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PLoS pathogens, ISSN 1553-7374, 11/2013, Volume 9, Issue 11, pp. e1003773 - e1003773
Interferons (IFNs) are a group of cytokines with a well-established antiviral function. They can be induced by viral infection, are secreted and bind to... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Epithelial Cells - metabolism | Influenza A virus - genetics | Respiratory Mucosa - virology | Interferon Regulatory Factor-7 - genetics | Interferon Type I - immunology | Interferon Regulatory Factor-3 - genetics | Interleukins - metabolism | Orthomyxoviridae Infections - genetics | Respiratory Mucosa - pathology | Interleukins - genetics | Interleukins - immunology | Respiratory Mucosa - immunology | Adaptor Proteins, Signal Transducing - immunology | Interferon Type I - metabolism | Influenza A virus - immunology | Membrane Proteins - metabolism | Interferon Regulatory Factor-3 - immunology | Nerve Tissue Proteins - immunology | Membrane Proteins - genetics | Orthomyxoviridae Infections - metabolism | Epithelial Cells - pathology | Membrane Proteins - immunology | Interferon Regulatory Factor-7 - immunology | Interferon Regulatory Factor-7 - metabolism | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Influenza A virus - metabolism | Epithelial Cells - immunology | Epithelial Cells - virology | Adaptor Proteins, Signal Transducing - genetics | Interferon Regulatory Factor-3 - metabolism | Interferon Type I - genetics | Mice | Respiratory Mucosa - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Orthomyxoviridae Infections - immunology | Epithelial cells | Influenza | Physiological aspects | Host-parasite relationships | Interferon | Genetic aspects | Genetic transcription | Research | Health aspects | Airway (Medicine) | Index Medicus | Interleukins/metabolism | Nerve Tissue Proteins/immunology | Orthomyxoviridae Infections/genetics | Orthomyxoviridae Infections/metabolism | Membrane Proteins/genetics | Adaptor Proteins, Signal Transducing/genetics | Interferon Regulatory Factor-7/genetics | Interleukins/immunology | Membrane Proteins/immunology | Life Sciences | Orthomyxoviridae Infections/immunology | Influenza A virus/genetics | Nerve Tissue Proteins/metabolism | Respiratory Mucosa/immunology | Immunology | Interferon Type I/immunology | Epithelial Cells/immunology | Epithelial Cells/virology | Interferon Regulatory Factor-7/immunology | Epithelial Cells/metabolism | Interferon Regulatory Factor-3/immunology | Respiratory Mucosa/pathology | Influenza A virus/immunology | Interleukins/genetics | Interferon Regulatory Factor-3/genetics | Influenza A virus/metabolism | Adaptor Proteins, Signal Transducing/metabolism | Epithelial Cells/pathology | Adaptor Proteins, Signal Transducing/immunology | Interferon Type I/genetics | Interferon Regulatory Factor-3/metabolism | Membrane Proteins/metabolism | Nerve Tissue Proteins/genetics | Interferon Regulatory Factor-7/metabolism | Interferon Type I/metabolism | Respiratory Mucosa/metabolism | Respiratory Mucosa/virology | Cytokines | Genes | Rodents | Genomics | Genomes | Kinases | Experiments | Viral infections
Journal Article
Journal of virology, ISSN 1098-5514, 09/2012, Volume 86, Issue 18, pp. 9888 - 9898
Chikungunya virus (CHIKV) infections can produce severe disease and mortality. Here we show that CHIKV infection of adult mice deficient in interferon response... 
Life Sciences & Biomedicine | Science & Technology | Virology | Interferon-alpha - pharmacology | Shock, Hemorrhagic - prevention & control | Humans | Adaptor Proteins, Vesicular Transport - deficiency | Adaptor Proteins, Vesicular Transport - genetics | Receptor, Interferon alpha-beta - physiology | Interferon Regulatory Factor-7 - genetics | Interferon Regulatory Factor-3 - genetics | Host-Pathogen Interactions - immunology | Alphavirus Infections - prevention & control | Interferon Regulatory Factor-7 - physiology | Chikungunya virus - physiology | Receptor, Interferon alpha-beta - genetics | Chikungunya virus - pathogenicity | Chikungunya Fever | Virus Replication - drug effects | Adaptor Proteins, Vesicular Transport - physiology | Interferon-alpha - biosynthesis | Receptor, Interferon alpha-beta - deficiency | Mice, Inbred C57BL | Myeloid Differentiation Factor 88 - genetics | Interferon-beta - biosynthesis | Alphavirus Infections - immunology | Chikungunya virus - immunology | Alphavirus Infections - pathology | Interferon Regulatory Factor-3 - physiology | Mice, Knockout | Animals | Interferon Regulatory Factor-3 - deficiency | Myeloid Differentiation Factor 88 - deficiency | Host-Pathogen Interactions - genetics | Interferon Regulatory Factor-7 - deficiency | Myeloid Differentiation Factor 88 - physiology | Mice | Shock, Hemorrhagic - immunology | Index Medicus | Life Sciences | Santé publique et épidémiologie | Pathogenesis and Immunity
Journal Article
Cytokine & growth factor reviews, ISSN 1359-6101, 04/2015, Volume 26, Issue 2, pp. 103 - 111
Abstract Interferons (IFN) are key cytokines with multifaceted antiviral and cell-modulatory properties. Three distinct types of IFN are recognized (I–III)... 
