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1. Full Text Integrative network analysis reveals molecular mechanisms of blood pressure regulation
by Huan, Tianxiao and Meng, Qingying and Saleh, Mohamed A and Norlander, Allison E and Joehanes, Roby and Zhu, Jun and Chen, Brian H and Zhang, Bin and Johnson, Andrew D and Ying, Saixia and Courchesne, Paul and Raghavachari, Nalini and Wang, Richard and Liu, Poching and O'Donnell, Christopher J and Vasan, Ramachandran and Munson, Peter J and Madhur, Meena S and Harrison, David G and Yang, Xia and Levy, Daniel and Int Consortium Blood Pressure GWAS and The International Consortium for Blood Pressure GWAS (ICBP)
Molecular Systems Biology, ISSN 1744-4292, 04/2015, Volume 11, Issue 4, pp. 1 - n/a
Genome‐wide association studies ( GWAS ) have identified numerous loci associated with blood pressure ( BP ). The molecular mechanisms underlying BP... 
systems biology | blood pressure | coexpression network | hypertension | gene expression | GLOBAL BURDEN | SPONTANEOUSLY HYPERTENSIVE-RATS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANGIOTENSIN-II | II-INDUCED HYPERTENSION | CARDIOVASCULAR-DISEASE | CORONARY-HEART-DISEASE | GLYCOGEN-SYNTHASE GENE | ADAPTER PROTEIN LNK | UP-REGULATION | Index Medicus
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2. Full Text Molecular differences in Alzheimer's disease between male and female patients determined by integrative network analysis
by Sun, Lin‐Lin and Yang, Song‐Lin and Sun, Hui and Li, Wei‐Da and Duan, Shu‐Rong
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 01/2019, Volume 23, Issue 1, pp. 47 - 58
Alzheimer's disease ( AD ) is a complex neurodegenerative disease and the most common cause of dementia among the elderly. There has been increasing... 
Alzheimer's disease | temporal and spatial patterns | integrative network | sex differences | ESTROGENS | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | COGNITIVE IMPAIRMENT | NEUROPROTECTION | DEFICIENCY | CELL BIOLOGY | METABOLISM | SEX-DIFFERENCES | APOE | GENDER-DIFFERENCES | ASSOCIATION | Elderly people | Brain | Genes | Crosstalk | Sex | Males | Kinases | Pathways | Cortex (parietal) | Network analysis | Gender aspects | Dementia disorders | Kinesin | Cortex (temporal) | Cortex (prefrontal) | Neurodegenerative diseases | Glycogen | Cortex (occipital) | Glycogen synthase kinase 3 | Sex differences | Gender differences | Cortex (visual) | Gene expression | Patients | Aspartoacylase | Superior parietal lobule | Alzheimers disease | Females | Glutamic acid receptors (metabotropic) | Elderly | Geriatrics | Original
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3. Full Text Network analysis and mechanisms of action of Chinese herb-related natural compounds in lung cancer cells
by Lin, Ting-Hsu and Lin, Ying-Ju and Liang, Wen-Miin and Chen, Chao-Jung and Chen, Jianxin and Tsang, Hsinyi and Chiou, Jian-Shiun and Liu, Xiang and Cheng, Chi-Fung and Liao, Chiu-Chu and Huang, Shao-Mei and Tsai, Fuu-Jen and Li, Te-Mao
Phytomedicine, ISSN 0944-7113, 05/2019, Volume 58, pp. 152893 - 152893
Chinese herbal medicines (CHMs) are a resource of natural compounds (ingredients) and their potential chemical derivatives with anticancer properties, some of... 
Chinese herbal medicine | Natural compound | Lung cancer | Network analysis | Apoptosis | GLABRIDIN | CHEMISTRY, MEDICINAL | LICOCHALCONE-A | MEDICINE | PLANT SCIENCES | URSOLIC ACID | IN-VITRO | INTEGRATIVE & COMPLEMENTARY MEDICINE | A549 CELLS | GROWTH | PHARMACOLOGY & PHARMACY | LICORICE ROOT | CYCLE
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4. Full Text How leader role identity influences the process of leader emergence: A social network analysis
by Kwok, Navio and Hanig, Samuel and Brown, Douglas J and Shen, Winny
The Leadership Quarterly, ISSN 1048-9843, 12/2018, Volume 29, Issue 6, pp. 648 - 662
Contemporary theories on leadership development emphasize the importance of having a leader identity in building leadership skills and functioning effectively... 
