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1. Full Text Atypical hemolytic uremic syndrome
by Loirat, Chantal and Frémeaux-Bacchi, Véronique
Orphanet Journal of Rare Diseases, ISSN 1750-1172, 2011, Volume 6, Issue 1, pp. 60 - 60
Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia, thrombocytopenia and renal impairment. Atypical HUS (aHUS) defines non... 
Plasma exchange | Factor H | Combined liver-kidney transplantation | Plasma infusion | Factor B | Atypical hemolytic uremic syndrome | Eculizumab | Membrane cofactor protein | Thrombomodulin | Factor I | Kidney transplantation | MEDICINE, RESEARCH & EXPERIMENTAL | factor I | CFHR1/CFHR3 DEFICIENCY | LIVER-KIDNEY TRANSPLANTATION | plasma infusion | kidney transplantation | eculizumab | factor B | THROMBOTIC THROMBOCYTOPENIC PURPURA | SUCCESSFUL RENAL-TRANSPLANTATION | factor H | combined liver-kidney transplantation | INHIBITOR ECULIZUMAB | ALTERNATIVE PATHWAY | membrane cofactor protein | thrombomodulin | GENETICS & HEREDITY | plasma exchange | SUCCESSFUL PLASMA THERAPY | FACTOR-I MUTATIONS | COMPLEMENT-FACTOR-H | Complement Activation | Humans | Middle Aged | Child, Preschool | Complement System Proteins - immunology | Infant | Male | Hemolytic-Uremic Syndrome - epidemiology | Young Adult | Hemolytic-Uremic Syndrome - genetics | Hemolytic-Uremic Syndrome - physiopathology | Aged, 80 and over | Adult | Complement System Proteins - genetics | Female | Hemolytic-Uremic Syndrome - therapy | Child | Infant, Newborn | Risk Factors | Kidney Transplantation | Animals | Adolescent | Aged | Mice | Mutation | Atypical Hemolytic Uremic Syndrome | Viral antibodies | Usage | Care and treatment | Antibodies | Genetic aspects | Research | Diagnosis | Health aspects | Genetic screening | Hemolytic-uremic syndrome | Risk factors | Lupus | Plasma | E coli | Disease | Vascular endothelial growth factor | Streptococcus infections
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2. Full Text Atypical Hemolytic Uremic Syndrome
by Kavanagh, David, MD, PhD and Goodship, Tim H., MD and Richards, Anna, MD, PhD
Seminars in Nephrology, ISSN 0270-9295, 2013, Volume 33, Issue 6, pp. 508 - 530
Summary Hemolytic uremic syndrome (HUS) is a triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. The atypical form of HUS is... 
Nephrology | factor I | membrane cofactor protein | thrombomodulin | transplantation | Complement | eculizumab | factor H | hemolytic uremic syndrome | Factor H | Hemolytic uremic syndrome | Eculizumab | Membrane cofactor protein | Transplantation | Thrombomodulin | Factor I | C-REACTIVE PROTEIN | LIVER-KIDNEY TRANSPLANTATION | BONE-MARROW-TRANSPLANTATION | CLINICAL CHARACTERISTICS | RENAL-TRANSPLANTATION | THROMBOTIC THROMBOCYTOPENIC PURPURA | FACTOR-I | ENDOTHELIAL-CELLS | UROLOGY & NEPHROLOGY | COMPLEMENT-FACTOR-H
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3. Full Text Hemolytic uremic syndrome
by Mele, Caterina and Remuzzi, Giuseppe and Noris, Marina
Seminars in Immunopathology, ISSN 1863-2297, 7/2014, Volume 36, Issue 4, pp. 399 - 420
Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy defined by thrombocytopenia, nonimmune microangiopathic hemolytic anemia, and acute renal... 
