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Methods in Cell Biology, ISSN 0091-679X, 2016, Volume 135, pp. 121 - 147
Conference Proceeding
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2018, Volume 115, Issue 31, p. E7379
The precise correction of genetic mutations at the nucleotide level is an attractive permanent therapeutic strategy for human disease. However, despite... 
Genomics | Liver | DNA damage | Homologous recombination | IL2RG gene | Insertion | Viruses | Homology | Genomes | Myocytes | Hematopoietic stem cells | Nuclease | Genetic modification | Deoxyribonucleic acid--DNA | CD34 antigen | BRCA2 protein | Medical treatment | Breast cancer | Loci | Endothelial cells | Hemopoiesis | Hepatocytes | Adenoviruses | Stem cells | Mutation | Genetic recombination
Journal Article
Molecular Therapy, ISSN 1525-0016, 10/2019, Volume 27, Issue 10, pp. 1726 - 1736
Adeno-associated virus (AAV) vectors are frequently used as donor templates for genome editing by homologous recombination. Although modification rates are... 
hematopoietic stem cell | genome editing | AAV vectors | homology-directed repair | targeted nucleases | NONHUMAN-PRIMATES | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | ZFN | CRISPR/CAS9 | ADENOASSOCIATED VIRUS TYPE-2 | IN-VITRO | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | GENE-TRANSFER | EXPRESSION | VECTORS | HEMATOPOIETIC STEM
Journal Article
DNA Repair, ISSN 1568-7864, 10/2019, Volume 82, p. 102691
CRISPR technologies greatly foster genome editing in mammalian cells through site-directed DNA double strand breaks (DSBs). However, precise editing outcomes,... 
Genome editing | Alternative end-joining pathways | Homologous recombination | Gene correction | COMPLEX | STRAND BREAK REPAIR | PROTEIN | MECHANISM | KINASE | RAD51 | GENE | GENETICS & HEREDITY | DIRECTED REPAIR | TOXICOLOGY | CAS9 | DNA-REPAIR
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2019, Volume 116, Issue 1, pp. 337 - 337
Journal Article
by Zhang, Y and Huang, H and Zhang, B and Lin, S
Methods in Cell Biology, ISSN 0091-679X, 2016, Volume 135, pp. 107 - 120
Conference Proceeding
Nucleic Acids Research, ISSN 0305-1048, 11/2013, Volume 41, Issue 20, pp. e193 - e193
Journal Article
Journal Article