Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (4596) 4596
Book Chapter (85) 85
Dissertation (51) 51
Publication (8) 8
Book / eBook (5) 5
Conference Proceeding (4) 4
Journal / eJournal (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (2635) 2635
life sciences & biomedicine (2488) 2488
humans (2133) 2133
animals (1947) 1947
kynurenine (1559) 1559
tryptophan (1475) 1475
male (1450) 1450
kynurenine - metabolism (1424) 1424
tryptophan - metabolism (1238) 1238
female (1112) 1112
rats (748) 748
neurosciences & neurology (742) 742
neurosciences (717) 717
biological and medical sciences (669) 669
adult (608) 608
biochemistry & molecular biology (602) 602
middle aged (551) 551
kynurenine - blood (539) 539
metabolites (521) 521
kynurenic acid (517) 517
mice (517) 517
kynurenine - analogs & derivatives (489) 489
kynurenine pathway (481) 481
medical sciences (424) 424
inflammation (413) 413
tryptophan - blood (413) 413
immunology (371) 371
pharmacology & pharmacy (366) 366
enzymes (365) 365
aged (350) 350
indoleamine-pyrrole 2,3,-dioxygenase - metabolism (341) 341
quinolinic acid (339) 339
physiological aspects (336) 336
analysis (331) 331
kynurenine - urine (321) 321
kynurenine - pharmacology (316) 316
psychiatry (314) 314
fundamental and applied biological sciences. psychology (307) 307
brain - metabolism (280) 280
metabolism (280) 280
chemistry (263) 263
kynurenic acid - metabolism (263) 263
tryptophan oxygenase - metabolism (263) 263
indoleamine 2,3-dioxygenase (260) 260
research (243) 243
liver - enzymology (235) 235
neurology (234) 234
depression (227) 227
kinetics (219) 219
serotonin (219) 219
chromatography, high pressure liquid (212) 212
cell biology (210) 210
physical sciences (210) 210
kynurenines (204) 204
clinical neurology (196) 196
health aspects (192) 192
schizophrenia (192) 192
amino acids (187) 187
time factors (185) 185
transaminases - metabolism (184) 184
kynurenine 3-monooxygenase (181) 181
cytokines (179) 179
abridged index medicus (178) 178
mass spectrometry (168) 168
brain (167) 167
xanthurenates - urine (166) 166
cells, cultured (165) 165
disease models, animal (164) 164
kynurenine - chemistry (164) 164
old medline (164) 164
adolescent (162) 162
kynurenine - analysis (162) 162
neopterin (160) 160
enzyme inhibitors - pharmacology (157) 157
mice, inbred c57bl (157) 157
in vitro techniques (152) 152
rats, sprague-dawley (152) 152
tryptophan - pharmacology (151) 151
serotonin - metabolism (150) 150
biomarkers - blood (148) 148
proteins (147) 147
quinolinic acid - metabolism (143) 143
rats, wistar (143) 143
tryptophan metabolism (142) 142
gene expression (141) 141
oxidation-reduction (138) 138
child (136) 136
neuroprotection (133) 133
oxidative stress (133) 133
young adult (132) 132
indoleamine-pyrrole 2,3,-dioxygenase - genetics (131) 131
physiology (130) 130
hydrolases - metabolism (129) 129
research article (129) 129
case-control studies (127) 127
pharmacology. drug treatments (127) 127
depression, mental (126) 126
ido (126) 126
kynurenine - biosynthesis (126) 126
oncology (126) 126
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (4443) 4443
German (92) 92
Japanese (91) 91
Russian (90) 90
Italian (40) 40
French (36) 36
Chinese (15) 15
Polish (14) 14
Portuguese (9) 9
Hungarian (6) 6
Spanish (4) 4
Czech (3) 3
Norwegian (1) 1
Persian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Targeted deletion of kynurenine 3-Monooxygenase in mice a new tool for studying kynurenine pathway metabolism in periphery and brain
by Giorgini, Flaviano and Huang, Shao-Yi and Sathyasaikumar, Korrapati V and Notarangelo, Francesca M and Thomas, Marian A. R and Tararina, Margarita and Wu, Hui-Qiu and Schwarcz, Robert and Muchowski, Paul J
The Journal of biological chemistry, ISSN 0021-9258, 12/2013, Volume 288, Issue 51, pp. 36554 - 36566
