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Cell Reports, ISSN 2211-1247, 06/2012, Volume 1, Issue 6, pp. 703 - 714
To model human neural-cell-fate specification and to provide cells for regenerative therapies, we have developed a method to generate human neural progenitors... 
HUMAN ES | IN-VITRO | VENTRAL MESENCEPHALON | FLOOR PLATE | MIDBRAIN DOPAMINE NEURONS | SUBSTANTIA-NIGRA | RAT MODEL | LINES | PARKINSONS-DISEASE | IPS CELLS | CELL BIOLOGY | Body Patterning - drug effects | Organ Specificity - drug effects | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Humans | Cell Survival - genetics | Motor Activity - drug effects | Neurons - cytology | Neural Stem Cells - cytology | Cell Culture Techniques - methods | Cell Lineage - drug effects | Neural Tube - drug effects | Cell Differentiation - genetics | Organ Specificity - genetics | Dopamine - secretion | Dopaminergic Neurons - metabolism | Telencephalon - drug effects | Dopaminergic Neurons - drug effects | Neural Stem Cells - transplantation | Neurons - metabolism | Neurons - drug effects | Cell Lineage - genetics | Cell Survival - drug effects | Telencephalon - metabolism | Telencephalon - cytology | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Cells, Cultured | Neural Stem Cells - drug effects | Rats | Glycogen Synthase Kinase 3 - metabolism | Aging - pathology | Gene Expression Regulation - drug effects | Phenotype | Animals | Wnt Signaling Pathway - drug effects | Embryonic Stem Cells - drug effects | Wnt Signaling Pathway - genetics | Cell Differentiation - drug effects | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Neural Tube - embryology | Body Patterning - genetics | Neural Stem Cells - metabolism | Electrophysiological Phenomena - drug effects | Index Medicus | Biological Sciences | Biologi | Naturvetenskap | Cellbiologi | Natural Sciences | Cell Biology
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2016, Volume 113, Issue 3, pp. E291 - E299
Protein transduction domains (PTDs) are powerful nongenetic tools that allow intracellular delivery of conjugated cargoes to modify cell behavior. Their use in... 
Human embryonic stem cells | Transduction | Cell-penetrating peptides | Differentiation | Heparin-binding domain | differentiation | transduction | MULTIDISCIPLINARY SCIENCES | MECHANISMS | HEPARIN | MAMMALIAN-CELLS | IPS CELLS | PLURIPOTENT STEM-CELLS | cell-penetrating peptides | heparin-binding domain | MACROPINOCYTOSIS | GROWTH-FACTOR | PROTEINS | human embryonic stem cells | NIH 3T3 Cells | Homeodomain Proteins - metabolism | Human Embryonic Stem Cells - cytology | Humans | Mouse Embryonic Stem Cells - cytology | Mouse Embryonic Stem Cells - drug effects | Mouse Embryonic Stem Cells - metabolism | Drug Delivery Systems | Nanoparticles | Human Embryonic Stem Cells - drug effects | Integrases - metabolism | Cell Membrane - metabolism | Cell Membrane - drug effects | Cell-Penetrating Peptides - chemistry | Induced Pluripotent Stem Cells - metabolism | Protein Structure, Tertiary | Detergents - pharmacology | Human Embryonic Stem Cells - metabolism | Nanog Homeobox Protein | Induced Pluripotent Stem Cells - drug effects | Glycosaminoglycans - metabolism | Endocytosis - drug effects | Solubility | MyoD Protein - metabolism | Nucleic Acids - metabolism | Trypsin - metabolism | Amino Acid Motifs | Animals | Muscle Development - drug effects | Cell Differentiation - drug effects | Cell Proliferation - drug effects | Mice | Genome | Cell-Penetrating Peptides - metabolism | Physiological aspects | Physiological research | Cellular signal transduction | Glycosaminoglycans | Research | Proteins | Peptides | Cytoplasm | Binding sites | Stem cells | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2014, Volume 111, Issue 34, pp. 12426 - 12431
Pluripotency can be induced in somatic cells by overexpressing transcription factors, including POU class 5 homeobox 1 (OCT3/4), sex determining region Y-box 2... 
