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by Xue, X and Shah, YM
CARCINOGENESIS, ISSN 0143-3334, 01/2013, Volume 34, Issue 1, pp. 163 - 169
Cyclooxygenase 2 (COX2) is overexpressed in 80% of colon adenocarcinomas. However, the mechanism leading to aberrant COX2 expression in tumors is unclear.... 
CYCLOOXYGENASE-2 GENE-EXPRESSION | TRANSCRIPTIONAL ACTIVITY | ONCOLOGY | PROSTAGLANDIN-E SYNTHASE-1 | INDOLEAMINE 2,3-DIOXYGENASE | INTESTINAL TUMORIGENESIS | VASCULAR ENDOTHELIAL-CELLS | COX-2 INHIBITORS | UP-REGULATION | NF-KAPPA B | HUMAN COLORECTAL-CANCER
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2009, Volume 123, Issue 1, pp. 239 - 248
Journal Article
Journal of Cancer, ISSN 1837-9664, 2019, Volume 10, Issue 1, pp. 267 - 276
Background: Indoleamine 2,3-dioxygenase (IDO), an enzyme involved in tryptophan (Trp) metabolism, is generally considered to be an immunosuppressive molecule.... 
Indoleamine 2 | Prognosis | Radical resection | Lung cancer | 3-dioxygenase | KYNURENINE | CELLS | 2,3-DIOXYGENASE EXPRESSION | ANTITUMOR-ACTIVITY | prognosis | lung cancer | INHIBITION | ONCOLOGY | ARYL-HYDROCARBON RECEPTOR | COLORECTAL-CANCER | radical resection | Indoleamine 2,3-dioxygenase | TRYPTOPHAN DEGRADATION | DISEASE PROGRESSION
Journal Article
Journal of Neuroimmunology, ISSN 0165-5728, 2016, Volume 305, pp. 167 - 171
Journal Article
Journal Article
PLOS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1
gamma delta T cells play a role in a wide range of diseases such as autoimmunity and cancer. The majority of circulating human gamma delta T lymphocytes... 
ENCEPHALOMYELITIS | RESPONSES | CYTOKINE ANALYSIS | INHIBITION | INTERFERON-GAMMA | MULTIDISCIPLINARY SCIENCES | INDOLEAMINE 2,3-DIOXYGENASE | DELTA T-CELLS | STROMAL CELLS | CYTOTOXICITY | LYMPHOCYTE-PROLIFERATION
Journal Article
BioImpacts, ISSN 2228-5652, 2019, Volume 9, Issue 1, pp. 1 - 3
Trafficking of macromolecular immunotherapy agent into the tumor microenvironment (TME) is a challenging issue. In the TME, cancer cells exploit indoleamine 2,... 
Indoleamine 2 | IDO inhibitor | Cancer therapy | Immunotherapy | Kynurenine | Solid tumors | 3-dioxygenase | Indoleamine 2, 3-dioxygenase
Journal Article
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, ISSN 1449-1907, 2019, Volume 16, Issue 8, pp. 1107 - 1115
Astragalus membranaceus has been shown to possess anti-inflammation and antitumor properties. Several studies have indicated that extracts of Astragalus... 
RESVERATROL | PROTEIN | PROTECTION | JUNCTIONAL INTERCELLULAR COMMUNICATION | SALMONELLA | CHEMOPREVENTION | Connexin 43 | Combination therapy | MEDICINE, GENERAL & INTERNAL | CONNEXIN-43 | INHIBITION | Indoleamine 2, 3-dioxygenase | PG2 | Astragalus membranaceus
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 08/2017, Volume 139, Issue 34, pp. 11887 - 11894
3-Substituted 2-oxindoles are important structural motifs found in many biologically active natural products and pharmaceutical lead compounds. Here, we report... 
ENANTIOSELECTIVE SYNTHESIS | MECHANISM | 2ND ENZYME | CRYSTAL-STRUCTURE | INDOLEAMINE 2,3-DIOXYGENASE | PYRROLNITRIN BIOSYNTHETIC-PATHWAY | TUMORAL IMMUNE RESISTANCE | CHEMISTRY, MULTIDISCIPLINARY | SUBSTRATE RECOGNITION | SPIROOXINDOLES | INSIGHTS
Journal Article
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 05/2019, Volume 10, p. 452
Depression is an incapacitating neuropsychiatric disorder. The serotonergic system in the brain plays an important role in the pathophysiology of depression.... 
LIPID-PEROXIDATION | KYNURENINE PATHWAY | INDOLEAMINE 2,3-DIOXYGENASE | quinolinic acid | MAJOR DEPRESSION | TERT-BUTYLHYDROQUINONE | serotonin | TRANSCRIPTION FACTOR NRF2 | Nrf2 | MOUSE MODEL | PHARMACOLOGY & PHARMACY | depression | STRIATAL NEURONS | oxidative stress | tryptophan | BRAIN | Depression, Mental
Journal Article
Oncogene, ISSN 0950-9232, 05/2008, Volume 27, Issue 20, pp. 2851 - 2857
Journal Article