HAEMATOLOGICA, ISSN 0390-6078, 08/2019, Volume 104, Issue 9, pp. 1696 - 1699
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 07/2018, Volume 24, Issue 42, p. n/a
Gadolinium ions can be caged within the water‐filled central cavity of insulin hexamers. These stable assemblies possess very high relaxivities as MRI contrast...
environmentally sensitive | insulin hexamer | proteins | contrast agent | gadolinium | Magnetic resonance imaging | Gadolinium | Insulin | Contrast agents | Hexamers | Contrast media
environmentally sensitive | insulin hexamer | proteins | contrast agent | gadolinium | Magnetic resonance imaging | Gadolinium | Insulin | Contrast agents | Hexamers | Contrast media
Journal Article
BBA - Proteins and Proteomics, ISSN 1570-9639, 09/2015, Volume 1854, Issue 9, pp. 1229 - 1237
Glutamate decarboxylase (GAD) is a pyridoxal 5′-phosphate (PLP)-dependent enzyme that catalyzes the α-decarboxylation of glutamate to γ-aminobutyrate. A unique...
Dimer–hexamer equilibrium | Glutamate decarboxylase | N-terminal domain | Calmodulin | Dimer?hexamer equilibrium | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | CLASSIFICATION | Dimer-hexamer equilibrium | BIOPHYSICS | METABOLISM | CALMODULIN-BINDING PROTEINS | GABA | GAMMA-AMINOBUTYRIC-ACID | STRESS | Index Medicus
Dimer–hexamer equilibrium | Glutamate decarboxylase | N-terminal domain | Calmodulin | Dimer?hexamer equilibrium | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | CLASSIFICATION | Dimer-hexamer equilibrium | BIOPHYSICS | METABOLISM | CALMODULIN-BINDING PROTEINS | GABA | GAMMA-AMINOBUTYRIC-ACID | STRESS | Index Medicus
Journal Article
SCIENCE, ISSN 0036-8075, 03/2016, Volume 351, Issue 6279, pp. 1268 - 1268
Water plays a central role in scientific disciplines ranging from geology to astronomy to biology. Yet it is an extraordinarily dif cult liquid to understand...
HEXAMER | CAGE | MULTIDISCIPLINARY SCIENCES | LIQUID
HEXAMER | CAGE | MULTIDISCIPLINARY SCIENCES | LIQUID
Journal Article
International Journal of Biological Sciences, ISSN 1449-2288, 05/2018, Volume 14, Issue 8, pp. 883 - 891
Meiotic recombination caused by meiotic double-strand DNA breaks. In some regions the frequency of DNA recombination is relatively higher, while in other...
5-step rules | Recombination spot | Key hexamers | PseKNC | Webserver | SVM | SEQUENCE-BASED PREDICTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOUBLE-STRAND BREAKS | DINUCLEOTIDE COMPOSITION | ANTIMICROBIAL PEPTIDES | PSEUDO | FEATURE-SELECTION | PROTEIN SUBCELLULAR-LOCALIZATION | DISCRIMINANT ALGORITHM | AMINO-ACID-COMPOSITION | WEB SERVER
5-step rules | Recombination spot | Key hexamers | PseKNC | Webserver | SVM | SEQUENCE-BASED PREDICTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOUBLE-STRAND BREAKS | DINUCLEOTIDE COMPOSITION | ANTIMICROBIAL PEPTIDES | PSEUDO | FEATURE-SELECTION | PROTEIN SUBCELLULAR-LOCALIZATION | DISCRIMINANT ALGORITHM | AMINO-ACID-COMPOSITION | WEB SERVER
Journal Article
6.
Full Text
DNA translocation mechanism of the MCM complex and implications for replication initiation
NATURE COMMUNICATIONS, ISSN 2041-1723, 07/2019, Volume 10, Issue 1, pp. 3117 - 13
The DNA translocation activity of the minichromosome maintenance (MCM) complex powers DNA strand separation of the replication forks of eukaryotes and archaea....
