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1. In vitro mutagenesis protocols
by Braman, Jeff and SpringerLink (Online service)
2002, 2nd ed., Methods in molecular biology, ISBN 0896039102, Volume 182., xvi, 287
In the post-genome era, in vitro mutagenesis has emerged as the critically important tool used by molecular biologists in establishing the functions of... 
Mutagenesis | Methodology | Mutation (Biology) | Cytology | Cell Biology | Life Sciences
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2. Directed mutagenesis
: a practical approach
by McPherson, M. J
1991, Practical approach series., ISBN 9780199631414, xx, 257
Site-specific mutagenesis
Book
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3. In vitro mutagenesis protocols
by Braman, Jeff
2010, 3rd ed., Methods in molecular biology, ISBN 9781607616528, Volume 634., xiv, 442
Mutagenesis, Insertional | Mutagenesis, Site-Directed | Mutagenesis | Methodology | methods | Polymerase Chain Reaction
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4. Full Text Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf-/-mouse model
by Chapeau, Emilie A and Gembarska, Agnieszka and Durand, Eric Y and Mandon, Emeline and Estadieu, Claire and Romanet, Vincent and Wiesmann, Marion and Tiedt, Ralph and Lehar, Joseph and Weck, Antoine De and Rad, Roland and Barysb, Louise and Jeay, Sebastien and Ferretti, Stephane and Kauffmann, Audrey and Sutter, Esther and Grevot, Armelle and Moulin, Pierre and Murakami, Masato and Sellers, William R and Hofmann, Francesco and Jensena, Michael Rugaard
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2017, Volume 114, Issue 12, pp. 3151 - 3156
Inhibitors of double minute 2 protein (MDM2)-tumor protein 53 (TP53) interaction are predicted to be effective in tumors in which the TP53 gene is wild type,... 
PiggyBac screen | Drug resistance | Pancer | MDM2 inhibitor | MDM2 INHIBITORS | DRUG-COMBINATIONS | MULTIDISCIPLINARY SCIENCES | CANCER GENE DISCOVERY | SOMATIC MUTATIONS | P53 | piggyBac screen | PROSTATE-CANCER | CLINICAL-TRIALS | SLEEPING-BEAUTY | TUMOR-SUPPRESSOR | cancer | drug resistance | HIGHLY POTENT | Neoplasms - metabolism | Genetic Drift | Proto-Oncogene Proteins c-mdm2 - genetics | Tumor Suppressor Protein p53 - antagonists & inhibitors | Humans | bcl-X Protein - genetics | Biomarkers, Tumor | Tumor Suppressor Protein p53 - genetics | Allografts | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Antineoplastic Agents - pharmacology | Proto-Oncogene Proteins c-mdm2 - antagonists & inhibitors | Proto-Oncogene Proteins c-mdm2 - metabolism | Disease Models, Animal | Kaplan-Meier Estimate | Tumor Suppressor Protein p53 - metabolism | Neoplasms - mortality | Cell Transformation, Neoplastic - metabolism | DNA Transposable Elements | Genetic Vectors - genetics | Mice, Knockout | Drug Resistance, Neoplasm - genetics | Animals | Mice | Mutagenesis, Insertional | Neoplasms - pathology | bcl-X Protein - metabolism | Biological Sciences
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5. Full Text Targeted Mutagenesis, Precise Gene Editing, and Site-Specific Gene Insertion in Maize Using Cas9 and Guide RNA
by Sergei Svitashev and Joshua K. Young and Christine Schwartz and Huirong Gao and S. Carl Falco and A. Mark Cigan
Plant Physiology, ISSN 0032-0889, 10/2015, Volume 169, Issue 2, pp. 931 - 945
Targeted mutagenesis, editing of endogenous maize ( ) genes, and site-specific insertion of a trait gene using clustered regularly interspaced short... 
