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1. Full Text Association of Triglyceride-Lowering LPL Variants and LDL-C–Lowering LDLR Variants With Risk of Coronary Heart Disease
by Ference, Brian A and Kastelein, John J. P and Ray, Kausik K and Ginsberg, Henry N and Chapman, M. John and Packard, Chris J and Laufs, Ulrich and Oliver-Williams, Clare and Wood, Angela M and Butterworth, Adam S and Di Angelantonio, Emanuele and Danesh, John and Nicholls, Stephen J and Bhatt, Deepak L and Sabatine, Marc S and Catapano, Alberico L
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 01/2019, Volume 321, Issue 4, pp. 364 - 373
Coronary Disease/blood | Cholesterol, LDL/blood | Genetic Predisposition to Disease | Apolipoproteins B/blood | Loss of Function Mutation | Prospective Studies | Humans | Middle Aged | Risk Factors | Male | Case-Control Studies | Lipoprotein Lipase/genetics | Genetic Variation | Metabolic Networks and Pathways | Mendelian Randomization Analysis | Triglycerides/blood | Female | Receptors, LDL/genetics | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Coronary Disease - blood | Receptors, LDL - genetics | Lipoprotein Lipase - genetics | Apolipoproteins B - blood | Coronary Disease - genetics | Triglycerides - blood | Cholesterol, LDL - blood | Lipoprotein Lipase - metabolism | Care and treatment | Genetic variation | Cholesterol, LDL | Genetic aspects | Research | Health aspects | Coronary heart disease | Risk factors | Myocardial infarction | Lipoproteins (low density) | Health risks | Risk | Cardiovascular disease | Lipids | Triglycerides | Lipoprotein lipase | LDLR gene | Lipase | Coronary artery disease | Cholesterol | Apolipoprotein B | Lipoproteins | Randomization | Genetic analysis | Lipoprotein (low density) receptors | Infarction | Cardiovascular diseases | Health risk assessment | Heart diseases | Index Medicus | Abridged Index Medicus | Original Investigation
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2. Full Text SLCO1B1 Variants and Statin-Induced Myopathy — A Genomewide Study
by Meade, T and Collins, R and Armitage, J and Parish, S and Barton, J and Bray, C and Wincott, E and Bowman, L and Clarke, R and Graham, I and Simpson, D and Warlow, C and Tobert, J and Musliner, T and Doll, R and Fox, K.M and Hill, C and Sandercock, P and Peto, R and Webster, J and Jamieson, J and Nixon, A and Lackie, S and Thompson, J and Brown, M and Blackwood, S and Morgan, M and Rhoden, W and Saeed, B and Houghton, M and Nicholson, A and Simpson, C and Hoburn, B and Cooper, I and Gallivan, A and Pickerell, E and Hancock, J and Watkinson, J and Burbridge, W and Kitchen, M and O'Leary, H and Verow, C and Meynell, L and Rollinson, L and Bain, S and Jones, A and Jewkes, C and Russon, C and Bateson, M and Gill, P and Stansbie, D and Bayly, G and Andrews, G and Halestrap, M and Meredith, J and Best, R and Appleyard, D and Wareing, H and Holmes, K and Holt, J and Kenyon, M and White, C and Khalifa, M and Newton, D and Wass, A and Watkinson, R and Creamer, J and Bethell, A and Butler, C and Washington, M and Weston, E and Machin, J and Cleaver, K and Wray, R and Sinclair, J and Van Aalst, A and Been, M and Mattu, R and Burke, A and Gill, L and Walton, E and Cowley, M and Robson, H and Graham, A and Rose, G and Kerr, M and Mallinson, J and Peascod, B and Scott, A and Donnelly, R and Gibson, T and Hannah, J and Henshaw, L and Margetts, M and Pearson, N and Frost, S and Murray, S and Marshall, A and Went, J and Simmonds, J and ... and The SEARCH Collaborative Group and SEARCH Collaborative Grp and SEARCH Collaborative Group and Sahlgrenska akademin and Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin and Institute of Medicine, Department of Emergeny and Cardiovascular Medicine and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
The New England journal of medicine, ISSN 0028-4793, 08/2008, Volume 359, Issue 8, pp. 789 - 799