Phenotypes | Induced pluripotent stem cells | Somatic cells | Stem cells | Retroviridae | Embryonic stem cells | Pluripotent stem cells | Cellular differentiation | Cells | Mesenchymal stem cells | Epigenetics | Retrotransposon | Evolution | NONCODING RNA-ROR | ROADBLOCK | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | TRANSPOSABLE ELEMENTS | evolution | INDUCTION | epigenetics | IPS CELLS | PLURIPOTENT STEM-CELLS | PATHWAY | HUMAN FIBROBLASTS | retrotransposon | EXPRESSION | Octamer Transcription Factor-3 - physiology | Endogenous Retroviruses - physiology | Embryonic Stem Cells - cytology | Epigenesis, Genetic | Humans | Endogenous Retroviruses - genetics | Pluripotent Stem Cells - virology | Gene Knockdown Techniques | Octamer Transcription Factor-3 - genetics | Cell Differentiation - genetics | RNA, Viral - antagonists & inhibitors | RNA, Viral - genetics | SOXB1 Transcription Factors - genetics | Embryonic Stem Cells - virology | SOXB1 Transcription Factors - physiology | Induced Pluripotent Stem Cells - cytology | Cell Differentiation - physiology | Cellular Reprogramming - genetics | Gene Expression | Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - physiology | Induced Pluripotent Stem Cells - virology | Pluripotent Stem Cells - physiology | Kruppel-Like Transcription Factors - physiology | RNA, Long Noncoding - genetics | Embryonic Stem Cells - physiology | RNA, Long Noncoding - antagonists & inhibitors | Kruppel-Like Transcription Factors - genetics | Cellular Reprogramming - physiology | Epigenetic inheritance | Transcription factors | Retroviruses | Physiological aspects | Genetic research | Genetic aspects | Research | Cell differentiation | Gene expression | Virus research | Viruses | Ribonucleic acid--RNA | Index Medicus | Biological Sciences
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2014, Volume 77, Issue Jul 16, pp. 266 - 275
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 08/2013, Volume 438, Issue 1, pp. 13 - 19
Journal Article
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 2011, Volume 7, Issue 1, pp. 550 - n/a
Assessing relevant molecular differences between human‐induced pluripotent stem cells (hiPSCs) and human embryonic stem cells (hESCs) is important, given that... 
proteomics | human‐induced pluripotent stem cells | quantitation | human embryonic stem cells | human-induced pluripotent stem cells | DEFINED FACTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | PROTEIN-INTERACTION NETWORK | LINES | IPS CELLS | COPY NUMBER | HUMAN FIBROBLASTS | HUMAN SOMATIC-CELLS | ES CELLS | GENE-EXPRESSION SIGNATURES | Pluripotent Stem Cells - metabolism | Cell Line | Embryonic Stem Cells - metabolism | Proteome - genetics | Embryonic Stem Cells - cytology | Pluripotent Stem Cells - cytology | Oligonucleotide Array Sequence Analysis | Humans | Mass Spectrometry | Gene Expression Profiling - methods | Proteome - analysis | Proteome - metabolism | Biotechnology | Animal models | Similarity | Transcription | Peptides | Gene regulation | Embryo cells | Antigen processing | Stem cell transplantation | Electron transfer | Genomes | Experiments | Proteins | Precursors | Cell adhesion | Fibroblasts | Complementation | Cation exchange | Antigens | Fractionation | Mass spectroscopy | Cation exchanging | Abundance | Embryo fibroblasts | Metabolism | Gene expression | Embryos | Adhesion | Molecular chains | Hip | Studies | Organic chemistry | Analogies | Ethical standards | Somatic cells | Proteomics | Cell lines | Stem cells | Energy of dissociation | Differentiation | Mass spectrometry | Pluripotency | Inhibitory postsynaptic potentials | Index Medicus
Journal Article
Altex, ISSN 1868-596X, 2017, Volume 34, Issue 1, pp. 95 - 132
Journal Article
Diabetologia, ISSN 0012-186X, 8/2017, Volume 60, Issue 8, pp. 1454 - 1466
Pancreatic beta-like cells generated from human induced pluripotent stem cells (hiPSCs) or human embryonic stem cells (hESCs) offer an appealing donor tissue... 
