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1. Full Text Behavioral Recovery in MPTP-Treated Monkeys: Neurochemical Mechanisms Studied by Intrastriatal Microdialysis
by Boulet, Sabrina and Mounayar, Stephanie and Poupard, Annie and Bertrand, Anne and Jan, Caroline and Pessiglione, Mathias and Hirsch, Etienne C and Feuerstein, Claude and Francois, Chantal and Feger, Jean and Savasta, Marc and Tremblay, Leon
Journal of Neuroscience, ISSN 0270-6474, 09/2008, Volume 28, Issue 38, pp. 9575 - 9584
Parkinson's disease (PD) patients express motor symptoms only after 60-80% striatal dopamine (DA) depletion. The presymptomatic phase of the disease may be... 
Primate | Microdialysis | Parkinson's disease | MPTP | Serotonin | Recovery | MOTOR ASYMPTOMATIC MONKEYS | FREELY MOVING RATS | NONHUMAN-PRIMATES | recovery | DOPAMINE TURNOVER | SUBSTANTIA-NIGRA | NEUROSCIENCES | primate | serotonin | CHRONIC EXPOSURE | microdialysis | EXTRACELLULAR LEVELS | STRIATAL GLUTAMATE | POSTMORTEM BRAINS | PARKINSONS-DISEASE | Extracellular Fluid - chemistry | Parkinsonian Disorders - physiopathology | 3,4-Dihydroxyphenylacetic Acid - metabolism | gamma-Aminobutyric Acid - metabolism | Neurotransmitter Agents - metabolism | Cercopithecus aethiops | Behavior, Animal - physiology | Male | Hydroxyindoleacetic Acid - metabolism | Corpus Striatum - metabolism | Corpus Striatum - chemistry | Down-Regulation - physiology | Parkinsonian Disorders - metabolism | Extracellular Fluid - metabolism | Animals | Homovanillic Acid - metabolism | Movement - physiology | Serotonin - metabolism | Up-Regulation - physiology | Recovery of Function - physiology | Glutamic Acid - metabolism | Dopamine - metabolism | Disease Models, Animal | Parkinsonian Disorders | gamma-Aminobutyric Acid | Up-Regulation | Movement | Dopamine | Homovanillic Acid | Down-Regulation | Recovery of Function | Behavior, Animal | Glutamic Acid | Neurotransmitter Agents | Extracellular Fluid | 3,4-Dihydroxyphenylacetic Acid | Corpus Striatum | Hydroxyindoleacetic Acid
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2. Full Text Determination of three Tumor Biomarkers (Homovanillic Acid, Vanillylmandelic Acid, and 5‐Hydroxyindole‐3‐Acetic Acid) Using Flow Injection Analysis with Amperometric Detection
by Němečková‐Makrlíková, Anna and Matysik, Frank‐Michael and Navrátil, Tomáš and Barek, Jiří and Vyskočil, Vlastimil
Electroanalysis, ISSN 1040-0397, 02/2019, Volume 31, Issue 2, pp. 303 - 308
Flow injection analysis with amperometric detection (FIA‐AD) at screen‐printed carbon electrodes (SPCEs) in optimum medium of Britton‐Robinson buffer (0.04 mol... 
5-Hydroxyindole-3-acetic acid | Amperometric detection | Flow injection analysis | Vanillylmandelic acid | Homovanillic acid | Screen-printed carbon electrodes | ELECTROCHEMISTRY | CHEMISTRY, ANALYTICAL | VOLTAMMETRIC DETERMINATION | ASSAY | 5-HYDROXY-3-INDOLEACETIC ACID | NEUROBLASTOMA | ACETIC-ACID | PERFORMANCE LIQUID-CHROMATOGRAPHY | CATECHOLAMINE METABOLITES | ELECTROCHEMICAL METHODS | URINE | DOPAMINE | Usage | Acetic acid | Biological markers | Analysis | Organic acids | Tumors
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3. Full Text Voltammetric Determination of Tumor Biomarkers for Neuroblastoma (Homovanillic Acid, Vanillylmandelic Acid, and 5‐Hydroxyindole‐3‐acetic Acid) at Screen‐printed Carbon Electrodes
by Makrlíková, Anna and Ktena, Evangelia and Economou, Anastasios and Fischer, Jan and Navrátil, Tomáš and Barek, Jiří and Vyskočil, Vlastimil
Electroanalysis, ISSN 1040-0397, 01/2017, Volume 29, Issue 1, pp. 146 - 153
Three tumor biomarkers (homovanillic acid (HVA), vanillylmandelic acid (VMA), and 5‐hydroxyindole‐3‐acetic acid (5‐HIAA)) have been determined by differential... 
