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gp91phox (126) 126
nadph oxidase (84) 84
animals (69) 69
humans (69) 69
nadph oxidase 2 (69) 69
index medicus (63) 63
nadph oxidases - metabolism (63) 63
nadph oxidases - genetics (55) 55
gp91 (47) 47
membrane glycoproteins - genetics (47) 47
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oxidative stress (42) 42
reactive oxygen species (41) 41
nadh oxidase (39) 39
reactive oxygen species - metabolism (39) 39
superoxide (36) 36
male (35) 35
biochemistry & molecular biology (34) 34
membrane glycoproteins - metabolism (34) 34
oxidases (32) 32
superoxides - metabolism (26) 26
mice, inbred c57bl (23) 23
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activation (22) 22
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chronic granulomatous disease (21) 21
expression (20) 20
immunology (19) 19
angiotensin-ii (18) 18
cells, cultured (17) 17
nox2 (17) 17
article (16) 16
reactive oxygen (16) 16
chronic granulomatous-disease (15) 15
molecular sequence data (15) 15
granulomatous disease, chronic - genetics (14) 14
inflammation (14) 14
nadph oxidases - deficiency (14) 14
neurosciences (14) 14
nox1 (14) 14
proteins (14) 14
base sequence (13) 13
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hematology (12) 12
membrane glycoproteins - deficiency (12) 12
neutrophils (12) 12
peripheral vascular disease (12) 12
pharmacology & pharmacy (12) 12
rats (12) 12
amino acid sequence (11) 11
atherosclerosis (11) 11
cell biology (11) 11
nadph oxidases - antagonists & inhibitors (11) 11
p22phox (11) 11
physiology (11) 11
rna, messenger - metabolism (11) 11
gp91 phox (10) 10
gp91phox-containing nadph oxidase (10) 10
microglia (10) 10
mutation (10) 10
nadph oxidases - chemistry (10) 10
oxidase (10) 10
phosphoproteins - genetics (10) 10
phosphoproteins - metabolism (10) 10
respiratory burst (10) 10
ros (10) 10
smooth-muscle-cells (10) 10
analysis (9) 9
apoptosis (9) 9
biophysics (9) 9
disease models, animal (9) 9
endothelial-cells (9) 9
gene expression (9) 9
hydrogen-peroxide (9) 9
hypertension (9) 9
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life sciences (9) 9
nadph oxidase 1 (9) 9
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niacinamide (9) 9
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nox4 (9) 9
phosphates (9) 9
cardiac & cardiovascular systems (8) 8
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neutrophils - metabolism (8) 8
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phagocytes (8) 8
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blotting, western (7) 7
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endothelial dysfunction (7) 7
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Mechanisms for suppressing NADPH oxidase in the vascular wall, 12/2005
Oxidative stress underlies many forms of vascular disease as well as tissue injury following ischemia and reperfusion. The major source of oxidative stress in... 
atherosclerosis - gp91phox - hypertension - NADPH oxidase - nitric oxide - Nox1 - Nox4 - reactive oxygen species
Journal
The Journal of allergy and clinical immunology, ISSN 0091-6749, 2/2019, Volume 143, Issue 2, pp. 782 - 785.e1
We demonstrate for the first time that EROS (CYBC1/C17ORF62) regulates abundance of the gp91phox-p22phox heterodimer of the phagocyte NADPH oxidase in human... 
EROS | Chronic granulomatous disease | CYBC1 | C17ORF62 | gp91phox | Nox2
Journal Article
Experimental Neurology, ISSN 0014-4886, 10/2018, Volume 308, pp. 111 - 119
Parkinson's disease (PD), the second most common age-related progressive neurodegenerative disorder, is characterized by dopamine depletion and the loss of... 
Nav1.6 | Parkinson's disease | TNF-α | Neuroinflammation | MPTP | gp91phox | Voltage-gated sodium channels | Zonisamide | Microglia | Index Medicus
Journal Article
Cutaneous and Ocular Toxicology, ISSN 1556-9527, 10/2019, Volume 38, Issue 4, pp. 349 - 355
Purpose: We have previously reported that skin barrier function is disrupted in mice with colonic tumours induced by azoxymethane (AOM) and dextran sodium... 
Skin barrier | TSLP | ROS | NLRP3 | Gp91phox | colonic tumours | superoxide anion
Journal Article
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 06/2012, Volume 302, Issue 11, pp. L1209 - L1220
Emin MT, Sun L, Huertas A, Das S, Bhattacharya J, Bhattacharya S. Platelets induce endothelial tissue factor expression in a mouse model of acid-induced lung... 