BMP4 | Medicine & Public Health | Human Physiology | Metabolic Diseases | Beta-like cells | Sodium cromoglicate | Internal Medicine | Insulin–neurogenin 3 | Small molecule | Human iPSC | PROGENITOR CELLS | ANTIALLERGIC DRUGS | HUMAN IPS CELLS | BETA-CELLS | MAST-CELLS | Insulin-neurogenin 3 | PLURIPOTENT STEM-CELLS | ISLET TRANSPLANTATION | IN-VITRO | DISODIUM-CROMOGLYCATE | ENDOCRINOLOGY & METABOLISM | INSULIN-PRODUCING CELLS | Embryonic Stem Cells - metabolism | Induced Pluripotent Stem Cells - drug effects | Homeodomain Proteins - metabolism | Humans | Pancreas - cytology | Male | Pancreas - metabolism | Bone Morphogenetic Protein 4 - metabolism | Insulin-Secreting Cells - metabolism | Animals | Cromolyn Sodium - pharmacology | Embryonic Stem Cells - drug effects | Insulin-Secreting Cells - drug effects | Cell Differentiation - drug effects | Trans-Activators - metabolism | Insulin-Secreting Cells - cytology | Mice | Induced Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - metabolism | Embryonic stem cells | Bone morphogenetic proteins | Analysis | Explants | Cell culture | Bone morphogenetic protein 4 | Embryo cells | Stem cell transplantation | Gene expression | Ribonucleic acid--RNA | Insulin | Neurogenin 3 | Neurogenin | Homeobox | Sodium | Rodents | Stem cells | Pancreas | Growth factors | Pluripotency | Inhibitory postsynaptic potentials | Index Medicus
Journal Article
Stem Cells, ISSN 1066-5099, 10/2009, Volume 27, Issue 10, pp. 2427 - 2434
Human induced pluripotent stem cells (iPSCs) have great promise for cellular therapy, but it is unclear if they have the same potential as human embryonic stem... 
Retinal pigmented epithelium | Age-related macular degeneration | Induced pluripotent stem cells | Retinitis pigmentosa | ISOMEROHYDROLASE | ROD OUTER SEGMENTS | PHAGOCYTOSIS | MACULAR DEGENERATION | retinal pigmented epithelium | IPS CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | MICROSOMAL PROTEIN | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | retinitis pigmentosa | induced pluripotent stem cells | RPE CELLS | DIFFERENTIATION | HEMATOLOGY | age-related macular degeneration | EYE DEVELOPMENT | EXPRESSION | Retinal Pigment Epithelium - metabolism | Cell Proliferation | Homeodomain Proteins - metabolism | Humans | Nerve Tissue Proteins - analysis | Retinal Diseases - therapy | RNA, Messenger - analysis | Retinal Rod Photoreceptor Cells - metabolism | RNA, Messenger - metabolism | SOXB1 Transcription Factors - metabolism | SOXB1 Transcription Factors - pharmacology | Homeodomain Proteins - pharmacology | Cell Differentiation - physiology | Integrin alphaV - metabolism | Biomarkers - metabolism | Cell Line | Nanog Homeobox Protein | Pluripotent Stem Cells - cytology | Biomarkers - analysis | Octamer Transcription Factor-3 - pharmacology | Phagocytosis - physiology | Regeneration - physiology | Nerve Tissue Proteins - metabolism | Pluripotent Stem Cells - metabolism | Phenotype | Regeneration - drug effects | Cell Differentiation - drug effects | Octamer Transcription Factor-3 - metabolism | Pluripotent Stem Cells - drug effects | Retinal Rod Photoreceptor Cells - cytology | Cell Polarity - physiology | Brain Tissue Transplantation - methods | Retinal Pigment Epithelium - cytology | Index Medicus
Journal Article