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PLoS ONE, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, p. e0154680
The receptor-activator of nuclear kappaB ligand (RANKL) signaling pathway plays an important role in the regulation of bone growth and mediates the formation... 
GIANT-CELL TUMOR | DENOSUMAB | MULTIDISCIPLINARY SCIENCES | Osteosarcoma - drug therapy | RANK Ligand - metabolism | Humans | Male | Antineoplastic Agents - therapeutic use | Fibrous Dysplasia of Bone - drug therapy | RNA, Messenger - metabolism | Bone Neoplasms - pathology | Giant Cell Tumor of Bone - pathology | Chondrosarcoma - genetics | Chondrosarcoma - pathology | Bone Cysts, Aneurysmal - metabolism | Bone Neoplasms - genetics | Fibrous Dysplasia of Bone - genetics | Chondroma - drug therapy | Osteoclasts - pathology | Bone Cysts, Aneurysmal - pathology | Multiple Myeloma - genetics | Osteosarcoma - pathology | Bone Cysts, Aneurysmal - drug therapy | Chondroma - genetics | Gene Expression Regulation, Neoplastic | Chondroma - metabolism | Chondroma - pathology | Bone Neoplasms - metabolism | Denosumab - therapeutic use | Multiple Myeloma - drug therapy | Giant Cell Tumor of Bone - drug therapy | RNA, Messenger - antagonists & inhibitors | Female | Bone Neoplasms - drug therapy | Giant Cell Tumor of Bone - genetics | Osteosarcoma - metabolism | Fibrous Dysplasia of Bone - pathology | RNA, Messenger - genetics | Multiple Myeloma - metabolism | Organ Specificity | Chondrosarcoma - drug therapy | Fibrous Dysplasia of Bone - metabolism | Osteoclasts - metabolism | Bone Resorption - prevention & control | RANK Ligand - genetics | Multiple Myeloma - pathology | Giant Cell Tumor of Bone - metabolism | RANK Ligand - antagonists & inhibitors | Chondrosarcoma - metabolism | Osteosarcoma - genetics | Osteoclasts - drug effects | Bone Cysts, Aneurysmal - genetics | Bone resorption | Bones | Dosage and administration | Denosumab | Growth | Analysis | Immunohistochemistry | Chondrosarcoma | Multiple myeloma | Aneurysm | Bone tumors | Metastasis | Bone surgery | Metastases | Osteoprotegerin | Signal transduction | Bone growth | Biomedical materials | Osteosarcoma | Fibrous dysplasia | Bone dysplasia | Biocompatibility | Lesions | TRANCE protein | University graduates | Statistical analysis | Bone lesions | Gene expression | Osteoclastogenesis | Signaling | Bone cancer | Hospitals | Biopsy | Stromal cells | Orthopedics | Monoclonal antibodies | Ligands | Osteoclasts | Prostate cancer | Tumors
Journal Article
Journal Article
Journal Article
Skeletal Radiology, ISSN 0364-2348, 07/2017, Volume 46, Issue 7, pp. 961 - 962
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s00256-017-2643-4 
Bone and Bones | Giant Cell Tumor of Bone | Humans | Bone Density Conservation Agents | Burns | Denosumab | Bone Neoplasms | Medical colleges | Surgery | Tumors
Journal Article
Journal of the American Academy of Orthopaedic Surgeons, ISSN 1067-151X, 02/2013, Volume 21, Issue 2, pp. 118 - 126
Journal Article
Clinical Orthopaedics and Related Research, ISSN 0009-921X, 2/2011, Volume 469, Issue 2, pp. 591 - 599
Many surgeons treat giant cell tumor of bone (GCT) with intralesional curettage. Wide resection is reserved for extensive bone destruction where joint... 
Surgical Orthopedics | Medicine & Public Health | Sports Medicine | Surgery | Orthopedics | Conservative Orthopedics | Medicine/Public Health, general | INTRALESIONAL EXCISION | PROXIMAL FIBULA | SURGERY | EN-BLOC RESECTION | TERM-FOLLOW-UP | SURGICAL-MANAGEMENT | LOCAL-CONTROL | ADJUVANT THERAPY | ORTHOPEDICS | PULMONARY METASTASES | MUSCULOSKELETAL NEOPLASMS | LONG BONES | Bone Neoplasms - mortality | Lung Neoplasms - drug therapy | Giant Cell Tumor of Bone - secondary | Lung Neoplasms - mortality | Humans | Middle Aged | Risk Factors | Male | Antineoplastic Agents - therapeutic use | Neoplasm Recurrence, Local - diagnosis | Bone Neoplasms - pathology | Bone Cements - therapeutic use | Polymethyl Methacrylate - therapeutic use | Minnesota - epidemiology | Young Adult | Disease-Free Survival | Giant Cell Tumor of Bone - drug therapy | Lung Neoplasms - secondary | Adult | Female | Giant Cell Tumor of Bone - mortality | Retrospective Studies | Bone Neoplasms - drug therapy | Chemotherapy, Adjuvant | Chemotherapy | Polymethylmethacrylate | Adjuvant treatment | Respiratory agents | Metastasis | Health aspects | Risk factors | Tumors | Cancer | Bone grafts | Demography | Lung | Adjuvants | Bone tumors | polymethylmethacrylate | Radiotherapy | Bone surgery | Survival | Metastases | Curettage | Phenols | Giant cells | Bone loss | Joints | Clinical Research
Journal Article
Journal Article
Human Pathology, ISSN 0046-8177, 10/2017, Volume 68, pp. 119 - 127
Journal Article
The Journal of Bone & Joint Surgery, ISSN 0021-9355, 03/2012, Volume 94, Issue 5, pp. 461 - 467
Journal Article
by Wang, W and Liu, XL and Wu, J and Kang, X and Xie, QY and Sheng, J and Xu, W and Liu, D and Zheng, W
MEDICINE, ISSN 0025-7974, 10/2019, Volume 98, Issue 40, p. e17445
Giant cell tumor (GCT) of bone is a locally aggressive bone tumor, which accounts for 4% to 5% of all primary bone tumors. At present, the early diagnosis and... 
METABONOMICS | ACID | biomarkers | PANCREATIC-CANCER | RATS | IDENTIFICATION | QUANTITATIVE-ANALYSIS | MASS-SPECTROMETRY | STRATEGIES | MEDICINE, GENERAL & INTERNAL | IN-VITRO | metabolomics | GENE-EXPRESSION | GCT | Usage | Metabolites | Physiological aspects | Bone tumors | Diagnosis | Nuclear magnetic resonance | Biological markers | Giant cell tumors | Health aspects | Identification and classification
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2013, Volume 45, Issue 12, pp. 1479 - 1482
Journal Article