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1. Histone deacetylases
: the biology and clinical implication
by Yao, Tso-Pang and Seto, Edward
2011, First, Handbook of experimental pharmacology, ISBN 9783642216312, Volume 206, xi, 260
The book highlights work from many different labs that taught us abnormal HDACs potentially contribute to the development or progression of many human diseases... 
Sirtuins | Histone deacetylase | drug therapy | physiology | Histone Deacetylases | Histone Deacetylase Inhibitors | Neoplasms | Medicine: General Issues | Histones | Protein Science | Gene Function | Biomedicine | Laboratory Medicine | Pharmacology/Toxicology | Posttranslational Modification | Biomedicine general
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2. Full Text Rice histone deacetylase 10 and Arabidopsis histone deacetylase 14 genes encode N‐acetylserotonin deacetylase, which catalyzes conversion of N‐acetylserotonin into serotonin, a reverse reaction for melatonin biosynthesis in plants
by Lee, Kyungjin and Lee, Hyoung Yool and Back, Kyoungwhan
Journal of Pineal Research, ISSN 0742-3098, 03/2018, Volume 64, Issue 2, pp. e12460 - n/a
In plants, melatonin production is strictly regulated, unlike the production of its precursor, serotonin, which is highly inducible in response to stimuli,... 
N‐acetyltryptamine deacetylase | rice | Arabidopsis | melatonin deacetylase | N-acetyltryptamine deacetylase | LOCALIZATION | PHYSIOLOGY | ACID | METHYLTRANSFERASE | CADMIUM STRESS | TOLERANCE | SUPPRESSION | NEUROSCIENCES | SULFOTRANSFERASE | ENDOCRINOLOGY & METABOLISM | MOLECULAR-CLONING | EXPRESSION | ACETYLTRANSFERASE | Arylalkylamine N-Acetyltransferase - metabolism | Oryza - metabolism | Serotonin - metabolism | Serotonin - analogs & derivatives | Histone Deacetylases - metabolism | Melatonin - biosynthesis | Plant Proteins - metabolism | Phylogeny | Arabidopsis - metabolism | Physiological aspects | Phenols | Melatonin | Serotonin | Genes
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3. Full Text The Current State of NAD+‐Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets
by Schiedel, Matthias and Robaa, Dina and Rumpf, Tobias and Sippl, Wolfgang and Jung, Manfred
Medicinal Research Reviews, ISSN 0198-6325, 01/2018, Volume 38, Issue 1, pp. 147 - 200
Sirtuins are NAD+‐dependent protein deacylases that cleave off acetyl, as well as other acyl groups, from the ε‐amino group of lysines in histones and other... 
KDAC | lysine deacetylases | resveratrol | sirtuins | epigenetics | RNA-POLYMERASE-I | PROTEIN-KINASE-C | CHEMISTRY, MEDICINAL | EPSILON-THIOACETYL-LYSINE | FREE-ENERGY CALCULATIONS | PROMOTES CELL-SURVIVAL | FATTY-ACID OXIDATION | SUPPRESSES INFLAMMATORY RESPONSES | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | NAD-DEPENDENT DEACETYLASE | SMALL-MOLECULE ACTIVATORS | Epigenetic inheritance | Nervous system diseases | Enzyme inhibitors | Lysine | Pharmacy | Resveratrol | Physiological aspects | Histones | DNA binding proteins | Health aspects | Cells
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4. Full Text Histone deacetylases and cancer
by Glozak, M.A and Seto, E
Oncogene, ISSN 0950-9232, 08/2007, Volume 26, Issue 37, pp. 5420 - 5432
Histone deacetylases ( HDACs) regulate the expression and activity of numerous proteins involved in both cancer initiation and cancer progression. By removal... 
HDAC inhibitors | Acetylation | Deacetylation | Cancer | HDAC | DNA-BINDING | DEPENDENT TRANSCRIPTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACUTE MYELOID-LEUKEMIA | CELL-SURVIVAL | CELL BIOLOGY | acetylation | TRANSCRIPTION FACTOR GATA-1 | ONCOLOGY | deacetylation | IN-VIVO | PROSTATE-CANCER | GENETICS & HEREDITY | ZINC-FINGER PROTEIN | REPRESS TRANSCRIPTION | cancer | NF-KAPPA-B | Transcription Factors - metabolism | Cell Proliferation | Histone Deacetylases - genetics | Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Neoplasms - enzymology | Histone Deacetylases - metabolism | Cell Differentiation | Protein Processing, Post-Translational | Histones - metabolism | Neoplasms - pathology | Physiological aspects | Histones | Genetic aspects | DNA binding proteins | Research | Enzymes | Oncology | Inhibitor drugs | Cellular biology | Molecular biology | Gene expression
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5. Full Text Histone deacetylases and cancer
by Barneda-Zahonero, Bruna and Parra, Maribel
Molecular Oncology, ISSN 1574-7891, 12/2012, Volume 6, Issue 6, pp. 579 - 589
Reversible acetylation of histone and non-histone proteins is one of the most abundant post-translational modifications in eukaryotic cells. Protein... 
Protein acetylation | Histone deacetylases | Cancer | HDAC INHIBITOR | DIFFERENTIAL EXPRESSION | POSITIVE BREAST-CANCER | LUNG-CANCER | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | TUMOR-CELL PROLIFERATION | ACUTE LYMPHOBLASTIC-LEUKEMIA | PROSTATE-CANCER | GENE-EXPRESSION | CLASS-II | Gene Expression Regulation, Enzymologic | Neoplasms - metabolism | Histone Deacetylases - classification | Animals | Histone Deacetylases - genetics | Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Neoplasms - enzymology | Histone Deacetylases - metabolism | Acetylation | Histones - metabolism | Enzymes | Analysis | Oncology, Experimental | Histones | DNA binding proteins | Research | Histone deacetylase | Phosphorylation | Transcription factors | Smooth muscle | Gene expression | Drug development | Proteins | Deacetylation | Cell cycle | DNA methylation | Deoxyribonucleic acid--DNA | Apoptosis | Review | Special Papers
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6. Full Text Histone deacetylases
by Marks, Paul A and Miller, Thomas and Richon, Victoria M
Current Opinion in Pharmacology, ISSN 1471-4892, 2003, Volume 3, Issue 4, pp. 344 - 351
Post-translational modification of the histones of chromatin has a fundamental role in regulating gene expression. Enzymes involved in these epigenetic events... 
POTENT | ACETYLATION | SMALL-MOLECULE INHIBITORS | IN-VIVO | PHARMACOLOGY & PHARMACY | CELL-CYCLE | ANTITUMOR-ACTIVITY | DEPSIPEPTIDE FR901228 | TRICHOSTATIN-A | CANCER | EXPRESSION | Humans | Enzyme Inhibitors - pharmacology | Gene Expression Regulation, Neoplastic | Neoplasms - enzymology | Antineoplastic Agents - therapeutic use | Clinical Trials as Topic | Structure-Activity Relationship | Enzyme Inhibitors - therapeutic use | Neoplasms - drug therapy | Animals | Drug Design | Antineoplastic Agents - pharmacology | Histone Deacetylase Inhibitors
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