Genetic vectors | DNA | Genes | Guide RNA | Alleles | Corn | Genomes | Breakthrough Technologies | Plants | Genetic mutation | Embryos | CRISPR/CAS SYSTEM | AGROBACTERIUM-TUMEFACIENS | ARABIDOPSIS-THALIANA | GENOME MODIFICATION | DOUBLE-STRAND BREAKS | HOMING ENDONUCLEASES | HOMOLOGOUS RECOMBINATION | ZINC-FINGER NUCLEASES | SACCHAROMYCES-CEREVISIAE | DNA-BINDING SPECIFICITY | PLANT SCIENCES | Genetic Engineering - methods | Amino Acid Sequence | Zea mays - genetics | Mutagenesis, Insertional - methods | Molecular Sequence Data | Gene Knockout Techniques | Plant Proteins - genetics | Plant Breeding - methods | Clustered Regularly Interspaced Short Palindromic Repeats | Acetolactate Synthase - genetics | Agrobacterium - genetics | RNA, Guide | Mutation | Enzymes | Usage | Genetic aspects | Genetic engineering | Methods | Index Medicus
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6. In vitro mutagenesis protocols
by Trower, Michael K and SpringerLink (Online service)
1996, Methods in molecular biology, ISBN 9780896033320, Volume 57., xiv, 390
Mutagenesis, Site-Directed | Mutagenesis | Methodology | methods | Polymerase Chain Reaction | laboratory manuals | Mutagenesis, Insertional | Microbiology | Cytology | Cell Biology | Life Sciences
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7. Full Text Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas
by Nault, Jean-Charles and Datta, Shalini and Imbeaud, Sandrine and Franconi, Andrea and Mallet, Maxime and Couchy, Gabrielle and Letouzé, Eric and Pilati, Camilla and Verret, Benjamin and Blanc, Jean-Frédéric and Balabaud, Charles and Calderaro, Julien and Laurent, Alexis and Letexier, Mélanie and Bioulac-Sage, Paulette and Calvo, Fabien and Zucman-Rossi, Jessica
Nature Genetics, ISSN 1061-4036, 09/2015, Volume 47, Issue 10, pp. 1187 - 1193
Hepatocellular carcinomas (HCCs) are liver tumors related to various etiologies, including alcohol intake and infection with hepatitis B (HBV) or C (HCV)... 
TRANSFORMATION | NEUTRALIZING ANTIBODIES | INTEGRATION | RNA-SEQ | GENETICS & HEREDITY | ADENOASSOCIATED VIRUS AAV | GENE-THERAPY | DEFECTIVE VIRUS | LIVER CANCERS | SOMATIC MUTATIONS | VECTOR | Dependovirus - genetics | Oncogene Proteins - genetics | Telomerase - genetics | Liver Neoplasms - genetics | Carcinoma, Hepatocellular - genetics | Humans | Molecular Sequence Data | Cyclin A2 - genetics | Mutagenesis, Insertional | Virus Integration | Cyclin E - genetics | TNF-Related Apoptosis-Inducing Ligand - genetics | Gene mutations | Development and progression | Genetic aspects | Disease susceptibility | Hepatoma | Dependoviruses | Identification and classification | Health aspects | Index Medicus
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8. Full Text Essential roles for imuA' - and imuB -encoded accessory factors in DnaE2-dependent mutagenesis in Mycobacterium tuberculosis
by Digby F. Warner and Duduzile E. Ndwandwe and Garth L. Abrahams and Bavesh D. Kana and Edith E. Machowski and Česlovas Venclovas and Valerie Mizrahi and Stephen J. Benkovic
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2010, Volume 107, Issue 29, pp. 13093 - 13098
In Mycobacterium tuberculosis (Mtb), damage-induced mutagenesis is dependent on the C-family DNA polymerase, DnaE2. Included with dnaE2 in the Mtb SOS regulon... 
Proteins | Phenotypes | Mutagenesis | Mycobacterium tuberculosis | DNA | DNA damage | Immune tolerance | Lesions | Genetic mutation | Truncation | Mycobacterium smegmatis | Induced mutagenesis | Y-family polymerase | Drug resistance | ALPHA-SUBUNIT | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | CRYSTAL-STRUCTURES | DNA-POLYMERASE-III | DRUG-RESISTANCE | induced mutagenesis | SITE-SPECIFIC INTEGRATION | PROOFREADING FUNCTION | EXONUCLEASE ACTIVITY | ERROR-PRONE | drug resistance | LESION-BYPASS | Amino Acid Sequence | Catalytic Domain | Biocatalysis | Protein Structure, Secondary | Bacterial Proteins - chemistry | Molecular Sequence Data | Structure-Activity Relationship | Mutagenesis, Insertional - genetics | Amino Acid Motifs | Mycobacterium tuberculosis - enzymology | Protein Binding | Bacterial Proteins - metabolism | DNA Damage | DNA-Directed DNA Polymerase - metabolism | Drug resistance in microorganisms | DNA polymerases | Research | Diagnosis | Properties | Index Medicus | Pathogens | Amino acids | Data processing | Operons | Actinomycetes | Genomes | Gene deletion | Protein interaction | DNA-directed DNA polymerase | Deletion mutant | Biological Sciences
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9. Full Text Transposon mutagenesis
by Kulasekara, Hemantha D
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2014, Volume 1149, pp. 501 - 519
Transposon-based mutagenesis of bacterial genomes is a powerful method to identify genetic elements that control specific phenotypes. The most frequently used... 
