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06/2018, OECD Guidelines for the Testing of Chemicals, Section 4, 21
The present Key Event based Test Guideline (TG) addresses the human health hazard endpoint skin sensitisation, following exposure to a test chemical. More... 
h-CLAT | Environment | skin sensitisation | in vitro method
eBook
Journal Article
Journal Article
Cell Biology and Toxicology, ISSN 0742-2091, 4/2009, Volume 25, Issue 2, pp. 109 - 126
Journal Article
06/2018, OECD Guidelines for the Testing of Chemicals, Section 4, 20
The present Test Guideline addresses the human health hazard endpoint skin sensitisation, following exposure to a test chemical. Skin sensitisation refers to... 
Environment | skin sensitisation | keratinosens | in vitro test method
eBook
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1800, pp. 485 - 504
Journal Article
International journal of molecular sciences, ISSN 1422-0067, 02/2019, Volume 20, Issue 3
There is an increasing demand for alternative in vitro methods to replace animal testing, and, to succeed, new methods are required to be at least as accurate... 
next generation in vitro tests | adverse outcome pathways | genomics | skin sensitization | machine learning | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Farmakologi och toxikologi | Pharmacology and Toxicology
Journal Article
Journal of Applied Toxicology, ISSN 0260-437X, 05/2016, Volume 36, Issue 5, pp. 669 - 684
Sensitization to chemicals resulting in an allergy is an important health issue. The current gold‐standard method for identification and characterization of... 
local lymph node assay | potency | antigen‐specific priming | in vitro alternative to animal testing | skin sensitization | T‐cell proliferation | interferon‐γ | Interferon-γ | Skin sensitization | Local lymph node assay | Potency | Antigen-specific priming | T-cell proliferation | INVITRO PREDICTIVE TEST | ALLERGIC CONTACT-DERMATITIS | DENDRITIC CELLS | LYMPH-NODE ASSAY | EXPLANT MODEL | interferon | VERSUS-HOST-DISEASE | antigen-specific priming | CYTOKINE PRODUCTION | HUMAN BLOOD | TOXICOLOGY | BONE-MARROW TRANSPLANTS | T-CELLS | Cell Survival - drug effects | Leukocytes, Mononuclear - metabolism | Leukocytes, Mononuclear - drug effects | Skin Tests | Risk Assessment | Animal Testing Alternatives | Humans | Cells, Cultured | Interferon-gamma - metabolism | Irritants - toxicity | Local Lymph Node Assay | Dose-Response Relationship, Drug | Animals | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Sensitivity and Specificity | Leukocytes, Mononuclear - cytology | Cell Proliferation - drug effects | Mice | Haptens - toxicity | In Vitro Techniques | Allergens - toxicity | Skin - drug effects | Medical tests | Skin | Interferon | Biological response modifiers | T cells | Analysis | Index Medicus | Sensitizing | Human | Health | Correlation coefficients | Human behavior | Damage | Hazard assessment | Lymph
Journal Article