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2011, Cambridge studies in biological and evolutionary anthropology, ISBN 9780521764339, Volume 60, xvii, 360
Long-tailed macaques (Macaca fascicularis) have a wide geographical distribution and extensively overlap with human societies across southeast Asia, regularly... 
Effect of human beings on | Ecology | Kra | Conservation
Book
11/2013
Colorectal cancer (CRC) is the third leading cause of death from cancer in North America. The KRAS gene is mutated in approximately 40-50% of all CRC, and this... 
0379 | c-MET | KRAS
Dissertation
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 05/2019, Volume 79, Issue 10, pp. 2462 - 2465
Cancer is one of the leading causes of death worldwide. This life-threatening disease requires novel strategies for the early detection and therapy response... 
ONCOLOGY | CANCER | KRAS
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 04/2019, Volume 62, Issue 8, pp. 4131 - 4141
Sirtuin 2 (SIRT2) is a protein lysine deacylase that has been indicated as a therapeutic target for cancer. To further establish the role of SIRT2 in cancers,... 
KRAS MUTATIONS | SPECIFICITY | CHEMISTRY, MEDICINAL
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 04/2019, Volume 561, pp. 114 - 123
KRAS is a small GTPase that regulates cell proliferation and survival. In tumors, the KRAS gene is mutated, and leading to unregulated tumor growth. Despite... 
Hyaluronan | siRNA | KRAS | CD44 | Polymer therapeutics | EFFICACY | ONCOGENIC KRAS | DOXORUBICIN | CHITOSAN NANOPARTICLES | HYALURONIC-ACID | MUTANT KRAS | THERAPY | K-RAS | PHARMACOLOGY & PHARMACY | INHIBITORS | EXPRESSION
Journal Article
MOLECULAR CANCER THERAPEUTICS, ISSN 1535-7163, 03/2019, Volume 18, Issue 3, pp. 613 - 620
Pancreatic ductal adenocarcinoma (PDAC) remains remarkably lethal with a 5-year survival rate of 8%. This is mainly attributed to the late stage of... 
KRAS | ONCOLOGY | ADENOCARCINOMA | IMMUNE EVASION
Journal Article
FUTURE MEDICINAL CHEMISTRY, ISSN 1756-8919, 05/2019, Volume 11, Issue 9, pp. 923 - 925
Journal Article
by Lin A and Hua RX and Tang J and Zhu J and Zhang R and Zhou H and Zhang J and Cheng J and Xia H and He J
OncoTargets and Therapy, ISSN 1178-6930, 09/2019, Volume 12, pp. 7289 - 7295
Ao Lin1,*, Rui-Xi Hua2,*, Jue Tang1,*, Jinhong Zhu3, Ruizhong Zhang1, Haixia Zhou4, Jiao Zhang5, Jiwen Cheng6, Huimin Xia1, Jing He1 1Department of Pediatric... 
susceptibility | neuroblastoma | KRAS | polymorphism
Journal Article
Journal Article
Journal of Maps, ISSN 1744-5647, 11/2016, Volume 12, Issue sup1, pp. 352 - 362
The paper aims to present the geology of the western part of the Classical Karst (NW Dinarides), located at the border between Slovenia and Italy. The work is... 
Kras-Carso | Italy | Classical Karst | Slovenia | Geology | Dinarides | Kras–Carso | ISTRIA | CROATIA | GEOGRAPHY, PHYSICAL | EVOLUTION | PALEOGEOGRAPHY | CARBONATE PLATFORM | KOMEN | KRAS | GEOGRAPHY
Journal Article
by Kubicka Prof, Stefan and Greil, R and André, T and Bennouna, J and Sastre, J and Van Cutsem, E and Von Moos, R and Österlund, P and Reyes-Rivera, I and Müller, T and Makrutzki, M and Arnold, D and Andel, J and Balcke, P and Benedicic, B and Eisterer, W and Fridrik, M and Jagdt, B and Keil, F and Kretschmer, A and Krippl, P and Oexle, H and Pecherstorfer, M and Samonigg, H and Schmid, M and Thaler, J and Tinchon, C and Weiss, H and Arts, J and De Man, M and Demolin, G and Janssens, J and Polus, M and Benczikova, B and Melichar, B and Prausova, J and Vitek, P and Andersen, F.Z and Jensen, B.B and Keldsen, N and Østerlind, K and Vistisen, K and Elme, A and Magi, A and Ojamaa, K and Ristamäki, R and Salminen, T and Ben Abdelghani, M and Bouche, O and Borg, C and Bouhier-Leporrier, K and Breysacher, G and Chone, L and Clavero Fabri, M.-C and Deplanque, G and Desseigne, F and Dourthe, L.-M and Ezenfis, J and Faroux, R and François, E and Garnier, C and Gaspard, M.-H and Hebbar, M and Illory, J.F and Kaminsky, M.-C and Lecomte, T and Legoux, J.-L and Levache, B and Lobry, C and Lotz, J.-P and Mabro, M and Manet-Lacombe, S and Manfredi, S and Matysiak Budnik, T and Miglianico, L and Mineur, L and Moullet, I and Naman, H and Nouyrigat, P and Oziel-Taieb, S and Perrier, H and Pezet, D and Philip, J and Pottier, V and Porneuf, M and Ramdani, M and Re, D and Rinaldi, Y and Spaeth, D and Taieb, J and Terrebonne, E and Texereau, P and Thirot Bidault, A and Tournigand, C and Tubiana-Mathieu, N and Vantelon, J.-M and Viret, F and Ychou, M and Bangerter, M and Bertram, M.E and ...
Annals of Oncology, ISSN 0923-7534, 09/2013, Volume 24, Issue 9, pp. 2342 - 2349
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2015, Volume 112, Issue 21, pp. 6625 - 6630
Journal Article
Nature, ISSN 0028-0836, 06/2012, Volume 486, Issue 7404, pp. 532 - 536
Journal Article
Cancer Research, ISSN 0008-5472, 2019, Volume 79, Issue 9, pp. 2352 - 2366
Combinatorial inhibition of MEK1/2 and CDK4/6 is currently undergoing clinical investigation in NRAS-mutant melanoma. To prospectively map the landscape of... 
DEPENDENCY | ONCOLOGY | SENSITIVITY | KRAS | SCALE | COMBINATION | CANCER
Journal Article
by Chen, H and Fan, K and Luo, GP and Fan, ZY and Yang, C and Huang, QY and Jin, KZ and Xu, J and Yu, XJ and Liu, C
CANCER LETTERS, ISSN 0304-3835, 2019, Volume 446, pp. 103 - 111
Genetic alterations have been attributed to the abnormal immune microenvironment in cancer. However, the relationship between the Kras(G12D) mutation and... 
Immunosuppressive | TGF-beta | PEPTIDES | ONCOLOGY | PROGNOSIS | SUBTYPES | Pancreatic cancer | ONCOGENIC KRAS | VACCINATION | Kras(G12D) mutation | IL-10
Journal Article
BRITISH JOURNAL OF CANCER, ISSN 0007-0920, 07/2019, Volume 121, Issue 3, pp. 197 - 198
Summary Despite its status as the most commonly mutated oncogene in cancer, Ras has long been considered ‘undruggable’. In 2019, we will see the first clinical... 
ONCOLOGY | CANCER | KRAS | Inhibitors | Index Medicus
Journal Article
BRITISH JOURNAL OF HAEMATOLOGY, ISSN 0007-1048, 08/2019, Volume 186, Issue 3, pp. E52 - E56
Journal Article