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PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, p. e54250
Type 2 diabetes mellitus (T2DM) describes a group of metabolic disorders characterized by defects in insulin secretion and insulin sensitivity. Insulin... 
PANCREATIC-ISLETS | ACID | 5-HT RECEPTORS | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | BETA-CELLS | IN-VIVO | DOPAMINE | MICE | TYPE-2 DIABETES-MELLITUS | EXPRESSION | Islets of Langerhans - drug effects | Palmitic Acid - pharmacology | Gene Expression - drug effects | Diabetes Mellitus, Type 2 - genetics | Humans | Receptor, Serotonin, 5-HT2C - metabolism | Male | Diabetes Mellitus, Type 2 - metabolism | Serotonin Receptor Agonists - pharmacology | Dose-Response Relationship, Drug | Insulin-Secreting Cells - metabolism | RNA Interference | Islets of Langerhans - metabolism | Indoles - pharmacology | Insulin Secretion | Mice, Inbred C57BL | Reverse Transcriptase Polymerase Chain Reaction | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Piperazines - pharmacology | Blotting, Western | Mice, Inbred ICR | Insulin - metabolism | Animals | Insulin-Secreting Cells - drug effects | Aminopyridines - pharmacology | Cell Line, Tumor | Mice | Receptor, Serotonin, 5-HT2C - genetics | Type 2 diabetes | Pancreatic beta cells | Serotonin | RNA | Phenols | Development and progression | Amino acids | Saturated fatty acids | Insulin | Reproductive health | Brain | Laboratories | Genomics | Homeostasis | Nervous system | Biosynthesis | Glucose | Palmitic acid | Defects | Etiology | Rodents | Inhibition | Pancreas | Dopamine | Secretion | Neurons | Therapeutic applications | RNA-mediated interference | Diabetes mellitus | Body temperature | Interference | Serotonin S2 receptors | Metabolism | Gene expression | Ribonucleic acid--RNA | Medicine | Studies | Signaling | Acids | Insulin resistance | Plasma levels | Diabetes | Metabolic disorders | Ribonucleic acid
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2009, Volume 297, Issue 1, pp. 58 - 72
Pancreatic β-cells possess an inherent ability to generate oscillatory signals that trigger insulin release. Coordination of the secretory activity among... 
PIP 2 | PIP 3 | Oscillations | PI3-kinase | Metabolism | cAMP | Insulin secretion | Ca 2 | Phospholipase C | PIP | CYCLIC ADENOSINE-MONOPHOSPHATE | GLUCOSE-INDUCED OSCILLATIONS | PROTEIN-KINASE-C | ISOLATED RAT ISLETS | SENSITIVE K+ CHANNELS | INTRACELLULAR CA2+ STORES | HIGH-VOLTAGE DISCHARGE | CELL BIOLOGY | GLUCAGON-LIKE PEPTIDE-1 | Ca2 | INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS | ENDOCRINOLOGY & METABOLISM | PIP3 | PANCREATIC BETA-CELLS | PIP2 | Phosphatidylinositol 4,5-Diphosphate - metabolism | Feedback, Physiological | Insulin - metabolism | Animals | Calcium - metabolism | Humans | Periodicity | Glucose - metabolism | Insulin Secretion | Type 2 diabetes | Phospholipases | Insulin | Diabetes therapy | Medical and Health Sciences | Medicin och hälsovetenskap | Cell biology | Klinisk medicin | MEDICINE | Morphology, cell biology, pathology | Medical Cell Biology | Endokrinologi och diabetes | Fysiologi och farmakologi | Diabetology | Physiology | Invärtesmedicin | Dermatologi och venerologi, klinisk genetik, invärtesmedicin | oscillations | Endocrinology and Diabetes | phospholipase C | Basic Medicine | Medicinsk cellbiologi | Internal medicine | Fysiologi | Cell and Molecular Biology | Diabetologi | Dermatology and venerology,clinical genetics, internal medicine | Clinical Medicine | Morfologi, cellbiologi, patologi | MEDICIN | Medicinska och farmaceutiska grundvetenskaper | metabolism | Cellbiologi | Cell- och molekylärbiologi | Physiology and pharmacology
Journal Article
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