5-Hydroxyindole-3-acetic acid | Vanillylmandelic acid | Homovanillic acid | Differential pulse voltammetry | Screen-printed carbon electrodes | ELECTROCHEMISTRY | CHEMISTRY, ANALYTICAL | METABOLITES | ASSAY | MARKERS | MASS-SPECTROMETRY | PERFORMANCE LIQUID-CHROMATOGRAPHY | EXTRACTION | ELECTROCHEMICAL DETECTION | HUMAN-URINE | CAPILLARY-ELECTROPHORESIS | HPLC | Electrodes | Acetic acid | Biological markers | Organic acids | Tumors | Electrolytic analysis | Biomarkers | Voltammetry | Buffers | Carbon | Optimization
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4. Full Text Validation of a multi-analyte HPLC-DAD method for determination of uric acid, creatinine, homovanillic acid, niacinamide, hippuric acid, indole-3-acetic acid and 2-methylhippuric acid in human urine
by Remane, Daniela and Grunwald, Soeren and Hoeke, Henrike and Mueller, Andrea and Roeder, Stefan and von Bergen, Martin and Wissenbach, Dirk K
Journal of Chromatography B, ISSN 1570-0232, 08/2015, Volume 998-999, pp. 40 - 44
During the last decades exposure sciences and epidemiological studies attracts more attention to unravel the mechanisms for the development of chronic... 
Validation | Creatinine | Urine | Uric acid | HPLC-DAD | Hippuric acid | PROGENITORS | CHEMISTRY, ANALYTICAL | BIOCHEMICAL RESEARCH METHODS | MASS-SPECTROMETRY | LIQUID-CHROMATOGRAPHY | GUT MICROBIOME | STRESS | EXPRESSION | EXPOSURE | AGE | EXPOSOME | Uric Acid - urine | Chromatography, High Pressure Liquid - methods | Humans | Chromatography, High Pressure Liquid - instrumentation | Niacinamide - urine | Indoleacetic Acids - urine | Creatinine - urine | Homovanillic Acid - urine | Hippurates - urine | Niacinamide | Auxin | Analysis | Pharmacy | Acetic acid | Methods | High performance liquid chromatography | Organic acids
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5. Full Text Poly‐(Alizarin Red S)‐Modified Glassy Carbon Electrode for Simultaneous Electrochemical Determination of Levodopa, Homovanillic Acid and Ascorbic Acid
by Hatefi‐Mehrjardi, Abdolhamid and Ghaemi, Nasrin and Karimi, Mohammad Ali and Ghasemi, Masoumeh and Islami‐Ramchahi, Somaieh
Electroanalysis, ISSN 1040-0397, 11/2014, Volume 26, Issue 11, pp. 2491 - 2500
A polymeric film of Alizarin Red S was formed on a glassy carbon electrode and used for electrochemical detection of Levodopa (L‐DOPA) and homovanillic acid... 
Electrocatalysis | Simultaneous determination | Alizarin Red S | Ascorbic acid | Homovanillic acid | Modified glassy carbon electrode | Levodopa | ELECTROCHEMISTRY | CHEMISTRY, ANALYTICAL | VOLTAMMETRIC DETERMINATION | SENSOR | CEREBROSPINAL-FLUID | HUMAN SERUM | PASTE ELECTRODE | FOLIC-ACID | PHARMACEUTICAL FORMULATIONS | ELECTROCATALYTIC DETERMINATION | URIC-ACID | PARKINSONS-DISEASE | Vitamin C | Electric properties | Antiparkinsonian agents | Human | Electrodes | Anodizing | Resultants | Sensors | Glassy carbon | Alizarin
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6. Full Text HPLC–mass spectrometry method for quantitative detection of neuroendocrine tumor markers: Vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid
by Lionetto, Luana and Lostia, Alfonso M and Stigliano, Antonio and Cardelli, Patrizia and Simmaco, Maurizio
Clinica Chimica Acta, ISSN 0009-8981, 2008, Volume 398, Issue 1, pp. 53 - 56
The urinary excretion of vanillylmandelic acid (VMA), homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) can be increased in the presence of... 