Social networks | Leader emergence | Leader identity | PERSONALITY | MANAGEMENT | STRUCTURAL-ANALYSIS | PSYCHOLOGY, APPLIED | INTEGRATIVE MODEL | JOB-SATISFACTION | POWER | CENTRALITY | INDIVIDUAL-DIFFERENCES | SELF-CONCEPT | ANTECEDENTS | Leadership | Analysis | Crowdsourcing | Talent management | Leadership training
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5. Full Text Network analyses identify liver‐specific targets for treating liver diseases
by Lee, Sunjae and Zhang, Cheng and Liu, Zhengtao and Klevstig, Martina and Mukhopadhyay, Bani and Bergentall, Mattias and Cinar, Resat and StÄhlman, Marcus and Sikanic, Natasha and Park, Joshua K and Deshmukh, Sumit and Harzandi, Azadeh M and Kuijpers, Tim and GrÞtli, Morten and ElsÀsser, Simon J and Piening, Brian D and Snyder, Michael and Smith, Ulf and Nielsen, Jens and BÀckhed, Fredrik and Kunos, George and Uhlen, Mathias and Boren, Jan and Mardinoglu, Adil and Science for Life Laboratory, SciLifeLab and KTH and Centra
Molecular Systems Biology, ISSN 1744-4292, 08/2017, Volume 13, Issue 8, pp. 938 - n/a
We performed integrative network analyses to identify targets that can be used for effectively treating liver diseases with minimal side effects. We first... 
HCC | NAFLD | co‐regulation | metabolism | co‐expression | co-expression | co-regulation | PROTEOME | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTAGONISM | GLUTATHIONE METABOLISM | INSULIN | HEPATIC CB1 RECEPTORS | FATTY-ACID SYNTHASE | EXPRESSION | GENOME-SCALE | SYSTEMS BIOLOGY | REVEALS | Fatty Acid Synthase, Type I - genetics | Liver Neoplasms - genetics | Non-alcoholic Fatty Liver Disease - genetics | Humans | Cells, Cultured | Gene Expression Regulation | Liver Neoplasms - drug therapy | Gene Expression Profiling | Gene Regulatory Networks - drug effects | Molecular Targeted Therapy | Organ Specificity | Liver - chemistry | Hep G2 Cells | Non-alcoholic Fatty Liver Disease - drug therapy | Protein Interaction Maps | Systems Biology - methods | Animals | Carcinoma, Hepatocellular - drug therapy | Sequence Analysis, RNA | Liver - drug effects | Carcinoma, Hepatocellular - genetics | K562 Cells | Mice | Biotechnology | Target recognition | Pathogenesis | Liver | Genes | Central nervous system | Pyruvic acid | Hepatocellular carcinoma | Drug development | Tissues | Human tissues | Liver cancer | Cell growth | Fatty liver | Rodents | Inhibition | Lipogenesis | Liver diseases | Pyruvate kinase | Blood cells | Subtilisin | Tumor cell lines | Gene expression | Fatty acids | Fatty-acid synthase | Diseases | Phospholipase | Side effects | Kexin | Hepatocytes | Predictions | Cancer | Index Medicus | Medical Biotechnology | Medical and Health Sciences | Medicin och hĂ€lsovetenskap | Medicinsk bioteknologi
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6. Full Text Research trends in Korean medicine based on temporal and network analysis
by Kim, SK and Oh, Y and Nam, S
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, ISSN 1472-6882, 07/2019, Volume 19, Issue 1, pp. 160 - 160
BackgroundMuch research on Korean medicine has been recently published in Korea. The aim of this study was to determine the research trends in Korean medicine... 