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Simvastatin - therapeutic use | Simvastatin - adverse effects | Humans | Middle Aged | Diabetes Mellitus - drug therapy | Genotype | Male | Risk | Genetic Markers | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Organic Anion Transporters - genetics | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Myocardial Infarction - drug therapy | Arterial Occlusive Diseases - drug therapy | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Female | Aged | Myocardial Infarction - prevention & control | Polymorphism, Single Nucleotide | Chromosomes, Human, Pair 12 | Muscular Diseases - chemically induced | Muscular Diseases - genetics | Solute Carrier Organic Anion Transporter Family Member 1b1 | Complications and side effects | Analysis | Muscle diseases | Genetic aspects | Dosage and administration | Single nucleotide polymorphisms | Risk factors | Statins | Drug therapy | Kinases | Drug dosages | Cholesterol | Index Medicus | Abridged Index Medicus | MEDICIN OCH HÄLSOVETENSKAP | Single Nucleotide | genetics | Arterial Occlusive Diseases | pharmacokinetics | Muscular Diseases | Hydroxymethylglutaryl-CoA Reductase Inhibitors | Chromosomes | MEDICAL AND HEALTH SCIENCES | Human | drug therapy | chemically induced | Simvastatin | prevention & control | Diabetes Mellitus | Myocardial Infarction | Pair 12 | Organic Anion Transporters | adverse effects | therapeutic use | Polymorphism
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3. Mendelian randomization
: methods for using genetic variants in causal estimation
by Burgess, Stephen and Thompson, Simon G., author
2015, Chapman & Hall/CRC interdisciplinary statics series, ISBN 1466573171, xiv, 210
Statistics as Topic | Statistical methods | Genetics, Medical | Genetic epidemiology | Epidemiologic Methods | Medical genetics | Statistical Theory & Methods | Statistics for the Biological Sciences | Epidemiology
Book
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4. Full Text Histone variants - ancient wrap artists of the epigenome
by Henikoff, Steven and Talbert, Paul B
Nature reviews. Molecular cell biology, ISSN 1471-0072, 04/2010, Volume 11, Issue 4, pp. 264 - 275
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Genetic Variation | Animals | Histones - genetics | DNA Repair | Epigenesis, Genetic | Humans | Protein Processing, Post-Translational | Histones | Physiological aspects | DNA replication | DNA binding proteins | Research | DNA repair | Index Medicus
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5. Full Text TREM2 Variants in Alzheimer's Disease
by Guerreiro, Rita and Wojtas, Aleksandra and Bras, Jose and Carrasquillo, Minerva and Rogaeva, Ekaterina and Majounie, Elisa and Cruchaga, Carlos and Sassi, Celeste and Kauwe, John S.K and Younkin, Steven and Hazrati, Lilinaz and Collinge, John and Pocock, Jennifer and Lashley, Tammaryn and Williams, Julie and Lambert, Jean-Charles and Amouyel, Philippe and Goate, Alison and Rademakers, Rosa and Morgan, Kevin and Powell, John and St. George-Hyslop, Peter and Singleton, Andrew and Hardy, John and Alzheimer Genetic Anal Grp and EADI Consortium and GERAD Consortium and UKBE Consortium and Alzheimer Genetic Analysis Group
The New England journal of medicine, ISSN 0028-4793, 01/2013, Volume 368, Issue 2, pp. 117 - 127
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Neurology | Organic mental disorders. Neuropsychology | General aspects | Psychology. Psychoanalysis. Psychiatry | Adult and adolescent clinical studies | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Psychopathology. Psychiatry | Biological and medical sciences | Medical sciences | Genome-Wide Association Study | Membrane Glycoproteins - metabolism | Mice, Inbred A | Humans | Risk Factors | Genotype | Genotyping Techniques | RNA, Messenger - metabolism | Alzheimer Disease - pathology | Membrane Glycoproteins - genetics | Genetic Variation | Exome - genetics | Animals | Brain - pathology | Heterozygote | Aged | Mice | Mutation | Alzheimer Disease - genetics | Receptors, Immunologic - genetics | Sequence Analysis, DNA - methods | Receptors, Immunologic - metabolism | Gene mutations | Genetic variation | Causes of | Genetic aspects | Research | Apolipoproteins | Alzheimer's disease | Health aspects | Proteins | Genetics | Genomes | Alzheimers disease | Index Medicus | Abridged Index Medicus
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