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humans (49) 49
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article (17) 17
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physiological aspects (12) 12
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binding (7) 7
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nocodazole - pharmacology (7) 7
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1. Full Text Checkpoint Inhibition of the APC/C in HeLa Cells Is Mediated by a Complex of BUBR1, BUB3, CDC20, and MAD2
by Valery Sudakin and Gordon K. T. Chan and Tim J. Yen
The Journal of Cell Biology, ISSN 0021-9525, 9/2001, Volume 154, Issue 5, pp. 925 - 936
The mitotic checkpoint prevents cells with unaligned chromosomes from prematurely exiting mitosis by inhibiting the anaphase-promoting complex/cyclosome... 
Gels | Mitosis | Interphase | Kinetochores | Ubiquitins | Cell cycle | HeLa cells | Antibodies | Chromosomes | Anaphase | MAD2 | Kinetochore | Anaphase promoting complex | Mitotic checkpoint | hBUBR1 | mitotic checkpoint | ANAPHASE-PROMOTING COMPLEX | BUDDING YEAST | UBIQUITIN LIGASE | PROTEIN-KINASE | CYCLIN-B | SPINDLE ASSEMBLY CHECKPOINT | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | kinetochore | anaphase promoting complex | CENP-E | UNATTACHED KINETOCHORES | Protein Kinases - metabolism | Anaphase-Promoting Complex-Cyclosome | Cell Fractionation | Ligases - isolation & purification | Humans | Protein-Serine-Threonine Kinases | Immunoblotting | Recombinant Fusion Proteins - metabolism | Ubiquitin-Protein Ligase Complexes | Poly-ADP-Ribose Binding Proteins | Genes, cdc - physiology | Mad2 Proteins | Cdc20 Proteins | Carrier Proteins | Calcium-Binding Proteins - metabolism | Kinetochores - metabolism | Cell Cycle Proteins - metabolism | Ligases - metabolism | Genes, Reporter - genetics | Macromolecular Substances | Nuclear Proteins | Ubiquitin-Protein Ligases | Proteins - metabolism | Ligases - antagonists & inhibitors | Mitosis - physiology | Saccharomyces cerevisiae Proteins | Recombinant Fusion Proteins - genetics | HeLa Cells | Fungal Proteins - metabolism | Physiological aspects | Chromosomal proteins | Research | kinetochore; hBUBR1; anaphase promoting complex; MAD2; mitotic checkpoint
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2. Full Text HBV X protein targets hBubR1, which induces dysregulation of the mitotic checkpoint
by Kim, S and Park, S.-Y and Yong, H and Famulski, J.K and Chae, S and Lee, J.-H and Kang, C.-M and Saya, H and Chan, G.K and Cho, H
Oncogene, ISSN 0950-9232, 05/2008, Volume 27, Issue 24, pp. 3457 - 3464
Accurate chromosomal segregation is monitored by the mitotic checkpoint, and an increased rate of chromosomal missegregation leads to chromosomal instability... 
Chromosome instability | HBV X | BubR1 | Mitotic checkpoint | CELLS | ONCOPROTEIN | MAD2 | mitotic checkpoint | ANAPHASE-PROMOTING COMPLEX | TUMOR-DEVELOPMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHROMOSOMAL INSTABILITY | CELL BIOLOGY | REGULATOR | INHIBITION | ONCOLOGY | CENTROSOME AMPLIFICATION | GENETICS & HEREDITY | chromosome instability | Anaphase-Promoting Complex-Cyclosome | Immunoprecipitation | Ubiquitin-Protein Ligase Complexes - physiology | Humans | Kinetochores | Spindle Apparatus | Transfection | Microtubules - drug effects | Carcinoma, Hepatocellular - genetics | Trans-Activators - genetics | Cdc20 Proteins | Chromosomal Instability | Protein-Serine-Threonine Kinases - metabolism | Chromosome Segregation | Liver Neoplasms - genetics | Chromosomes, Human - genetics | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Blotting, Western | Two-Hybrid System Techniques | Ubiquitin-Protein Ligase Complexes - metabolism | Mitosis - physiology | Fluorescent Antibody Technique | Liver Neoplasms - metabolism | Trans-Activators - metabolism | HeLa Cells | Saccharomyces cerevisiae | Carcinoma, Hepatocellular - metabolism | Proteins | Cell division | Oncology | Chromosomes | Binding sites | Index Medicus
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3. Full Text Breast cancer-specific gene 1 interacts with the mitotic checkpoint kinase BubR1
by Gupta, Anu and Inaba, Satoru and Wong, Oi Kwan and Fang, Guowei and Liu, Jingwen
Oncogene, ISSN 0950-9232, 10/2003, Volume 22, Issue 48, pp. 7593 - 7599
The abnormal expression of breast cancer-specific gene 1 (BCSG1) in malignant mammary epithelial cells is highly associated with the development and... 