5-hydroxyindoleacetic acid | Neuroblastic tumors | Vanillylmandelic acid | Homovanillic acid | LC–MS/MS | Carcinoid syndrome | LC-MS/MS | DIAGNOSIS | METABOLITES | CARCINOID-SYNDROME | CATECHOLAMINES | NEUROBLASTOMA | MEDICAL LABORATORY TECHNOLOGY | Serotonin - biosynthesis | Carcinoid Tumor - urine | Reproducibility of Results | Humans | Vanilmandelic Acid - urine | Neuroendocrine Tumors - urine | Neuroendocrine Tumors - diagnosis | Calibration | Chromatography, High Pressure Liquid | Neuroblastoma - diagnosis | Neuroblastoma - urine | Tandem Mass Spectrometry | Biomarkers, Tumor - urine | Mass Spectrometry | Indicators and Reagents | Hydroxyindoleacetic Acid - urine | Carcinoid Tumor - diagnosis | Homovanillic Acid - urine | Tryptophan | Methods | Tumors
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7. Plasma homovanillic acid in schizophrenia
: implications for presynaptic dopamine dysfunction
by Friedhoff, Arnold J and Amin, Farooq
1997, Progress in psychiatry., ISBN 0880484896, xv, 197
Dopamine | Pathophysiology | Homovanillic acid | Analysis | Schizophrenia | Physiological effect | Blood plasma
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8. Full Text Dystrobrevin-binding protein 1 gene ( DTNBP1 ) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers
by Andreou, Dimitrios and Saetre, Peter and Kähler, Anna K and Werge, Thomas and Andreassen, Ole A and Agartz, Ingrid and Sedvall, Göran C and Hall, Håkan and Terenius, Lars and Jönsson, Erik G and Medicinska fakulteten and Geriatrik and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för folkhälso- och vårdvetenskap
European Neuropsychopharmacology, ISSN 0924-977X, 2011, Volume 21, Issue 9, pp. 700 - 704
Abstract The dystrobrevin binding protein-1 ( DTNBP1 ) gene encodes dysbindin-1, a protein involved in neurodevelopmental and neurochemical processes related... 
Internal Medicine | Psychiatry | Dystrobrevin-binding protein 1 gene ( DTNBP1) | Homovanillic acid (HVA) | Cerebrospinal fluid (CSF) | 5-Hydroxyindoleacetic acid (5-HIAA) | 3-Methoxy-4-hydroxyphenylglycol (MHPG) | Dystrobrevin-binding protein 1 gene (DTNBP1) | DYSBINDIN DTNBP1 | PSYCHIATRY | SCHIZOPHRENIA | NEUROSCIENCES | PREFRONTAL CORTEX | CLINICAL NEUROLOGY | SANDY MICE | BLOC-1 | POLYMORPHISMS | DOPAMINE | PHARMACOLOGY & PHARMACY | SEROTONIN | RISK HAPLOTYPE | BRAIN | Gene Frequency | Humans | Neurotransmitter Agents - metabolism | Hydroxyindoleacetic Acid - cerebrospinal fluid | Genotype | Male | Hydroxyindoleacetic Acid - metabolism | Dystrophin-Associated Proteins | Genetic Variation | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Carrier Proteins - metabolism | Homovanillic Acid - metabolism | Norepinephrine - metabolism | Serotonin - metabolism | Methoxyhydroxyphenylglycol - metabolism | Female | Methoxyhydroxyphenylglycol - cerebrospinal fluid | Polymorphism, Single Nucleotide | Homovanillic Acid - cerebrospinal fluid | Dopamine - metabolism | Dysbindin | Metabolites | Genetic aspects | Protein binding | Genes | Medical and Health Sciences | Medicin och hälsovetenskap
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9. Full Text Pharmacokinetics of low molecular weight phenolic compounds in gerbil plasma after the consumption of calafate berry (Berberis microphylla) extract
by Bustamante, Luis and Pastene, Edgar and Duran-Sandoval, Daniel and Vergara, Carola and Von Baer, Dietrich and Mardones, Claudia
Food Chemistry, ISSN 0308-8146, 12/2018, Volume 268, pp. 347 - 354
Calafate is a berry with high concentration of anthocyanins and hydroxycinnamic acids that grows in South Patagonia. To date, no metabolism studies of phenolic... 
