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by Chen and Hu and Wang and Zhao and Yang and Li and Liu and Zhou and Bao and Wu
International Journal of Molecular Sciences, ISSN 1422-0067, 09/2019, Volume 20, Issue 19, p. 4874
Melanocytes (MCs) are specialized cells that synthesize melanin within the melanosome. Cultured MCs are useful in order to study their role in relation to... 
melanocytes | malignant transformation | immortalization | cell lines | SV40-LT
Journal Article
International Journal of Molecular Sciences, ISSN 1422-0067, 09/2019, Volume 20, Issue 18, p. 4595
Tumor angiogenesis research and antiangiogenic drug development make use of cultured endothelial cells (ECs) including the human microvascular ECs among... 
tumor endothelial cells | renal carcinoma | immortalization | angiogenesis
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 10/2019, Volume 38, Issue 19, pp. e96659 - n/a
Loss of the histone H3.3‐specific chaperone component ATRX or its partner DAXX frequently occurs in human cancers that employ alternative lengthening of... 
ATRX/DAXX | ALT | immortalization | DNA damage | telomere | Chromatin | Yeast | Immunoprecipitation | Homology | Maintenance | Cell immortalization | DNA repair | DNA biosynthesis | Telomeres | Daxx protein | Depletion | Immortalization | Cell cycle | Histones | Replication | Repair | Telomerase | Deoxyribonucleic acid--DNA | Histone H3
Journal Article
Toxicological Sciences, ISSN 1096-6080, 12/2005, Volume 88, Issue 2, pp. 285 - 286
Journal Article
Genes and Development, ISSN 0890-9369, 2000, Volume 14, Issue 23, pp. 3037 - 3050
Journal Article
Aging, ISSN 1945-4589, 05/2019, Volume 11, Issue 10, pp. 3012 - 3022
Aging is associated with a genome-wide change of DNA methylation (DNAm). "DNAm age" is defined as the predicted chronological age by the age estimator based on... 
DNA methylation | Hypoxia | Epigenetic clock | Immortalization | Epigenetic age
Journal Article
Cancer Research, ISSN 0008-5472, 09/2018, Volume 78, Issue 17, pp. 5107 - 5123
Cell-type origin is one of the factors that determine molecular features of tumors, but resources to validate this concept are scarce because of technical... 
PATHWAYS | TRANSITION | ACTIVATION | CANCER CELLS | TRANSCRIPTOME | ONCOLOGY | MAMMARY STEM-CELLS | IDENTIFICATION | EMT | IMMORTALIZATION | HIERARCHY
Journal Article
Oncogene, ISSN 0950-9232, 11/2012, Volume 31, Issue 46, pp. 4815 - 4827
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 02/2018, Volume 10, Issue 2, pp. 254 - 275
Journal Article
Transfusion Clinique et Biologique, ISSN 1246-7820, 09/2017, Volume 24, Issue 3, pp. 263 - 267
Population ageing and increase in cancer incidence may lead to a decreased availability of red blood cell units. Thus, finding an alternative source of red... 
Red blood cells | Transfusion | Immortalisation | Transgenesis
Journal Article
Biochimica et biophysica acta. Molecular and cell biology of lipids, ISSN 1388-1981, 08/2019, p. 158511
Brown adipose tissue (BAT) is a potential target to treat cardiometabolic disorders because of its capacity to combust glucose and fatty acids for... 
Journal Article
Scientific reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 500 - 10
Robust in vitro lung models are required for risk assessment to measure key events leading to respiratory diseases. Primary normal human bronchial epithelial... 
TRANSFORMATION | AIRWAY | VIRUS | MULTIDISCIPLINARY SCIENCES | LINE | GENERATION | IMMORTALIZATION | EXPRESSION
Journal Article
Oncogene, ISSN 0950-9232, 01/2002, Volume 21, Issue 4, pp. 598 - 610
Some immortalized mammalian cell lines and tumors maintain or increase the overall length of their telomeres in the absence of telomerase activity by one or... 
Recombination | Alternative lengthening of telomeres | Telomere | Immortalization | ALT-associated PML bodies | Cancer
Journal Article