Aneuploidy | Multinucleation | Yeast two-hybrid | BCSG1 | BubR1 | Mitotic checkpoint | HBUBR1 | CELLS | MAD2 | APOPTOSIS | mitotic checkpoint | ANAPHASE-PROMOTING COMPLEX | SYNUCLEIN-GAMMA | PHOSPHORYLATION | PROTEIN BUBR1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINETOCHORE LOCALIZATION | CELL BIOLOGY | multinucleation | ONCOLOGY | GENETICS & HEREDITY | aneuploidy | yeast two-hybrid | ABERRANT EXPRESSION | Protein Kinases - metabolism | Protein Kinases - genetics | Humans | Protein-Serine-Threonine Kinases | Nocodazole - pharmacology | gamma-Synuclein | Nerve Tissue Proteins | Neoplasm Proteins - metabolism | Two-Hybrid System Techniques | Mitosis - drug effects | Chromosome Aberrations - drug effects | Cell Line, Tumor | Protein Binding | Neoplasm Proteins - genetics | Cell Cycle Proteins | BCSG1 gene | BubR1 protein | nocodazole
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4. Full Text Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability
by Shin, Hyun-Jin and Baek, Kwan-Hyuck and Jeon, Ae-Hwa and Park, Moon-Taek and Lee, Hyun-Sook and Lee, Chang-Woo and Lee, Su-Jae and Kang, Chang-Mo and Yoo, Seong-Ho and Chung, Doo-Hyun and Sung, Young-Chul and McKeon, Frank
Cancer Cell, ISSN 1535-6108, 12/2003, Volume 4, Issue 6, pp. 483 - 497
In this study, we show that the formation of polyploidy following sustained mitotic checkpoint activation appears to be preceded by the ubiquitin-dependent... 
SISTER-CHROMATID COHESION | MAD2 | ANAPHASE-PROMOTING COMPLEX | HUMAN LUNG CANCERS | ONCOLOGY | PREMATURE ANAPHASE | CENP-E | SPINDLE ASSEMBLY CHECKPOINT | PROTEIN PHOSPHATASE 2A | MAMMALIAN-CELLS | KINETOCHORE LOCALIZATION | Immunohistochemistry | Protein Kinases - metabolism | Phosphorylation | Humans | Protein-Serine-Threonine Kinases | Nocodazole - pharmacology | Ubiquitin - metabolism | Colonic Neoplasms - metabolism | Spindle Apparatus | Colonic Neoplasms - physiopathology | Adenocarcinoma - metabolism | Caspases - metabolism | Adenocarcinoma - physiopathology | Cloning, Molecular | Protein Denaturation | Antineoplastic Agents - pharmacology | Polyploidy | Chromosomal Instability - genetics | Animals | Mitosis - physiology | Transplantation, Heterologous - pathology | Mice | Apoptosis - physiology | HeLa Cells | Cell Cycle Proteins
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5. Full Text Centromere-Associated Protein-E Is Essential for the Mammalian Mitotic Checkpoint to Prevent Aneuploidy Due to Single Chromosome Loss
by Beth A. A. Weaver and Zahid Q. Bonday and Frances R. Putkey and Geert J. P. L. Kops and Alain D. Silk and Don W. Cleveland
The Journal of Cell Biology, ISSN 0021-9525, 8/2003, Volume 162, Issue 4, pp. 551 - 563
Centromere-associated protein-E (CENP-E) is an essential mitotic kinesin that is required for efficient, stable microtubule capture at kinetochores. It also... 
