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Pathogens, ISSN 2076-0817, 11/2019, Volume 8, Issue 4, p. 258
Pseudorabies virus (PRV), a member of the Herpesviridae, is the causative agent of an acute infectious disease in a variety of animals. The emergence of a... 
prv | germacrone | antiviral
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2019, Volume 518, Issue 3, pp. 560 - 564
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease. The imbalance of T helper type 1 (Th1) and Th2 immune responses contributes to the... 
NF-κB | Germacrone | Rheumatoid arthritis | Th1/Th2 imbalance
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2014, Volume 15, Issue 22, pp. 9997 - 10001
Background: Curdione, one of the major components of Curcuma zedoaria, has been reported to possess various biological activities. It thus might be a candidate... 
MCF-7 cells | Curdione | Proliferation | Apoptosis | proliferation | ONCOLOGY | CURCUMA | ESSENTIAL OIL | apoptosis | GERMACRONE
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 10/2019, Volume 569, p. 118586
The main objective of this study was to develop a novel self-assembled micelle system to improve the oral bioavailability of the water-insoluble and thermal... 
Supercritical fluid | Oral bioavailability | Soluplus | Germacrone | Self-assembled micelles | DSPE-PEG2000 | DRUG-DELIVERY | BLOCK-COPOLYMER MICELLES | MIXED MICELLES | FORMULATION | Solupins (R) | SOLUBILITY | IN-VITRO | TRANSPORT | DSPE-PEG | PHARMACOLOGY & PHARMACY | CARBON-DIOXIDE | LIPOSOMES | PEGYLATION
Journal Article
by Jung, Y and Lee, J and Kim, HK and Moon, BC and Ji, Y and Ryu, DH and Hwang, GS
ANALYST, ISSN 0003-2654, 2012, Volume 137, Issue 23, pp. 5597 - 5606
Curcuma is used to treat skin diseases and colic inflammatory disorders, and in insect repellants and antimicrobial and antidiabetic medications. Two Curcuma... 
CHEMISTRY, ANALYTICAL | PLANT METABOLOMICS | NUCLEAR-MAGNETIC-RESONANCE | ESSENTIAL OIL | NMR-BASED METABOLOMICS | IDENTIFICATION | GEOGRAPHICAL ORIGIN | GERMACRONE | CURDIONE | RHIZOMES
Journal Article
RECORDS OF NATURAL PRODUCTS, ISSN 1307-6167, 2016, Volume 10, Issue 1, pp. 93 - 102
The essential oils (EOs) from the leaves and the flowers of Smyrnium olusatrum L., growing wild in the island of Cephalonia (Greece), were analyzed by GC-FID... 
FRUITS | CHEMISTRY, MEDICINAL | LEAVES | APIACEAE | isolation | (-) germacrone | DIFFERENT PARTS | CHROMATOGRAPHY | (+) furanoeremophil-1-one | antifungal activity | PLANT SCIENCES | STEMS | VOLATILE CONSTITUENTS | FURANOSESQUITERPENES | essential oil | CHEMISTRY, APPLIED | Smyrnium olusatrum | furanodiene | GERMACRONE | RHIZOMES
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 05/2018, Volume 288, pp. 32 - 37
Multidrug resistance (MDR) usually causes chemotherapy failure of chronic myelogenous leukemia (CML). Germacrone is a terpenoid compound and has been reported... 
P-glycoprotein | Chronic myelogenous leukemia | MDR1 | Germacrone | Multidrug resistance | Adriamycin | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHARMACOLOGY & PHARMACY | TOXICOLOGY | MULTIDRUG-RESISTANCE | CHEMOTHERAPY | Chemotherapy | Anthracyclines | Chronic myeloid leukemia | RNA | Cancer | Index Medicus
Journal Article
Industrial Crops & Products, ISSN 0926-6690, 06/2018, Volume 116, pp. 41 - 45
The insecticidal and acaricidal effects of the essential oils (EO) from two populations of L (ornamental variety Bevan, VB and wild population from Hungary,... 
Geranium macrorrhizum | Essential oil | Ixodicidal | Germacrone | Chemotype | Antifeedant | AGRONOMY | LEAVES | ADULTS | OVIPOSITION | ACARI IXODIDAE | THYMOL | AGRICULTURAL ENGINEERING | TICK REPELLENTS | SPAIN | Aphididae | Esters | Insect pests
Journal Article
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, ISSN 1001-5302, 09/2017, Volume 42, Issue 18, pp. 3564 - 3571
Journal Article
CHEMISTRY-A EUROPEAN JOURNAL, ISSN 0947-6539, 05/2013, Volume 19, Issue 21, pp. 6598 - 6612
Treatment of germacrone (1) with different electrophiles, and of its epoxy derivatives germacrone-4,5-epoxide (2), germacrone-1,10-epoxide (3) and... 
4-EXO CYCLIZATIONS | terpenes | ring closure | AB-INITIO | TEMPLATE CATALYSIS | CHEMISTRY, MULTIDISCIPLINARY | ZEDOARIAE RHIZOMA | ORIENTED SYNTHESIS | SESQUITERPENES | density functional calculations | MEDICINAL FOODSTUFFS | (4S,5S)-(+)-GERMACRONE 4,5-EPOXIDE | 5-EPI-ARISTOLOCHENE SYNTHASE | biosynthesis | conformational analysis
Journal Article
Industrial Crops & Products, ISSN 0926-6690, 01/2016, Volume 79, pp. 267 - 273
In this work, we investigated the chemical constituents of the essential oil extracted from the leaves of and their insecticidal and repellent activities... 
Liposcelis bostrychophila | Tribolium castaneum | Essential oil | Rhododendron thymifolium | Insecticidal activity | Germacrone | BIOACTIVITY | AGRONOMY | PSOCOPTERA | TOXICITY | IDENTIFICATION | BOTANICAL INSECTICIDES | AGRICULTURAL ENGINEERING | AERIAL PARTS | PRODUCT | INSECTS | FUMIGANTS | Beetles
Journal Article
Revista Brasileira de Farmacognosia, ISSN 0102-695X, 11/2015, Volume 25, Issue 6, pp. 612 - 618
The gorgonian Esper is an octocoral known to be source of biologically active terpenes. In this study, odoriferous compounds present in tissues were... 
Oxygenated sesquiterpenes | Phyllogorgia dilatata | Germacrones | Gorgonian | Germacrone | Fragrance | CHEMISTRY, MEDICINAL | COAST | OCTOCORALS | SESQUITERPENOIDS | CHALLENGES | 12-BETA-EPOXYPUKALIDE | PHYLLOGORGIA-DILATATA ESPER | PHARMACOLOGY & PHARMACY | 11-BETA
Journal Article
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