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1. Full Text Does First-Trimester Screening Modify the Natural History of Congenital Heart Disease?: Analysis of Outcome of Regional Cardiac Screening at 2 Different Time Periods
by Jicinska, Hana and Vlasin, Pavel and Jicinsky, Michal and Grochova, Ilga and Tomek, Viktor and Volaufova, Julia and Skovranek, Jan and Marek, Jan
Circulation, ISSN 0009-7322, 03/2017, Volume 135, Issue 11, pp. 1045 - 1055
BACKGROUND:The study analyzed the impact of first-trimester screening on the spectrum of congenital heart defects (CHDs) later in pregnancy and on the outcome... 
first-trimester screening | epidemiology | prenatal cardiology | echocardiography | congenital heart defects | DIAGNOSIS | DEFECTS | CARDIAC & CARDIOVASCULAR SYSTEMS | ABNORMALITIES | CHROMOSOMAL-ANOMALIES | AORTIC-STENOSIS | MALFORMATIONS | PERIPHERAL VASCULAR DISEASE | 1ST TRIMESTER | FETAL | NUCHAL TRANSLUCENCY | Pregnancy Trimester, Second | Fetus - diagnostic imaging | Echocardiography | Comorbidity | Humans | Pregnancy Trimester, First | Pregnancy | Heart Defects, Congenital - genetics | Czech Republic | Ultrasonography, Prenatal | Chromosome Aberrations | Heart Defects, Congenital - epidemiology | Female | Heart Defects, Congenital - diagnosis | Retrospective Studies | Medical examination | Pregnant women | Analysis | Outcome and process assessment (Health Care) | Fetus | Congenital heart disease | Diagnosis | Health aspects
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2. Full Text Systematic review of first‐trimester ultrasound screening for detection of fetal structural anomalies and factors that affect screening performance
by Karim, J. N and Roberts, N. W and Salomon, L. J and Papageorghiou, A. T
Ultrasound in Obstetrics & Gynecology, ISSN 0960-7692, 10/2017, Volume 50, Issue 4, pp. 429 - 441
This article's abstract has been translated into Spanish and Chinese. Follow the links from the abstract to view the translations. Linked Comment: Ultrasound... 
fetal anomalies | congenital abnormalities | first trimester | prenatal diagnosis | prenatal screening | ultrasound | UNSELECTED POPULATION | EXAMINATION PROTOCOL | NUCHAL TRANSLUCENCY THICKNESS | RANDOMIZED CONTROLLED-TRIAL | DIAGNOSTIC-ACCURACY | OBSTETRICS & GYNECOLOGY | TRANSVAGINAL SONOGRAPHY | ACOUSTICS | EARLY-PREGNANCY | CHROMOSOMALLY NORMAL FETUSES | TURNER SYNDROME | 1ST TRIMESTER | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Pregnancy | Reference Standards | Reproducibility of Results | Ultrasonography, Prenatal | Humans | Sensitivity and Specificity | Clinical Protocols | Female | Congenital Abnormalities - diagnostic imaging | Pregnancy Trimester, First | Pregnant women | Analysis | Genetic disorders | Health care | Populations | Statistical analysis | Risk groups | Population characteristics | Fetuses | Abnormalities | Data processing | Population studies | Risk | Gestation | Medical screening | Subgroups | Gestational age | Studies | Screening | Sensitivity | Ultrasonic imaging | Diagnostic systems | Ultrasound | Translations | Anomalies
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3. Full Text Risk of fetal loss associated with invasive testing following combined first‐trimester screening for Down syndrome: a national cohort of 147 987 singleton pregnancies
by Wulff, C. B and Gerds, T. A and Rode, L and Ekelund, C. K and Petersen, O. B and Tabor, A and Zingenberg, H and Jørgensen, F. S and Sundberg, K and Shalmi, A. ‐C and Näslund Thagaard, I and Skibsted, L and Fabricius, M and Sperling, L and Mogensen, H and Ibsen, M and Brendstrup, L and Petersen, O. B and Jensen, H. S and Kamper, C. H and Vase, L and Østergaard, M and Sørensen, A and Størup, B and Danish Fetal Med Study Grp and Danish Fetal Medicine Study Group
Ultrasound in Obstetrics & Gynecology, ISSN 0960-7692, 01/2016, Volume 47, Issue 1, pp. 38 - 44
Linked Comment: Ultrasound Obstet Gynecol 2016; 47: 14–14 
