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Biotechnology and Bioengineering, ISSN 0006-3592, 10/2015, Volume 112, Issue 10, pp. 2172 - 2184
Journal Article
Biotechnology and Bioengineering, ISSN 0006-3592, 07/2017, Volume 114, Issue 7, pp. 1448 - 1458
Journal Article
Journal Article
Biotechnology and Bioengineering, ISSN 0006-3592, 09/2018, Volume 115, Issue 9, pp. 2315 - 2327
Lactate is one of the key waste metabolites of mammalian cell culture. High lactate levels are caused by high aerobic glycolysis, also known as the Warburg... 
fed batch | lactate | monoclonal antibody | pyruvate dehydrogenase kinase | Chinese hamster ovary cells | Warburg effect | LACTATE-DEHYDROGENASE | ALLOSTERIC REGULATION | FED-BATCH | DICHLOROACETATE | MAMMALIAN-CELLS | PYRUVATE-DEHYDROGENASE | FLUX ANALYSIS | SKELETAL-MUSCLE 6-PHOSPHOFRUCTO-1-KINASE | METABOLISM | HAMSTER OVARY CELLS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | Pyruvate Dehydrogenase Complex - metabolism | Pyruvates - metabolism | Recombinant Proteins - metabolism | Aerobiosis | Antibodies - metabolism | Cricetulus | Cell Survival | Technology, Pharmaceutical - methods | Recombinant Proteins - genetics | Metabolic Flux Analysis | Cell Culture Techniques - methods | Acetyl Coenzyme A - metabolism | Animals | Lactates - metabolism | Bioreactors | Biological Products - metabolism | Glycolysis | Antibodies - genetics | Culture Media - chemistry | CHO Cells | Lactates | Glucose metabolism | Enzymes | Production management | Analysis | Monoclonal antibodies | Cells | Tricarboxylic acid cycle | Cell culture | Dichloroacetic acid | Media (culture) | Dehydrogenases | Pyruvic acid | Glucose | Kinases | Dehydrogenase | Cell density | Proteins | Metabolic flux | Metabolites | Fed batch | Coenzyme A | Productivity | Pyruvate dehydrogenase (lipoamide) | Cultures | Glycosylation | Fluxes | Sodium chloride | Feeding | Sodium lactate | Sodium | Proteomics | Lactic acid | Index Medicus
Journal Article
Journal Article
Biotechnology and Bioengineering, ISSN 0006-3592, 03/2015, Volume 112, Issue 3, pp. 521 - 535
Journal Article
Biotechnology and Bioengineering, ISSN 0006-3592, 02/2019, Volume 116, Issue 2, pp. 320 - 332
Journal Article