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ChemCatChem, ISSN 1867-3880, 06/2016, Volume 8, Issue 12, pp. 2171 - 2171
The cover shows the idea of the imine reductase‐catalyzed reductive amination of ketones: the direct preparation of chiral amines by merging ketones and... 
amines | imine reductase | asymmetric synthesis | reductive amination | biocatalysis
Journal Article
Journal Article
Journal of Inorganic Biochemistry, ISSN 0162-0134, 12/2015, Volume 153, pp. 346 - 354
Three new compounds containing the bis(triphenylphosphane)iminium cation (PPN+) with ClO4−, BF4− and [AgCl2]− as counter anions have been synthesized and... 
Isomorphism | Mitochondria | Anti-cancer compounds | Thioredoxin reductase | DNA binding | Crystal structure | boric acid | binding affinity | unclassified drug | imine | drug synthesis | in vitro study | hydrogen | tetrafluoridoborate | antiproliferative activity | mitochondrial respiration | enzyme inhibition | oxygen consumption | IC50 | flow cytometry | female | cancer cell line | human | mitochondrion swelling | perchlorate | antineoplastic agent | mitochondrial membrane potential | human cell | X ray diffraction | article | cell viability | controlled study | absorption spectroscopy | antineoplastic activity | membrane potential | bis(chlorido)argentate | chemical structure | drug DNA interaction | ethidium bromide | hydrogen bond | DNA-BINDING | ALPHA INHIBITOR | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | CHEMISTRY, INORGANIC & NUCLEAR | MITOCHONDRIAL THIOREDOXIN REDUCTASE | DELOCALIZED LIPOPHILIC CATIONS | PURIFICATION | SPECTRA | Amino Acid Sequence | Antineoplastic Agents - chemical synthesis | Humans | Enzyme Inhibitors - pharmacology | Molecular Sequence Data | Rats | Mitochondria - drug effects | Antineoplastic Agents - chemistry | Enzyme Inhibitors - chemical synthesis | Silver Compounds - chemistry | DNA - chemistry | Animals | Thioredoxin-Disulfide Reductase - metabolism | Organometallic Compounds - chemical synthesis | Enzyme Inhibitors - chemistry | Cell Line, Tumor | Protein Binding | Organometallic Compounds - chemistry | Antineoplastic Agents - pharmacology | Thioredoxin-Disulfide Reductase - antagonists & inhibitors | Organometallic Compounds - pharmacology | Thioredoxin-Disulfide Reductase - chemistry
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 10/2013, Volume 63, pp. 369 - 380
Journal Article
Tetrahedron, ISSN 0040-4020, 2004, Volume 60, Issue 3, pp. 753 - 758
Journal Article
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, ISSN 2296-4185, 09/2019, Volume 7
Sarcosine, an N-methylated amino acid, shows potential as antipsychotic, and serves as building block for peptide-based drugs, and acts as detergent when... 
enzyme engineering | N-ethylglycine | imine reductase | PYRUVATE | sarcosine | MULTIDISCIPLINARY SCIENCES | LYSINE | N-alkylated amino acids | DIRECTED EVOLUTION | DEHYDROGENASE | AMINATION | PEPTIDES | Corynebacterium glutamicum | AMINO-ACIDS | GLUTAMATE | LIDOCAINE | N-methylarnino acids | metabolic engineering | ACETATE | Glycine | Fermentation | Usage | N-methylamino acids
Journal Article
ACS CATALYSIS, ISSN 2155-5435, 06/2016, Volume 6, Issue 6, pp. 3880 - 3889
The imine reductase AoIRED from Amycolatopsis orientalis (Uniprot R4SNK4) catalyzes the NADPHdependent reduction of a wide range of prochiral imines and... 
NADPH | chiral amine | OPTICALLY-ACTIVE AMINES | imine reductase | CHEMISTRY, PHYSICAL | (S)-IMINE REDUCTASE | SELECTIVE REDUCTION | biocatalysis | DEHYDROGENASE | CHIRAL AMINES | PAENIBACILLUS-LACTIS | ASYMMETRIC REDUCTION | oxidoreductase | (R)-IMINE REDUCTASE | CYCLIC IMINES
Journal Article
Journal Article
ACS Catalysis, ISSN 2155-5435, 04/2017, Volume 7, Issue 4, pp. 2920 - 2925
The increasing diversity of reactions mediated by biocatalysts has led to development of multistep in vitro enzyme cascades, taking advantage of generally... 
whole cell biotransformation | enzyme cascades | gene duplication | biocatalysis | chiral piperidines | ASYMMETRIC-SYNTHESIS | HYDROGENATION | FUNCTIONALIZATIONS | CONVERSION | CHEMISTRY, PHYSICAL | (S)-IMINE REDUCTASE | CARBOXYLIC-ACID REDUCTASE | BIOSYNTHESIS | BIOCATALYST | EXPRESSION | OMEGA-TRANSAMINASES
Journal Article
Advanced Synthesis & Catalysis, ISSN 1615-4150, 06/2017, Volume 359, Issue 12, pp. 2011 - 2025
Journal Article