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index medicus (43) 43
immunology (33) 33
t-lymphocytes, regulatory - immunology (29) 29
itreg (27) 27
humans (26) 26
animals (25) 25
foxp3 (21) 21
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t cells (17) 17
t-lymphocytes, regulatory - metabolism (15) 15
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chemical and pharmacologic phenomena (13) 13
expression (13) 13
article (12) 12
induction (11) 11
lymphocytes (11) 11
hemic and immune systems (10) 10
mice, inbred c57bl (10) 10
regulatory t-cells (10) 10
tgf-beta (10) 10
cell biology (9) 9
cells, cultured (9) 9
generation (9) 9
itregs (9) 9
lymphocytes t (9) 9
regulatory t cells (9) 9
t-lymphocytes, regulatory - cytology (9) 9
cd4 antigen (8) 8
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female (8) 8
immunoregulation (8) 8
activation (7) 7
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differentiation (7) 7
forkhead transcription factors - immunology (7) 7
foxp3 protein (7) 7
in-vivo (7) 7
male (7) 7
signal transduction (7) 7
tolerance (7) 7
allergy and immunology (6) 6
apoptosis (6) 6
cell proliferation (6) 6
colitis (6) 6
cutting edge (6) 6
adult (5) 5
autoimmunity (5) 5
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cell line (5) 5
cytokines (5) 5
flow cytometry (5) 5
forkhead transcription factors - genetics (5) 5
hematology (5) 5
immunotherapy (5) 5
inflammation (5) 5
interleukin-2 receptor alpha subunit - immunology (5) 5
mice, inbred balb c (5) 5
mice, knockout (5) 5
ntreg (5) 5
oncology (5) 5
t-lymphocyte subsets - immunology (5) 5
t-lymphocytes, regulatory - drug effects (5) 5
treg (5) 5
antigen (4) 4
antigens, cd - immunology (4) 4
biology (4) 4
cell differentiation (4) 4
cell differentiation - immunology (4) 4
dendritic cells - immunology (4) 4
growth-factor-beta (4) 4
ifn-gamma (4) 4
immune tolerance - immunology (4) 4
immunosuppression (4) 4
in-vitro (4) 4
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interleukin 10 (4) 4
lymphocyte activation - immunology (4) 4
medicine, research & experimental (4) 4
middle aged (4) 4
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regulatory t cell (4) 4
retinoic-acid (4) 4
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transcription factor foxp3 (4) 4
treg cells (4) 4
young adult (4) 4
abridged index medicus (3) 3
aged (3) 3
allergy (3) 3
antigens, cd - metabolism (3) 3
biochemistry & molecular biology (3) 3
biological response modifiers (3) 3
biotechnology & applied microbiology (3) 3
cd25 (3) 3
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Journal Article
Leukemia, ISSN 0887-6924, 02/2019, Volume 33, Issue 2, pp. 426 - 438
We investigate here how APRIL impacts immune regulatory T cells and directly contributes to the immunosuppressive multiple myeloma (MM) bone marrow (BM)... 
B-CELLS | BAFF | MATURATION ANTIGEN | IMMUNE STATUS | MICROENVIRONMENT | ONCOLOGY | BONE-MARROW | GROWTH | BCMA | CHIMERIC ANTIGEN RECEPTOR | HEMATOLOGY | PLASMA-CELLS | Signal Transduction | Antibodies, Monoclonal - pharmacology | Humans | Cells, Cultured | Gene Expression Regulation, Neoplastic | Multiple Myeloma - immunology | Multiple Myeloma - metabolism | Osteoclasts - cytology | Osteoclasts - metabolism | Tumor Necrosis Factor Ligand Superfamily Member 13 - metabolism | T-Lymphocytes, Regulatory - immunology | Transmembrane Activator and CAML Interactor Protein - metabolism | Transmembrane Activator and CAML Interactor Protein - genetics | Immunosuppression | Multiple Myeloma - drug therapy | Osteoclasts - immunology | Immune Tolerance - immunology | Biomarkers, Tumor - metabolism | Tumor Necrosis Factor Ligand Superfamily Member 13 - genetics | Biomarkers, Tumor - genetics | Immunosuppressive Agents - pharmacology | Osteoclasts - drug effects | Cell survival | Immunoregulation | Multiple myeloma | Lymphocytes T | Survival | Patients | APRIL protein | Signaling | CTLA-4 protein | Biomedical materials | Lymphocytes B | Lymphocytes | PD-L1 protein | Interleukin 10 | Cell cycle | Bone marrow | Monoclonal antibodies | Foxp3 protein | Biocompatibility | Osteoclasts | Combined treatment | Apoptosis | regulatory T (Treg) | TGFβ | Transmembrane Activator and CAML Interactor (TACI) | tumor growth factor beta | Osteoclast (OC) | multiple myeloma (MM) | interleukin-10 | A proliferation inducing ligand (APRIL) | conventional T (Tcon) | IL-10 | tumor-induced Treg (iTregs)
Journal Article
Journal Article
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2011, Volume 38, Issue 1, pp. 59 - 69
Abstract The Bcl-2 regulated apoptosis pathway is critical for the elimination of autoreactive lymphocytes, thereby precluding autoimmunity. T cells escaping... 