amniocentesis | procedure‐related risk | chorionic villus sampling | invasive prenatal testing | miscarriage | stillbirth | combined first‐trimester screening | fetal loss | procedure-related risk | combined first-trimester screening | PROPENSITY SCORE | MEDICINE | TRISOMY-21 | PREDICTION | OBSTETRICS & GYNECOLOGY | ACOUSTICS | ULTRASOUND | GESTATION | 1ST TRIMESTER | NUCHAL TRANSLUCENCY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Humans | Risk | Pregnancy Trimester, First | Case-Control Studies | Amniocentesis - statistics & numerical data | Pregnancy | Young Adult | Propensity Score | Abortion, Spontaneous - epidemiology | Chorionic Gonadotropin, beta Subunit, Human - metabolism | Chorionic Villi Sampling - statistics & numerical data | Ultrasonography, Prenatal | Nuchal Translucency Measurement | Stillbirth - epidemiology | Denmark - epidemiology | Adult | Female | Retrospective Studies | Down Syndrome - diagnosis | Pregnancy-Associated Plasma Protein-A - metabolism | Cohort Studies
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4. Full Text Accuracy of competing‐risks model in screening for pre‐eclampsia by maternal factors and biomarkers at 11–13 weeks' gestation
by O'Gorman, N and Wright, D and Poon, L. C and Rolnik, D. L and Syngelaki, A and Wright, A and Akolekar, R and Cicero, S and Janga, D and Jani, J and Molina, F. S and de Paco Matallana, C and Papantoniou, N and Persico, N and Plasencia, W and Singh, M and Nicolaides, K. H
Ultrasound in Obstetrics & Gynecology, ISSN 0960-7692, 06/2017, Volume 49, Issue 6, pp. 751 - 755
Objective To examine the diagnostic accuracy of a previously developed model for prediction of pre-eclampsia (PE) by a combination of maternal factors and... 
placental growth factor | pyramid of pregnancy care | survival model | uterine artery Doppler | mean arterial pressure | Bayes' theorem | pre‐eclampsia | pregnancy‐associated plasma protein‐A | first‐trimester screening | first-trimester screening | pre-eclampsia | pregnancy-associated plasma protein-A | 3 TRIMESTERS | OBSTETRICS & GYNECOLOGY | ACOUSTICS | MEDICAL HISTORY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | MEAN ARTERIAL-PRESSURE | Models, Theoretical | Prospective Studies | Pulsatile Flow | Risk Assessment | Europe | Humans | Prenatal Diagnosis | Placenta Growth Factor - blood | Biomarkers - blood | Gestational Age | Pregnancy Trimester, First | Uterine Artery - physiology | Pregnancy | Pre-Eclampsia - blood | Sensitivity and Specificity | Adult | Female | Pre-Eclampsia - diagnosis | Algorithms | Risk assessment | Preeclampsia | Models | Biological markers | Blood proteins | Population studies | Pre-eclampsia | Gestation | Medical screening | Risk factors | Screening | Accuracy | Placenta | Uterus | Copyrights | Eclampsia | Biomarkers | Bioindicators | Blood pressure | Mathematical models | Diagnostic systems | Health risk assessment
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5. Full Text Screening for pre‐eclampsia by maternal factors and biomarkers at 11–13 weeks' gestation
by Tan, M. Y and Syngelaki, A and Poon, L. C and Rolnik, D. L and O'Gorman, N and Delgado, J. L and Akolekar, R and Konstantinidou, L and Tsavdaridou, M and Galeva, S and Ajdacka, U and Molina, F. S and Persico, N and Jani, J. C and Plasencia, W and Greco, E and Papaioannou, G and Wright, A and Wright, D and Nicolaides, K. H
Ultrasound in Obstetrics & Gynecology, ISSN 0960-7692, 08/2018, Volume 52, Issue 2, pp. 186 - 195
Objective To examine the performance of screening for early, preterm and term pre-eclampsia (PE) at 11-13weeks' gestation by maternal factors and combinations... 
placental growth factor | pyramid of pregnancy care | survival model | uterine artery Doppler | SPREE | mean arterial pressure | Bayes' theorem | aspirin | ASPRE | pregnancy‐associated plasma protein‐A | first‐trimester screening | first-trimester screening | pregnancy-associated plasma protein-A | 3 TRIMESTERS | PREGNANCY | PREDICTION | OBSTETRICS & GYNECOLOGY | ACOUSTICS | HYPERTENSION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | MEAN ARTERIAL-PRESSURE
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6. Full Text Multicenter screening for pre‐eclampsia by maternal factors and biomarkers at 11–13 weeks' gestation: comparison with NICE guidelines and ACOG recommendations
by O'Gorman, N and Wright, D and Poon, L. C and Rolnik, D. L and Syngelaki, A and de Alvarado, M and Carbone, I. F and Dutemeyer, V and Fiolna, M and Frick, A and Karagiotis, N and Mastrodima, S and de Paco Matallana, C and Papaioannou, G and Pazos, A and Plasencia, W and Nicolaides, K. H
Ultrasound in Obstetrics & Gynecology, ISSN 0960-7692, 06/2017, Volume 49, Issue 6, pp. 756 - 760
This article's abstract has been translated into Spanish and Chinese. Follow the links from the abstract to view the translations. This article has been... 
