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1. Full Text In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models
by Yin, Chaoran and Zhang, Ting and Qu, Xiying and Zhang, Yonggang and Putatunda, Raj and Xiao, Xiao and Li, Fang and Xiao, Weidong and Zhao, Huaqing and Dai, Shen and Qin, Xuebin and Mo, Xianming and Young, Won-Bin and Khalili, Kamel and Hu, Wenhui
Molecular therapy, ISSN 1525-0016, 05/2017, Volume 25, Issue 5, pp. 1168 - 1186
genome editing | humanized BLT mice | animal models | viral latency | HIV | AAV | Tg26 mice | gene therapy | Cas9 | gRNA | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Oligonucleotides - genetics | Dependovirus - genetics | Endonucleases - genetics | Staphylococcus aureus - enzymology | RNA, Guide - genetics | RNA, Guide - metabolism | Humans | HIV Long Terminal Repeat | pol Gene Products, Human Immunodeficiency Virus - metabolism | Endonucleases - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | HIV Infections - pathology | Proviruses - genetics | Base Sequence | Clustered Regularly Interspaced Short Palindromic Repeats | gag Gene Products, Human Immunodeficiency Virus - genetics | pol Gene Products, Human Immunodeficiency Virus - genetics | Disease Models, Animal | Genome, Viral | HIV-1 - metabolism | Dependovirus - metabolism | Genetic Vectors - chemistry | HIV Infections - virology | Bacterial Proteins - genetics | Genetic Vectors - metabolism | Mice, Transgenic | HIV-1 - genetics | Proviruses - metabolism | Staphylococcus aureus - chemistry | Oligonucleotides - metabolism | Animals | CRISPR-Cas Systems | HIV Infections - therapy | Bacterial Proteins - metabolism | Gene Editing - methods | Mice | Genetic Therapy - methods | Neuroimaging | Animal models | Bioluminescence | Intravenous administration | Genes | Liver | Clinical trials | Chronic infection | Infections | Genomes | Thymus | Acquired immune deficiency syndrome--AIDS | Efficiency | Transgenic animals | Human immunodeficiency virus--HIV | Bone marrow | Colon | Deoxyribonucleic acid--DNA | Spleen | CRISPR | Gene transfer | Advisors | Transgenic mice | Ribonucleic acid--RNA | Progenitor cells | Polymerase chain reaction | Studies | Genotyping | Neural stem cells | Index Medicus | Original
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2. Full Text Autophagy Pathway Intersects with HIV-1 Biosynthesis and Regulates Viral Yields in Macrophages
by George B. Kyei and Christina Dinkins and Alexander S. Davis and Esteban Roberts and Sudha B. Singh and Chunsheng Dong and Li Wu and Eiki Kominami and Takashi Ueno and Akitsugu Yamamoto and Maurizio Federico and Antonito Panganiban and Isabelle Vergne and Vojo Deretic
The Journal of cell biology, ISSN 0021-9525, 7/2009, Volume 186, Issue 2, pp. 255 - 268
T lymphocytes | HIV | Virions | Antibodies | Viruses | AIDS | Cell membranes | Macrophages | Organelles | HIV 1 | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Autophagy - physiology | Recombinant Fusion Proteins - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | HIV-1 - physiology | Macrophages - virology | Apoptosis Regulatory Proteins - genetics | nef Gene Products, Human Immunodeficiency Virus - metabolism | Membrane Proteins - metabolism | gag Gene Products, Human Immunodeficiency Virus - genetics | Beclin-1 | Biomarkers - metabolism | Cell Line | Macrophages - ultrastructure | Ubiquitin-Activating Enzymes - genetics | Membrane Proteins - genetics | Ubiquitin-Activating Enzymes - metabolism | Apoptosis Regulatory Proteins - metabolism | Autophagy-Related Protein 7 | Animals | nef Gene Products, Human Immunodeficiency Virus - genetics | Recombinant Fusion Proteins - genetics | Virus Replication - physiology | RNA, Small Interfering - metabolism | Virus diseases | Physiological aspects | HIV (Viruses) | Proteins | Human immunodeficiency virus--HIV | Biochemistry | Biosynthesis | Molecular biology | Cells | Index Medicus | s
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3. Full Text Simultaneous Cell-to-Cell Transmission of Human Immunodeficiency Virus to Multiple Targets through Polysynapses