Hepatocytes | Kinetochores | Metaphase | Microtubules | HeLa cells | Aneuploidy | Mice | Chromosomes | Anaphase | Cells | LENP-E | Kinetochore | Mitosis | BubR1 | Cell cycle | MAD2 | SPINDLE MICROTUBULES | cell cycle | mitosis | KINETOCHORE LOCALIZATION | CELL BIOLOGY | ANAPHASE ONSET | kinetochore | MICROTUBULE ATTACHMENT | CENP-E | CYCLOSOME/ANAPHASE-PROMOTING COMPLEX | INTERFERING RNAS | LIVING CELLS | Protein Kinases - metabolism | Chromosomal Proteins, Non-Histone - metabolism | Kinetochores - metabolism | Humans | Protein-Serine-Threonine Kinases | Centromere - metabolism | Sequence Analysis, DNA | Viral Proteins - metabolism | Animals | Mitosis - physiology | Fibroblasts | Integrases - metabolism | HeLa Cells | Cell Cycle Proteins | Physiological aspects | Research | Kinesin | Cytology | kinetochore; mitosis; cell cycle; LENP-E; BubR1
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6. Full Text MAD3 Encodes a Novel Component of the Spindle Checkpoint Which Interacts with Bub3p, Cdc20p, and Mad2p
by Kevin G. Hardwick and Raymond C. Johnston and Dana L. Smith and Andrew W. Murray
The Journal of Cell Biology, ISSN 0021-9525, 3/2000, Volume 148, Issue 5, pp. 871 - 882
We show that MAD3 encodes a novel 58-kD nuclear protein which is not essential for viability, but is an integral component of the spindle checkpoint in budding... 
Yeasts | Kinetochores | Cell cycle | Antibodies | Amino acids | Anaphase | Genetic mutation | Saccharomycetales | Cells | Mitotic spindle apparatus | CDC20 | MAD3 | MAD2 | Checkpoint | BUB3 | checkpoint | SISTER-CHROMATID COHESION | CYCLIN PROTEOLYSIS | BUDDING YEAST | ESCHERICHIA-COLI | ANAPHASE INITIATION | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | ASSEMBLY CHECKPOINT | CYCLOSOME/ANAPHASE-PROMOTING COMPLEX | MITOTIC CHECKPOINT | UNATTACHED KINETOCHORES | Protein Kinases - genetics | Protein-Serine-Threonine Kinases | Molecular Sequence Data | Cell Cycle Proteins - immunology | Fungal Proteins - immunology | Spindle Apparatus - genetics | Cloning, Molecular | Cell Cycle Proteins - genetics | Mad2 Proteins | Cdc20 Proteins | Saccharomycetales - cytology | Carrier Proteins | Calcium-Binding Proteins - metabolism | Mutagenesis, Site-Directed | Cell Cycle Proteins - metabolism | Protein Structure, Tertiary - genetics | Fungal Proteins - genetics | Saccharomycetales - enzymology | Precipitin Tests | Nuclear Proteins | Sequence Homology, Amino Acid | Saccharomycetales - genetics | Two-Hybrid System Techniques | Proteins - metabolism | Saccharomyces cerevisiae Proteins | Genes, cdc | Fungal Proteins - metabolism | Spindle (Cell division) | Mitosis | Research | MAD3 gene | Bub3 protein | Mad2 protein | Cdc20 protein | Mad3 protein | Original
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7. Full Text The Spindle Assembly Checkpoint Is Not Essential for CSF Arrest of Mouse Oocytes
by Chizuko Tsurumi and Steffen Hoffmann and Stephan Geley and Ralph Graeser and Zbigniew Polanski
The Journal of Cell Biology, ISSN 0021-9525, 12/2004, Volume 167, Issue 6, pp. 1037 - 1050
In Xenopus oocytes, the spindle assembly checkpoint (SAC) kinase Bub1 is required for cytostatic factor (CSF)-induced metaphase arrest in meiosis II. To... 
