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Rheumatology, ISSN 1462-0324, 04/2018, Volume 57, Issue suppl_3
Journal Article
Rheumatology, ISSN 1462-0324, 04/2018, Volume 57, Issue suppl_3
Journal Article
2001, Milestones in drug therapy., ISBN 3764360593, x, 205
Book
Nature, ISSN 0028-0836, 08/2011, Volume 476, Issue 7361, pp. 458 - 462
Glucocorticoids are released in response to stressful experiences and serve many beneficial homeostatic functions. However, dysregulation of glucocorticoids is... 
ANTIDEPRESSANTS | FOREBRAIN | GLUCOCORTICOID-RECEPTOR | MULTIDISCIPLINARY SCIENCES | NEURONS | RATS | ANIMAL-MODEL | ASTROCYTES | LESIONS | BRAIN | TRANSGENIC MICE | Depression - physiopathology | Male | Receptors, Glucocorticoid - metabolism | Hippocampus - drug effects | Receptors, Glucocorticoid - analysis | Depression - drug therapy | Dexamethasone - pharmacology | Dentate Gyrus - drug effects | Glucocorticoids - metabolism | Neurogenesis - radiation effects | Behavior, Animal - drug effects | Neurogenesis - drug effects | Stress, Physiological - drug effects | Swimming | Hypothalamo-Hypophyseal System - physiology | Corticosterone - secretion | Pituitary-Adrenal System - physiology | Glucocorticoids - secretion | Stress, Physiological - physiology | Hypothalamo-Hypophyseal System - drug effects | Restraint, Physical - psychology | Pituitary-Adrenal System - drug effects | Mice, Inbred C57BL | Restraint, Physical - physiology | Behavior, Animal - physiology | Mice, Transgenic | Hippocampus - cytology | Dentate Gyrus - cytology | Animals | Dentate Gyrus - physiology | Neurogenesis - physiology | Glucocorticoids - pharmacology | Corticosterone - metabolism | Mice | Hippocampus - physiology | Corticosterone - analysis | Murders & murder attempts | Antidepressants | Rodents | Histology | Behavior | Kinases | Laboratory animals | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2009, Volume 284, Issue 38, pp. 25593 - 25601
Glucocorticoids are important regulators of lipid homeostasis, and chronically elevated glucocorticoid levels induce hypertriglyceridemia, hepatic steatosis,... 
OBESITY | PLASMA | GENE | CHROMATIN | ANGIOGENESIS | DIET | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYPERLIPIDEMIA | MICE | TRANSCRIPTIONAL REGULATION | PROTEIN-4 | Transcription, Genetic - drug effects | Hypertriglyceridemia - genetics | Humans | Dexamethasone - adverse effects | Receptors, Glucocorticoid - metabolism | Hepatocytes - metabolism | Fatty Liver - chemically induced | Adipose Tissue - metabolism | Angiopoietin-like 4 Protein | Dexamethasone - pharmacology | Glucocorticoids - genetics | Glucocorticoids - metabolism | Response Elements - genetics | Lipoprotein Lipase - metabolism | Glucocorticoids - adverse effects | Fatty Liver - genetics | Angiopoietins - metabolism | Fatty Liver - metabolism | Lipoprotein Lipase - genetics | Liver - metabolism | Rats | Hypertriglyceridemia - metabolism | Mice, Knockout | Triglycerides - metabolism | Adipose Tissue, White | Hypertriglyceridemia - chemically induced | Animals | Receptors, Glucocorticoid - genetics | Cell Line, Tumor | Dexamethasone - metabolism | Glucocorticoids - pharmacology | Mice | Transcription, Genetic - genetics | Triglycerides - genetics | Angiopoietins - genetics | Index Medicus | Lipids and Lipoproteins | Metabolism, Regulation, and Signaling | Transcription | Dermatologi och venereologi | Dermatology and Venereal Diseases | Dexamethasone/adverse effects/metabolism/pharmacology | Hypertriglyceridemia/chemically induced/genetics/metabolism | Receptors | Adipose Tissue/metabolism | Liver/metabolism | Tumor | Adipose Tissue | Cell Line | Fatty Liver/chemically induced/genetics/metabolism | Triglycerides/genetics/ metabolism | Response Elements/genetics | Angiopoietins/genetics/ metabolism | Knockout | Lipoprotein Lipase/genetics/metabolism | White | Hepatocytes/metabolism | Genetic/drug effects/genetics | Glucocorticoids/adverse effects/genetics/ metabolism/pharmacology | Glucocorticoid/genetics/ metabolism
Journal Article
PLoS Biology, ISSN 1544-9173, 10/2015, Volume 13, Issue 10, pp. 1 - 16
Sepsis, an exaggerated systemic inflammatory response, remains a major medical challenge. Both hyperinflammation and immunosuppression are implicated as causes... 
