALPHA | NF-KAPPA-B | SIGNALING COMPLEXES | EXPRESSION | CELL BIOLOGY | Protein Kinases - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Caspase Inhibitors - pharmacology | Apoptosis - drug effects | Humans | Caspase 8 - metabolism | Caspase 8 - chemistry | Cytokine TWEAK - pharmacology | Interferon-gamma - metabolism | Receptors, Tumor Necrosis Factor, Type I - metabolism | Recombinant Proteins - biosynthesis | Caspase 8 - genetics | Recombinant Proteins - isolation & purification | Receptors, Tumor Necrosis Factor, Type I - deficiency | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Pentanoic Acids - pharmacology | Inhibitor of Apoptosis Proteins - metabolism | Protein Kinases - deficiency | Interferon-gamma - genetics | Cell Line | Caspase 10 - metabolism | Recombinant Proteins - pharmacology | Receptors, Tumor Necrosis Factor, Type I - genetics | CRISPR-Cas Systems - genetics | Mice, Knockout | Drug Synergism | HT29 Cells | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Caspase 10 - genetics | Caspase 10 - chemistry | Mice | Receptor-Interacting Protein Serine-Threonine Kinases - deficiency | Interferon-gamma - pharmacology | Original Paper
Journal Article
Nature Reviews Rheumatology, ISSN 1759-4790, 04/2017, Volume 13, Issue 4, pp. 217 - 233
TNF blockers are highly efficacious at dampening inflammation and reducing symptoms in rheumatic diseases such as rheumatoid arthritis, psoriatic arthritis and... 
LIGAND 1A TL1A | COLLAGEN-INDUCED ARTHRITIS | FIBROBLAST-LIKE SYNOVIOCYTES | TUMOR-NECROSIS-FACTOR | SYSTEMIC-LUPUS-ERYTHEMATOSUS | LYMPHOTOXIN-BETA-RECEPTOR | SYNOVIAL FIBROBLASTS | CD4(+) T-CELLS | CD40 LIGAND | MONOCLONAL-ANTIBODY | RHEUMATOLOGY | Fas Ligand Protein - metabolism | Rheumatic Diseases - drug therapy | OX40 Ligand - metabolism | CD27 Ligand - antagonists & inhibitors | Dendritic Cells - immunology | Humans | Lymphotoxin-alpha - metabolism | Molecular Targeted Therapy | 4-1BB Ligand - antagonists & inhibitors | TNF-Related Apoptosis-Inducing Ligand - antagonists & inhibitors | CD40 Ligand - metabolism | CD27 Ligand - metabolism | Cell Death | Rheumatic Diseases - immunology | Signal Transduction | Lymphocyte Activation | Tumor Necrosis Factors - metabolism | 4-1BB Ligand - metabolism | Immune Tolerance | Tumor Necrosis Factor Ligand Superfamily Member 15 - metabolism | TNF-Related Apoptosis-Inducing Ligand - metabolism | Tumor Necrosis Factor Ligand Superfamily Member 14 - metabolism | Tumor Necrosis Factors - immunology | OX40 Ligand - antagonists & inhibitors | Cytokine TWEAK | Fas Ligand Protein - antagonists & inhibitors | Animals | Tumor Necrosis Factor Ligand Superfamily Member 15 - antagonists & inhibitors | T-Lymphocytes - immunology | Tumor Necrosis Factor Ligand Superfamily Member 14 - antagonists & inhibitors | CD40 Ligand - antagonists & inhibitors | Lymphotoxin-alpha - antagonists & inhibitors | Tumor Necrosis Factors - antagonists & inhibitors | Care and treatment | Cytokines | Tumor necrosis factor | Rheumatic diseases | Development and progression | Genetic aspects | Health aspects
Journal Article
Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7339, pp. 523 - 526
Journal Article
Nature Medicine, ISSN 1078-8956, 2014, Volume 20, Issue 4, pp. 398 - 407
Journal Article
Journal Article
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