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European Journal of Pharmacology, ISSN 0014-2999, 03/2008, Volume 582, Issue 1-3, p. 88
The aim of the present study was to investigate the effect of antidepressant drugs (characterized by a different mechanism of action), administered jointly... 
Imipramine
Journal Article
Science Translational Medicine, ISSN 1946-6234, 03/2012, Volume 4, Issue 127, pp. 127ra36 - 127ra36
Journal Article
Journal Article
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 08/2015, Volume 65, p. 81
* Coronaridine congeners noncompetitively inhibit h[alpha]3[beta]4 AChRs. * The smaller the polar surface area, the higher the activity of coronaridine... 
Medical colleges | Imipramine
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2010, Volume 285, Issue 11, pp. 8363 - 8374
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2012, Volume 166, Issue 4, pp. 1333 - 1343
BACKGROUND AND PURPOSE Recent studies indicate that efflux of antidepressants by the multidrug resistance transporter P‐glycoprotein (P‐gp) at the blood–brain... 
blood–brain barrier | microdialysis | imipramine | antidepressant | P‐glycoprotein | treatment‐resistant depression | desipramine | blood-brain barrier | P-glycoprotein | treatment-resistant depression | PHARMACOKINETIC INTERACTION | GENE ABCB1 | IN-VITRO | CYCLOSPORINE-A | WILD-TYPE MICE | DRUGS | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | MULTIDRUG-RESISTANCE | CLINICAL-RESPONSE | VERAPAMIL | Antidepressive Agents, Tricyclic - metabolism | Injections, Intravenous | Cyclosporine - pharmacology | Antidepressive Agents, Tricyclic - pharmacokinetics | Half-Life | Male | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Imipramine - administration & dosage | Desipramine - metabolism | Drug Interactions | Antidepressive Agents, Tricyclic - administration & dosage | Imipramine - pharmacokinetics | Tissue Distribution - drug effects | Desipramine - blood | Rats | Imipramine - blood | Blood-Brain Barrier - drug effects | Rats, Sprague-Dawley | Verapamil - pharmacology | Blood-Brain Barrier - metabolism | Extracellular Fluid - metabolism | Animals | Antidepressive Agents, Tricyclic - blood | Microdialysis | Imipramine - metabolism | Biotransformation - drug effects | Prefrontal Cortex - metabolism | Metabolic Clearance Rate - drug effects | Blood-brain barrier | Drug therapy | Antidepressants | Research Papers
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 03/2015, Volume 750, p. 39
Imipramine is a tricyclic antidepressant inhibitor of norepinephrine and serotonin neuronal reuptake. The roles of specific [alpha].sub.1-adrenoceptor subtypes... 
Imipramine | Analysis | Noradrenaline
Journal Article
Cancer Cell, ISSN 1535-6108, 10/2015, Volume 28, Issue 4, pp. 456 - 471
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 01/2010, Volume 159, Issue 1, pp. 122 - 128
Journal Article
American Journal of Psychiatry, ISSN 0002-953X, 05/2015, Volume 172, Issue 5, pp. 426 - 429
The major classes of psychotropic drugs were introduced in an extraordinary decade of discovery between the late 1940s and late 1950s. In the present climate... 
PSYCHIATRY | Antidepressive Agents, Tricyclic - history | Imipramine - therapeutic use | Drug Discovery - history | Antidepressive Agents, Tricyclic - therapeutic use | History, 20th Century | Humans | Depressive Disorder - drug therapy | Imipramine - history | Switzerland | Imipramine | Depression, Mental | Discovery and exploration
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2001, Volume 21, Issue 13, pp. 4875 - 4882
The noradrenergic system is involved in the regulation of many physiological and psychological processes, including the modulation of mood. The alpha... 
imipramine
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 11/2013, Volume 45, Issue 11, p. 2420
This work presents the design and synthesis of a series of novel 2-benzylquinuclidine derivatives, comprising 12 methiodide and 11 hydrochloride salts, and... 
Medical colleges | Imipramine
Journal Article
Neuroreport, ISSN 0959-4965, 07/2001, Volume 12, Issue 10, pp. 2195 - 2198
This study aimed to assess the effects of the antidepressant drug imipramine (IMI) on the neuronal M-type K super(+) current (I sub(K(M))). We show that IMI... 
imipramine
Journal Article
Journal Article