ORGANIZATION | PROTEIN | CDC45 | ARCHAEAL MCM | STRUCTURAL BASIS | CRYSTAL-STRUCTURE | GINS | MULTIDISCIPLINARY SCIENCES | EUKARYOTIC CMG HELICASE | CRYSTALLOGRAPHY | DOUBLE-HEXAMER | Translocation | Single-stranded DNA | Nucleotide sequence | Archaea | Hexamers | Replication initiation | Nucleotides | Cofactors | Replication forks | DNA biosynthesis | Interfaces | Conserved sequence | Eukaryotes | Replication | Deoxyribonucleic acid--DNA | Crystal structure
ORGANIZATION | PROTEIN | CDC45 | ARCHAEAL MCM | STRUCTURAL BASIS | CRYSTAL-STRUCTURE | GINS | MULTIDISCIPLINARY SCIENCES | EUKARYOTIC CMG HELICASE | CRYSTALLOGRAPHY | DOUBLE-HEXAMER | Translocation | Single-stranded DNA | Nucleotide sequence | Archaea | Hexamers | Replication initiation | Nucleotides | Cofactors | Replication forks | DNA biosynthesis | Interfaces | Conserved sequence | Eukaryotes | Replication | Deoxyribonucleic acid--DNA | Crystal structure
Journal Article
Angewandte Chemie, ISSN 1433-7851, 03/2019, Volume 58, Issue 12, pp. 3885 - 3889
Herein, two new classes of macrocyclic compounds, terphen[n]arenes (TPns) (n=3–6) and quaterphen[n]arenes (QPns) (n=3–6), were designed and synthesized by a...
Macrocyclic compounds | Aqueous solutions | Gels | Aromatic compounds | Hexamers | Chemical synthesis | Face | Supramolecular compounds | Assembly | Monomers | Iodine | Fibers
Macrocyclic compounds | Aqueous solutions | Gels | Aromatic compounds | Hexamers | Chemical synthesis | Face | Supramolecular compounds | Assembly | Monomers | Iodine | Fibers
Journal Article
Journal of Chemical Physics, ISSN 0021-9606, 2008, Volume 129, Issue 19, p. 194111
Second order Moller-Plesset perturbation theory at the complete basis set limit and diffusion quantum Monte Carlo are used to examine several low energy...
dissociation energies | liquid structure | diffusion | MOLECULAR-DYNAMICS | NETWORK | molecular configurations | APPROXIMATION | AB-INITIO | INTERACTION ENERGIES | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | CHEMISTRY, PHYSICAL | BINDING-ENERGIES | hydrogen bonds | water | Monte Carlo methods | WAVE-FUNCTIONS | perturbation theory | density functional theory | liquid theory | FORCES | SIMULATIONS | van der Waals forces | ADJUSTABLE-PARAMETERS
dissociation energies | liquid structure | diffusion | MOLECULAR-DYNAMICS | NETWORK | molecular configurations | APPROXIMATION | AB-INITIO | INTERACTION ENERGIES | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | CHEMISTRY, PHYSICAL | BINDING-ENERGIES | hydrogen bonds | water | Monte Carlo methods | WAVE-FUNCTIONS | perturbation theory | density functional theory | liquid theory | FORCES | SIMULATIONS | van der Waals forces | ADJUSTABLE-PARAMETERS
Journal Article
SOLID STATE IONICS, ISSN 0167-2738, 08/2018, Volume 321, pp. 43 - 47
A coordination polymer with ordered and non-acidic water-duster guest molecules, [Zn(cis-chdc)(bpp)]center dot 6H(2)O (denoted as Zn-2-(H2O)(12), H(2)chdc =...
PATHWAYS | Coordination polymers | PHYSICS, CONDENSED MATTER | METAL-ORGANIC FRAMEWORKS | Guest arrangement | CRYSTAL-STRUCTURE | CHEMISTRY, PHYSICAL | HEXAMERS | Proton conducting solid electrolytes
PATHWAYS | Coordination polymers | PHYSICS, CONDENSED MATTER | METAL-ORGANIC FRAMEWORKS | Guest arrangement | CRYSTAL-STRUCTURE | CHEMISTRY, PHYSICAL | HEXAMERS | Proton conducting solid electrolytes
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2018, Volume 115, Issue 27
Cyanobacteria are important photosynthetic organisms inhabiting a range of dynamic environments. This phylum is distinctive among photosynthetic organisms in...