Plasma | Calafate | GC–MS | Berberis microphylla | Phenolic acid | Bioavailability | Pharmacokinetics | Syringic Acid (PubChem CID: 10742) | m-Coumaric Acid (PubChem CID: 637541) | Hydroquinone (PubChem CID: 785) | p-Coumaric Acid (PubChem CID: 637542) | Phenylacetic Acid (PubChem CID: 999) | Homovanillic Acid (PubChem CID: 1738) | 3,4-Dihydroxyphenylacetic Acid (PubChem CID: 547) | 3-Hydroxyphenylacetic Acid (PubChem CID: 12122) | Vanillic Acid (PubChem CID: 8468) | DIETARY POLYPHENOLS | HYDROXYCINNAMIC ACIDS | QUANTIFICATION | FOOD SCIENCE & TECHNOLOGY | ANTHOCYANINS | CHROMATOGRAPHY | MASS-SPECTROMETRY | GC-MS | NUTRITION & DIETETICS | METABOLISM | PRODUCTS | HEALTH | CHEMISTRY, APPLIED | Tandem Mass Spectrometry | Gerbillinae - metabolism | Animals | Molecular Weight | Berberis - chemistry | Fruit | Phenols - pharmacokinetics | Gerbillinae - blood | Anthocyanin | Auxin | Phenylacetic acid | Derivatives (Financial instruments) | Consumption data
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10. Full Text Analysis of vanillylmandelic acid and homovanillic acid by UPLC–MS/MS in serum for diagnostic testing for neuroblastoma
by Sadilkova, Katerina and Dugaw, Kathy and Benjamin, Denis and Jack, Rhona M
Clinica Chimica Acta, ISSN 0009-8981, 09/2013, Volume 424, pp. 253 - 257
Vanillylmandelic acid (VMA) and homovanillic acid (HVA) are typically measured in urine for the diagnosis and monitoring of neuroblastoma, a tumor in children... 
HVA | VMA | Neuroblastoma | Mass spectrometry | CATECHOLAMINE METABOLITES | PLASMA | URINE | MEDICAL LABORATORY TECHNOLOGY | TANDEM MASS-SPECTROMETRY | Reproducibility of Results | Chromatography, High Pressure Liquid - methods | Humans | Vanilmandelic Acid - urine | Neuroblastoma - blood | Child, Preschool | Infant | Reference Values | Neuroblastoma - diagnosis | Neuroblastoma - urine | Homovanillic Acid - blood | Sensitivity and Specificity | Homovanillic Acid - urine | Tandem Mass Spectrometry - methods | Vanilmandelic Acid - blood | Liquid chromatography | Diagnosis | Analysis
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11. Full Text Quantification of vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid in urine using a dilute-and-shoot and ultra-high pressure liquid chromatography tandem mass spectrometry method
by Grouzmann, Eric and Centeno, Catherine and Eugster, Philippe J
Clinical Chemistry and Laboratory Medicine (CCLM), ISSN 1434-6621, 08/2018, Volume 56, Issue 9, pp. 1533 - 1541
Background: Urinary vanillylmandelic acid (VMA) and homovanillic acid (HVA) are biomarkers for the diagnosis and follow-up of neuroblastoma, whereas urinary... 
