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Journal of Lipid Research, ISSN 0022-2275, 09/2015, Volume 56, Issue 9, pp. 1747 - 1761
Ganglioside GM2 is the major lysosomal storage compound of Tay-Sachs disease. It also accumulates in Niemann-Pick disease types A and B with primary storage of... 
Supplementary lipid transfer protein | Ceramide | Sphingomyelin | Hexahistidine-tag | Endosomal | Bis(monoacylglycero)phosphate | Cholesterol | Lysosomal lipids | CHOLESTEROL TRANSFER | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-HEXOSAMINIDASE-A | HUMAN GM2-ACTIVATOR PROTEIN | endosomal | lipid transfer protein | RAT-LIVER LYSOSOMES | C2 PROTEIN | IMMUNOELECTRON MICROSCOPY | bis(monoacylglycero)phosphate | NIEMANN-PICK-DISEASE | ceramide | hexahistidine-tag | MOBILIZES LIPIDS | sphingomyelin | cholesterol | lysosomal lipids | ACID SPHINGOMYELINASE ACTIVITY | EXTRACTION CAPACITY | Surface Plasmon Resonance | Lysophospholipids - administration & dosage | Ceramides - metabolism | G(M2) Activator Protein - metabolism | Sphingomyelins - metabolism | Hydrolysis - drug effects | Membrane Lipids - genetics | G(M2) Activator Protein - genetics | Humans | beta-Hexosaminidase alpha Chain - metabolism | Monoglycerides - administration & dosage | Niemann-Pick Diseases - metabolism | Cholesterol - metabolism | Niemann-Pick Diseases - pathology | Cholesterol - genetics | Tay-Sachs Disease - genetics | G(M2) Ganglioside - metabolism | HEK293 Cells | Tay-Sachs Disease - metabolism | Fluorescence Resonance Energy Transfer | Membrane Lipids - metabolism | Liposomes - metabolism | Tay-Sachs Disease - pathology | Niemann-Pick Diseases - genetics
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