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Journal Article
The Journal of Physiology, ISSN 0022-3751, 10/2018, Volume 596, Issue 19, pp. 4753 - 4765
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2012, Volume 122, Issue 4, pp. 1339 - 1353
Defective brain insulin signaling has been suggested to contribute to the cognitive deficits in patients with Alzheimer's disease (AD). Although a connection... 
MAMMALIAN TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | INTRANASAL INSULIN | RECEPTOR-DEPENDENT MECHANISM | AMYLOID-BETA | AXONAL-TRANSPORT | TNF-ALPHA | SYNAPTIC PLASTICITY | CULTURED HIPPOCAMPAL-NEURONS | PEPTIDE OLIGOMERS | TRANSGENIC MICE | Phosphorylation | Insulin - physiology | Humans | Middle Aged | Macaca fascicularis | Memory Disorders - metabolism | Male | Hippocampus - drug effects | Insulin Receptor Substrate Proteins - metabolism | Infliximab | Alzheimer Disease - prevention & control | Aged, 80 and over | Female | Neurons - metabolism | Neurons - drug effects | Alzheimer Disease - psychology | Hypoglycemic Agents - therapeutic use | Cells, Cultured - drug effects | Amyloid beta-Peptides - toxicity | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Insulin Resistance | Rats | Mice, Transgenic | Hippocampus - pathology | Hippocampus - cytology | Maze Learning - drug effects | Hypoglycemic Agents - pharmacology | Peptides - pharmacology | Hippocampus - metabolism | Memory Disorders - prevention & control | Animals | MAP Kinase Signaling System - drug effects | Memory Disorders - etiology | Alzheimer Disease - metabolism | Venoms - therapeutic use | Aged | Cells, Cultured - metabolism | Mice | Protein Processing, Post-Translational | Venoms - pharmacology | Alzheimer Disease - genetics | Peptides - therapeutic use | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 09/2017, Volume 96, Issue 1, pp. 115 - 129.e5
Diabetes and impaired brain insulin signaling are linked to the pathogenesis of Alzheimer’s disease (AD). The association between diabetes and AD-associated... 
Aggregation | Endosomal dysfunction | Alzheimer’s disease | Trafficking | Aging | APOE | Insulin signaling | Alzheimer's disease | DIABETES-MELLITUS | SKELETAL-MUSCLE | INTRANASAL INSULIN | GLUCOSE-METABOLISM | IMPROVES COGNITION | ALZHEIMERS-DISEASE | A-BETA | AMYLOID PRECURSOR PROTEIN | APOE-GENOTYPE | MILD COGNITIVE IMPAIRMENT | NEUROSCIENCES | Apolipoprotein E4 - genetics | Apolipoprotein E4 - metabolism | Insulin - physiology | Male | Mice, Transgenic | Neurons - cytology | Endosomes - metabolism | Mice, Knockout | Glycolysis - physiology | Apolipoprotein E3 - genetics | Animals | Aging - physiology | Insulin Resistance - physiology | Diet, High-Fat | Cell Respiration - physiology | Neurons - physiology | Female | Receptor, Insulin - metabolism | Mice | Neurons - metabolism | Primary Cell Culture | Mitochondria - physiology | Aging - metabolism | Insulin resistance | Apolipoproteins | Neurons | Insulin | Medical research | Medical colleges | Nervous system diseases | Neurosciences | Medicine, Experimental | Risk factors | Brain | Pathogenesis | Clinical trials | Nervous system | Glucose | Kinases | High fat diet | Signal transduction | Mitochondria | Apolipoprotein E | Rodents | Shinto | Amyloid | Protein transport | Age | Apolipoprotein E4 | Neurodegenerative diseases | Diabetes mellitus | Metabolism | Studies | Musculoskeletal system | Trapping | Glycolysis | Diabetes | Electron transport | Endosomes | Dementia | Index Medicus
Journal Article
Journal Article
Journal Article