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Chemical Communications, ISSN 1359-7345, 04/2014, Volume 50, Issue 33, pp. 4331 - 4334
A practical and efficient Rh(III)-catalyzed aerobic C-H activation has been developed for the facile synthesis of a broad range of indoles from simple anilines... 
FUNCTIONALIZATION | HAPALINDOLES | ACETANILIDES | ACTIVATION | AMINATION | ANNULATION | EFFICIENT SYNTHESIS | POTASSIUM | BOND | CHEMISTRY, MULTIDISCIPLINARY | CYCLIZATION | Oxygen | Sole | Oxidants | Aniline | Oxidizing agents | Activation | Indoles | Alkynes
Journal Article
Tetrahedron, ISSN 0040-4020, 06/2015, Volume 71, Issue 22, pp. 3652 - 3665
The family of cyanobacteria produces a class of biogenetically related indole natural products that include hapalindoles and ambiguines. In this full account,... 
Alkaloid | Terpene | Protecting-group-free | Indole | Total synthesis | FISCHERELLA | NATURAL-PRODUCTS | CHEMISTRY, ORGANIC | CARBONYL-COMPOUNDS | WELWISTATIN | ENANTIOSPECIFIC TOTAL-SYNTHESIS | METHYLWELWITINDOLINONE-C ISOTHIOCYANATE | MARINE ALKALOIDS HAPALINDOLES | CONSTRUCTION | INDOLE ALKALOIDS | OXIDIZED WELWITINDOLINONES | Synthesis | Organic compounds
Journal Article
ANTICANCER RESEARCH, ISSN 0250-7005, 06/2018, Volume 38, Issue 6, pp. 3299 - 3307
Background: Prostate cancer presents the highest incidence rates among all cancers in men. Hapalindole H (Hap H), isolated from Fischerella muscicola (UTEX... 
CYTOKINES | mitochondria | AMBIGUINE | apoptosis | INDUCTION | hapalindole H | ONCOLOGY | inflammation | E-SELECTIN | GENES | cancer | Prostate | EXPRESSION | prostate
Journal Article
by Zhu, Q and Liu, XY
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, ISSN 1860-5397, 06/2017, Volume 13, pp. 1168 - 1173
The in vitro biochemical characterization revealed that iron/2-oxoglutarate (Fe/2OG)-dependent aliphatic halogenase WelO5* in Hapalosiphon welwitschii IC-52-3... 
biosynthetic divergency | C-H activation | halogenase | HAPALINDOLE | non-heme iron enzyme | AMBIGUINE | CHEMISTRY, ORGANIC | alkaloid biogenesis | BOND | DISCOVERY | MOLECULES | FAMILY
Journal Article
Angewandte Chemie - International Edition, ISSN 1433-7851, 05/2016, Volume 55, Issue 19, pp. 5780 - 5784
The elucidation of enigmatic enzymatic chlorination timing in ambiguine indole alkaloid biogenesis led to the discovery and characterization of AmbO5 protein... 
non-heme iron enzyme | C-H activation | halogenase | evolution | alkaloid biogenesis | SYRB2 | IDENTIFICATION | CHEMISTRY, MULTIDISCIPLINARY | HAPALOSIPHON-WELWITSCHII | BIOSYNTHESIS | HAPALINDOLE | INTERMEDIATE | GENERATION | CHLORINATION | Enzymes | Alkaloids | Biosynthesis | Catalysis | Heme | Index Medicus
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 12/2006, Volume 71, Issue 26, pp. 9865 - 9868
Journal Article
Organic Letters, ISSN 1523-7060, 12/2016, Volume 18, Issue 24, pp. 6392 - 6395
Biomimetic total synthesis of (-)-mycoleptodiscin A (1) was achieved starting from the enantiopure key intermediate, which was prepared by Friedel-Crafts... 
HAPALINDOLES | CHEMISTRY, ORGANIC | PROTECTING GROUPS | INDOLOSESQUITERPENE | ALKALOIDS
Journal Article
Organic Letters, ISSN 1523-7060, 02/2018, Volume 20, Issue 3, pp. 632 - 635
The first enantioselective total synthesis of (-)-petromindole, an architecturally distinct congener of indole diterpene family, has been achieved. Key... 
TREMORGENIC INDOLE ALKALOIDS | (+)-PASPALICINE | ABSOLUTE-CONFIGURATION | HAPALINDOLE | CHEMISTRY, ORGANIC | 2ND-GENERATION SYNTHESIS | DITERPENE
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 03/2019, Volume 141, Issue 12, pp. 4820 - 4823
Described is a concise total synthesis of (-)-ambiguine P, a cycloheptane-containing member of the hapalindole alkaloids. The challenging pentacyclic framework... 
HAPALINDOLES | AMBIGUINE ISONITRILES | CHEMISTRY, MULTIDISCIPLINARY | 4+3 CYCLOADDITION REACTION | ALKALOIDS
Journal Article
by Tang, XK and Xue, J and Yang, YY and Ko, TP and Chen, CY and Dai, LH and Guo, RT and Zhang, YH and Chen, CC
RSC ADVANCES, ISSN 2046-2069, 2019, Volume 9, Issue 23, pp. 13182 - 13185
The Stig cyclases from Stigonematalean cyanobacteria are classified as a novel type of calcium-dependent cyclases which catalyze an uncommon reaction cascade... 
CARBOHYDRATE-BINDING MODULES | CHEMISTRY, MULTIDISCIPLINARY | HAPALINDOLE
Journal Article
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 07/2017, Volume 56, Issue 31, pp. 9087 - 9090
Inorganic macrocycles, based on non‐carbon backbones, present exciting synthetic challenges in the systematic assembly of inorganic molecules, as well as new... 
modular synthesis | X-ray structural analysis | macrocycles | phosphazanes | AMBIGUINE | IRON | IDENTIFICATION | FISCHERINDOLE | CHEMISTRY, MULTIDISCIPLINARY | HAPALOSIPHON-WELWITSCHII | HAPALINDOLE-TYPE ALKALOIDS | BIOGENESIS | BIOSYNTHESIS | ISONITRILE | HALOGENASE | Modularity
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 04/2011, Volume 133, Issue 15, pp. 5798 - 5801
Journal Article