Microcystis aeruginosa | BASIC BIOLOGICAL SCIENCES | crystal structure | hexamer | redox
Microcystis aeruginosa | BASIC BIOLOGICAL SCIENCES | crystal structure | hexamer | redox
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2018, Volume 115, Issue 30, p. E7101
The three mammalian nonmuscle myosin 2 (NM2) monomers, like all class 2 myosin monomers, are hexamers of two identical heavy (long) chains and two pairs of...
Coils | Head | Hexamers | Polymerization | Forming | Mammals | Monomers | Proteins | Depolymerization | Molecules | Filaments | Actin | Light chains | Myosin | Dimers | Polymers | Dismantling | Adenosine triphosphatase
Coils | Head | Hexamers | Polymerization | Forming | Mammals | Monomers | Proteins | Depolymerization | Molecules | Filaments | Actin | Light chains | Myosin | Dimers | Polymers | Dismantling | Adenosine triphosphatase
Journal Article
JBIC Journal of Biological Inorganic Chemistry, ISSN 0949-8257, 3/2018, Volume 23, Issue 2, pp. 253 - 259
DNA oligomer duplexes with alternating cytosines and guanines in their sequence tend to form helices of the Z-DNA type, where the sugar and phosphate backbone...
Life Sciences | Biochemistry, general | Ca 2+ :DNA complex | Microbiology | Z-DNA crystal structure | Z-DNA hexamer duplex unusual Ca 2+ coordination | DNA complex | Z-DNA hexamer duplex unusual Ca | coordination | DOUBLE-HELICAL DNA | Ca2+:DNA complex | BIOCHEMISTRY & MOLECULAR BIOLOGY | Z-DNA hexamer duplex unusual Ca2+ coordination | RESOLUTION | CONFORMATION | CHEMISTRY, INORGANIC & NUCLEAR
Life Sciences | Biochemistry, general | Ca 2+ :DNA complex | Microbiology | Z-DNA crystal structure | Z-DNA hexamer duplex unusual Ca 2+ coordination | DNA complex | Z-DNA hexamer duplex unusual Ca | coordination | DOUBLE-HELICAL DNA | Ca2+:DNA complex | BIOCHEMISTRY & MOLECULAR BIOLOGY | Z-DNA hexamer duplex unusual Ca2+ coordination | RESOLUTION | CONFORMATION | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e64860
Insulin signaling is essential for beta-cell survival and proliferation in vivo. Insulin also has potent mitogenic and anti-apoptotic actions on cultured...
SUBCUTANEOUS INJECTION | APOPTOSIS | PHARMACOKINETIC MODEL | ANALOGS | GLUCOSE | MULTIDISCIPLINARY SCIENCES | RECEPTOR | ENDOGENOUS INSULIN | BETA-CELL MASS | SECRETION | INJECTED SOLUBLE INSULIN | Insulin-Secreting Cells - physiology | Autocrine Communication | Extracellular Fluid - metabolism | Algorithms | Insulin - physiology | Signal Transduction | Glucose - physiology | Models, Biological | Humans | Islets of Langerhans - cytology | Kinetics | Type 2 diabetes | Taste | Insulin | Apoptosis | Physiological effects | Parameter estimation | Paracrine signalling | Glucose | Monomers | Rodents | Physiology | Mathematical models | Autocrine signalling | Pancreas | Drug dosages | Cell survival | Experimental data | Hexamers | Crystals | Data processing | Studies | Pancreatic cancer | Insulin resistance | In vivo methods and tests | Dimers | Diabetes | Islets of Langerhans
SUBCUTANEOUS INJECTION | APOPTOSIS | PHARMACOKINETIC MODEL | ANALOGS | GLUCOSE | MULTIDISCIPLINARY SCIENCES | RECEPTOR | ENDOGENOUS INSULIN | BETA-CELL MASS | SECRETION | INJECTED SOLUBLE INSULIN | Insulin-Secreting Cells - physiology | Autocrine Communication | Extracellular Fluid - metabolism | Algorithms | Insulin - physiology | Signal Transduction | Glucose - physiology | Models, Biological | Humans | Islets of Langerhans - cytology | Kinetics | Type 2 diabetes | Taste | Insulin | Apoptosis | Physiological effects | Parameter estimation | Paracrine signalling | Glucose | Monomers | Rodents | Physiology | Mathematical models | Autocrine signalling | Pancreas | Drug dosages | Cell survival | Experimental data | Hexamers | Crystals | Data processing | Studies | Pancreatic cancer | Insulin resistance | In vivo methods and tests | Dimers | Diabetes | Islets of Langerhans
Journal Article
European Journal of Inorganic Chemistry, ISSN 1434-1948, 08/2013, Volume 2013, Issue 24, pp. 4159 - 4163
The electrochemical hydrolysis of thorium(IV) was monitored by a combination of high‐energy X‐ray scattering (HEXS) and NMR spectroscopy. Once formed,...
