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The Journal of Physical Chemistry B, ISSN 1520-6106, 07/2007, Volume 111, Issue 27, pp. 7897 - 7913
A mathematical model is presented of the kinetics of non-native protein aggregation that combines Lumry−Eyring and nucleated polymerization (LENP)... 
FIBRIL FORMATION | HUMAN-FACTOR-VIII | BETA-AMYLOID AGGREGATION | TRANSTHYRETIN | MECHANISM | SHELF-LIFE | DISEASE | CHEMISTRY, PHYSICAL | THERMAL AGGREGATION | AQUEOUS-SOLUTION | PREDICTION | Thermodynamics | Algorithms | Molecular Weight | Models, Chemical | Half-Life | Protein Conformation | Kinetics | Models, Statistical | Proteins - chemistry | Protein Folding
Journal Article
Journal Article
Nature, ISSN 0028-0836, 07/2015, Volume 523, Issue 7562, pp. 607 - 611
The human lens is comprised largely of crystallin proteins assembled into a highly ordered, interactive macro-structure essential for lens transparency and... 
SELENITE-INDUCED CATARACTOGENESIS | MULTIDISCIPLINARY SCIENCES | MUTATION | PREVENTION | ALPHA-B-CRYSTALLIN | DOMINANT CONGENITAL CATARACT | HUMAN OXIDOSQUALENE CYCLASE | SEQUENCING DATA | CHINESE FAMILY | LENS | EXPRESSION | Crystallins - metabolism | Humans | Cataract - pathology | Molecular Sequence Data | Lanosterol - pharmacology | Male | Amyloid - chemistry | Amyloid - ultrastructure | Lens, Crystalline - pathology | Mutant Proteins - ultrastructure | Amyloid - metabolism | Protein Aggregation, Pathological - pathology | Base Sequence | Amyloid - drug effects | Adult | Female | Child | Crystallins - chemistry | Protein Aggregates - drug effects | Amino Acid Sequence | Cell Line | Crystallins - ultrastructure | Lanosterol - administration & dosage | Mutant Proteins - genetics | Lens, Crystalline - metabolism | Models, Molecular | Mutant Proteins - metabolism | Crystallins - genetics | Cataract - metabolism | Lanosterol - therapeutic use | Protein Aggregation, Pathological - drug therapy | Animals | Cataract - congenital | Pedigree | Mutant Proteins - chemistry | Dogs | Cataract - genetics | Cataract - drug therapy | Lens, Crystalline - drug effects | Proteins | Cataract | Physiological aspects | Development and progression | Genetic aspects | Research | Gene expression | Drug therapy | Cataracts | Studies | Older people | Mortality | Mutation | Cholesterol
Journal Article
Analytical Chemistry, ISSN 0003-2700, 09/2017, Volume 89, Issue 17, pp. 9322 - 9329
Journal Article