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PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e21225
Background: The safety and immunogenicity of a vaccine regimen consisting of a 6-plasmid HIV-1 DNA prime (envA, envB, envC, gagB, polB, nefB) boosted by a... 
RESPONSES | IMMUNITY | ASSAY | SAFETY | MULTIDISCIPLINARY SCIENCES | ANTIBODY | IMMUNOGENICITY EVALUATION | CANDIDATE | INFECTION | STEP | MEMORY T-CELLS | env Gene Products, Human Immunodeficiency Virus - immunology | Immunization, Secondary - adverse effects | Immunoglobulin G - blood | Human Immunodeficiency Virus Proteins - immunology | Humans | Middle Aged | AIDS Vaccines - immunology | Vaccines, DNA - immunology | pol Gene Products, Human Immunodeficiency Virus - immunology | Male | Antibodies, Viral - blood | Vaccines, DNA - administration & dosage | Young Adult | env Gene Products, Human Immunodeficiency Virus - genetics | T-Lymphocytes - metabolism | Immunoglobulin G - immunology | Adenoviridae - genetics | Adult | Female | gag Gene Products, Human Immunodeficiency Virus - genetics | pol Gene Products, Human Immunodeficiency Virus - genetics | Immunization - adverse effects | Enzyme-Linked Immunosorbent Assay | Immunization - methods | Anemia - chemically induced | Immunization, Secondary - methods | HIV-1 - genetics | HIV-1 - immunology | nef Gene Products, Human Immunodeficiency Virus - genetics | nef Gene Products, Human Immunodeficiency Virus - immunology | Interferon-gamma - immunology | Adolescent | Antibodies, Viral - immunology | Human Immunodeficiency Virus Proteins - genetics | T-Lymphocytes - immunology | AIDS Vaccines - administration & dosage | gag Gene Products, Human Immunodeficiency Virus - immunology | Interferon-gamma - blood | Cohort Studies | Oligomers | AIDS vaccines | Adenoviruses | Immunotherapy | DNA | Clinical trials | Product development | Interferon | Biological response modifiers | T cells | HIV (Viruses) | Antigenic determinants | Health care | CD8 antigen | Antibodies | Lymphocytes T | Infections | Vaccines | Epidemiology | Randomization | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Inserts | Deoxyribonucleic acid--DNA | Enzyme-linked immunosorbent assay | Recombinant | Binding | Medical research | Immunoglobulins | Cytokines | Epitopes | Immune response (humoral) | CD4 antigen | Disease prevention | Hospitals | Infectious diseases | Immunogenicity | γ-Interferon | Adults | Cancer | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | HIV | Human immunodeficiency virus
Journal Article
Molecular Therapy, ISSN 1525-0016, 05/2017, Volume 25, Issue 5, pp. 1168 - 1186
CRISPR-associated protein 9 (Cas9)-mediated genome editing provides a promising cure for HIV-1/AIDS; however, gene delivery efficiency in vivo remains an... 