placental growth factor | pyramid of pregnancy care | survival model | uterine artery Doppler | mean arterial pressure | Bayes' theorem | pre‐eclampsia | pregnancy‐associated plasma protein‐A | first‐trimester screening | first-trimester screening | pre-eclampsia | pregnancy-associated plasma protein-A | 3 TRIMESTERS | PREVENTION | PREGNANCY | OBSTETRICS & GYNECOLOGY | ACOUSTICS | LOW-DOSE ASPIRIN | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | MEAN ARTERIAL-PRESSURE | Prospective Studies | Risk Assessment | United States | Humans | Prenatal Diagnosis | United Kingdom | Biomarkers - blood | Gestational Age | Pregnancy Trimester, First | Pregnancy | Societies, Medical | Pre-Eclampsia - blood | Female | ROC Curve | Practice Guidelines as Topic | Pre-Eclampsia - diagnosis | Aspirin | Usage | Algorithms | Analysis | Preeclampsia | Medical screening | Blood proteins | Population studies | Biochemistry | Gestation | Risk factors | Guidelines | Uterus | Copyrights | Eclampsia | Measurement methods | Bioindicators | Blood pressure | Mathematical models | Risk groups | Fetuses | Media | Pre-eclampsia | Risk analysis | Medicine | Screening | Placenta | Biomarkers | Links | Health risk assessment | Bayesian analysis | Translations
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7. Full Text Screening for trisomies 21, 18 and 13 by cell‐free DNA analysis of maternal blood at 10–11 weeks' gestation and the combined test at 11–13 weeks
by Quezada, M. S and Gil, M. M and Francisco, C and Oròsz, G and Nicolaides, K. H
Ultrasound in Obstetrics & Gynecology, ISSN 0960-7692, 01/2015, Volume 45, Issue 1, pp. 36 - 41
This article has been selected for Journal Club. Click here to view slides and discussion points. 
cell‐free | screening | trisomies | first trimester | DNA | combined test | prenatal diagnosis | fetal fraction | Screening | Prenatal diagnosis | Trisomies | Fetal fraction | Cell-free DNA | Combined test | First trimester | ACOUSTICS | FETAL ANEUPLOIDIES | cell-free DNA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | OBSTETRICS & GYNECOLOGY | Chromosomes, Human, Pair 18 - metabolism | Decision Making | Chromosomes, Human, Pair 21 - metabolism | Humans | Prenatal Diagnosis | Chromosomes, Human, Pair 13 - metabolism | Maternal Serum Screening Tests | Genetic Counseling | Pregnancy Trimester, First | Pregnancy | Trisomy - diagnosis | Cell-Free System | Sensitivity and Specificity | Adult | Female | Pregnant women | Chromosomes | Analysis | Miscarriage | Premature birth | Deoxyribonucleic acid--DNA
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8. Full Text ASPRE trial: performance of screening for preterm pre‐eclampsia
by Rolnik, D. L and Wright, D and Poon, L. C. Y and Syngelaki, A and O'Gorman, N and de Paco Matallana, C and Akolekar, R and Cicero, S and Janga, D and Singh, M and Molina, F. S and Persico, N and Jani, J. C and Plasencia, W and Papaioannou, G and Tenenbaum‐Gavish, K and Nicolaides, K. H
Ultrasound in Obstetrics & Gynecology, ISSN 0960-7692, 10/2017, Volume 50, Issue 4, pp. 492 - 495
This article's abstract has been translated into Spanish and Chinese. Follow the links from the abstract to view the translations. This article has been... 
placental growth factor | pyramid of pregnancy care | uterine artery Doppler | ASPRE trial | mean arterial pressure | pre‐eclampsia | pregnancy‐associated plasma protein‐A | first‐trimester screening | first-trimester screening | pre-eclampsia | pregnancy-associated plasma protein-A | 3 TRIMESTERS | HYPERTENSION-IN-PREGNANCY | OBSTETRICS & GYNECOLOGY | ACOUSTICS | MATERNAL CHARACTERISTICS | 11-13 WEEKS GESTATION | MEDICAL HISTORY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | MEAN ARTERIAL-PRESSURE | Pregnancy | Aspirin | Algorithms | Pregnant women | Preeclampsia | Blood proteins | Population studies | Pre-eclampsia | Gestation | Medical screening | Abortion | Screening | Placenta | Uterus | Eclampsia | Blood pressure | Miscarriage | Translations
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9. Full Text Protocol for the prospective validation study: ‘Screening programme for pre‐eclampsia’ (SPREE)
by Tan, M. Y and Koutoulas, L and Wright, D and Nicolaides, K. H and Poon, L. C. Y
Ultrasound in Obstetrics & Gynecology, ISSN 0960-7692, 08/2017, Volume 50, Issue 2, pp. 175 - 179
Pre‐eclampsia ( PE ), which affects about 2% of pregnancies, is a major cause of maternal and perinatal morbidity and mortality. Early detection of PE can... 