Strontium | Metaphase | Kinetochores | Meiosis | Chromosomes | Anaphase | Oocytes | Eggs | Cyclins | Mitotic spindle apparatus | PROTO-ONCOGENE PRODUCT | MATURATION-PROMOTING FACTOR | VERTEBRATE EGGS | XENOPUS-OOCYTES | CENP-E | MEIOTIC MATURATION | CYTOSTATIC FACTOR | MITOTIC CHECKPOINT | SACCHAROMYCES-CEREVISIAE | KINETOCHORE LOCALIZATION | CELL BIOLOGY | Protein Kinases - metabolism | Anaphase-Promoting Complex-Cyclosome | Oocytes - metabolism | Spindle Apparatus - chemistry | Ubiquitin-Protein Ligase Complexes - physiology | Protein-Serine-Threonine Kinases | Ubiquitin-Protein Ligase Complexes - antagonists & inhibitors | Nocodazole - pharmacology | Proto-Oncogene Proteins c-mos - physiology | Mice, Inbred Strains | Nuclear Proteins | Oocytes - cytology | Animals | Carrier Proteins - metabolism | Strontium - pharmacology | Spindle Apparatus - genetics | Female | Proto-Oncogene Proteins c-mos - metabolism | Mad2 Proteins | Mice | Mutation | Spindle Apparatus - physiology | Cell Cycle Proteins
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8. Full Text Molecular analyses of the mitotic checkpoint components hsMAD2, hBUB1 and hBUB3 in human cancer
by Hernando, Eva and Orlow, Irene and Liberal, Vasco and Nohales, Gloria and Benezra, Robert and Cordon‐Cardo, Carlos
International Journal of Cancer, ISSN 0020-7136, 07/2001, Volume 95, Issue 4, pp. 223 - 227
During the metaphase–anaphase transition, the spindle checkpoint prevents segregation of chromosomes if the spindle assembly is perturbed. Critical components... 
kinetochore | mitotic checkpoint | hBUB1 | hBUB3 | cell cycle | hsMAD2 | Kinetochore | Mitotic checkpoint | Cell cycle | PROTEIN MAD2 | ANAPHASE INITIATION | IDENTIFICATION | SACCHAROMYCES-CEREVISIAE | MITOSIS | LUNG-CANCER | ONCOLOGY | GENES | CELL-CYCLE | CYCLOSOME/ANAPHASE-PROMOTING COMPLEX | HUMAN BLADDER-TUMORS | Calcium-Binding Proteins - metabolism | Protein Kinases - metabolism | Protein Kinases - genetics | Liver Neoplasms - genetics | Humans | Protein-Serine-Threonine Kinases | Repressor Proteins | Cell Cycle Proteins - metabolism | Polymorphism, Genetic | Proteins - genetics | Poly-ADP-Ribose Binding Proteins | Proteins - metabolism | Urinary Bladder Neoplasms - genetics | DNA Mutational Analysis | Carcinoma, Hepatocellular - genetics | Gene Deletion | Cell Cycle Proteins - genetics | Mad2 Proteins | DNA, Neoplasm - genetics | Mutation | Sarcoma - genetics | Tumor Cells, Cultured | Soft Tissue Neoplasms - genetics | Calcium-Binding Proteins - genetics
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9. Full Text BubR1 Is Essential for Kinetochore Localization of Other Spindle Checkpoint Proteins and Its Phosphorylation Requires Mad1
by Rey-Huei Chen
The Journal of Cell Biology, ISSN 0021-9525, 8/2002, Volume 158, Issue 3, pp. 487 - 496
The spindle checkpoint delays anaphase onset until all chromosomes have attached properly to the mitotic spindle. Checkpoint signal is generated at... 