5-hydroxyindoleacetic acid | carcinoid tumor | UHPLC-MS/MS | urine | dilute-and-shoot | neuroblastoma | vanillylmandelic acid | DIAGNOSIS | METABOLITES | MARKERS | ACETIC-ACID | REFERENCE INTERVALS | PLASMA | CLINICAL-CHEMISTRY | DISEASE | SEROTONIN | MEDICAL LABORATORY TECHNOLOGY | Urine | Spectroscopy | Electrochemical analysis | Ions | Mass spectroscopy | Liquid chromatography | Neuroblastoma | Assaying | Quadrupoles | Pressure | Chromatography | High pressure | Dilution | Sample preparation | Acids | Homovanillic acid | Linearity | Biomarkers | Electrochemistry | Sampling methods | Scientific imaging | Deuteration | Mass spectrometry | High performance liquid chromatography
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12. Full Text Tryptophan hydroxylase gene 1 ( TPH1 ) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers
by Andreou, Dimitrios and Saetre, Peter and Werge, Thomas and Andreassen, Ole A and Agartz, Ingrid and Sedvall, Göran C and Hall, Håkan and Terenius, Lars and Jönsson, Erik G and Medicinska fakulteten and Geriatrik and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för folkhälso- och vårdvetenskap
Psychiatry Research, ISSN 0165-1781, 2009, Volume 180, Issue 2, pp. 63 - 67
Abstract Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in serotonin synthesis. We investigated possible relationships between five TPH1 gene... 
Psychiatry | Genetics | Homovanillic acid (HVA) | Cerebrospinal fluid (CSF) | 5-hydroxyindoleacetic acid (5-HIAA) | 3-methoxy-4-hydroxyphenylglycol (MHPG) | NOREPINEPHRINE | PSYCHIATRY | 3-merhoxy-4-hydroxyphenylglycol (MHPG) | SCHIZOPHRENIA | INDIVIDUALS | MONOAMINE METABOLITE CONCENTRATIONS | POLYMORPHISMS | SEROTONIN LEVELS | CSF | DOPAMINE | SUICIDAL-BEHAVIOR | BRAIN | Young Adult | Genome-Wide Association Study | Gene Frequency | Humans | Adolescent | Indoles - cerebrospinal fluid | Adult | Female | Male | Polymorphism, Genetic - genetics | Homovanillic Acid - cerebrospinal fluid | Tryptophan Hydroxylase - genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | MEDICINE | Clinical Medicine | MEDICIN | Psykiatri
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13. Full Text Biological Evaluation of Natural and Synthesized Homovanillic Acid Esters as Inhibitors of Intestinal Fatty Acid Uptake in Differentiated Caco-2 Cells
by Lieder, B and Hans, J and Hentschel, F and Geissler, K and Ley, J
MOLECULES, ISSN 1420-3049, 10/2019, Volume 24, Issue 19, p. 3599
With raising prevalence of obesity, the regulation of human body fat is increasingly relevant. The modulation of fatty acid uptake by enterocytes represents a... 
homovanillic acid esters | CAPSINOIDS | Caco-2 cells | fatty acid uptake | BIOCHEMISTRY & MOLECULAR BIOLOGY | capsaicin | RECEPTOR | MECHANISMS | LINE CACO-2 | CHEMISTRY, MULTIDISCIPLINARY | obesity | capsiate | caco-2 cells
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14. Full Text The role of 3,4-dihydroxyphenylacetic acid adsorption in the oxidation of homovanillic acid at a glassy carbon rotating disc electrode
by Pfeifer, Rene and Tamiasso Martinhon, Priscila and Sousa, Celia and Moreira, Josino Costa and Nascimento, Marco Antonio Chaer and Barek, Jiří and Vyskočil, Vlastimil
Journal of Electroanalytical Chemistry, ISSN 1572-6657, 04/2019, Volume 838, pp. 129 - 135
Homovanillic acid (HVA) is an important biomarker for neurological disorders. Traditional methods for detection of this compound are chromatographic methods... 
