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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2011, Volume 108, Issue 4, pp. 1456 - 1461
Primary cilia are required for proper Sonic Hedgehog (Shh) signaling in mammals. However, their role in the signal transduction process remains unclear. We... 
Hedgehogs | Phenotypes | Neurons | Gene expression regulation | Physiological regulation | Genetic mutation | Embryos | Cells | Regulator genes | Cilia | Kinesin 2 | Cytoplasmic dynein 2 | Axoneme | Neural patterning | CELL BODY | MULTIDISCIPLINARY SCIENCES | MOUSE | NEURAL-TUBE | TRANSDUCTION | PRIMARY CILIUM | GLI3 | NEGATIVE REGULATOR | neural patterning | cytoplasmic dynein 2 | CAENORHABDITIS-ELEGANS | axoneme | KINESIN-II | IFT | kinesin 2 | Immunohistochemistry | Receptors, G-Protein-Coupled - metabolism | Zinc Finger Protein Gli2 | Zinc Finger Protein Gli3 | Hedgehog Proteins - metabolism | Male | Green Fluorescent Proteins - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Embryo, Mammalian - metabolism | In Situ Hybridization | Hedgehog Proteins - genetics | Gene Expression Regulation, Developmental | Kruppel-Like Transcription Factors - metabolism | Mice, Mutant Strains | Smoothened Receptor | Cilia - ultrastructure | Female | Intracellular Signaling Peptides and Proteins - genetics | Fibroblasts - metabolism | Green Fluorescent Proteins - metabolism | Microscopy, Electron, Scanning | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Nerve Tissue Proteins - genetics | Blotting, Western | Cilia - metabolism | Mice, Inbred C3H | Cilia - genetics | Nerve Tissue Proteins - metabolism | Proteins - genetics | Animals | Proteins - metabolism | Embryo, Mammalian - embryology | Embryo, Mammalian - cytology | Fibroblasts - cytology | Mice | Receptors, G-Protein-Coupled - genetics | Kruppel-Like Transcription Factors - genetics | Microscopy, Fluorescence | Physiological aspects | Cellular signal transduction | Genetic aspects | Research | Carrier proteins | Flagella (Microbiology) | Biological Sciences
Journal Article
Journal Article
eLife, ISSN 2050-084X, 03/2014, Volume 2014, Issue 3, p. e01566
Journal Article