Phosphorylation | Phosphatases | Interphase | Kinetochores | Metaphase | Antibodies | Ova | Chromosomes | Eggs | Mitotic spindle apparatus | Xenopus | Spindle checkpoint | Mad1 | Bub1 | BubR1 | ANAPHASE-PROMOTING COMPLEX | BUDDING YEAST | KINASE | CELL BIOLOGY | CDC20 | ASSEMBLY CHECKPOINT | GENE | COMPONENT | MUTATIONS | MITOTIC CHECKPOINT | spindle checkpoint | UNATTACHED KINETOCHORES | Protein Binding - genetics | Protein Kinases - genetics | Molecular Weight | Xenopus Proteins - genetics | Protein-Serine-Threonine Kinases | Eukaryotic Cells - metabolism | Phosphoproteins - metabolism | Oocytes | Spindle Apparatus - metabolism | Cell Cycle Proteins - genetics | Protein Kinases - isolation & purification | Female | Genes, cdc - physiology | Mad2 Proteins | Cdc20 Proteins | Spindle Apparatus - ultrastructure | Repressor Proteins - metabolism | Carrier Proteins | Xenopus Proteins - isolation & purification | Calcium-Binding Proteins - metabolism | Chromosomal Proteins, Non-Histone - metabolism | Kinetochores - metabolism | Xenopus laevis | Cell Cycle Proteins - metabolism | Cells, Cultured | Repressor Proteins - genetics | Fungal Proteins - genetics | Phosphoproteins - genetics | Sequence Homology, Nucleic Acid | Chromosomal Proteins, Non-Histone - genetics | Nuclear Proteins | Sequence Homology, Amino Acid | Kinetochores - ultrastructure | Animals | Saccharomyces cerevisiae Proteins | Eukaryotic Cells - cytology | Calcium-Binding Proteins - genetics | Fungal Proteins - metabolism | Cell research | Carrier proteins | Analysis | Microtubules | Physiological aspects | Genetic aspects | Protein kinases | spindle checkpoint; Xenopus; BubR1; Mad1; Bub1
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10. Full Text hBub1 deficiency triggers a novel p53 mediated early apoptotic checkpoint pathway in mitotic spindle damaged cells
by Gao, Fangming and Ponte, Jose F and Levy, Mary and Papageorgis, Panagiotis and Ozturk, Sait and Lambert, Arthur W and Pan, Hongjie and Chinnappan, Dharmaraj and Cheng, Kuang-hung and Thiagalingam, Arunthathi and Abdolmaleky, Hamid Mostafavi and Thiagalingam, Sam
Cancer Biology & Therapy, ISSN 1538-4047, 04/2009, Volume 8, Issue 7, pp. 627 - 635
It has been universally believed that spindle assembly checkpoint (SAC) proteins which include the kinetochore proteins are involved in monitoring the faithful... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | hBub1 | hMad2 | shRNA | Spindle assembly checkpoint | Aneuploidy | PUMA | Apoptosis | Genomic instability | p53 | PROTEIN MAD2 | spindle assembly checkpoint | KINASE | apoptosis | KINETOCHORE LOCALIZATION | ASSEMBLY CHECKPOINT | GENE | ONCOLOGY | CHROMOSOME MISSEGREGATION | aneuploidy | CENP-E | cancer | HUMAN CANCERS | genomic instability | CYCLOSOME/ANAPHASE-PROMOTING COMPLEX | BUB1 | Protein-Serine-Threonine Kinases - deficiency | RNA, Small Interfering - genetics | Up-Regulation | Humans | bcl-2-Associated X Protein - biosynthesis | Cell Growth Processes - physiology | Proto-Oncogene Proteins - biosynthesis | Tumor Suppressor Protein p53 - genetics | Spindle Apparatus - metabolism | Spindle Apparatus - genetics | Apoptosis Regulatory Proteins - genetics | Cell Cycle Proteins - genetics | Mad2 Proteins | Protein-Serine-Threonine Kinases - metabolism | bcl-2-Associated X Protein - genetics | Apoptosis Regulatory Proteins - biosynthesis | Calcium-Binding Proteins - biosynthesis | HCT116 Cells | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | Repressor Proteins - genetics | Proto-Oncogene Proteins - genetics | Cell Cycle Proteins - biosynthesis | Tumor Suppressor Protein p53 - deficiency | Repressor Proteins - biosynthesis | Apoptosis - physiology | Calcium-Binding Proteins - genetics
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11. Full Text The spindle checkpoint: a quality control mechanism which ensures accurate chromosome segregation
by Taylor, Stephen S and Scott, Maria I. F and Holland, Andrew J
Chromosome Research, ISSN 0967-3849, 9/2004, Volume 12, Issue 6, pp. 599 - 616
The centromere defines where on a chromosome the kinetochores assemble. Kinetochores, large protein structures, mediate chromosome segregation during mitosis... 