Biomedicine | Immunology | Complement system activation | aHUS | Eculizumab | Internal Medicine | STEC-HUS | Pneumococcal-HUS | THOMSEN-FRIEDENREICH ANTIGEN | OF-FUNCTION MUTATION | LIVER-KIDNEY TRANSPLANTATION | ESCHERICHIA-COLI O157-H7 | THROMBOTIC THROMBOCYTOPENIC PURPURA | SHIGA-TOXIN | IMMUNOLOGY | PATHOLOGY | VON-WILLEBRAND-FACTOR | THERAPEUTIC PLASMA-EXCHANGE | MEMBRANE COFACTOR PROTEIN | COMPLEMENT-FACTOR-H | Hemolytic-Uremic Syndrome - pathology | Pneumococcal Infections - epidemiology | Pneumococcal Infections - immunology | Humans | Pneumococcal Infections - pathology | Complement System Proteins - immunology | Complement Activation - immunology | Hemolytic-Uremic Syndrome - immunology | Hemolytic-Uremic Syndrome - epidemiology | Streptococcus pneumoniae - immunology | Bacteria | Pneumonia | Anemia | Bacterial pneumonia
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4. Full Text Hemolytic uremic syndrome
by Noris, Marina and Remuzzi, Giuseppe
Journal of the American Society of Nephrology, ISSN 1046-6673, 2005, Volume 16, Issue 4, pp. 1035 - 1050
THROMBOTIC-THROMBOCYTOPENIC PURPURA | COFACTOR PROTEIN CD46 | SHIGELLA-DYSENTERIAE SEROTYPE-1 | COMPLEMENT FACTOR-H | ESCHERICHIA-COLI O157-H7 | PROGNOSTIC-FACTORS | UROLOGY & NEPHROLOGY | MICROVASCULAR ENDOTHELIAL-CELLS | THERAPEUTIC PLASMA-EXCHANGE | SHIGA-LIKE TOXINS | RENAL-TRANSPLANTATION | Hemolytic-Uremic Syndrome - genetics | Hemolytic-Uremic Syndrome - etiology | Phenotype | Humans | Europe - epidemiology | Hemolytic-Uremic Syndrome - therapy | North America - epidemiology | Hemolytic-Uremic Syndrome - epidemiology | Shiga Toxins | Incidence
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5. Full Text Atypical Hemolytic–Uremic Syndrome
by Noris, Marina and Remuzzi, Giuseppe
The New England Journal of Medicine, ISSN 0028-4793, 10/2009, Volume 361, Issue 17, pp. 1676 - 1687
The hemolytic–uremic syndrome, which is characterized by nonimmune hemolytic anemia, thrombocytopenia, and renal impairment, occurs most frequently in young... 
Complement Factor H - immunology | Autoantibodies - metabolism | Prognosis | Humans | Penetrance | Kidney Transplantation | Kidney Glomerulus - pathology | Hemolytic-Uremic Syndrome - classification | Complement System Proteins - metabolism | Hemolytic-Uremic Syndrome - genetics | Point Mutation | Complement System Proteins - genetics | Hemolytic-Uremic Syndrome - therapy | Complement Pathway, Alternative - genetics | Mutation | Complement Factor H - genetics | Care and treatment | Hemolytic-uremic syndrome | Diagnosis
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6. Hemolytic Uremic Syndrome
by Cody, Ellen M and Dixon, Bradley P
Pediatric Clinics of North America, ISSN 0031-3955, 02/2019, Volume 66, Issue 1, pp. 235 - 246
Hemolytic uremic syndrome (HUS) is the clinical triad of thrombocytopenia, anemia, and acute kidney injury. Classically associated with enterocolitis from... 
Pneumococcal HUS | Cobalamin C | Atypical HUS | Hemolytic uremic syndrome | Shiga toxin | Escherichia coli | ACTIVATION | DIARRHEA | FUNCTIONAL TESTS | COMPLEMENT INHIBITOR ECULIZUMAB | ESCHERICHIA-COLI | RISK | RELATIVE NEPHROPROTECTION | PEDIATRIC-PATIENTS | NEUROLOGICAL INVOLVEMENT | PEDIATRICS | ANTIBIOTIC-TREATMENT | Fluid Therapy | Diagnosis, Differential | Hemolytic-Uremic Syndrome - etiology | Antibodies, Monoclonal, Humanized - therapeutic use | Prognosis | Erythrocyte Transfusion | Humans | Risk Factors | Kidney Transplantation | Plasma Exchange | Hemolytic-Uremic Syndrome - therapy | Hemolytic-Uremic Syndrome - diagnosis | Streptococcal Infections - complications | Escherichia coli Infections - complications | Renal Dialysis
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7. Full Text Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic Syndrome
by Legendre, C.M and Licht, C and Muus, P and Greenbaum, L.A and Babu, S and Bedrosian, C and Bingham, C and Cohen, D.J and Delmas, Y and Douglas, K and Eitner, F and Feldkamp, T and Fouque, D and Furman, R.R and Gaber, O and Herthelius, M and Hourmant, M and Karpman, D and Lebranchu, Y and Mariat, C and Menne, J and Moulin, B and Nürnberger, J and Ogawa, M and Remuzzi, G and Richard, T and Sberro-Soussan, R and Severino, B and Sheerin, N.S and Trivelli, A and Zimmerhackl, L.B and Goodship, T and Loirat, C and Paediatrics (Lund) and Pediatric Nephrology and Lund University and Lunds universitet and Pediatrik, Lund and Pediatrisk nefrologi
The New England Journal of Medicine, ISSN 0028-4793, 06/2013, Volume 368, Issue 23, pp. 2169 - 2181
This article describes the use of eculizumab in patients with atypical hemolytic–uremic syndrome. This C5 inhibitor was associated with improvement in... 