genome editing | humanized BLT mice | animal models | viral latency | HIV | AAV | Tg26 mice | gene therapy | Cas9 | gRNA | EFFICIENT DELIVERY | MEDICINE, RESEARCH & EXPERIMENTAL | GENE EDITING TECHNOLOGIES | PACKAGING CAPACITY | LENTIVIRAL VECTORS | ADENOASSOCIATED VIRAL VECTORS | STAPHYLOCOCCUS-AUREUS CAS9 | CRISPR-CAS9 NUCLEASES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CRISPR/CAS9 SYSTEM | GENETICS & HEREDITY | MODULATES PROLIFERATION | NEURAL PRECURSOR CELLS | Oligonucleotides - genetics | Dependovirus - genetics | Endonucleases - genetics | Staphylococcus aureus - enzymology | RNA, Guide - genetics | RNA, Guide - metabolism | Humans | HIV Long Terminal Repeat | pol Gene Products, Human Immunodeficiency Virus - metabolism | Endonucleases - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | HIV Infections - pathology | Proviruses - genetics | Base Sequence | Clustered Regularly Interspaced Short Palindromic Repeats | gag Gene Products, Human Immunodeficiency Virus - genetics | pol Gene Products, Human Immunodeficiency Virus - genetics | Disease Models, Animal | Genome, Viral | HIV-1 - metabolism | Dependovirus - metabolism | Genetic Vectors - chemistry | HIV Infections - virology | Bacterial Proteins - genetics | Genetic Vectors - metabolism | Mice, Transgenic | HIV-1 - genetics | Proviruses - metabolism | Staphylococcus aureus - chemistry | Oligonucleotides - metabolism | Animals | CRISPR-Cas Systems | HIV Infections - therapy | Bacterial Proteins - metabolism | Gene Editing - methods | Mice | Genetic Therapy - methods | Neuroimaging | Animal models | Bioluminescence | Intravenous administration | Genes | Liver | Clinical trials | Chronic infection | Infections | Genomes | Thymus | Acquired immune deficiency syndrome--AIDS | Efficiency | Transgenic animals | Human immunodeficiency virus--HIV | Bone marrow | Colon | Deoxyribonucleic acid--DNA | Spleen | CRISPR | Gene transfer | Advisors | Transgenic mice | Ribonucleic acid--RNA | Progenitor cells | Polymerase chain reaction | Studies | Genotyping | Neural stem cells | Original
Journal Article
Nature, ISSN 0028-0836, 01/2015, Volume 517, Issue 7534, pp. 381 - 385
Despite antiretroviral therapy (ART), human immunodeficiency virus (HIV)-1 persists in a stable latent reservoir(1,2), primarily in resting memory CD4(+) T... 
IMMUNODOMINANCE | VIREMIA | DESIGN | VIRUS | RECOGNITION | STABILITY | MULTIDISCIPLINARY SCIENCES | VACCINE | ANTIRETROVIRAL THERAPY | INFECTION | VIRAL RESERVOIR | Anti-HIV Agents - pharmacology | Humans | Epitopes, T-Lymphocyte - genetics | Male | RNA, Viral - blood | Anti-HIV Agents - administration & dosage | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | HIV-1 - growth & development | Genes, Viral - genetics | Anti-HIV Agents - therapeutic use | Female | Epitopes, T-Lymphocyte - immunology | gag Gene Products, Human Immunodeficiency Virus - genetics | CD4-Positive T-Lymphocytes - virology | Chronic Disease - drug therapy | HIV Infections - blood | T-Lymphocytes, Cytotoxic - immunology | HIV-1 - drug effects | CD4-Positive T-Lymphocytes - cytology | HIV Infections - virology | Virus Replication - immunology | Acute Disease - therapy | HIV-1 - genetics | Mutation - genetics | HIV-1 - immunology | Animals | HIV Infections - drug therapy | Mice | Viral Load - drug effects | Virus Latency - immunology | gag Gene Products, Human Immunodeficiency Virus - immunology | Genes, Dominant - genetics | Virus Latency - genetics | Immune response | AIDS treatment | AIDS (Disease) | Physiological aspects | Research | AIDS research | T cells | Properties | Antigens | Peptides | Lymphocytes | Human immunodeficiency virus--HIV | Infections | Mutation | Gene expression | Patients
Journal Article
Journal Article
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 7/2009, Volume 186, Issue 2, pp. 255 - 268
Autophagy is a cytoplasmic degradative pathway that can participate in biosynthetic processes, as in the yeast Cvt pathway, but is more commonly known for its... 
