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Journal Article
Proceedings of SPIE, ISSN 0277-786X, 04/2008, Volume 6991, Issue 1, pp. 69912C - 69912C-7
A molecular imaging method employing acetic acid dilute solution as a biomarker of cervical neoplasia is described and the interpretation of the biophysical... 
Neoplasia screening | Biological system modeling | Scattering | Cervical cancer | Biomedical imaging
Conference Proceeding
Proceedings of SPIE, ISSN 0277-786X, 02/2007, Volume 6430, Issue 1, pp. 64300Q - 64300Q-11
We report the development of a probability-based multi-class diagnostic algorithm to simultaneously distinguish highgrade dysplasia from low-grade dysplasia,... 
Maximum Representation and Discrimination Feature (MRDF) | Multi-class diagnostic algorithm | Cervical dysplasia | Posterior probability | Raman spectroscopy | Sparse Multinomial Logistic Regression (SMLR)
Conference Proceeding
Proceedings of SPIE, ISSN 0277-786X, 02/2008, Volume 6853, Issue 1, pp. 685317 - 685315
The purpose of this study is to explore the feasibility of utilizing near-infrared (NIR) autofluorescence spectroscopy for diagnosis of precancer (i.e.,... 
Linear discriminant analysis | Precancer | Cervix | Near infrared autofluorescence | In vivo diagnosis | Principal component analysis
Conference Proceeding
Gynecologic Oncology, ISSN 0090-8258, 2007, Volume 107, Issue 1, pp. S138 - S146
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 2007, Volume 107, Issue 1, pp. S248 - S255
Abstract Objective This review evaluates the diagnostic efficacy of fluorescence spectroscopy, reflectance spectroscopy, and their combination that use both... 
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | Fluorescence spectroscopy | Reflectance spectroscopy | Combined fluorescence and reflectance spectroscopy | In vivo cervical diagnosis | Optical spectroscopy | Point probe spectroscopy | Cervical intraepithelial neoplasia (CIN) | Real-time diagnosis | High-grade SIL (HG-SIL) | Multispectral spectroscopy or imaging, sensitivity, and specificity of cervical diagnosis | Sqaumous intraepithelial lesion (SIL) | OPTICAL-DETECTION | SQUAMOUS INTRAEPITHELIAL LESIONS | COLLAGEN | CANCER | OBSTETRICS & GYNECOLOGY | point probe spectroscopy | UTERINE CERVIX | sqaumous intraepithelial lesion (SIL) | cervical intraepithelial neoplasia (CIN) | and specificity of cervical diagnosis | PRECANCER | reflectance spectroscopy | high-grade SIL (HG-SIL) | CIN | real-time diagnosis | fluorescence spectroscopy | EXCITATION WAVELENGTHS | in vivo cervical diagnosis | ONCOLOGY | multispectral spectroscopy or imaging | optical spectroscopy | sensitivity | combined fluorescence and reflectance spectroscopy | SPECTRA | PROGRAM | Spectrometry, Fluorescence - methods | Spectrometry, Fluorescence - instrumentation | Uterine Cervical Neoplasms - diagnosis | Humans | Cervical Intraepithelial Neoplasia - diagnosis | Image Processing, Computer-Assisted - instrumentation | Female | Optics and Photonics - instrumentation | Image Processing, Computer-Assisted - methods | Fluorescence | Spectrum analysis | Index Medicus
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 2007, Volume 107, Issue 1, pp. S270 - S280
Abstract Objective In this review, we focus on the pilot, Phase I, II, and III clinical trials of fluorescence spectroscopy, reflectance spectroscopy, and... 
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | Fluorescence spectroscopy | Reflectance spectroscopy | Combined fluorescence and reflectance spectroscopy | In vivo cervical diagnosis | Squamous intraepithelial lesion (SIL) | High-grade SIL (HGSIL) | Multi-spectral device | Point probe device | Sensitivity and specificity of cervical diagnosis | Optical spectroscopy | Multi-spectral imaging | Cervical intraepithelial neoplasia (CIN) | Real-time diagnosis | SYSTEM | OPTICAL-DETECTION | SQUAMOUS INTRAEPITHELIAL LESIONS | high-grade SIL (HGSIL) | CANCER | point probe device | OBSTETRICS & GYNECOLOGY | UTERINE CERVIX | cervical intraepithelial neoplasia (CIN) | sensitivity and specificity of cervical diagnosis | PRECANCER | reflectance spectroscopy | CIN | real-time diagnosis | fluorescence spectroscopy | multi-spectral device | multi-spectral imaging | EXCITATION WAVELENGTHS | in vivo cervical diagnosis | ONCOLOGY | squamous intraepithelial lesion (SIL) | optical spectroscopy | combined fluorescence and reflectance spectroscopy | SPECTRA | PROGRAM | Spectrometry, Fluorescence - methods | Uterine Cervical Neoplasms - diagnosis | Humans | Middle Aged | Adolescent | Aged, 80 and over | Cervical Intraepithelial Neoplasia - diagnosis | Adult | Female | Aged | Clinical Trials as Topic - methods | Optics and Photonics | Fluorescence | Clinical trials | Spectrum analysis | Index Medicus
Journal Article
01/2011, ISBN 9780494795965
An in-vivo technique providing real-time automated diagnosis would be an ideal alternative to Pap smears in many parts of the world. Mid-infrared spectrometry... 
Optics | Oncology | Biomedical engineering
Dissertation
JOURNAL OF CELLULAR BIOCHEMISTRY, ISSN 0730-2312, 1994, pp. 111 - 119
A quantitative measure of intraepithelial neoplasia which can be made in vivo without the need for tissue removal would be of clinical significance. Our group... 
OPTICAL FIBER | BIOCHEMISTRY & MOLECULAR BIOLOGY | TISSUE | NORMAL TISSUE | LASER-INDUCED FLUORESCENCE | DYSPLASIA | CIN | CARCINOMA | AUTOFLUORESCENCE | CELL BIOLOGY
Journal Article
01/2011, ISBN 9780494795965, Volume 50, Issue 1
An in-vivo technique providing real-time automated diagnosis would be an ideal alternative to Pap smears in many parts of the world. Mid-infrared spectrometry... 
Spectroscopy | Spectrometry | Evanescent waves | Silver halides | Spectra | Diagnosis | Fibers
Book Chapter