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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2014, Volume 111, Issue 29, pp. 10580 - 10585
Journal Article
06/2010
The divalent Ca2+ metal ion acts as a universal second messenger in virtually all eukaryotic cells from fungi to plants to mammals. In mammals, Ca2+ signaling... 
calcium | ion channel | 0760
Dissertation
Journal of Molecular Biology, ISSN 0022-2836, 2005, Volume 346, Issue 4, pp. 967 - 989
We present a refined model of the membrane-associated acetylcholine (ACh) receptor at 4 Å resolution. An improved experimental density map was obtained from... 
acetylcholine receptor | electron microscopy | refinement | ion channel | Refinement | Electron microscopy | Ion channel | Acetylcholine receptor
Journal Article
Annual Review of Neuroscience, ISSN 0147-006X, 07/2012, Volume 35, pp. 249 - 265
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2011, Volume 108, Issue 33, pp. 13823 - 13828
Journal Article
Developmental Biology, ISSN 0012-1606, 07/2019, Volume 451, Issue 1, pp. 68 - 78
Neurons, with their distinct neurites, require elaborate membrane trafficking pathways and regulation to uphold neurite identity and to be able to respond to... 
Pruning | Rab11 | Endocytosis | Ion channel | Dendrite
Journal Article
FEBS Letters, ISSN 0014-5793, 02/2007, Volume 581, Issue 3, pp. 483 - 488
The purinergic receptor P2X7 is part of a complex signaling mechanism participating in a variety of physiological and pathological processes. Depending on the... 
siRNA | Pannexin | P2X7 | Pore | Ion channel | P2X | ion channel | pore
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2011, Volume 108, Issue 32, pp. 13299 - 13304
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 08/2010, Volume 20, Issue 16, pp. 4951 - 4954
A series of analogues of the pyrazole lead 1 were synthesized in which the heterocyclic core was replaced with an imidazole. A number of potent antagonists... 
Ion channel | Pain | P2X
Journal Article
The EMBO Journal, ISSN 0261-4189, 11/2006, Volume 25, Issue 21, pp. 5071 - 5082
P2X7 receptors are ATP‐gated cation channels; their activation in macrophage also leads to rapid opening of a membrane pore permeable to dyes such as ethidium,... 
purine receptors | pro‐inflammatory cytokines | ion channel | hemichannel | inflammasome | Pro-inflammatory cytokines | Inflammasome | Hemichannel | Ion channel | Purine receptors | pro-inflammatory cytokines
Journal Article
Journal of General Virology, ISSN 0022-1317, 03/2017, Volume 98, Issue 3, pp. 345 - 351
Journal Article
Biochimica et Biophysica Acta - Biomembranes, ISSN 0005-2736, 07/2013, Volume 1828, Issue 7, pp. 1530 - 1540
The voltage-gated Ca channel β subunit (Ca β) is a cytosolic auxiliary subunit that plays an essential role in regulating the surface expression and gating... 
Auxiliary subunit | Synapse | Neuron | Ion channel | Calcium channel | Voltage-gated
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2017, Volume 114, Issue 34, pp. E7092 - E7100
Ion channels are proteins that span the cell’s membrane and affect the rapid transfer of ions. Kinases are proteins that transfer a phosphate from ATP to... 
PRMT5 | TRPM7 | Ion channel | Kinase | TRPM6 | Biological Sciences | kinase | PNAS Plus | ion channel
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 07/2009, Volume 385, Issue 3, pp. 472 - 477
We have recently shown that ATP-sensitive potassium (K ) channels in the heart are localized in the caveolae of cardiac myocytes and regulated by... 
Ion channel | Caveolin | Peptide
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2005, Volume 102, Issue 5, pp. 1408 - 1412
Journal Article
ACS Nano (online), ISSN 1936-0851, 2019, Volume 13, Issue 2
Ion channels form the basis of information processing in living cells by facilitating the exchange of electrical signals across and along cellular membranes.... 
biomimetic systems | ion channel | protein sequencing | gating | molecular dynamics
Journal Article
by Ge, JP and Li, WQ and Zhao, QC and Li, NN and Chen, MF and Zhi, P and Li, RC and Gao, N and Xiao, BL and Yang, MJ
NATURE, ISSN 0028-0836, 11/2015, Volume 527, Issue 7576, pp. 64 - 69
Piezo proteins are evolutionarily conserved and functionally diverse mechanosensitive cation channels. However, the overall structural architecture and gating... 
ACTIVATED ION-CHANNEL | MECHANISM | MERKEL CELLS | CRYSTAL-STRUCTURE | DISTAL ARTHROGRYPOSIS | MULTIDISCIPLINARY SCIENCES | STATE | OF-FUNCTION MUTATIONS | GATED SODIUM-CHANNEL | RECEPTORS | MECHANOTRANSDUCTION | Physiological aspects | Mammals | Ion channels
Journal Article
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