Voltammetry | Rotating disc electrode | Homovanillic acid | 3,4-Dihydroxyphenylacetic acid | Electrochemical impedance spectroscopy | FLOW CELL | ELECTROCHEMISTRY | CHEMISTRY, ANALYTICAL | METABOLITES | CATECHOLAMINES | VANILLYLMANDELIC ACID | PERFORMANCE LIQUID-CHROMATOGRAPHY | URINE | PURIFICATION | DOPAMINE | INTERFERENCE | NEUROENDOCRINE TUMOR-MARKERS | Electrochemical reactions | Nervous system diseases | Adsorption | Resveratrol | Oxidation-reduction reaction | Mass spectrometry | Chromatography | Electric properties | Rotating disks | Surface chemistry | Fluorescence | Carbon | Rotation | Glassy carbon | Neurological diseases | Electrodes | Chemical reduction | Spectrometry | Acids | Potassium ferricyanide | Mathematical analysis | Biomarkers | Oxidation | Charge transfer | Diffusion | Electrochemical oxidation
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15. Full Text Correlative analysis of dopaminergic and serotonergic metabolism across the brain to study monoaminergic function and interaction
by Dellu-Hagedorn, Françoise and Fitoussi, Aurélie and De Deurwaerdère, Philippe
Journal of Neuroscience Methods, ISSN 0165-0270, 03/2017, Volume 280, pp. 54 - 63
The widespread innervation of dopamine (DA) and serotonin (5-HT) systems in cortical and subcortical regions suggests that their biochemical interactions can... 
Neurochemistry | Monoamine turnover | Correlation | Dopamine | Electrochemical detection | Serotonin | Amygdala | Rat | Linear regression | 3,4-Dihydroxyphenylacetic acid | Cortex | Monoamine | 5-Hydroxyindole-3-acetic acid | Connectomics | Nucleus accumbens | Striatum | Homovanillic acid | HPLC | Hippocampus | NEURONAL-ACTIVITY | QUANTAL SIZE | HOMOVANILLIC-ACID | REGIONS | MIDBRAIN | BIOCHEMICAL RESEARCH METHODS | NEUROSCIENCES | TRANSMISSION | ELECTRICAL-STIMULATION | DISEASE | CATECHOLAMINE METABOLISM | DORSAL RAPHE NUCLEUS | Brain - metabolism | 3,4-Dihydroxyphenylacetic Acid - metabolism | Animals | Homovanillic Acid - metabolism | Rats, Wistar | Serotonin - metabolism | Male | Hydroxyindoleacetic Acid - metabolism | Chromatography | Dopamine - metabolism | Physiological aspects | Brain | Neurosciences | Metabolites | Resveratrol | Liquid chromatography | Acetic acid | Organic acids
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16. Full Text A reliable and simple method for the assay of neuroendocrine tumor markers in human urine by solid-phase microextraction–gas chromatography-triple quadrupole mass spectrometry
by Monteleone, Marcello and Naccarato, Attilio and Sindona, Giovanni and Tagarelli, Antonio
Analytica Chimica Acta, ISSN 0003-2670, 01/2013, Volume 759, pp. 66 - 73
► A SPME–GC–QqQ MS approach was developed for the quantification of acidic biomarkers in human urine. ► The combined use of alkylchloroformate and SPME allows... 
Solid phase microextraction | 5-Hydroxyindoleacetic acid | Gas chromatography | Tandem mass spectrometry | Vanylmandelic acid | Homovanillic acid | CHEMISTRY, ANALYTICAL | METABOLITES | NEUROBLASTOMA | VANILLYLMANDELIC ACID | PERFORMANCE LIQUID-CHROMATOGRAPHY | ELECTROCHEMICAL DETECTION | HOMOVANILLIC-ACID | CARCINOID-TUMORS | CAPILLARY-ELECTROPHORESIS | FILTER-PAPER | Gas Chromatography-Mass Spectrometry - methods | Limit of Detection | Solid Phase Microextraction - methods | Humans | Vanilmandelic Acid - urine | Neuroendocrine Tumors - urine | Male | Gas Chromatography-Mass Spectrometry - economics | Biomarkers, Tumor - urine | Solid Phase Microextraction - economics | Adult | Female | Hydroxyindoleacetic Acid - urine | Homovanillic Acid - urine | Mass spectrometry | Methods | Chromatography | Tumors
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