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PLoS ONE, ISSN 1932-6203, 04/2009, Volume 4, Issue 4, pp. e5254 - e5254
textabstractBackground: This Phase 1/2a study evaluated the safety, immunogenicity, and efficacy of an experimental malaria vaccine comprised of the... 
parasite antibody | pruritus | myalgia | papule | drug combination | major clinical study | drug dose comparison | apical membrane antigen I | malaria falciparum | Plasmodium | Plasmodium falciparum | fatigue | double blind procedure | phase 1 clinical trial | drug fever | female | protozoal protein | immunology | clinical trial | apical membrane antigen 1 | lipid A | drug safety | malaria vaccine | article | immunogenicity | nausea | antibody response | adolescent | animal | injection site erythema | metabolism | adult | male | drug derivative | injection site swelling | gamma interferon | injection site pain | arthralgia | antibody detection | enzyme linked immunosorbent assay | immunological adjuvant | chloroquine | drug eruption | genetics | controlled clinical trial | ASO2A adjuvant | sporozoite | human | skin inflammation | parasite antigen | phase 2 clinical trial | drug megadose | parasitemia | low drug dose | middle aged | liposome | randomized controlled trial | controlled study | allele | saponin | drug efficacy | membrane protein | drug induced headache | malaise | NATURAL IMMUNE-RESPONSES | FALCIPARUM CIRCUMSPOROZOITE PROTEIN | IMMUNIZATION | SAFETY | FORMULATIONS | PLASMODIUM-FALCIPARUM | MULTIDISCIPLINARY SCIENCES | MONKEYS | NAIVE ADULTS | PRECLINICAL EVALUATION | IMMUNOGENICITY TRIAL | Malaria, Falciparum - prevention & control | Adjuvants, Immunologic - administration & dosage | Adjuvants, Immunologic - pharmacology | Antigens, Protozoan - immunology | Saponins - administration & dosage | Humans | Lipid A - analogs & derivatives | Middle Aged | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Malaria Vaccines - adverse effects | Antigens, Protozoan - administration & dosage | Malaria Vaccines - immunology | Adult | Plasmodium falciparum - metabolism | Antigens, Protozoan - genetics | Protozoan Proteins - administration & dosage | Lipid A - administration & dosage | Double-Blind Method | Enzyme-Linked Immunosorbent Assay | Membrane Proteins - genetics | Membrane Proteins - immunology | Membrane Proteins - administration & dosage | Animals | Malaria Vaccines - administration & dosage | Adolescent | Alleles | Lipid A - pharmacology | Drug Combinations | Protozoan Proteins - immunology | Saponins - pharmacology | Antigens | Medical research | Malaria | Analysis | Medical societies | Vaccination | Malaria vaccine | Medicine, Experimental | Interferon | Vaccines | Biological response modifiers | Health care | Growth rate | Peptides | Goats | Homology | Parasites | Appropriate technology | Aquatic insects | Proteins | Confidence intervals | Biological effects | Pain | Lymphocytes | Mathematical models | Safety | Parasitemia | Recombinant | Formulations | Vector-borne diseases | Enzymes | Evaluation | Immune response | Effectiveness | Statistical analysis | Membrane proteins | Studies | Polymerase chain reaction | Mosquitoes | Population (statistical) | Immunogenicity | γ-Interferon | Light microscopy | Adults | Erythema
Journal Article
Vaccine, ISSN 0264-410X, 04/2019, Volume 37, Issue 18, pp. 2482 - 2493
The ZOE-50 (NCT01165177) and ZOE-70 (NCT01165229) phase 3 clinical trials showed that the adjuvanted recombinant zoster vaccine (RZV) was ≥90% efficacious in... 
