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International Journal of Nanomedicine, ISSN 1176-9114, 12/2016, Volume 11, pp. 6575 - 6590
Purpose: Along with their cholesterol-lowering effect, statins have shown a wide range of pleiotropic effects potentially beneficial to neurodegenerative... 
Nanoparticles | Neurodegenerative diseases | Biodegradable nanoparticles | Gamma scintigraphy | Simvastatin | Small-angle X-ray scattering (SAXS) | Lysozyme | Nose-to-brain | NANOPARTICLE TRACKING ANALYSIS | lysozyme | small-angle X-ray scattering (SAXS) | ALZHEIMERS-DISEASE | simvastatin | biodegradable nanoparticles | NANOSCIENCE & NANOTECHNOLOGY | nose-to-brain | APOLIPOPROTEIN-E | PHYSICOCHEMICAL PROPERTIES | neurodegenerative diseases | IN-VITRO | nanoparticles | ANALYSIS NTA | INTRANASAL DRUG-DELIVERY | PHARMACOLOGY & PHARMACY | gamma scintigraphy | CENTRAL-NERVOUS-SYSTEM | ELASTIC NEUTRON-SCATTERING | LECITHIN/CHITOSAN NANOPARTICLES | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Nanoparticles - chemistry | Rats, Wistar | Simvastatin - administration & dosage | Nanoparticles - ultrastructure | Rats | Male | Simvastatin - pharmacology | Administration, Intranasal | Drug Delivery Systems | Brain - drug effects | Brain - metabolism | Microscopy, Electron, Scanning Transmission | Particle Size | Tissue Distribution | Animals | Chitosan - chemistry | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Drug Liberation | Nanoparticles - administration & dosage | Nasal Mucosa - metabolism | Nasal Mucosa - drug effects | Lecithin | Nervous system diseases | Drugs | Enzymes | Lipids | Permeability | Metabolism | Cholesterol | Proteins | Brain research | Metabolites | Pharmacy | Nose | Alzheimers disease | Statins | Neurodegenerative | Nasal delivery
Journal Article
Advanced Drug Delivery Reviews, ISSN 0169-409X, 12/2016, Volume 107, pp. 163 - 175
Journal Article
1989, ISBN 9780824780937, vii, 310
Book
Current Opinion in Colloid & Interface Science, ISSN 1359-0294, 10/2012, Volume 17, Issue 5, pp. 306 - 313
Journal Article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, ISSN 0022-3565, 09/2019, Volume 370, Issue 3, pp. 593 - 601
The global prevalence of neurologic disorders is rising, and yet we are still unable to deliver most drug molecules, in therapeutic quantities, to the brain.... 
INSULIN | SYSTEM | DRUG-DELIVERY | ALZHEIMERS-DISEASE | OXYTOCIN | DISORDER | PHARMACOLOGY & PHARMACY | INTRANASAL DELIVERY | ABSORPTION | PLGA NANOPARTICLES | LOADED CHITOSAN NANOPARTICLES | Index Medicus
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 06/2015, Volume 207, pp. 18 - 30
Exosomes are naturally occurring nanosized vesicles that have attracted considerable attention as drug delivery vehicles in the past few years. Exosomes are... 
Oxidative stress | Neuroinflammation | Parkinson's disease | Catalase | Exosomes | Blood–brain barrier | Blood-brain barrier | ALZHEIMERS-DISEASE | REPEATED INJECTIONS | MACROPHAGE DELIVERY | MEDIATED TRANSFER | BLOOD-BRAIN-BARRIER | BIOLOGICAL BARRIERS | CHEMISTRY, MULTIDISCIPLINARY | IN-VITRO | PEGYLATED LIPOSOMES | PHARMACOLOGY & PHARMACY | SUPEROXIDE-DISMUTASE | Antioxidants - chemistry | Antioxidants - metabolism | Oxidopamine | Anti-Inflammatory Agents - metabolism | PC12 Cells | Neuroprotective Agents - metabolism | Drug Carriers | Brain - metabolism | Nanoparticles | Parkinsonian Disorders - metabolism | Parkinsonian Disorders - drug therapy | Antiparkinson Agents - chemistry | Anti-Inflammatory Agents - administration & dosage | Female | Neurons - metabolism | Neuroprotective Agents - administration & dosage | Nanomedicine | Disease Models, Animal | Neuroprotective Agents - chemistry | Mice, Inbred C57BL | Solubility | Rats | Technology, Pharmaceutical - methods | Parkinsonian Disorders - chemically induced | Administration, Intranasal | Chemistry, Pharmaceutical | Brain - drug effects | Catalase - metabolism | Catalase - administration & dosage | Animals | Anti-Inflammatory Agents - chemistry | Antioxidants - administration & dosage | RAW 264.7 Cells | Antiparkinson Agents - administration & dosage | Mice | Kinetics | Oxidative Stress - drug effects | Antiparkinson Agents - metabolism | Catalase - chemistry | Drugs | Drug delivery systems | Proteases | Analysis | Antiparkinsonian agents | Vehicles
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2003, Volume 87, Issue 1, pp. 187 - 198
Journal Article
Vaccine, ISSN 0264-410X, 2012, Volume 30, Issue 29, pp. 4361 - 4368
Highlights ► Immunization of mice with gD plus IC31® elicits serum antibodies with HSV-2 neutralizing activity. ► Skin and nasomucosal immunization induce... 
