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Cell (Cambridge), ISSN 0092-8674, 04/2017, Volume 169, Issue 3, pp. 422 - 430.e10
K+ channel | drug-induced Long QT | hERG | voltage-dependent gating | inactivation | hERG block | cryo-EM | structure | channel | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cryoelectron Microscopy | Amino Acid Sequence | Sequence Alignment | ERG1 Potassium Channel - ultrastructure | ERG1 Potassium Channel - chemistry | Humans | Models, Molecular | Protein Conformation | ERG1 Potassium Channel - isolation & purification | ERG1 Potassium Channel - metabolism | Index Medicus
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European journal of medicinal chemistry, ISSN 0223-5234, 2020, pp. 113033 - 113033
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British journal of pharmacology, ISSN 0007-1188, 09/2011, Volume 164, Issue 2b, pp. 419 - 432
KCNH2 | safety assessment | drug sensitivity | hERG | torsades de pointes | hERG 1a | hERG 1b | arrhythmia | hERG blockers | Kv11.1 | 11.1 | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Drug Evaluation, Preclinical - methods | Fluoxetine - pharmacology | Protein Subunits | Arrhythmias, Cardiac - chemically induced | Humans | Torsades de Pointes - chemically induced | Torsades de Pointes - genetics | Long QT Syndrome - chemically induced | Ether-A-Go-Go Potassium Channels - genetics | Ether-A-Go-Go Potassium Channels - antagonists & inhibitors | Piperidines - pharmacology | Sensitivity and Specificity | HEK293 Cells | Inhibitory Concentration 50 | Long QT Syndrome - genetics | Pyridines - pharmacology | Action Potentials - drug effects | Arrhythmias, Cardiac - genetics | Cell Line, Transformed | Index Medicus | Research Papers
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ACS medicinal chemistry letters, ISSN 1948-5875, 12/2015, Volume 6, Issue 12, pp. 1241 - 1246
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ACS medicinal chemistry letters, ISSN 1948-5875, 10/2018, Volume 9, Issue 10, pp. 1039 - 1044
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Biochemical pharmacology, ISSN 0006-2952, 08/2016, Volume 113, pp. 24 - 35
Antiarrhythmic | IKr | QT interval | hERG | Amiodarone | Long QT | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Amino Acid Sequence | Action Potentials - genetics | Anti-Arrhythmia Agents - pharmacology | Humans | Dose-Response Relationship, Drug | Patch-Clamp Techniques | Transfection | Alanine - genetics | Mutagenesis | HEK293 Cells | Protein Binding | ERG1 Potassium Channel - genetics | Molecular Docking Simulation | ERG1 Potassium Channel - antagonists & inhibitors | Mutation | Action Potentials - drug effects | Amiodarone - pharmacology | Potassium channels | Index Medicus | IC50, half-maximal inhibitory concentration | IKs, slow delayed rectifier potassium current | diLQTS, drug induced long QT syndrome | hERG, human-Ether-à-go-go-Related Gene | HEK, human embryonic kidney | IKr, rapid delayed rectifier potassium current | LQTS, long QT syndrome | DEA, desethylamiodarone | AF, atrial fibrillation | IhERG, ionic current carried by hERG potassium channels | I Kr
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ACS medicinal chemistry letters, ISSN 1948-5875, 10/2017, Volume 8, Issue 10, pp. 1019 - 1024
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Journal of veterinary pharmacology and therapeutics, ISSN 0140-7783, 08/2018, Volume 41, Issue 4, pp. 536 - 545
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The Journal of physiology, ISSN 0022-3751, 10/2018, Volume 596, Issue 19, pp. 4629 - 4650
hERG channel | FRET | deactivation | Neurosciences | Physiology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Deactivation | HERG protein | Ligands | Homology | Potassium channels (voltage-gated) | Fluorescence resonance energy transfer | Mutation | Index Medicus | Molecular and Cellular | Research Paper
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Design, synthesis and evaluation of benzothiazole derivatives as multifunctional agents
Bioorganic chemistry, ISSN 0045-2068, 08/2020, Volume 101, pp. 103960 - 103960
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European journal of pharmacology, 12/2020, Volume 893, pp. 173813 - 173813
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Journal of pharmacological sciences, ISSN 1347-8613, 2009, Volume 109, Issue 1, pp. 152 - 156
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Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 01/2021, Volume 31, pp. 127663 - 127663
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European journal of medicinal chemistry, ISSN 0223-5234, 01/2021, Volume 209, pp. 112914 - 112914
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Pharmacological research, ISSN 1043-6618, 2008, Volume 57, Issue 3, pp. 181 - 195
QT interval | HERG K + channels | Arrhythmia | Drug development | Torsades de pointes | HERG K | channels | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Ether-A-Go-Go Potassium Channels - antagonists & inhibitors | Arrhythmias, Cardiac - drug therapy | Animals | Ether-A-Go-Go Potassium Channels - drug effects | Humans | Potassium Channel Blockers - therapeutic use | Ether-A-Go-Go Potassium Channels - physiology | Long QT Syndrome - drug therapy | Torsades de Pointes - drug therapy | Arrhythmias, Cardiac - physiopathology | Potassium Channel Blockers - pharmacology | Neoplasms - drug therapy | Index Medicus
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