Human Genetics | checkpoint | microtubule | Biomedicine | meiosis | kinetochore | mitosis | Plant Genetics & Genomics | Animal Genetics and Genomics | Checkpoint | Meiosis | Kinetochore | Microtubule | Mitosis | ANAPHASE-PROMOTING COMPLEX | BUDDING YEAST | BIOCHEMISTRY & MOLECULAR BIOLOGY | RNA EXPORT FACTOR | SACCHAROMYCES-CEREVISIAE | KINETOCHORE LOCALIZATION | ASSEMBLY CHECKPOINT | GENETICS & HEREDITY | CENP-E | POLYPOSIS-COLI PROTEIN | CELL-CYCLE | MITOTIC CHECKPOINT | Calcium-Binding Proteins - metabolism | Protein Kinases - metabolism | Amino Acid Sequence | Chromosome Segregation | Kinetochores - metabolism | Humans | Protein-Serine-Threonine Kinases | Repressor Proteins | Molecular Sequence Data | Animals | Spindle Apparatus - metabolism | Neoplasms - genetics | Protein Kinases - physiology | Mad2 Proteins | Spindle Apparatus - physiology | Cell Cycle Proteins | Cell division | Chromosomes | Cell cycle
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12. Full Text A New View of the Spindle Checkpoint
by M. Andrew Hoyt
The Journal of Cell Biology, ISSN 0021-9525, 9/2001, Volume 154, Issue 5, pp. 909 - 911
Previous studies of the spindle checkpoint suggested that its ability to prevent entry into anaphase was mediated by the inhibition of the anaphase-promoting... 
Yeasts | Comment | Mitosis | Kinetochores | Microtubules | Ubiquitins | Cell cycle | Gene expression regulation | Anaphase | Chromosomes | Cell cycle proteins | TARGET | CDC20 | MAD2 | CELLS | ANAPHASE-PROMOTING COMPLEX | KINETOCHORES | KINASE | BUBR1 | CENP-E | MITOTIC CHECKPOINT | CELL BIOLOGY | Calcium-Binding Proteins - metabolism | Protein Kinases - metabolism | Anaphase-Promoting Complex-Cyclosome | Chromosomal Proteins, Non-Histone - metabolism | Kinetochores - metabolism | Protein-Serine-Threonine Kinases | Cell Cycle Proteins - metabolism | Ligases - metabolism | Nuclear Proteins | Ubiquitin-Protein Ligase Complexes | Cell Division - physiology | Ubiquitin-Protein Ligases | Yeasts - physiology | Animals | Ligases - antagonists & inhibitors | Molecular Motor Proteins - metabolism | Signal Transduction - physiology | Spindle Apparatus - physiology | Carrier Proteins | Fungal Proteins - metabolism | Spindle (Cell division) | Cell division | Physiological aspects | Cell research
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13. Full Text Phosphorylation and activation of Bub1 on unattached chromosomes facilitate the spindle checkpoint
by Chen, Rey-Huei
The EMBO Journal, ISSN 0261-4189, 08/2004, Volume 23, Issue 15, pp. 3113 - 3121
The spindle checkpoint inhibits anaphase until all kinetochores have attached properly to spindle microtubules. The protein kinase Bub1 is an essential... 