T lymphocytes | HIV | Virions | Antibodies | Viruses | AIDS | Cell membranes | Macrophages | Organelles | HIV 1 | MYCOBACTERIUM-TUBERCULOSIS | ADAPTIVE IMMUNITY | TYPE-1 NEF | NEF PROTEIN | PHOSPHATIDYLINOSITOL 3-KINASE | TRAFFICKING | INFECTION | HUMAN-IMMUNODEFICIENCY-VIRUS | PLASMA-MEMBRANE | CELL | CELL BIOLOGY | RNA, Small Interfering - genetics | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Autophagy - physiology | Recombinant Fusion Proteins - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | HIV-1 - physiology | Macrophages - virology | Apoptosis Regulatory Proteins - genetics | nef Gene Products, Human Immunodeficiency Virus - metabolism | Membrane Proteins - metabolism | gag Gene Products, Human Immunodeficiency Virus - genetics | Beclin-1 | Biomarkers - metabolism | Cell Line | Macrophages - ultrastructure | Ubiquitin-Activating Enzymes - genetics | Membrane Proteins - genetics | Ubiquitin-Activating Enzymes - metabolism | Apoptosis Regulatory Proteins - metabolism | Autophagy-Related Protein 7 | Animals | nef Gene Products, Human Immunodeficiency Virus - genetics | Recombinant Fusion Proteins - genetics | Virus Replication - physiology | RNA, Small Interfering - metabolism | Virus diseases | Physiological aspects | HIV (Viruses)
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e23293
HIV proteins target host hub proteins for transient binding interactions. The presence of viral proteins in the infected cell results in out-competition of... 
REPLICATION | PHOSPHORYLATION | TAT | MULTIDISCIPLINARY SCIENCES | KINASE | IMMUNODEFICIENCY-VIRUS TYPE-1 | SH3 DOMAINS | SHORT LINEAR MOTIFS | BINDING | VIRAL-INFECTION | NEF | rev Gene Products, Human Immunodeficiency Virus - chemistry | Humans | env Gene Products, Human Immunodeficiency Virus - metabolism | rev Gene Products, Human Immunodeficiency Virus - metabolism | nef Gene Products, Human Immunodeficiency Virus - chemistry | tat Gene Products, Human Immunodeficiency Virus - chemistry | CREB-Binding Protein - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | env Gene Products, Human Immunodeficiency Virus - genetics | Human Immunodeficiency Virus Proteins - chemistry | Databases, Protein | nef Gene Products, Human Immunodeficiency Virus - metabolism | gag Gene Products, Human Immunodeficiency Virus - genetics | env Gene Products, Human Immunodeficiency Virus - chemistry | Protein Structure, Tertiary | Amino Acid Sequence | Calmodulin - metabolism | Protein Structure, Secondary | tat Gene Products, Human Immunodeficiency Virus - genetics | Models, Molecular | gag Gene Products, Human Immunodeficiency Virus - chemistry | Binding Sites - genetics | Human Immunodeficiency Virus Proteins - metabolism | Proteins - genetics | Protein Interaction Mapping - methods | Proteins - metabolism | nef Gene Products, Human Immunodeficiency Virus - genetics | Hydrophobic and Hydrophilic Interactions | Protein Binding | Human Immunodeficiency Virus Proteins - genetics | rev Gene Products, Human Immunodeficiency Virus - genetics | Amino Acid Motifs - genetics | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Casein Kinase II - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | tat Gene Products, Human Immunodeficiency Virus - metabolism | Physiological aspects | Viral proteins | HIV (Viruses) | Genomics | Protein binding | Phenotypes | Phosphorylation | Hot spots | Crosstalk | Amino acid sequence | Viruses | Genomes | Kinases | Proteins | Conserved sequence | Human immunodeficiency virus--HIV | Computer applications | Mutation | Localization | Bioinformatics | Binding sites | HIV | Human immunodeficiency virus
Journal Article
Journal of Virology, ISSN 0022-538X, 2015, Volume 89, Issue 10, pp. 5330 - 5339
Journal Article
Nature, ISSN 0028-0836, 04/2009, Volume 458, Issue 7238, pp. 641 - 645
Journal Article
Journal Article