Allergy and Immunology | Genital immunity | Immunization routes | Adjuvant | Mucosal vaccine | Type 1/type 2 immune responses | Herpes simplex virus | CPG OLIGODEOXYNUCLEOTIDES | MEDICINE, RESEARCH & EXPERIMENTAL | SIMPLEX-VIRUS TYPE-2 | BELLS-PALSY | GAMMA-INTERFERON | IMMUNOLOGY | MUCOSAL IMMUNE-RESPONSES | MOUSE VAGINA | INTRANASAL IMMUNIZATION | INFLUENZA VACCINE | T-LYMPHOCYTES | Oligodeoxyribonucleotides - administration & dosage | Adjuvants, Immunologic - administration & dosage | Spleen - immunology | Immunoglobulin G - blood | Mice, Inbred C57BL | Immunity, Mucosal | Vagina - immunology | Herpes Simplex Virus Vaccines - immunology | Administration, Intranasal | Antibodies, Viral - blood | Animals | Herpes Genitalis - prevention & control | Herpesvirus 2, Human - immunology | Injections, Subcutaneous | Interferon-gamma - immunology | Female | T-Lymphocytes - immunology | Viral Envelope Proteins - immunology | Mice | Oligopeptides - administration & dosage | Herpes Genitalis - immunology | Antibodies, Neutralizing - blood | Drug Combinations | Injections, Intradermal | Proteins | Studies | Sexually transmitted diseases--STD | Infections | Tuberculosis | Vaccines | Microbiology in the medical area | Mikrobiologi inom det medicinska området | Herpes simplex virus; Genital immunity; Adjuvant; Mucosal vaccine; Immunization routes; Type 1/type 2 immune responses
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 2007, Volume 337, Issue 1, pp. 1 - 24
Interest in intranasal (IN) administration as a non-invasive route for drug delivery continues to grow rapidly. The nasal mucosa offers numerous benefits as a... 
Intranasal drug delivery | Pharmacokinetics | Nasal mucosa | Physicochemical properties | IN-VIVO BIOAVAILABILITY | DEPENDENT DIABETIC-PATIENTS | DIMETHYL-BETA-CYCLODEXTRIN | DIFFERENT MOLECULAR-WEIGHTS | NORKETAMINE PLASMA-CONCENTRATIONS | intranasal drug delivery | physicochemical properties | pharmacokinetics | nasal mucosa | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | ACUTE CHILDHOOD SEIZURES | CSF FOLLOWING INTRANASAL | NASAL DRUG-DELIVERY | WATER-SOLUBLE COMPOUNDS | Cholinesterase Inhibitors - pharmacokinetics | Hypnotics and Sedatives - chemistry | Central Nervous System - metabolism | Molecular Weight | Humans | Vaccines - pharmacokinetics | Cholinesterase Inhibitors - chemistry | Hypnotics and Sedatives - administration & dosage | Antiemetics - administration & dosage | Analgesics - pharmacokinetics | Antiemetics - pharmacokinetics | Inflammation - metabolism | Vaccines - chemistry | Cardiovascular Agents - pharmacokinetics | Drug Compounding | Antiemetics - chemistry | Nasal Mucosa - metabolism | Cardiovascular Agents - administration & dosage | Drug Administration Schedule | Hypnotics and Sedatives - pharmacokinetics | Drug Stability | Solubility | Analgesics - administration & dosage | Administration, Intranasal | Chemistry, Pharmaceutical | Carrier Proteins - metabolism | Cholinesterase Inhibitors - administration & dosage | Analgesics - chemistry | Hydrophobic and Hydrophilic Interactions | Vaccines - administration & dosage | Cardiovascular Agents - chemistry
Journal Article