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Molecular Cancer Research, ISSN 1541-7786, 07/2013, Volume 11, Issue 7, pp. 793 - 807
Evidence suggests that bioactive lipids may regulate pathophysiologic functions such as cancer cell metastasis. Therefore, we determined that the bioactive... 
PROGENITOR CELLS | COMPLEMENT CASCADE | ONCOLOGY | CELL-MIGRATION | BONE-MARROW | METASTATIC BEHAVIOR | INHIBITORY FACTOR | UP-REGULATION | 1-PHOSPHATE STIMULATES PROLIFERATION | RECEPTOR EXPRESSION PROFILE | SPHINGOSINE 1-PHOSPHATE | CELL BIOLOGY | Lysophospholipids - metabolism | Cell Adhesion - radiation effects | Humans | Actins - metabolism | Rhabdomyosarcoma - pathology | Antineoplastic Agents - therapeutic use | Bone Marrow - radiation effects | Down-Regulation - radiation effects | Cellular Microenvironment - radiation effects | Neoplasm Metastasis | Rhabdomyosarcoma - radiotherapy | Rhabdomyosarcoma - drug therapy | Antineoplastic Agents - pharmacology | Sphingosine - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Receptors, Lysosphingolipid - metabolism | Bone Marrow - drug effects | Aptamers, Nucleotide - pharmacology | Cell Survival - drug effects | Ceramides - metabolism | Mice, Inbred C57BL | Cell Adhesion - drug effects | Down-Regulation - drug effects | Enzyme Activation - drug effects | Cell Survival - radiation effects | Enzyme Activation - radiation effects | Cell Movement - radiation effects | Cell Movement - drug effects | Rhabdomyosarcoma - enzymology | Sphingosine - analogs & derivatives | Animals | Cell Line, Tumor | Cytoskeleton - metabolism | Cell Proliferation - drug effects | Mice | Cellular Microenvironment - drug effects | Cytoskeleton - drug effects | Cell Proliferation - radiation effects | Mitogen-Activated Protein Kinases - metabolism
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 07/2008, Volume 28, Issue 27, pp. 6974 - 6982
Feedforward inhibition of neurons is a fundamental component of information flow control in the brain. We studied the roles played by neurogliaform cells... 
AREA CA1 | SYNAPTIC VESICLE | NEUROSCIENCES | CA1 PYRAMIDAL NEURONS | CORTEX COMBINED SLICE | TRANSMITTER RELEASE | ENTORHINAL CORTEX | GABA(B) receptor | feedforward inhibition | SYNAPSES | temporoammonic path | Ca2+ imaging | interneuron | synaptic transmission | RAT HIPPOCAMPUS | INTERNEURONS | STRATUM-LACUNOSUM-MOLECULARE | Pyramidal Cells - metabolism | Neural Pathways - drug effects | Synaptic Transmission - physiology | Calcium - metabolism | gamma-Aminobutyric Acid - metabolism | Calcium Signaling - physiology | Neuroglia - drug effects | Neural Inhibition - physiology | Receptors, GABA-A - drug effects | Synaptic Transmission - drug effects | Interneurons - cytology | Pyramidal Cells - drug effects | Action Potentials - drug effects | Organ Culture Techniques | Baclofen - pharmacology | Receptors, GABA-B - drug effects | Calcium - pharmacology | Interneurons - drug effects | Neuroglia - physiology | Inhibitory Postsynaptic Potentials - physiology | Rats | Hippocampus - cytology | GABA Antagonists - pharmacology | Action Potentials - physiology | Hippocampus - metabolism | Animals | Interneurons - metabolism | Calcium Signaling - drug effects | Phosphinic Acids - pharmacology | GABA Agonists - pharmacology | Neural Pathways - cytology | Neural Pathways - metabolism | Receptors, GABA-A - metabolism | Propanolamines - pharmacology | Neural Inhibition - drug effects | Inhibitory Postsynaptic Potentials - drug effects | Receptors, GABA-B - metabolism | Index Medicus
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 09/2015, Volume 83, pp. 151 - 163
Journal Article
Nature, ISSN 0028-0836, 08/2012, Volume 488, Issue 7413, pp. 621 - 626
Journal Article
Food Hydrocolloids, ISSN 0268-005X, 11/2019, Volume 96, pp. 568 - 576
In this study, the influence of ultrasound irradiation on the characterization and α-glucosidase inhibitory effect of polysaccharide from blackberry fruit... 
Blackberry polysaccharide | Inhibitory mechanism | Ultrasonication | α-Glucosidase | MOLECULAR-WEIGHT | ACID | MECHANISM | HYPOGLYCEMIC ACTIVITIES | FOOD SCIENCE & TECHNOLOGY | PHENOLICS | MULBERRY FRUIT | EXTRACTION | FRACTIONS | ANTIOXIDANT | alpha-Glucosidase | DEGRADATION | CHEMISTRY, APPLIED
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2010, Volume 143, Issue 1, pp. 136 - 142
The use of glioblastoma-targeted drug delivery system facilitates efficient delivery of chemotherapeutic agents to malignant gliomas in the central nervous... 