Nanoparticles | X‐ray scattering | Actinides | Hexamers | Cluster compounds | X-ray scattering | Hydrolysis | Glycine | Nuclear magnetic resonance spectroscopy
Nanoparticles | X‐ray scattering | Actinides | Hexamers | Cluster compounds | X-ray scattering | Hydrolysis | Glycine | Nuclear magnetic resonance spectroscopy
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 45, p. E9529
During replication initiation, the core component of the helicase -- the Mcm2-7 hexamer -- is loaded on origin DNA as a double hexamer (DH). The two...
DNA biosynthesis | DNA helicase | Presenilin 1 | Hexamers | Replication initiation | Extrusion | Zinc finger proteins | Deoxyribonucleic acid--DNA | Binding sites | Zinc
DNA biosynthesis | DNA helicase | Presenilin 1 | Hexamers | Replication initiation | Extrusion | Zinc finger proteins | Deoxyribonucleic acid--DNA | Binding sites | Zinc
Journal Article
ORGANIC CHEMISTRY FRONTIERS, ISSN 2052-4129, 05/2019, Volume 6, Issue 9, pp. 1397 - 1402
Open-cage fullerene derivatives with up to three hydroxyl groups on the rim of an orifice were prepared through modification of functional groups followed by...
HETEROFULLERENES | HEXAMER | MOLECULE | CHEMISTRY, ORGANIC | WATER
HETEROFULLERENES | HEXAMER | MOLECULE | CHEMISTRY, ORGANIC | WATER
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 03/2019, Volume 116, Issue 10, pp. 4256 - 4264
Assembly of paramyxoviral nucleocapsids on the RNA genome is an essential step in the viral cycle. The structural basis of this process has remained obscure...
HEXAMER | COMPLEX | DOMAIN | nucleocapsids | CRYSTAL-STRUCTURE | RECONSTRUCTION | MULTIDISCIPLINARY SCIENCES | BEAM-INDUCED MOTION | REFINEMENT | NMR | cryoelectron microscopy | NUCLEOPROTEIN | assembly | VESICULAR STOMATITIS-VIRUS | PROTEINS | measles virus | Genetic aspects | RNA | Viral proteins | Structure | Measles virus | RNA viruses | Nuclear magnetic resonance--NMR | Hexamers | Nucleocapsids | Adenine | Viruses | Genomes | Nucleotides | RNA polymerase | Nucleic acids | Ribonucleic acid--RNA | DNA-directed RNA polymerase | RNA-directed RNA polymerase | Gene sequencing | Polymerase | Encapsidation | Microscopy | Measles | Kinetics | Mutation | Gene mapping | RNA processing | Assembly | Binding sites | Life Sciences | Biomolecules | Biochemistry, Molecular Biology | Biological Sciences | PNAS Plus
HEXAMER | COMPLEX | DOMAIN | nucleocapsids | CRYSTAL-STRUCTURE | RECONSTRUCTION | MULTIDISCIPLINARY SCIENCES | BEAM-INDUCED MOTION | REFINEMENT | NMR | cryoelectron microscopy | NUCLEOPROTEIN | assembly | VESICULAR STOMATITIS-VIRUS | PROTEINS | measles virus | Genetic aspects | RNA | Viral proteins | Structure | Measles virus | RNA viruses | Nuclear magnetic resonance--NMR | Hexamers | Nucleocapsids | Adenine | Viruses | Genomes | Nucleotides | RNA polymerase | Nucleic acids | Ribonucleic acid--RNA | DNA-directed RNA polymerase | RNA-directed RNA polymerase | Gene sequencing | Polymerase | Encapsidation | Microscopy | Measles | Kinetics | Mutation | Gene mapping | RNA processing | Assembly | Binding sites | Life Sciences | Biomolecules | Biochemistry, Molecular Biology | Biological Sciences | PNAS Plus
Journal Article
The Journal of Physical Chemistry Letters, ISSN 1948-7185, 04/2013, Volume 4, Issue 7, pp. 1104 - 1108
Signature IR spectra of isomers of the water hexamer in the spectral range 3000–3800 cm–1 have been reported by experimentalists, but crucial theoretical...