by Dominika Rudnicka and Jérôme Feldmann and Françoise Porrot and Steve Wietgrefe and Stéphanie Guadagnini and Marie-Christine Prévost and Jérôme Estaquier and Ashley T. Haase and Nathalie Sol-Foulon and Olivier Schwartz
Journal of Virology, ISSN 0022-538X, 06/2009, Volume 83, Issue 12, pp. 6234 - 6246
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | Microscopy, Electron, Transmission | Microscopy, Electron, Scanning | Jurkat Cells | HIV Infections - virology | Humans | Pseudopodia - virology | CD4-Positive T-Lymphocytes - ultrastructure | Lymphocyte Function-Associated Antigen-1 - metabolism | env Gene Products, Human Immunodeficiency Virus - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | Animals | HIV-1 - physiology | Virus Replication | Female | Macaca | CD4-Positive T-Lymphocytes - virology | Index Medicus | HIV Infections | HIV-1 | Parasitology | gag Gene Products, Human Immunodeficiency Virus | Pseudopodia | env Gene Products, Human Immunodeficiency Virus | Life Sciences | Microbiology and Parasitology | Lymphocyte Function-Associated Antigen-1 | CD4-Positive T-Lymphocytes | Virus-Cell Interactions
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4. Full Text An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses
by Harari, Alexandre and Bart, Pierre-Alexandre and Stöhr, Wolfgang and Tapia, Gonzalo and Garcia, Miguel and Medjitna-Rais, Emmanuelle and Burnet, Séverine and Cellerai, Cristina and Erlwein, Otto and Barber, Tristan and Moog, Christiane and Liljestrom, Peter and Wagner, Ralf and Wolf, Hans and Kraehenbuhl, Jean-Pierre and Esteban, Mariano and Heeney, Jonathan and Frachette, Marie-Joelle and Tartaglia, James and McCormack, Sheena and Babiker, Abdel and Weber, Jonathan and Pantaleo, Giuseppe
The Journal of experimental medicine, ISSN 0022-1007, 01/2008, Volume 205, Issue 1, pp. 63 - 77
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Enzyme-Linked Immunosorbent Assay - methods | Epitope Mapping | Viral Vaccines - therapeutic use | Peptides - chemistry | Humans | CD4-Positive T-Lymphocytes - metabolism | AIDS Vaccines - therapeutic use | Vaccines | AIDS Vaccines - chemistry | Phenotype | env Gene Products, Human Immunodeficiency Virus - genetics | Animals | Codon | nef Gene Products, Human Immunodeficiency Virus - genetics | Viral Vaccines - chemistry | CD8-Positive T-Lymphocytes - metabolism | gag Gene Products, Human Immunodeficiency Virus - genetics | Index Medicus | Medicin och hälsovetenskap
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5. Full Text Construction of stable packaging cell lines for clinical lentiviral vector production
by Sanber, Khaled S and Knight, Sean B and Stephen, Sam L and Bailey, Ranbir and Escors, David and Minshull, Jeremy and Santilli, Giorgia and Thrasher, Adrian J and Collins, Mary K and Takeuchi, Yasuhiro
Scientific reports, ISSN 2045-2322, 03/2015, Volume 5, Issue 1, pp. 9021 - 9021
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | HIV-1 - metabolism | Gene Expression | Viral Envelope Proteins - genetics | Protein Precursors - genetics | Humans | Homologous Recombination | pol Gene Products, Human Immunodeficiency Virus - metabolism | HIV-1 - genetics | Virus Assembly | rev Gene Products, Human Immunodeficiency Virus - metabolism | Genetic Vectors - genetics | Protein Precursors - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | Retroviridae - metabolism | Retroviridae - genetics | HEK293 Cells | Viral Envelope Proteins - metabolism | Lentivirus - genetics | rev Gene Products, Human Immunodeficiency Virus - genetics | gag Gene Products, Human Immunodeficiency Virus - genetics | pol Gene Products, Human Immunodeficiency Virus - genetics | Transfection | Gene transfer | Cell lines | Clinical trials | Cytotoxicity | Genomes | Recombinase | Cre recombinase | Index Medicus
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6. Full Text Predominant Mode of Human Immunodeficiency Virus Transfer between T Cells Is Mediated by Sustained Env-Dependent Neutralization-Resistant Virological Synapses