Advanced Basic Science | Interferon types I–III | Interferon–interferon interactions | Interferon genes and receptors | Anti-interferon strategies | Interferon types I-III | Interferon-interferon interactions | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Proliferation | Virus Diseases - immunology | Signal Transduction | Antiviral Agents - immunology | Humans | Transcriptional Activation | Interferon-gamma - physiology | Receptor, Interferon alpha-beta - physiology | Virus Diseases - virology | Interferon Type I - immunology | Interferons - immunology | Genetic Variation | Interferon Type I - genetics | Cell Differentiation | Interferon Type I - physiology | Interferons - physiology | Interferons - genetics | Virus diseases | Interferon | Biological response modifiers | Health aspects | Genetic polymorphisms | IRF, interferon regulatory factor | WNV, West Nile virus | ADAR1, adenosine deaminase acting on RNA 1 | CREB-binding protein | IPS-1, interferon promoter-stimulating factor 1 | EM, environmental mycobacteria | HSE, herpes simplex encephalitis | NEMO, nuclear factor (NF)-kB essential modulator | hCMV, human Cytomegalovirus | APCs, antigen presenting cells | NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells | IRAK-4, interleukin-1 receptor-associated kinase 4 | ds, double strand | SARS, severe acute respiratory syndrome | GAS, gamma interferon activation site | ss, single strand | IFI16, gamma-interferon-inducible protein 16 | TREX1, three prime repair exonuclease 1 | Th, lymphocytes T helper | p300 | PKR, dsRNA-dependent protein kinase | TYK2, tyrosine kinase 2 | IL, interleukin | CRF2, class II cytokine receptor family | IFNGR, interferon gamma receptor | ISGF3, interferon-stimulated gene factor 3 | CHIKV, Chickungunya virus | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | HCV, hepatitis C virus | ATF6, activating transcription factor 6 | EAE, experimental allergic encephalomyelitis | MSMD, Mendelian susceptibility to mycobacterial disease | MxA, Myxovirus Resistance Gene A | RIG-1, retinoic-acid-inducible gene 1 | CBP, chromatin remodeling associated p300 | AP-1, activator protein 1 | OAS, 2′,5′-oligo adenylate synthetase A | HSV-1, herpes simplex virus-1 | SAMHD1, SAM domain and HD domain-containing protein 1 | SARS-CoV, severe acute respiratory syndrome-associated coronavirus | STAT, Signal Transducer and Activator of Transcription | VZV, Varicella-Zoster virus | IFN, interferon | VSV, vesicular stomatitis virus | LASV, Lassa virus | cGAS, cyclic GMP-AMP synthase | ISRE, interferon stimulated response element | EMCV, encephalomyocarditis virus | IFNAR, interferon alpha receptor | BCG, bacille Calmette–Guérin | MHC, major histocompatibility complex | MS, multiple sclerosis | SNPs, single nucleotide polymorphisms | PD-L1, programmed death ligand 1 | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | MAPK, mitogen-activated protein kinases | NK, natural killer cells | PRRs, pattern-recognition receptors
Journal Article
Journal of biological regulators and homeostatic agents, ISSN 0393-974X, 1987
Journal
1984, 1, ISBN 9780849355424, 191
This book reviews advances made in recombinant DNA technology as it relates to the techniques employed, and the production and testing of potentially important... 
Somatotropin | Biological products | Interferons | DNA, Recombinant | Genetic engineering | Biosynthesis | Recombinant DNA | Insulin | Biotechnology
Book
Journal of virology, ISSN 0022-538X, 04/2007, Volume 81, Issue 13, pp. 7011 - 7021
Journal Article
Journal Article
2005, Routledge studies in the history of science, technology & medicine, ISBN 0415342465, xvi, 264
This innovative study charts the beginnings, history and fate of Interferon - one of modern medicine's most famous and infamous drugs. Interferon is part of... 
History | Interferon industry | Interferon
Book