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EMBO Molecular Medicine, ISSN 1757-4676, 05/2011, Volume 3, Issue 5, pp. 266 - 278
Journal Article
CHEMPHYSCHEM, ISSN 1439-4235, 06/2017, Volume 18, Issue 12, pp. 1493 - 1498
Nuclear spin hyperpolarization techniques are revolutionizing the field of C-13 molecular MRI. While dissolution dynamic nuclear polarization (d-DNP) is... 
NMR SIGNAL AMPLIFICATION | PARA-HYDROGEN | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | SPIN HYPERPOLARIZATION | CHEMISTRY, PHYSICAL | parahydrogen | CANCER | NMR | N-15 HYPERPOLARIZATION | METABOLISM | spectroscopy | INDUCED POLARIZATION | IN-VIVO | SABRE | MAGNETIC-RESONANCE | hyperpolarization | carbon-13
Journal Article
Neuropharmacology, ISSN 0028-3908, 08/2018, Volume 138, pp. 20 - 31
Although a number of experimental and clinical studies have shown that hypoxia typically accompanies acute inflammatory responses, the combinatorial effect of... 
Hypoxia | Inflammation | Hyperpolarization-activated cation current (Ih) | Reoxygenation | Synaptic transmission | Hyperexcitability | Hyperpolarization-activated cation current (I | SENSITIVE POTASSIUM CHANNELS | NEUROTRANSMITTER RELEASE | ACETYLCHOLINE-RELEASE | AMPA RECEPTOR | NEUROSCIENCES | POSTHYPOXIC HYPEREXCITABILITY | IN-VITRO | PYRAMIDAL NEURONS | Hyperpolarization-activated cation current (I-h) | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | RAT HIPPOCAMPUS | CEREBRAL-ISCHEMIA | Membrane Potentials - drug effects | Synapses - drug effects | Hypoxia - drug therapy | Synaptic Transmission - physiology | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - metabolism | Synapses - physiology | Tissue Culture Techniques | Hypoxia - complications | Benzazepines - pharmacology | Membrane Potentials - physiology | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - antagonists & inhibitors | Rats, Sprague-Dawley | CA1 Region, Hippocampal - drug effects | Oxygen - metabolism | Inflammation - complications | Animals | Inflammation - drug therapy | Central Nervous System Agents - pharmacology | Neurons - physiology | Hypoxia - physiopathology | Synaptic Transmission - drug effects | CA1 Region, Hippocampal - physiopathology | Neurons - drug effects | Inflammation - physiopathology | Medicine, Experimental | Brain | Medical research | Neurons | Injuries | Index Medicus
Journal Article
Angewandte Chemie - International Edition, ISSN 1433-7851, 01/2019, Volume 58, Issue 5, pp. 1334 - 1339
Free radicals generated by UV-light irradiation of a frozen solution containing a fraction of pyruvic acid (PA) have demonstrated their dissolution dynamic... 
glucose | hyperpolarization | radicals | NMR spectroscopy
Journal Article
Journal of Magnetic Resonance, ISSN 1090-7807, 09/2019, Volume 306, pp. 124 - 127
Hyperpolarized MR by dissolution Dynamic Nuclear Polarization (dDNP) appeared on the scene in 2003. Since then, it has been translated to the clinic and... 
Dissolution-DNP | Hyperpolarization | Hyperpolarized MR
Journal Article
Journal of Physical Chemistry A, ISSN 1089-5639, 12/2017, Volume 121, Issue 48, pp. 9221 - 9228
Optimal efficiency of dissolution dynamic nuclear polarization (DNP) is essential to provide the required high sensitivity enhancements for in vitro and in... 
NMR | EPR | Hyperpolarization | DNP
Journal Article
Bulletin of Experimental Biology and Medicine, ISSN 0007-4888, 09/2019, pp. 1 - 4
The study examined the effects of hyperpolarization-activated funny current (If) on HR and coronary flow in Langendorff-isolated hearts from newborn rats.... 
Heart | Rodents | Hyperpolarization
Journal Article
ChemPhysChem, ISSN 1439-4235, 10/2018, Volume 19, Issue 20, pp. 2598 - 2598
The Front Cover illustrates the hyperpolarization of bulk water in a recently established catalytic system. It is called NEPTUN (nuclear exchange polarization... 
NMR | parahydrogen | water | Hyperpolarization | NEPTUN
Journal Article
Journal of Magnetic Resonance, ISSN 1090-7807, 04/2016, Volume 265, pp. 59 - 66
SABRE (Signal Amplification By Reversible Exchange) nuclear spin hyperpolarization method can provide strongly enhanced NMR signals as a result of the... 
J-modulation | Hyperpolarization | SABRE
Journal Article
Journal of Physical Chemistry Letters, ISSN 1948-7185, 10/2018, Volume 9, Issue 20, pp. 6136 - 6142
Journal Article
CHEMISTRY-A EUROPEAN JOURNAL, ISSN 0947-6539, 12/2017, Volume 23, Issue 67, pp. 16990 - 16990
Despite the successful use of isoniazid, rifampicin, pyrazinamide and ethambutol in the treatment of tuberculosis (TB), it is a disease of growing global... 