Mariner mutagenesis | Pseudomonas aeruginosa | Arbitrary PCR | Transposon mutagenesis | Himar1 mariner | Phenotype | Reproducibility of Results | Mutagenesis, Insertional - methods | Pseudomonas aeruginosa - genetics | Nucleotide Motifs - genetics | DNA Transposable Elements - genetics | Polymerase Chain Reaction | Genetic Vectors - metabolism | Mutation - genetics | Sequence Analysis, DNA
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10. In vitro mutagenesis
: methods and protocols
by Reeves, Andrew (Andrew R.)
2017, Methods in molecular biology, ISBN 1493964720, Volume 1498
Mutagenesis, Site-Directed | methods | Mutagenesis, Insertional | Gene Editing | DNA Transposable Elements
Web Resource
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11. In vitro mutagenesis
: methods and protocols
by Reeves, Andrew (Andrew R.)
2017, Methods in molecular biology, ISBN 1493964720, Volume 1498
Mutagenesis, Site-Directed | methods | Mutagenesis, Insertional | Gene Editing | DNA Transposable Elements
Web Resource
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12. Full Text CRISPR-Cas9 targeted mutagenesis leads to simultaneous modification of different homoeologous gene copies in polyploid oilseed rape (Brassica napus)
by Braatz, Janina and Harloff, Hans-Joachim and Mascher, Martin and Stein, Nils and Himmelbach, Axel and Jung, Christian
Plant Physiology, ISSN 0032-0889, 06/2017, Volume 174, Issue 2, pp. 935 - 942
In polyploid species, altering a trait by random mutagenesis is highly inefficient due to gene redundancy. We have stably transformed tetraploid oilseed rape... 
RNA-GUIDED CAS9 | SPECIFICITY | BARLEY | PLANTS | MUTATIONS | ARABIDOPSIS | PLANT SCIENCES | Transformation, Genetic | Gene Targeting | Polyploidy | Brassica napus - genetics | Seeds - genetics | Gene Dosage | Genome, Plant | Mutation - genetics | CRISPR-Cas Systems - genetics | Sequence Homology, Nucleic Acid | Mutagenesis, Insertional - genetics | DNA, Bacterial - genetics | Base Sequence | Inheritance Patterns - genetics | Brassica napus - growth & development | Botanical research | Rape (Plant) | Physiological aspects | Plant mutation | Genetic aspects | Research | Nucleotide sequencing | Methods | DNA sequencing
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13. Full Text Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana
by José M. Alonso and Anna N. Stepanova and Thomas J. Leisse and Christopher J. Kim and Huaming Chen and Paul Shinn and Denise K. Stevenson and Justin Zimmerman and Pascual Barajas and Rosa Cheuk and Carmelita Gadrinab and Collen Heller and Albert Jeske and Eric Koesema and Cristina C. Meyers and Holly Parker and Lance Prednis and Yasser Ansari and Nathan Choy and Hashim Deen and Michael Geralt and Nisha Hazari and Emily Hom and Meagan Karnes and Celene Mulholland and Ral Ndubaku and Ian Schmidt and Plinio Guzman and Laura Aguilar-Henonin and Markus Schmid and Detlef Weigel and David E. Carter and Trudy Marchand and Eddy Risseeuw and Debra Brogden and Albana Zeko and William L. Crosby and Charles C. Berry and Joseph R. Ecker
Science, ISSN 0036-8075, 8/2003, Volume 301, Issue 5633, pp. 653 - 657
Over 225,000 independent Agrobacterium transferred DNA (T-DNA) insertion events in the genome of the reference plant Arabidopsis thaliana have been created... 
Yeasts | Neuroscience | Neurons | Genes | DNA | Reports | Genomes | Plants | Hormones | Chromosomes | Genetic mutation | MULTIDISCIPLINARY SCIENCES | Oligonucleotide Array Sequence Analysis | Exons | Genes, Plant | Gene Expression Profiling | Arabidopsis Proteins - metabolism | DNA, Plant - chemistry | Recombination, Genetic | 3' Untranslated Regions | Ethylenes - pharmacology | DNA, Plant - genetics | Expressed Sequence Tags | Promoter Regions, Genetic | Arabidopsis Proteins - genetics | Gene Expression | Introns | Genome, Plant | Arabidopsis - metabolism | Rhizobium - genetics | Arabidopsis - genetics | Gene Expression Regulation, Plant - drug effects | DNA, Bacterial - genetics | 5' Untranslated Regions | Base Composition | Alleles | Mutagenesis, Insertional | Mutation | Chromosomes, Plant - genetics | Flowers & plants | Genomics | Deoxyribonucleic acid--DNA
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14. Full Text Gene Therapy Insertional Mutagenesis Insights
by Utpal P. Davé and Nancy A. Jenkins and Neal G. Copeland
Science, ISSN 0036-8075, 1/2004, Volume 303, Issue 5656, pp. 333 - 333
In a milestone study describing the first "cure" of a genetic disease by retroviral gene therapy, nine out of ten infants born with X-linked severe combined... 