MEDICINE, GENERAL & INTERNAL | IMPACT | PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA | INSIGHTS | Humans | Middle Aged | Hemolytic-Uremic Syndrome - blood | Male | Plasma Exchange | Young Adult | Hemolytic-Uremic Syndrome - genetics | Antibodies, Monoclonal, Humanized - pharmacokinetics | Antibodies, Monoclonal, Humanized - blood | Adult | Female | Hemolytic-Uremic Syndrome - therapy | Antibodies, Monoclonal, Humanized - adverse effects | Antibodies, Monoclonal, Humanized - therapeutic use | Kidney Diseases - drug therapy | Combined Modality Therapy | Thrombotic Microangiopathies - prevention & control | Platelet Count | Adolescent | Quality of Life | Aged | Kidney Diseases - etiology | Mutation | Complement C5 - antagonists & inhibitors | Hemolytic-Uremic Syndrome - drug therapy | Plasma | Adolescence | Thrombotic microangiopathy | Renal function | Complement inhibitors | Toxicity | Mortality | Clinical trials | Complement | Glomerular filtration rate | Defects | Quality of life | Studies | Platelets | Index Medicus | Abridged Index Medicus | Clinical Medicine | Pediatrics | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Pediatrik
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8. Full Text Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome
by Lemaire, Mathieu and Frémeaux-Bacchi, Véronique and Schaefer, Franz and Choi, Murim and Tang, Wai Ho and Quintrec, Moglie Le and Fakhouri, Fadi and Taque, Sophie and Nobili, François and Martinez, Frank and Ji, Weizhen and Overton, John D and Mane, Shrikant M and Nürnberg, Gudrun and Altmüller, Janine and Thiele, Holger and Morin, Denis and Deschenes, Georges and Baudouin, Véronique and Llanas, Brigitte and Collard, Laure and Majid, Mohammed A and Simkova, Eva and Nürnberg, Peter and Rioux-Leclerc, Nathalie and Moeckel, Gilbert W and Gubler, Marie Claire and Hwa, John and Loirat, Chantal and Lifton, Richard P
Nature Genetics, ISSN 1061-4036, 05/2013, Volume 45, Issue 5, pp. 531 - 536
Pathologic thrombosis is a major cause of mortality. Hemolytic-uremic syndrome (HUS) features episodes of small-vessel thrombosis resulting in microangiopathic... 
PROTEIN-KINASE-C | ACTIVATION | HUMAN-PLATELETS | GENETICS & HEREDITY | MICROANGIOPATHY | VASCULAR ENDOTHELIAL-CELLS | DIACYLGLYCEROL KINASES | INHIBITOR | ASSOCIATION | EXPRESSION | EPSILON | Hemolytic-Uremic Syndrome - etiology | Renal Insufficiency, Chronic | Genes, Recessive - genetics | Humans | Child, Preschool | Molecular Sequence Data | Infant | Male | Acute Kidney Injury - genetics | Mutation - genetics | Diacylglycerol Kinase - genetics | Immunoenzyme Techniques | Thrombotic Microangiopathies - genetics | Hemolytic-Uremic Syndrome - pathology | Thrombocytopenia - genetics | Exome - genetics | Female | Atypical Hemolytic Uremic Syndrome | Child | Care and treatment | Gene mutations | Von Willebrand factor | Genetic aspects | Research | Health aspects | Hemolytic-uremic syndrome | Risk factors | Proteins | Studies | Confidence intervals | Pediatrics | Genealogy | Genetics | Amino acids | Genomes | Mutation | Age | Data bases | Siblings | Life Sciences
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