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Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 11/2017, Volume 37, Issue 11, pp. 2007 - 2013
Platelets, derived from megakaryocytes, are anucleate cytoplasmic discs that circulate in the blood stream and play major roles in hemostasis, inflammation,... 
hematopoiesis | iPSC | megakaryocyte | platelet
Journal Article
Journal of pharmacological sciences, ISSN 1347-8613, 05/2019
Using bright-field images of cultured human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), we trained a convolutional neural network (CNN),... 
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 05/2008, Volume 28, Issue 20, pp. 5189 - 5194
Central sensitization, increased sensitivity in spinal cord dorsal horn neurons after injuries, plays an essential role in the induction and maintenance of... 
Disinhibition | Soluble IL-6 receptor | IPSC | GABA | EPSC | Proinflammatory cytokines | Glycine | PICs | proinflammatory cytokines (PICs) | soluble IL-6 receptor | glycine | Excitatory postsynaptic current (EPSC) | inhibitory postsynaptic current (IPSC) | dis-inhibition
Journal Article
Journal Article
Current Protocols in Cell Biology, ISSN 1934-2500, 06/2018, Volume 79, Issue 1, p. e51
Accurate modeling of human neuronal cell biology has been a long-standing challenge. However, methods to differentiate human induced pluripotent stem cells... 
transcription factor–mediated differentiation | LMN | Neurons | iPSC-derived neurons | iPSC
Journal Article
11/2012
MicroRNAs (miRNAs) are a newly identified class of small regulatory non-coding endogenous RNAs that take part in a series of important processes by regulating... 
iPSCs | miRNAs detection | miRNAs | ESCs
Web Resource
Translational Neurodegeneration, ISSN 2047-9158, 12/2019, Volume 8, Issue 1, pp. 1 - 13
Abstract Background Since the discovery of the induced pluripotent stem cell (iPSC) technique more than a decade ago, extensive progress has been made to... 
iPSC-derived microglia | Disease modeling | Alzheimer’s disease | iPSC-derived astrocytes | Induced pluripotent stem cells | iPSC-derived neurons
Journal Article
Toxicology in Vitro, ISSN 0887-2333, 09/2015, Volume 29, Issue 6, pp. 1217 - 1221
In 1959 Russell and Burch stated that “Mammalian tissue cultures have become one of the most important replacement techniques”. Although they would likely be... 
Omics | Stem cells | iPSC
Journal Article
The Journal of Neuroscience, ISSN 0270-6474, 09/2018, Volume 38, Issue 38, pp. 8128 - 8145
Two major GABAA receptor classes mediate ionotropic GABA signaling, those containing a δ subunit and those with a γ2 subunit. The classical viewpoint equates... 
GABA | inhibition | tonic | hippocampus | IPSC | picrotoxin
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 07/2017, Volume 108, pp. S89 - S89
Journal Article
ACS Nano, ISSN 1936-0851, 07/2016, Volume 10, Issue 7, pp. 6563 - 6573
Induced pluripotent stem cells (iPSCs) have the ability to differentiate into any specialized somatic cell type, which makes them an attractive tool for a wide... 
iPSC colony morphology | carrier uptake | virus particle | LbL carrier | liposome | iPSC | Index Medicus
Journal Article
Neuroscience, ISSN 0306-4522, 2016, Volume 340, pp. 48 - 61
Highlights • α4β2∗ nAChRs stimulate IPSCs in FS interneurons, in layer V of the mouse PFC (Fr2). • In P16-P63 mice, nicotine increased both IPSC and mIPSC... 
Neurology | heteromeric nAChR | interneuron | PFC | IPSC | parvalbumin | somatostatin | Immunohistochemistry | Receptors, Nicotinic - metabolism | Tissue Culture Techniques | gamma-Aminobutyric Acid - metabolism | Aging - drug effects | Inhibitory Postsynaptic Potentials - physiology | Parvalbumins - metabolism | Male | Miniature Postsynaptic Potentials - drug effects | Microscopy, Confocal | Patch-Clamp Techniques | Animals | Prefrontal Cortex - drug effects | Neurotransmitter Agents - pharmacology | Prefrontal Cortex - metabolism | Female | Mice | Neurons - metabolism | Neurons - drug effects | Somatostatin - metabolism | Inhibitory Postsynaptic Potentials - drug effects | Aging - metabolism | Miniature Postsynaptic Potentials - physiology | Index Medicus | VGAT, vesicular GABA transporter | Vrest, resting membrane potential | IPSC, inhibitory postsynaptic current | mIPSC, miniature IPSC | DHβE, dihydro-β-erythroidine | NS, not significantly different | Fr2, frontal area 2 | TTX, tetrodotoxin | PV, parvalbumin | AHP, after-hyperpolarization | MLA, methyllycaconitine | ADNFLE, autosomal dominant nocturnal frontal lobe epilepsy | AP5, d(−)-2-amino-5-phosphono-pentanoic acid | FS, fast-spiking | SOM, somatostatin | BSA, bovine serum albumin | nAChR, nicotinic acetylcholine receptor | PBS, phosphate buffered saline | AP, action potential | DF, degrees of freedom | Rin, input resistance | ACh, acetylcholine | KS, Kolmogorov–Smirnov | CNQX, 6-cyano-7-nitroquinoxaline-2,3-dione | 5-IA, 5-iodo-3-[2(S)-azetidinylmethoxy]pyridine | PFC, prefrontal cortex
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2017, Volume 81, Issue 10, pp. S344 - S344
Journal Article
STEM CELLS, ISSN 1066-5099, 10/2010, Volume 28, Issue 10, pp. 1728 - 1740
Journal Article
Journal of Neurophysiology, ISSN 0022-3077, 03/2012, Volume 107, Issue 5, pp. 1431 - 1442
Journal Article
CANCER SCIENCE, ISSN 1349-7006, 01/2018, Volume 109, pp. 758 - 758
Conference Proceeding
Journal of Cell Science, ISSN 0021-9533, 2015, Volume 128, Issue 1, pp. 81 - 87
Journal Article
Cell Cycle, ISSN 1538-4101, 10/2019, Volume 18, Issue 19, pp. 2495 - 2508
Children with Hutchinson-Gilford progeria syndrome (HGPS) succumb to myocardial infarction and stroke in their teen years. Endothelial dysfunction is an early... 
endothelium | endothelial cells | Progeria | telomeres | iPSC | dysfunction | Index Medicus
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2019, Volume 1919, pp. 175 - 186
Limited access to primary tissue from various nonhuman primate (NHP) species represents a significant unmet need that hampers progress in understanding unique... 
Marmoset iPSCs | iPSC characterization | Scorecard | Regenerative medicine | Nonhuman primate iPSCs | Pluripotency | Index Medicus
Journal Article
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