MYCOBACTERIUM-TUBERCULOSIS | PARA-HYDROGEN | tuberculosis | REVERSIBLE EXCHANGE CATALYSIS | SPIN HYPERPOLARIZATION | catalysis | CHEMISTRY, MULTIDISCIPLINARY | PYRAZINOIC ACID-ESTERS | SIGNAL AMPLIFICATION | N-15 HYPERPOLARIZATION | isotopes | SABRE | VITRO ANTIMYCOBACTERIAL ACTIVITY | LOW MAGNETIC-FIELD | hyperpolarization | POLARIZATION TRANSFER
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2017, Volume 114, Issue 16, pp. E3188 - E3194
Hyperpolarization turns typically weak NMR and MRI responses into strong signals so that ordinarily impractical measurements become possible. The potential to... 
NMR | Catalysis | MRI | Hyperpolarization | SABRE | Physical Sciences | PNAS Plus | catalysis | hyperpolarization
Journal Article
Circulation Research, ISSN 0009-7330, 10/2017, Volume 121, Issue 9, pp. 1058 - 1068
RATIONALE:Downregulation of the pacemaking ion channel, HCN4 (hyperpolarization-activated cyclic nucleotide gated channel 4), and the corresponding ionic... 
sinoatrial node | ion channel remodeling | athletes | micro-RNAs | sinus bradycardia | exercise training | CARDIAC & CARDIOVASCULAR SYSTEMS | INTRONIC MICRORNAS | HEART-FAILURE | DOWN-REGULATION | O-GLCNAC TRANSFERASE | HIGH VAGAL TONE | ATRIAL-FIBRILLATION | HOST GENES | ENDURANCE EXERCISE | PERIPHERAL VASCULAR DISEASE | CARDIOMYOCYTE DIFFERENTIATION | HEMATOLOGY | Gene Targeting - methods | Bradycardia - genetics | Humans | Physical Conditioning, Animal - methods | Male | MicroRNAs - metabolism | Gene Knockdown Techniques - methods | Potassium Channels - metabolism | Young Adult | Bradycardia - metabolism | Muscle Proteins - metabolism | Adult | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - metabolism | Mice, Inbred C57BL | Sinoatrial Node - physiopathology | Bradycardia - physiopathology | Physical Conditioning, Animal - physiology | Potassium Channels - genetics | Muscle Proteins - genetics | Animals | Adolescent | Sinoatrial Node - metabolism | Exercise - physiology | Mice | MicroRNAs - genetics | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - genetics | Bradycardia | Exercise | Physiological aspects | Ion channels | Research | Nucleotide sequencing | Athletes | Health aspects | Risk factors | DNA sequencing | Cardiac arrhythmia | Animal models | Physical training | MiRNA | Reverse transcription | Polymerase chain reaction | Heart rate | Sinuses | Sinus | Computer applications | Fitness training programs | Nkx2.5 protein | Hyperpolarization | Ion channels (cyclic nucleotide-gated) | Index Medicus | 10063 | 10032 | 10035 | Molecular Medicine | 10001 | 10003
Journal Article
Neuroscience, ISSN 0306-4522, 2015, Volume 305, pp. 279 - 292
Highlights • Intrafrontal cortex injection of Aβ caused deficits in passive avoidance task. • Aβ treatment decreased excitability of CA1 pyramidal cells. •... 
Neurology | amyloid β (Aβ) | intrinsic excitability | CA1 pyramidal neurons | Ih channel current | Intrinsic excitability | Amyloid β (Aβ) | HYPERPOLARIZATION-ACTIVATED CURRENT | SYNAPTIC DYSFUNCTION | ALZHEIMERS-DISEASE | H-CHANNELS | NEUROSCIENCES | PREFRONTAL CORTEX | CORTICAL EXCITABILITY | POTENTIAL VANILLOID 1 | LONG-TERM DEPRESSION | MOUSE MODEL | amyloid beta (A beta) | HIPPOCAMPAL INTERNEURONS | Alzheimer Disease - complications | Pyrimidines - agonists | Rats, Wistar | Capsaicin - pharmacology | Male | Nerve Net - drug effects | Nerve Net - physiology | Alzheimer Disease - pathology | Sensory System Agents - pharmacology | CA1 Region, Hippocampal - pathology | TRPV Cation Channels - antagonists & inhibitors | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - agonists | Neurons - physiology | Alzheimer Disease - chemically induced | Neurons - drug effects | Disease Models, Animal | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - metabolism | Amyloid beta-Peptides - toxicity | TRPV Cation Channels - agonists | Rats | Capsaicin - analogs & derivatives | Avoidance Learning - physiology | Pyrimidines - pharmacology | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - antagonists & inhibitors | Patch-Clamp Techniques | Animals | Memory Disorders - etiology | Avoidance Learning - drug effects | In Vitro Techniques | Neurons | Index Medicus
Journal Article