placental growth factor | National Institute for Health and Care Excellence | uterine artery Doppler | mean arterial pressure | Bayes' theorem | pre‐eclampsia | pregnancy‐associated plasma protein‐A | first‐trimester screening | first-trimester screening | pre-eclampsia | pregnancy-associated plasma protein-A | MORTALITY | HYPERTENSIVE DISORDERS | PREGNANCY | PREDICTION | OBSTETRICS & GYNECOLOGY | ACOUSTICS | IMPACT | WEEKS GESTATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Pregnancy | Prospective Studies | State Medicine | Validation Studies as Topic | Humans | Prenatal Diagnosis | Female | United Kingdom | Pregnancy Trimester, First | Research Design | Pre-Eclampsia - diagnosis | Aspirin | Pregnant women | Analysis | Mortality | Preeclampsia | Health aspects | Blood proteins | Intervention | Theorems | Demography | Pre-eclampsia | Gestation | Medical screening | Morbidity | Risk factors | Screening | Demographics | Placenta | Uterus | Eclampsia | Blood pressure | Health risk assessment | Bayesian analysis
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10. Full Text Screening for fetal aneuploidies at 11 to 13 weeks
by Nicolaides, Kypros H
Prenatal Diagnosis, ISSN 0197-3851, 01/2011, Volume 31, Issue 1, pp. 7 - 15
Effective screening for major aneuploidies can be provided in the first trimester of pregnancy. Screening by a combination of fetal nuchal translucency and... 
serum free β‐hCG | serum PAPP‐A | nuchal translucency | aneuploidies | trisomy 21 | first‐trimester screening | Trisomy 21 | Nuchal translucency | First-trimester screening | Serum free β-hCG | Aneuploidies | Serum PAPP-A | TWIN TRANSFUSION SYNDROME | first-trimester screening | serum PAPP-A | HUMAN CHORIONIC-GONADOTROPIN | PLASMA-PROTEIN-A | OBSTETRICS & GYNECOLOGY | NUCHAL-TRANSLUCENCY THICKNESS | MATERNAL SERUM BIOCHEMISTRY | FREE BETA-HCG | PATIENT-SPECIFIC RISKS | GENETICS & HEREDITY | CHROMOSOMALLY ABNORMAL FETUSES | 1ST TRIMESTER | DOWN-SYNDROME PREGNANCIES | serum free beta-hCG | Pregnancy-Associated Plasma Protein-A - analysis | Humans | Chorionic Gonadotropin, beta Subunit, Human - blood | Aneuploidy | False Positive Reactions | Gestational Age | Pregnancy | Ultrasonography, Prenatal | Nuchal Translucency Measurement | Female | Down Syndrome - diagnosis | Prenatal Diagnosis - methods | Twins | Trisomy | Prenatal diagnosis | tricuspid valve | Fetuses | Pituitary (anterior) | Bone | hepatic artery | Ultrasound
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11. Full Text Population-based impact of noninvasive prenatal screening on screening and diagnostic testing for fetal aneuploidy
by Hui, Lisa and Hutchinson, Briohny and Poulton, Alice and Halliday, Jane
Genetics in medicine : official journal of the American College of Medical Genetics, ISSN 1098-3600, 12/2017, Volume 19, Issue 12, pp. 1338 - 1345
Purpose: To assess the population-wide impact of noninvasive prenatal screening (NIPS) on combined first-trimester screening (CFTS), early ultrasound (11-13... 
noninvasive prenatal screening | ULTRASOUND | MICROARRAY | GENETICS & HEREDITY | NIPS | 1ST TRIMESTER | NIPT | prenatal diagnosis | combined first-trimester screening | CELL-FREE DNA | Births | Prenatal development | Ultrasonic imaging
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12. Full Text Two-stage screening for preterm preeclampsia at 11–13 weeks’ gestation
by Wright, David and Wright, Alan and Syngelaki, Argyro and Georgantis, Apostolos and Nicolaides, Kypros H
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 02/2019, Volume 220, Issue 2, pp. 197.e1 - 197.e11
Screening for preeclampsia at 11–13 weeks’ gestation by a combination of maternal factors, mean arterial pressure, uterine artery pulsatility index, and serum... 
placental growth factor | contingent screening | survival model | uterine artery Doppler | mean arterial pressure | first-trimester screening | aspirin | preeclampsia | Bayes theorem | HYPERTENSIVE DISORDERS | BIOCHEMICAL MARKERS | PREVENTION | RISK | TRISOMY-21 | PREDICTION | OBSTETRICS & GYNECOLOGY | PREGNANCIES | DOWN-SYNDROME
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