Allergy and Immunology | Bcl-2 | Autoimmunity | Regulatory T cells | Bim | Apoptosis | ACTIVATION | IMMUNOLOGY | SUPPRESSION | RESPONSES | CD4(+)CD25(+) | FOXP3(+) | EXPRESSION | T-CELLS | BH3-ONLY PROTEINS | TRANSGENIC MICE | T-Lymphocytes, Regulatory - metabolism | Cell Survival - genetics | Apoptosis - genetics | Male | Gene Expression Profiling | Green Fluorescent Proteins - genetics | Inflammatory Bowel Diseases - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Flow Cytometry | Bcl-2-Like Protein 11 | Forkhead Transcription Factors - metabolism | Inflammatory Bowel Diseases - genetics | Apoptosis Regulatory Proteins - genetics | Female | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Thymus Gland - metabolism | Proto-Oncogene Proteins - metabolism | Cell Survival - drug effects | Green Fluorescent Proteins - metabolism | Membrane Proteins - genetics | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Thymus Gland - cytology | Etoposide - pharmacology | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Signal Transduction - genetics | Forkhead Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Mice | Proto-Oncogene Proteins c-bcl-2 - genetics | Antigens | Medical colleges | Genes | Fluorescence | Biochemistry | Biological response modifiers | Transforming growth factors | T cells | Analysis | Medical genetics | Physiological aspects | Lymphomas | Interferon gamma | Bcl-2L1, 1Bcl-2 interacting mediator of cell death | nTreg, natural regulatory T cells | GFP, green fluorescent protein | TGF-β, transforming growth factor beta | GITR, glucocorticoid-induced TNFR-related protein | CTLA-4, cytotoxic T lymphocyte antigen 4 | BH, Bcl-2 homology | Tcon, conventional CD4+ T cells | Bcl-2, B cell lymphoma 2 | IFN-γ, interferon gamma | iTreg, induced regulatory T cells | Foxp3, Forkhead box P3 | IL, interleukin | MFI, mean fluorescence intensity | TCR, T cell receptor
Journal Article
Metabolism, ISSN 0026-0495, 12/2017, Volume 77, pp. 39 - 46
Metabolic reprogramming is shaped to support specific cell functions since cellular metabolism controls the final outcome of immune response. Multiple... 
Adipocytokines | IFN beta-1a | Multiple sclerosis | Metabolism | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | ACTIVATION | RECEPTOR | OSTEOPROTEGERIN | INTERFERON-BETA | CEREBROSPINAL-FLUID | INFLAMMATION | ENDOCRINOLOGY & METABOLISM | GLATIRAMER ACETATE | LIGAND | Interferon beta-1a - therapeutic use | Multiple Sclerosis, Relapsing-Remitting - immunology | Lymphocyte Activation | Humans | Middle Aged | Oxidative Phosphorylation | Glucose Transporter Type 1 - metabolism | Male | Mitochondria - metabolism | Glycolysis - drug effects | Case-Control Studies | Young Adult | T-Lymphocytes - metabolism | Glucose Transporter Type 1 - drug effects | Adult | Female | T-Lymphocytes - pathology | Multiple Sclerosis, Relapsing-Remitting - metabolism | Glucose metabolism | Enzymes | Relapse | Physiological aspects | Interferon | Biological response modifiers | T cells | Diseases | OCR, oxygen consumption rate | Th, T helper | E2, exone2 | MPO, myeloperoxidase | CIA, collagen-induced arthritis | DLAT, dihydrolipoamide S-acetyltransferase | BMI, body mass index | sICAM-1, soluble ICAM-1 | Tconv, conventional T cells | MCP-1, monocyte chemoattractant protein-1 | PBMCs, peripheral blood mononuclear cells | IFN, interferon | Treg, regulatory T cells | OPG, osteoprotegerin | RANKL, receptor activator of nuclear factor kappaB ligand | T1D, type 1 diabetes | sCD40L, soluble CD40 ligand | RR, relapsing remitting | sTNF-R, soluble tumor necrosis factor receptor | MS, multiple sclerosis | CNS, central nervous system | iTreg, inducible regulatory T cells | ECAR, extracellular acidification rate | sLeptinR, soluble leptin receptor | DLST, dihydrolipoamide succinyltransferase | TCR, T cell receptor | EAE, experimental autoimmune encephalomyelitis
Journal Article
BMC Biology, ISSN 1741-7007, 05/2018, Volume 16, Issue 1, pp. 47 - 35
Journal Article