Exons | Leukemia | Cell lines | Insertional mutagenesis | Viruses | Gene therapy | Oncogenes | Tumors | Brevia | SEVERE COMBINED IMMUNODEFICIENCY | MULTIDISCIPLINARY SCIENCES | LEUKEMIA | Gene Expression | LIM Domain Proteins | Humans | Leukemia, T-Cell - etiology | Severe Combined Immunodeficiency - therapy | DNA-Binding Proteins - genetics | Virus Integration | Receptors, Interleukin-2 - genetics | Severe Combined Immunodeficiency - genetics | Adaptor Proteins, Signal Transducing | Animals | Leukemia, T-Cell - genetics | Retroviridae - genetics | Metalloproteins - genetics | Mice | Mutagenesis, Insertional | Proto-Oncogene Proteins | Genetic Vectors | Genetic Therapy - adverse effects | Clinical trials | Mutation
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15. Retroviral insertion and oncogene activation
by Kung, H. J and Vogt, P. K
1991, Current topics in microbiology and immunology, ISBN 9783540538578, Volume 171., vi, 179
Oncogènes | Retroviruses | Rétrovirus | Cancérogenèse virale | Oncogenes | Viral carcinogenesis
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16. Full Text Large‐scale insertional mutagenesis using the Tnt1 retrotransposon in the model legume Medicago truncatula
by Tadege, Million and Wen, Jiangqi and He, Ji and Tu, Haidi and Kwak, Younsig and Eschstruth, Alexis and Cayrel, Anne and Endre, Gabriella and Zhao, Patrick X and Chabaud, Mireille and Ratet, Pascal and Mysore, Kirankumar S
The Plant Journal, ISSN 0960-7412, 04/2008, Volume 54, Issue 2, pp. 335 - 347
Summary Medicago truncatula is a fast‐emerging model for the study of legume functional biology. We used the tobacco retrotransposon Tnt1 to tag the Medicago... 
Medicago | functional genomics | legume | retrotransposon | Tnt1 tagging | insertion mutagenesis | Retrotransposon | Insertion mutagenesis | Functional genomics | Legume | ARABIDOPSIS-THALIANA | TRANSPOSABLE ELEMENTS | T-DNA | TRANSPOSITION | PLANT SCIENCES | TOBACCO RETROTRANSPOSON | EVOLUTION | TOS17 RETROTRANSPOSON | GENETICS | RICE | Medicago truncatula - genetics | Phenotype | Mutagenesis, Insertional - methods | Genes, Plant - genetics | Medicago truncatula - growth & development | Retroelements - genetics | Legumes | Beans | Mimosaceae | Analysis | Models | Mutation | Genomics | Botany | Index Medicus
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17. Full Text Mechanisms of Retroviral Integration and Mutagenesis
by Cavazza, Alessia and Moiani, Arianna and Mavilio, Fulvio
Human Gene Therapy, ISSN 1043-0342, 02/2013, Volume 24, Issue 2, pp. 119 - 131
Gene transfer vectors derived from oncoretroviruses or lentiviruses are the most robust and reliable tools to stably integrate therapeutic transgenes in human... 
Reviews | MEDICINE, RESEARCH & EXPERIMENTAL | SITE SELECTION | SEVERE COMBINED IMMUNODEFICIENCY | CHRONIC GRANULOMATOUS-DISEASE | LENTIVIRAL VECTOR INTEGRATION | SCID-X1 GENE-THERAPY | ENGINEERED DONOR LYMPHOCYTES | HEMATOPOIETIC-CELLS | HIV-1 INTEGRASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | GENOME-WIDE ANALYSIS | STEM-CELL TRANSPLANTATION | Gene Transfer Techniques | Humans | Transcriptional Activation | Genetic Vectors - metabolism | Virus Integration | Cell Transformation, Neoplastic - metabolism | Genetic Vectors - genetics | Host-Pathogen Interactions | Retroviridae - metabolism | Retroviridae - genetics | Regulatory Elements, Transcriptional | Transcription, Genetic | Mutagenesis, Insertional | Cell Transformation, Neoplastic - pathology | Genome, Human | Evolution, Molecular | Index Medicus
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