CD41 | gp91phox - | Reactive oxygen species | P-selectin | Von Willebrand factor | PHYSIOLOGY | gp91phox- | PERMEABILITY | THROMBOSIS | TIDAL VOLUME VENTILATION | VENULAR CAPILLARIES | MECHANISMS | ASPIRATION | PRESSURE | RESPIRATORY SYSTEM | von Willebrand factor | reactive oxygen species | DISEASE | COAGULATION | MICE | Blood Platelets - immunology | Hydrochloric Acid - adverse effects | Reactive Oxygen Species - metabolism | Membrane Glycoproteins - metabolism | Antigens, CD - biosynthesis | P-Selectin - metabolism | Platelet Membrane Glycoprotein IIb - biosynthesis | Leukocyte Common Antigens - biosynthesis | NADPH Oxidases - metabolism | Hydrochloric Acid - toxicity | von Willebrand Factor - biosynthesis | Cadherins - biosynthesis | Acute Lung Injury - blood | Platelet Glycoprotein GPIb-IX Complex - biosynthesis | Blood Coagulation | NADPH Oxidases - genetics | Thromboplastin - biosynthesis | Disease Models, Animal | von Willebrand Factor - metabolism | Lung - pathology | Endothelial Cells - metabolism | Mice, Inbred C57BL | Mice, Transgenic | NADPH Oxidase 2 | Membrane Glycoproteins - genetics | Animals | Acute Lung Injury - chemically induced | Blood Platelets - metabolism | Endothelium, Vascular - metabolism | P-Selectin - biosynthesis | Mice | Platelet Activation - drug effects | Thromboplastin - metabolism | Platelet Aggregation Inhibitors - immunology | Lung - immunology | Endothelial Cells - drug effects | Blood platelets | Lung diseases | Physiological aspects | Development and progression | Genetic aspects | Research | Gene expression | Health aspects | Endothelium | gp91phox
Journal Article
NEUROPHARMACOLOGY, ISSN 0028-3908, 12/2018, Volume 143, pp. 176 - 185
Phosphodiesterase 2 (PDE2) plays an important role in treatment of stress-related depression through regulation of antioxidant defense and neuroprotective... 
Oxidative stress | ANTIDEPRESSANT | Phosphodiesterase 2 | INVOLVEMENT | Depression | NEUROSCIENCES | IN-VITRO | Bay 60-7550 | PHARMACOLOGY & PHARMACY | Anxiety | gp91phox | NADPH OXIDASES | BRAIN
Journal Article
FASEB Journal, ISSN 0892-6638, 03/2007, Volume 21, Issue 3, pp. 927 - 934
Journal Article
Journal Article
Journal of Biochemistry, ISSN 0021-924X, 06/2018, Volume 163, Issue 6, pp. 489 - 501
Nox4, a member of the NADPH-and oxygen-dependent oxidoreductases that generate reactive oxygen species (ROS), is widely expressed and constitutively active. To... 
reactive oxygen | redox regulation | electron transfer | NADPH oxidase | flavocytochrome | GP91PHOX | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYTOCHROME | CYSTEINE | MESSENGER | NAD(P)H OXIDASE | NOX4 | REDOX | EXPRESSION | REVEALS
Journal Article
Free radical biology & medicine, ISSN 0891-5849, 1/2012, Volume 52, Issue 2, pp. 303 - 313
Rotenone, a widely used pesticide, reproduces Parkinsonism in rodents and associates with increased risk for Parkinson’s disease. We previously reported... 
macrophages | PHOX | NADPH oxidase | rotenone | Rac1 | gp91phox | superoxide | NOX2
Journal Article
by Lee, WJ and Ham, SA and Yoo, H and Hwang, JS and Yoo, T and Paek, KS and Lim, DS and Han, SG and Lee, CH and Hong, K and Seo, HG
JOURNAL OF CELLULAR BIOCHEMISTRY, ISSN 0730-2312, 07/2018, Volume 119, Issue 7, pp. 5609 - 5619
Neuroinflammation-associated release of glutamate from activated microglia has been implicated in the progression of neurodegenerative diseases. However, the... 
BETA/DELTA AGONIST | NADPH OXIDASE | OXIDATIVE STRESS | STAT1 | DELTA | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEURODEGENERATION | LPS | CELL BIOLOGY | SOCS1 | PPAR | INFLAMMATION | ROS | MOUSE MODEL | CENTRAL-NERVOUS-SYSTEM | gp91phox | JAK2 | microglial cells | MEDIATED INHIBITION | EXPRESSION
Journal Article