Spectroscopy, Photochemistry, and Excited States | octomer | bend-overtone | heptamer | ring hexamer | local-monomer | water book hexamer | RELATIVE ENERGIES | CAGE | CLUSTERS | MATERIALS SCIENCE, MULTIDISCIPLINARY | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | ISOMERS | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | PRISM
Spectroscopy, Photochemistry, and Excited States | octomer | bend-overtone | heptamer | ring hexamer | local-monomer | water book hexamer | RELATIVE ENERGIES | CAGE | CLUSTERS | MATERIALS SCIENCE, MULTIDISCIPLINARY | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | ISOMERS | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | PRISM
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 07/2017, Volume 56, Issue 29, pp. 8376 - 8383
Uniform synthetic polymers with precisely defined molar mass and monomer sequence (primary structure) have many potential high‐value applications. However, a...
sequence control | photopolymerization | RAFT polymerization | single unit monomer insertion | ACRYLATE OLIGOMERS | POLYMERS | ITERATIVE EXPONENTIAL-GROWTH | MULTIBLOCK COPOLYMERS | STEP | CHEMISTRY, MULTIDISCIPLINARY | CHAIN | REGULATED VINYL COPOLYMERS | MEDIATED POLYMERIZATION | N-PHENYLMALEIMIDE | RADICAL POLYMERIZATIONS | Oligomers | Polymerization | Construction | Graft copolymers | Energy use | Hexamers | Amino acid sequence | Insertion | Polyethylene terephthalate | Materials selection | Trimers | Selectivity | Chains (polymeric) | Fragmentation | Copolymers | Reagents | Dimers | Polymers | Chemical synthesis | Energy transfer | Activation energy
sequence control | photopolymerization | RAFT polymerization | single unit monomer insertion | ACRYLATE OLIGOMERS | POLYMERS | ITERATIVE EXPONENTIAL-GROWTH | MULTIBLOCK COPOLYMERS | STEP | CHEMISTRY, MULTIDISCIPLINARY | CHAIN | REGULATED VINYL COPOLYMERS | MEDIATED POLYMERIZATION | N-PHENYLMALEIMIDE | RADICAL POLYMERIZATIONS | Oligomers | Polymerization | Construction | Graft copolymers | Energy use | Hexamers | Amino acid sequence | Insertion | Polyethylene terephthalate | Materials selection | Trimers | Selectivity | Chains (polymeric) | Fragmentation | Copolymers | Reagents | Dimers | Polymers | Chemical synthesis | Energy transfer | Activation energy
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2016, Volume 14, Issue 42, pp. 9961 - 9965
By using polar DMF to relax the H-bonded rigid backbone and to lower the energetic penalty associated with the sterically-crowded environment, the yields for...
STACKING | RECOGNITION | LIGANDS | CHEMISTRY, ORGANIC | OLIGOAMIDE MACROCYCLES | HEXAMERS | METAL-IONS | RECEPTORS | FLUOROPENTAMERS | HIGHLY EFFICIENT
STACKING | RECOGNITION | LIGANDS | CHEMISTRY, ORGANIC | OLIGOAMIDE MACROCYCLES | HEXAMERS | METAL-IONS | RECEPTORS | FLUOROPENTAMERS | HIGHLY EFFICIENT
Journal Article
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