Vaccine | Varicella-zoster virus | Safety | Reactogenicity | MEDICINE, RESEARCH & EXPERIMENTAL | POPULATION | EFFICACY | OLDER | ADULTS | IMMUNOLOGY | IMMUNOGENICITY | HERPES-ZOSTER | SUBUNIT CANDIDATE VACCINE | AGE | Clinical trials | Product development | Vaccines | Shingles (Disease) | Analysis | Medical research | Dictionaries | Signs and symptoms | Herpes zoster | Psoriasis | Disease | Guillain-Barre syndrome | Vaccination | Nervous system | Studies | Pulmonary fibrosis | Pain | Risk assessment | Rheumatoid arthritis | Adults | Age | Recombinant | injection site warmth | fatigue | coughing | rhinopharyngitis | alopecia areata | polyradiculoneuropathy | placebo | fibrosing alveolitis | Health Sciences | dizziness | brain infarction | herpes zoster | mixed connective tissue disease | drug safety | autoimmune pancreatitis | injection site pruritus | supraventricular tachycardia | syndrome CREST | rheumatic polymyalgia | uveitis | rheumatoid arthritis | cerebrovascular accident | age distribution | paraneoplastic neuropathy | psoriasis | erythema nodosum | injection site erythema | adult | male | vaccination | information processing | acute kidney failure | septic shock | trigeminus neuralgia | Medicin och hälsovetenskap | cohort analysis | Article | fever | trigeminal nerve disease | lichen planus | autoimmune thyroiditis | oropharynx pain | celiac disease | sex ratio | single blind procedure | Guillain Barre syndrome | multiple sclerosis | aged | varicella zoster vaccine | phase 3 clinical trial | temporal arteritis | randomized controlled trial | backache | drug efficacy | glomerulonephritis | malaise | myalgia | Medical and Health Sciences | Public Health, Global Health, Social Medicine and Epidemiology | major clinical study | chill | Hälsovetenskaper | heart infarction | cardiogenic shock | lung tumor | clinical evaluation | lung fibrosis | retina detachment | atrial fibrillation | immunoglobulin A nephropathy | pemphigus | Graves disease | Raynaud phenomenon | heart atrium flutter | ulcerative colitis | female | neuritis | facial nerve paralysis | heart failure | vitiligo | Crohn disease | multiple organ failure | psoriatic arthritis | tachycardia | sepsis | chronic gastritis | cardiopulmonary insufficiency | injection site swelling | injection site pain | arthralgia | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | radiculitis | follow up | idiopathic thrombocytopenic purpura | systemic lupus erythematosus | aortic stenosis | pneumonia | spondyloarthropathy | pancreas carcinoma | priority journal | insulin dependent diabetes mellitus | human | race | disease course | systemic juvenile idiopathic arthritis | controlled study | population research | respiratory failure | chronic obstructive lung disease | headache | upper respiratory tract infection
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 06/2008, Volume 25, Issue 6, pp. 1256 - 1273
Influenza vaccination represents the cornerstone of influenza prevention. However, today all influenza vaccines are formulated as liquids that are unstable at... 
influenza | dipalmitoylphosphatidylcholine | injection site swelling | subunit vaccine | live vaccine | Needle-free dosage forms | excipient | injection site pain | hetastarch | drug dosage form comparison | mannitol | Spray-freeze drying | virosome vaccine | inulin | review | dextran | drug fever | supercritical drying | priority journal | Influenza vaccine | human | supercritical fluid | dry powder | clinical trial | drug formulation | Stability | freeze drying | Spray drying | Stock piling for pandemics | trehalose | vacuum drying | Lyophilization | immunogenicity | desiccation | Influenza virus | xylose | Analytical challenges | inactivated virus vaccine | drug induced headache | Virosomes | methodology | drug stability | Biochemistry, general | influenza vaccine | lyophilization | stock piling for pandemics | Biomedical Engineering | virosomes | needle-free dosage forms | Biomedicine | Pharmacy | Medical Law | analytical challenges | spray-freeze drying | Pharmacology/Toxicology | spray drying | stability | SUGAR GLASSES | DELIVERY TECHNOLOGY | VIRUS-VACCINE | PANDEMIC INFLUENZA | WHOLE-VIRUS | CHEMISTRY, MULTIDISCIPLINARY | SUBUNIT VACCINE | SUPERCRITICAL-FLUID TECHNOLOGY | DRY STATE | MUCOSAL IMMUNE-RESPONSES | LIPID/DNA COMPLEXES | PHARMACOLOGY & PHARMACY | Influenza Vaccines - administration & dosage | Powders | Vaccines, Attenuated - immunology | Influenza Vaccines - immunology | Drug Stability | Humans | Freeze Drying | Influenza Vaccines - chemistry | Influenza vaccines | Development and progression | Influenza | Chemistry | Pharmacology | Vaccines | Drug dosages | Expert Review
Journal Article
Journal Article
Zairyo/Journal of the Society of Materials Science, Japan, ISSN 0514-5163, 09/2013, Volume 62, Issue 9, pp. 593 - 597
Journal Article