NK CELLS | TUMOR NECROSIS FACTOR | IFN-GAMMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | ENDOTOXIN TOLERANCE | GAMMA-INTERFERON | BIOLOGY | SEPTIC SHOCK | RECEPTOR | MICE | T-CELLS | Antibodies, Neutralizing - administration & dosage | Receptors, Glucocorticoid - antagonists & inhibitors | Spleen - immunology | Dendritic Cells - immunology | Dendritic Cells - pathology | Male | Shock, Septic - prevention & control | Receptors, Glucocorticoid - metabolism | Spleen - drug effects | Shock, Septic - immunology | Shock, Septic - metabolism | Receptors, Glucocorticoid - agonists | CD11c Antigen - metabolism | Dose-Response Relationship, Drug | Interleukin-12 - blood | CD11c Antigen - genetics | Glucocorticoids - metabolism | Antibodies, Neutralizing - therapeutic use | Interleukin-12 - antagonists & inhibitors | Dendritic Cells - drug effects | Female | Spleen - pathology | Dendritic Cells - metabolism | Shock, Septic - pathology | Lipopolysaccharides - toxicity | Specific Pathogen-Free Organisms | Immunity, Innate - drug effects | Mice, Inbred C57BL | Cells, Cultured | Glucocorticoids - blood | Mice, Transgenic | Interleukin-12 - metabolism | Mice, Knockout | Animals | Glucocorticoids - antagonists & inhibitors | Signal Transduction - drug effects | Spleen - metabolism | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Receptors, Glucocorticoid - genetics | Glucocorticoids - agonists | Crosses, Genetic | Index Medicus | Medical research | Flow cytometry | Statistical analysis | Cytokines | Dendritic cells | Rodents | Mortality | Sepsis | Software | Inflammation | Experiments
Journal Article
Rheumatology, ISSN 1462-0324, 04/2018, Volume 57, Issue suppl_3
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2013, Volume 110, Issue 42, pp. 17035 - 17040
Journal Article
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2017, Volume 76, Issue Suppl 2, p. 609
BackgroundGCA may be an interleukin-6 (IL-6) driven disease and IL-6 blockade is emerging as an exciting therapy of IL-6.1 We measured serial IL-6 levels in... 
Glucocorticoids | Biomarkers
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2017, Volume 76, Issue Suppl 2, p. 723
BackgroundResistant – recurring pericarditis (RRP) is often associated with autoinflammatory syndromes. Conventional therapy with glucocorticoids and... 
Glucocorticoids | Mutation
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2017, Volume 76, Issue Suppl 2, p. 745
BackgroundThe minimal invasive ultrasound-guided synovial biopsy (USG-SB) method has been shown to be safe and tolerable. The method has accelerated the... 
Glucocorticoids | Biomarkers
Journal Article
by Chen, X and Zeng, H
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2017, Volume 76, Issue Suppl 2, p. 797
ObjectivesMacrophage activation syndrome (MAS) is a severe, potentially life-threatening syndrome.Here we aim to review the precipitating events,clinical... 
Glucocorticoids | Macrophages
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2017, Volume 76, Issue Suppl 2, p. 820
ObjectivesThe objective is to study association of genotypes for Bcl1 polymorphism in the glucocorticoid receptor (GR) gene with ischemic heart disease (IHD)... 
Glucocorticoids | Genotypes
Journal Article
2006, Handbook of experimental pharmacology, ISBN 9783540258759, Volume 172, viii, 442
Molecular chaperones are involved in a wide variety of essential cellular processes in living cells. A subset of molecular chaperones have been initially... 
Molecular chaperones | Physiological effect | Proteins | Medical Biochemistry | Biomedicine | Pharmacology/Toxicology | Cell Biology
Book
JOURNAL OF PEDIATRICS, ISSN 0022-3476, 08/2016, Volume 175, pp. 243 - 243
Journal Article
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