kinetochore | MAP kinase | Bub1 | phosphorylation | spindle checkpoint | Phosphorylation | Spindle checkpoint | Kinetochore | MAD2 | ANAPHASE-PROMOTING COMPLEX | BUDDING YEAST | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINETOCHORE LOCALIZATION | CELL BIOLOGY | MITOSIS | ASSEMBLY CHECKPOINT | CENP-E | MITOTIC CHECKPOINT | Protein Kinases - metabolism | Protein Kinases - genetics | Kinetochores - metabolism | Protein-Serine-Threonine Kinases | Xenopus laevis | Extracellular Signal-Regulated MAP Kinases - metabolism | Mutation - genetics | Ovum - cytology | Animals | Spindle Apparatus - metabolism | Cell Cycle | Chromosomes - metabolism | Enzyme Activation | Cell Cycle Proteins | Ovum - metabolism
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14. Full Text The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments
by Logarinho, Elsa and Resende, Tatiana and Torres, Cláudia and Bousbaa, Hassan
Molecular Biology of the Cell, ISSN 1059-1524, 04/2008, Volume 19, Issue 4, pp. 1798 - 1813
The spindle assembly checkpoint monitors the status of kinetochore-microtubule (K-MT) attachments and delays anaphase onset until full metaphase alignment is... 
MAD2 | LOCALIZATION | ANAPHASE | COMPLEX | INHIBITION | CENP-E | TENSION | MITOTIC CHECKPOINT | CHROMOSOME MOTION | AURORA-B | CELL BIOLOGY | RNA, Small Interfering - genetics | Chromosomal Proteins, Non-Histone - metabolism | Kinetochores - metabolism | Humans | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Cell Cycle Proteins - antagonists & inhibitors | Poly-ADP-Ribose Binding Proteins | Kinetochores - ultrastructure | Microtubules - metabolism | Spindle Apparatus - metabolism | Cell Cycle | RNA Interference | Base Sequence | Microtubules - ultrastructure | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | HeLa Cells | Chromosome Pairing | Protein-Serine-Threonine Kinases - metabolism
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15. Full Text CAMP (C13orf8, ZNF828) is a novel regulator of kinetochore-microtubule attachment
by Chiba, Shuhei and Watanabe, Kana and Yasui, Akira and Tanaka, Kozo and Uchida, Kazuhiko S K and Kanno, Shin-ichiro and Itoh, Go and Hirota, Toru and Sugino, Shiro and Mizuno, Kensaku
The EMBO Journal, ISSN 0261-4189, 01/2011, Volume 30, Issue 1, pp. 130 - 144
Proper attachment of microtubules to kinetochores is essential for accurate chromosome segregation. Here, we report a novel protein involved in... 
microtubule | kinetochore | metaphase | spindle | chromosome | SPINDLE CHECKPOINT | ANAPHASE-PROMOTING COMPLEX | PROTEIN | FIBERS CONTRIBUTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHROMOSOME ALIGNMENT | MAMMALIAN-CELLS | CELL BIOLOGY | MITOSIS | MITOTIC SPINDLE | CENP-E | SKA COMPLEX | Chromosomal Proteins, Non-Histone - metabolism | Kinetochores - metabolism | Mitosis | Humans | Phosphoproteins - genetics | Phosphoproteins - metabolism | Chromosomal Proteins, Non-Histone - genetics | Kinetochores - ultrastructure | Microtubules - metabolism | Proteins - metabolism | Phosphoproteins - analysis | RNA Interference | Chromosomal Proteins, Non-Histone - analysis | Microtubules - ultrastructure | Chromosomes, Human | Mad2 Proteins | HeLa Cells | Spindle Apparatus - ultrastructure | Proteins | Cell division | Molecular biology | Chromosomes | Research methodology
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