Korean medicine | Temporal analysis | OXIDATIVE STRESS | OASIS | ACUPUNCTURE | INTEGRATIVE & COMPLEMENTARY MEDICINE | Network analysis | Trend analysis | HEALTH | Social networks | Medicine, Herbal | Acupuncture | Medicine, Botanic | Analysis
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7. Full Text System network analysis of genomics and transcriptomics data identified type 1 diabetes-associated pathway and genes
by Lu, Jun-Min and Chen, Yuan-Cheng and Ao, Zeng-Xin and Shen, Jie and Zeng, Chun-Ping and Lin, Xu and Peng, Lin-Ping and Zhou, Rou and Wang, Xia-Fang and Peng, Cheng and Xiao, Hong-Mei and Zhang, Kun and Deng, Hong-Wen
Genes and Immunity, ISSN 1466-4879, 2018, Volume 20, Issue 6, pp. 500 - 508
Genome-wide association studies (GWASs) have discovered >50 risk loci for type 1 diabetes (T1D). However, those variations only have modest effects on the... 
AUTOIMMUNE | INTEGRATIVE ANALYSIS | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | RAC GTPASES | MECHANISMS | WIDE ASSOCIATION | IMMUNOLOGY | EXPRESSION | BLOOD MONONUCLEAR-CELLS | DEFICIENCY | TELOMERE LENGTH | Molecular modelling | Statistical analysis | Immune response | DNA microarrays | Etiology | Diabetes mellitus | Genomics | Heritability | Diabetes mellitus (insulin dependent) | Diabetes | Gene expression | Index Medicus
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8. Full Text Coexpression network analysis identifies transcriptional modules related to proastrocytic differentiation and sprouty signaling in glioma
by Ivliev, Alexander E and 'T Hoen, Peter A. C and Sergeeva, Marina G
Cancer Research, ISSN 0008-5472, 12/2010, Volume 70, Issue 24, pp. 10060 - 10070
Gliomas are primary brain tumors with high mortality and heterogeneous biology that is insufficiently understood. In this study, we performed a systematic... 
GLIOBLASTOMA | ONCOLOGY | INTEGRATIVE ANALYSIS | EPIDERMAL-GROWTH-FACTOR | GENE-EXPRESSION | MALIGNANT GLIOMAS | CLASSIFICATION | FACTOR RECEPTOR | CANCER | MICROARRAY DATA | PROGRESSION | Astrocytoma - genetics | Receptor, Epidermal Growth Factor - genetics | Brain Neoplasms - enzymology | Glioma - enzymology | Oligodendroglioma - genetics | Humans | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Brain Neoplasms - genetics | Gene Expression Profiling | Signal Transduction - genetics | Oligodendroglioma - enzymology | Gene Regulatory Networks | Glioma - genetics | Cell Differentiation - genetics | Astrocytoma - pathology | Receptor, Epidermal Growth Factor - metabolism | Algorithms | Gene Amplification | Oligodendroglioma - pathology | Glioma - pathology | Astrocytoma - enzymology | Index Medicus
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9. Full Text Broad range metabolomics coupled with network analysis for explaining possible mechanisms of Er-Zhi-Wan in treating liver-kidney Yin deficiency syndrome of Traditional Chinese medicine
by Zhai, Yuanyuan and Xu, Jia and Feng, Li and Liu, Qinan and Yao, Weifeng and Li, Hui and Cao, Yudan and Cheng, Fangfang and Bao, Beihua and Zhang, Li
Journal of Ethnopharmacology, ISSN 0378-8741, 04/2019, Volume 234, pp. 57 - 66
Er-Zhi-Wan (EZW), a famous traditional Chinese formulation, is used to prevent, or to treat, various liver and kidney diseases for its actions of replenishing... 
Urine | Serum | Er-Zhi-Wan | Broad range metabolomics | Liver-kidney Yin deficiency syndrome | Network analysis | METABONOMICS | CHEMISTRY, MEDICINAL | ACID | PERSPECTIVE | CHROMATOGRAPHY | PLANT SCIENCES | DIABETES-MELLITUS | PLASMA | INTEGRATIVE & COMPLEMENTARY MEDICINE | PHARMACOLOGY & PHARMACY | PARTIAL LEAST-SQUARES | Liver diseases | Metabolites | Analysis | Liver | Medicine, Chinese | Thyroid hormones | Kidney diseases | Index Medicus
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10. Full Text Neural network analysis of Chinese herbal medicine prescriptions for patients with colorectal cancer
by Lin, Yu-Chuan and Lin, Sheng-Shing and Lin, Hung-Jen and Huang, Wei-Te and Huang, Sheng-Teng and Ou, Shi-Chen and Hung, Hao-Hsiu and Cheng, Wie-Zen
Complementary Therapies in Medicine, ISSN 0965-2299, 02/2019, Volume 42, pp. 279 - 285
Traditional Chinese Medicine (TCM) is an experiential form of medicine with a history dating back thousands of years. The present study aimed to utilize neural... 
