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Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 05/2000, Volume 97, Issue 10, pp. 5568 - 5573
Large conductance voltage and Ca super(2+)-activated K super(+) (MaxiK) channels couple intracellular Ca super(2+) with cellular excitability. They are... 
iberiotoxin
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 11/2003, Volume 93, Issue 10, pp. 965 - 971
ABSTRACT—The molecular mechanisms underlying increased arterial tone during hypertension are unclear. In vascular smooth muscle, localized Ca release events... 
Ryanodine receptors | sparks | Sarcoplasmic reticulum | Iberiotoxin
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 08/2015, Volume 765, pp. 42 - 50
We evaluated the effects of K + channel blockers in the vascular reactivity of in vitro perfused kidneys, as well as on the influence of vasoactive agents in... 
Kidneys | Septic shock | Tetraethylammonium | Glibenclamide | Iberiotoxin
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 09/2015, Volume 309, Issue 5, pp. H835 - H843
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 04/2006, Volume 290, Issue 4, pp. H1520 - H1527
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 11/2008, Volume 295, Issue 5, pp. 1344 - 1353
We investigated the role of large-conductance Ca2+-activated K+ (BK) channels in β3-adrenoceptor (β3-AR)-induced relaxation in rat urinary bladder smooth... 
Detrusor | H89 | BRL 37344 | SR59230a | Patch-clamp | Spontaneous, transient, outward large-conductance current | Iberiotoxin | patch-clamp | Receptors and Signal Transduction | iberiotoxin | detrusor | spontaneous, transient, outward large-conductance current
Journal Article
Pflugers Archiv European Journal of Physiology, ISSN 0031-6768, 05/2010, Volume 459, Issue 6, pp. 863 - 879
Journal Article
Pharmacological Research, ISSN 1043-6618, 09/2014, Volume 87, pp. 80 - 86
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 03/2017, Volume 429, Issue 6, pp. 911 - 921
Ca concentration jumps for the activation of Ca -dependent ion channels or transporters can be obtained either by fast solution exchange or by the use of caged... 
BK channel | channelrhodopsin | calcium jump | minimal invasive | optogenetics | ACTIVATION | TRANSMEMBRANE HELICES | DETERMINANTS | IBERIOTOXIN | CALCIUM EXCHANGE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CA2+-ACTIVATED K+ CHANNELS | BETA-SUBUNITS | CHANNELRHODOPSIN-2 | ASTROCYTES | SODIUM-CALCIUM
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 09/2005, Volume 289, Issue 3, pp. 1277 - 1283
Smooth muscle membrane potential (Em) depends on K+ channels, and arteries from rats made hypertensive with Nω-nitro-l-arginine (LHR) are depolarized compared... 
4-aminopyridine | Membrane potential | Nitric oxide | Iberiotoxin
Journal Article
JOURNAL OF HYPERTENSION, ISSN 0263-6352, 06/2014, Volume 32, Issue 6, pp. 1264 - 1274
Aims:It has been demonstrated previously that inflammation in perivascular adipose tissue (PVAT) may be implicated in vascular dysfunction. The aim of this... 
hypoxia | METABOLIC SYNDROME | BKCA CHANNELS | SPONTANEOUSLY HYPERTENSIVE-RATS | obese mice | iberiotoxin | microcirculation | small arteries | RENIN-ANGIOTENSIN SYSTEM | INFLAMMATION | SUBCUTANEOUS SMALL ARTERIES | OB/OB MICE | RESISTANCE VESSELS | PERIPHERAL VASCULAR DISEASE | melatonin | obesity | ADIPOSE-TISSUE
Journal Article
Journal Article
Journal of Membrane Biology, ISSN 0022-2631, 4/2003, Volume 192, Issue 2, pp. 141 - 148
AbstractLarge-conductance Ca2+-activated K+ (BKCa) channels are sensitive to both voltage and internal [Ca2+] and are found in many tissues. Their... 
Bicistronic expression Calcium activated potassium channels hSlo Activation Inactivation Iberiotoxin Beta-subunits | Calcium activated potassium channels | Beta-subunits | Activation | Bicistronic expression | Inactivation | hSlo | Iberiotoxin
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, ISSN 0363-6143, 11/2008, Volume 295, Issue 5, pp. C1344 - C1353
Hristov KL, Cui X, Brown SM, Liu L, Kellett WF, Petkov GV. Stimulation of beta 3-adrenoceptors relaxes rat urinary bladder smooth muscle via activation of the... 
DETRUSOR MUSCLE | BKCA CHANNELS | PHYSIOLOGY | POTASSIUM CHANNELS | patch-clamp | outward large-conductance current | H89 | BRL 37344 | iberiotoxin | RELAXATION | GUINEA-PIG BLADDER | spontaneous | BETA-ADRENOCEPTORS | CELL BIOLOGY | OVERACTIVE BLADDER | transient | RYANODINE RECEPTORS | SR59230a | detrusor | ERECTILE DYSFUNCTION | MOLECULAR-MECHANISMS
Journal Article
EUROPEAN JOURNAL OF PHARMACOLOGY, ISSN 0014-2999, 10/2015, Volume 765, pp. 42 - 50
We evaluated the effects of K+ channel blockers in the vascular reactivity of in vitro perfused kidneys, as well as on the influence of vasoactive agents in... 
ABNORMAL ACTIVATION | Kidneys | POTASSIUM CHANNELS | Septic shock | Tetraethylammonium | SEPSIS | AFFERENT ARTERIOLAR TONE | INDUCED HYPORESPONSIVENESS | SHOCK | ENDOTOXEMIC RATS | PHARMACOLOGY & PHARMACY | VASCULAR REACTIVITY | DIFFERENTIAL INVOLVEMENT | Glibenclamide | GLOBAL OXYGEN-TRANSPORT | Iberiotoxin
Journal Article
Journal Article
Biochemistry (Washington), ISSN 0006-2960, 09/2001, Volume 40, Issue 37, pp. 10987 - 10997
Noxiustoxin (NxTX) displays an extraordinary ability to discriminate between large conductance, calcium-activated potassium (maxi-K) channels and voltage-gated... 
iberiotoxin | noxiustoxin
Journal Article
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