by Ping Chen and Wolfgang Hübner and Matthew A. Spinelli and Benjamin K. Chen
Journal of Virology, ISSN 0022-538X, 11/2007, Volume 81, Issue 22, pp. 12582 - 12595
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | Green Fluorescent Proteins - metabolism | Immune Sera - immunology | Sequence Deletion | Green Fluorescent Proteins - analysis | Membrane Fusion | Jurkat Cells | Humans | env Gene Products, Human Immunodeficiency Virus - metabolism | gag Gene Products, Human Immunodeficiency Virus - analysis | Cell Adhesion | Virus Internalization | CD4-Positive T-Lymphocytes - immunology | gag Gene Products, Human Immunodeficiency Virus - metabolism | HIV-1 - immunology | Receptors, CCR5 - metabolism | env Gene Products, Human Immunodeficiency Virus - genetics | Cytoskeleton - metabolism | Antibodies, Viral - immunology | CD4-Positive T-Lymphocytes - virology | Index Medicus | Virus-Cell Interactions
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7. Full Text SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef
by Usami, Yoshiko and Wu, Yuanfei and Göttlinger, Heinrich G
Nature (London), ISSN 0028-0836, 10/2015, Volume 526, Issue 7572, pp. 218 - 223
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - pharmacology | Virion - chemistry | Host-Pathogen Interactions - drug effects | Membrane Proteins - pharmacology | Neoplasm Proteins - metabolism | Receptors, Cell Surface - antagonists & inhibitors | Membrane Proteins - deficiency | HIV-1 - growth & development | HIV-1 - physiology | HIV-1 - chemistry | Gene Deletion | nef Gene Products, Human Immunodeficiency Virus - metabolism | Membrane Proteins - metabolism | Cell Line | Virus Replication - drug effects | nef Gene Products, Human Immunodeficiency Virus - deficiency | HIV-1 - drug effects | Down-Regulation | HIV Infections - virology | Virion - physiology | CD4-Positive T-Lymphocytes - metabolism | Receptors, Cell Surface - metabolism | Gene Products, gag - metabolism | Protein Transport | Virion - drug effects | Membrane Proteins - antagonists & inhibitors | Receptors, Cell Surface - deficiency | HIV Infections - drug therapy | Neoplasm Proteins - deficiency | Virion - growth & development | Leukemia Virus, Murine - chemistry | Development and progression | Genetic aspects | Virulence (Microbiology) | Viral proteins | Properties | HIV infection | Proteins | Genomes | Immunology | Mutation | Human immunodeficiency virus--HIV | Cells | Index Medicus
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8. Full Text Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
by Neil, Stuart J. D and Zang, Trinity and Bieniasz, Paul D
Nature (London), ISSN 0028-0836, 01/2008, Volume 451, Issue 7177, pp. 425 - 430
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Antiviral agents | Biological and medical sciences | Medical sciences | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Viral Regulatory and Accessory Proteins - antagonists & inhibitors | Interferon-alpha - pharmacology | Membrane Glycoproteins - metabolism | Oligonucleotide Array Sequence Analysis | Humans | GPI-Linked Proteins | Gene Expression Profiling | Antigens, CD - genetics | Antigens, CD - metabolism | gag Gene Products, Human Immunodeficiency Virus - metabolism | Endocytosis | Membrane Glycoproteins - antagonists & inhibitors | Leukemia Virus, Murine - metabolism | Cell Line | HIV-1 - metabolism | HIV Infections - virology | Mutant Proteins - genetics | Mutant Proteins - metabolism | Virion - metabolism | Viral Regulatory and Accessory Proteins - metabolism | Membrane Glycoproteins - genetics | Protein Transport | Human Immunodeficiency Virus Proteins - metabolism | Virus Replication | HIV Infections - therapy | Human Immunodeficiency Virus Proteins - antagonists & inhibitors | Cell Membrane - virology | HeLa Cells | HIV Infections - metabolism | Cellular proteins | Control | Genetic aspects | Viral proteins | HIV (Viruses) | Health aspects | Proteins | Human immunodeficiency virus | Cellular biology | HIV | Virology | Cell adhesion & migration | Index Medicus
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