Traditional Chinese medicine | Chinese herbal medicine | Neural network analysis | Colorectal cancer | Machine learning | PAEONIA-LACTIFLORA | GROWTH-INHIBITION | INDUCED APOPTOSIS | RADIX | KNOWLEDGE DISCOVERY | COLON | TANSHINONE I | ORPHAN NUCLEAR RECEPTOR | INTEGRATIVE & COMPLEMENTARY MEDICINE | DIFFUSA-WILLD EXTRACT | CELL-LINE | Colorectal Neoplasms - drug therapy | Humans | Software | Medicine, Chinese Traditional - methods | Drug Prescriptions | Drugs, Chinese Herbal - therapeutic use | Databases, Factual | Neural Networks (Computer) | Physicians | Colorectal carcinoma | Standardization | Medical records | Chinese medicine | Pain | Moisture content | Education | Network analysis | Prescriptions | Herbs | Appetite | Medical personnel | Medical research | Big Data | Fatigue | Data processing | Patients | Doctors | Computer programs | Herbal medicine | Medicine | Learning algorithms | Neural networks | Clinical medicine | Artificial intelligence | Cancer | Index Medicus
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11. Full Text Synergistic Effects of Sanghuang⁻Danshen Bioactives on Arterial Stiffness in a Randomized Clinical Trial of Healthy Smokers: An Integrative Approach to in silico Network Analysis
by Lim, Yeni and Song, Tae-Jin and Song, Tae-Jin and Hwang, Woochang and Hwang, Woochang and Kim, Ji Yeon and Kim, Ji Yeon and Lee, Doheon and Lee, Doheon and Kim, Yong-Jae and Kim, Yong-Jae and Kwon, Oran and Kwon, Oran
Nutrients, ISSN 2072-6643, 01/2019, Volume 11, Issue 1, p. 108
The vascular endothelium is a favorite early target of cardiovascular risk factors, including cigarette smoking. Here, we investigated the synergistic effects... 
arterial stiffness | in silico network analysis | endothelium-dependent vasodilation | integrative approach | randomized clinical trial | Sanghuang mushroom | Danshen | OXIDATIVE STRESS | PULSE-WAVE VELOCITY | ENDOTHELIAL DYSFUNCTION | PREVENTS | BLOOD-PRESSURE | CIGARETTE-SMOKING | NUTRITION & DIETETICS | METABOLISM | DISEASE | HYPERTENSION | Metabolomics | Plant Extracts - chemistry | Gene Expression - drug effects | Pulse Wave Analysis | Proline - metabolism | Humans | Endothelium, Vascular - drug effects | Male | Plant Extracts - administration & dosage | Placebos | Adult | Female | Blood Pressure - drug effects | Nitric Oxide Synthase Type III - metabolism | Smokers | Double-Blind Method | Fruit - chemistry | Basidiomycota - chemistry | Enzyme Activation - drug effects | Drug Synergism | Salvia miltiorrhiza - chemistry | Endothelium, Vascular - metabolism | Vascular Stiffness - drug effects | Tobacco Smoking - adverse effects | Vasodilation - drug effects | Arginine - metabolism | Index Medicus
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12. Full Text Integrative Bayesian Network Analysis of Genomic Data
by Yang Ni and Francesco C. Stingo and Veerabhadran Baladandayuthapani
Cancer Informatics, ISSN 1176-9351, 09/2014, Volume 2014, Issue Suppl. 2, pp. 39 - 48
Rapid development of genome-wide profiling technologies has made it possible to conduct integrative analysis on genomic data from multiple platforms. In this... 
Integrative analysis | Bayesian network | Glioblastoma multiforme | Multiple platforms | Epigenetic inheritance | Criminal investigation | Analysis | Genomics | Genetic research | Models | Genomes
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