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Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 5, pp. 462 - 466
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 19, Issue 3, pp. 305 - 316
Mutations in the , , and pathways are obligate events in the pathogenesis of human glioblastomas. We induced various combinations of deletions in these tumor... 
MOUSE-BRAIN | SOMA SIZE | ONCOLOGY | NEURAL STEM/PROGENITOR CELLS | GLIOBLASTOMA-MULTIFORME | LHERMITTE-DUCLOS-DISEASE | INTEGRATED GENOMIC ANALYSIS | IN-VIVO | STEM-CELL | CENTRAL-NERVOUS-SYSTEM | EXPRESSION | CELL BIOLOGY | Immunohistochemistry | Humans | Male | Gene Expression Profiling | Mice, 129 Strain | Brain Neoplasms - metabolism | Tumor Suppressor Protein p53 - genetics | Brain - metabolism | Astrocytoma - pathology | Glioblastoma - genetics | Time Factors | Female | Glioblastoma - metabolism | Astrocytoma - genetics | Astrocytoma - metabolism | PTEN Phosphohydrolase - genetics | Mice, Inbred C57BL | Retinoblastoma Protein - metabolism | Kaplan-Meier Estimate | Tumor Suppressor Protein p53 - metabolism | Brain Neoplasms - genetics | PTEN Phosphohydrolase - metabolism | In Situ Hybridization, Fluorescence | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Animals | Gene Amplification | Receptor Protein-Tyrosine Kinases - genetics | Retinoblastoma Protein - genetics | Glioblastoma - pathology | Brain - pathology | Mice | Gene expression | Tumor proteins | Gliomas | Genes | Brain | Animal models | Astrocytes | Brain tumors | Glioblastoma | Retinoblastoma protein | MAP kinase | Gene deletion | Nodes | p53 protein | 1-Phosphatidylinositol 3-kinase | Glioma | Lymphocytes B | Neural stem cells | Tumor suppressor genes | Cooperativity | Mutation | Astrocytoma | Niches | PTEN protein | Tumors
Journal Article
Journal of Cancer Research and Clinical Oncology, ISSN 0171-5216, 04/2019, Volume 145, Issue 4, pp. 1037 - 1042
PurposeAntiangiogenic treatment approaches have failed to improve outcome in randomized trials of high-grade astrocytoma. One key mechanism of resistance to... 
Regorafenib | High-grade glioma | Astrocytoma | Glioblastoma | TRIAL | ANGIOGENESIS | ONCOLOGY | BEVACIZUMAB | PATTERNS | Complications and side effects | Care and treatment | Relapse | Gliomas | Diseases
Journal Article
2015, ISBN 9781369133646
Paediatric high-grade astrocytomas (pHGA) and diffuse-intrinsic-pontine-gliomas (DIPG) are devastating paediatric malignancies for which there are no effective... 
Medicine
eBook
Journal of Neuropathology & Experimental Neurology, ISSN 0022-3069, 01/2019, Volume 78, Issue 1, pp. 57 - 64
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2013, Volume 110, Issue 44, pp. 17933 - 17938
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. 2049 - 2049
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2015, Volume 17, Issue suppl 5, pp. v81.2 - v81
Journal Article
Journal of neurosurgery, ISSN 0022-3085, 03/2019, pp. 1 - 8
OBJECTIVEThe aim of this study was to investigate the relationship between extent of resection (EOR) and survival in terms of clinical, molecular, and... 
Journal Article