c(RGDyK) | PEG-PLA micelle | Glioblastoma | Paclitaxel | C(RGDyK) | APOPTOSIS | TARGETED DRUG-DELIVERY | ANGIOGENESIS | BRAIN-TUMOR GROWTH | POLYMERIC MICELLES | ANTITUMOR-ACTIVITY | CHEMISTRY, MULTIDISCIPLINARY | PEPTIDE | IN-VIVO | PHARMACOLOGY & PHARMACY | ALPHA(V)BETA-INTEGRIN EXPRESSION | LIPOSOMES | Injections, Intravenous | Humans | Brain Neoplasms - pathology | Biological Availability | Polyethylene Glycols - chemistry | Paclitaxel - pharmacokinetics | Brain Neoplasms - metabolism | Integrin alphaVbeta3 - metabolism | Peptides, Cyclic - chemistry | Peptides, Cyclic - metabolism | Drug Carriers | Dose-Response Relationship, Drug | Paclitaxel - chemistry | Antineoplastic Agents, Phytogenic - administration & dosage | Micelles | Drug Compounding | Inhibitory Concentration 50 | Glioblastoma - metabolism | Paclitaxel - administration & dosage | Antineoplastic Agents, Phytogenic - pharmacokinetics | Lactates - chemistry | Cell Survival - drug effects | Antineoplastic Agents, Phytogenic - chemistry | Technology, Pharmaceutical - methods | Brain Neoplasms - drug therapy | Chemistry, Pharmaceutical | Particle Size | Xenograft Model Antitumor Assays | Animals | Tumor Burden - drug effects | Mice, Nude | Glioblastoma - pathology | Cell Line, Tumor | Mice | Glioblastoma - drug therapy | Drugs | Ethylene glycol | Polyethylene | Cell research | Drug delivery systems | Peptides | Gliomas | Analysis | Lactic acid | Integrins | Vehicles | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2013, Volume 33, Issue 9, pp. 3953 - 3966
Down syndrome (DS) is associated with neurological complications, including cognitive deficits that lead to impairment in intellectual functioning. Increased... 
Protein Binding - genetics | Electric Stimulation | Cell Count | Male | GABA Modulators - therapeutic use | Learning Disorders - etiology | Hyperkinesis - drug therapy | Neurogenesis - genetics | Long-Term Potentiation - drug effects | Protein Binding - drug effects | Exploratory Behavior - drug effects | Reflex, Startle - drug effects | Imidazoles - therapeutic use | Excitatory Postsynaptic Potentials - genetics | Disease Models, Animal | Mice, Transgenic | Hippocampus - pathology | Imidazoles - pharmacology | Psychomotor Performance - drug effects | Hyperkinesis - etiology | Vesicular Inhibitory Amino Acid Transport Proteins - metabolism | Analysis of Variance | Seizures - etiology | Glutamate Decarboxylase - metabolism | Mice | Receptors, GABA-A - metabolism | Benzodiazepines - therapeutic use | Tritium - pharmacokinetics | Sensory Gating - drug effects | Reflex - genetics | Reflex - drug effects | Hippocampus - drug effects | Excitatory Postsynaptic Potentials - drug effects | Ki-67 Antigen | Reaction Time - drug effects | GABA Modulators - pharmacology | Neurons - physiology | Down Syndrome - complications | Membrane Proteins - metabolism | Neurogenesis - drug effects | Neurons - drug effects | Cues | Down Syndrome - pathology | Benzodiazepines - pharmacology | Acoustic Stimulation | Mice, Inbred C57BL | Learning Disorders - drug therapy | Long-Term Potentiation - genetics | Biophysics | Maze Learning - drug effects | Rotarod Performance Test | Animals | Carrier Proteins - metabolism | Down Syndrome - drug therapy | Cell Proliferation - drug effects
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 01/2015, Volume 17, Issue 1, pp. 74 - 81
Aims To examine whether 12 weeks of treatment with a dipeptidyl peptidase‐4 (DPP‐4) inhibitor, sitagliptin, influences the insulin secretion induced by... 
metformin | randomised trial | DPP‐IV inhibitor | insulin secretion | GLP‐1 | GIP | GLP-1 | Metformin | Randomised trial | DPP-IV inhibitor | Insulin secretion | HEALTHY-SUBJECTS | BLOOD-GLUCOSE | 1ST-DEGREE RELATIVES | RECEPTOR EXPRESSION | DOWN-REGULATION | INCRETIN HORMONES | GLUCAGON-LIKE PEPTIDE-1 | NEAR-NORMALIZATION | ENDOCRINOLOGY & METABOLISM | ORAL GLUCOSE | TYPE-2 DIABETES-MELLITUS | Glycated Hemoglobin A - analysis | Triazoles - adverse effects | Gastric Inhibitory Polypeptide - metabolism | Metformin - therapeutic use | C-Peptide - blood | Dipeptidyl-Peptidase IV Inhibitors - adverse effects | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Middle Aged | Male | Pyrazines - therapeutic use | Diabetes Mellitus, Type 2 - metabolism | Insulin - blood | Drug Therapy, Combination - adverse effects | Insulin-Secreting Cells - metabolism | Female | Sitagliptin Phosphate | Insulin Secretion | Triazoles - therapeutic use | Hypoglycemic Agents - therapeutic use | Hyperglycemia - prevention & control | Double-Blind Method | Glucagon-Like Peptide 1 - metabolism | Up-Regulation - drug effects | Diabetes Mellitus, Type 2 - blood | Insulin - metabolism | Insulin-Secreting Cells - drug effects | Pyrazines - adverse effects | Glucose Clamp Technique | Diabetes Mellitus, Type 2 - drug therapy | Type 2 diabetes | Glucose metabolism | Glucose | Glucagon | Dextrose
Journal Article
Journal Article