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Kynurenine 3-Monooxygenase - genetics | Liver - metabolism | Kynurenine 3-Monooxygenase - metabolism | Gene Knockout Techniques | Organ Specificity | Kynurenine - analogs & derivatives | Tryptophan - metabolism | Mice, Knockout | Brain - metabolism | Kynurenine - blood | Animals | Gene Deletion | Mice | Kynurenine - metabolism | Index Medicus | Neuroprotection | Neurodegeneration | Kynurenic Acid | Schizophrenia | Tryptophan | Kynurenine | Kynurenine 3-Monooxygenase | Metabolism
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Interleukin-1 beta: A New Regulator of the Kynurenine Pathway Affecting Human Hippocampal Neurogenesis
by Zunszain, Patricia A and Anacker, Christoph and Cattaneo, Annamaria and Choudhury, Shanas and Musaelyan, Ksenia and Myint, Aye-Mu and Thuret, Sanine and Price, Jack and Pariante, Carmine M
Neuropsychopharmacology (New York, N.Y.), ISSN 0893-133X, 03/2012, Volume 37, Issue 4, pp. 939 - 949
kynurenine 3-monooxygenase (KMO) inhibitor | indolamine-2,3-dioxygenase (IDO) | inflammation | hippocampal stem cells | pro-inflammatory cytokines | indolamine-2,3- dioxygenase (IDO) | Pharmacology & Pharmacy | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Cell Line | Inflammation - pathology | Interleukin-1beta - pharmacology | Interleukin-1beta - physiology | Humans | Kynurenine - biosynthesis | Multipotent Stem Cells - metabolism | Hippocampus - cytology | Hippocampus - metabolism | Neural Inhibition - physiology | Inflammation - metabolism | Signal Transduction - drug effects | Cell Differentiation - drug effects | Multipotent Stem Cells - cytology | Neurogenesis - physiology | Kynurenine - toxicity | Signal Transduction - physiology | Neurogenesis - drug effects | Hippocampus - physiology | Cell Differentiation - physiology | Enzymes | Neurotoxicity | Metabolites | Neuroblasts | Interleukin 1 | Stem cells | Kynurenine 3-monooxygenase | Tryptophan | Depression | Inflammation | Neurogenesis | Hippocampus | Index Medicus | neurogenetics | neurodegeneration | kynurenine | unipolar | molecular & cellular neurobiology | neuroprotection | neurogenesis | bipolar | depression | pro-inflammatory cytokine | Original
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Major developments in the design of inhibitors along the kynurenine pathway
by Jacobs, Kelly R and Castellano-González, Gloria and Guillemin, Gilles J and Lovejoy, David B
Current medicinal chemistry, ISSN 0929-8673, 2017, Volume 24, Issue 23, pp. 2471 - 2495
Kynurenine Pathway | Kynurenine 3-monooxygenase | Indoleamine 2,3-dioxygenase | Enzyme inhibitors | Neurodegeneration | Cancer | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Enzyme Inhibitors - metabolism | Kynurenine 3-Monooxygenase - antagonists & inhibitors | Enzyme Inhibitors - chemistry | Humans | Drug Design | Enzyme Inhibitors - pharmacology | Transaminases - metabolism | Transaminases - antagonists & inhibitors | Kynurenine 3-Monooxygenase - metabolism | Kynurenine - metabolism | Indoleamine-Pyrrole 2,3,-Dioxygenase - antagonists & inhibitors | Enzymes | Enzyme activity | Mental disorders | Tryptophan 2,3-dioxygenase | Metabolism | Monooxygenase | Kynurenine-oxoglutarate transaminase | Inhibitors | Molecular modelling | Enzymatic activity | Crystal structure
Journal Article
Details down arrow
4. Full Text An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
by Opitz, Christiane A and Litzenburger, Ulrike M and Sahm, Felix and Ott, Martina and Tritschler, Isabel and Trump, Saskia and Schumacher, Theresa and Jestaedt, Leonie and Schrenk, Dieter and Weller, Michael and Jugold, Manfred and Guillemin, Gilles J and Miller, Christine L and Lutz, Christian and Radlwimmer, Bernhard and Lehmann, Irina and Von Deimling, Andreas and Wick, Wolfgang and Platten, Michael
Nature (London), ISSN 0028-0836, 10/2011, Volume 478, Issue 7368, pp. 197 - 203
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neurology | Biological and medical sciences | Medical sciences | Tumors of the nervous system. Phacomatoses | Neoplasm Transplantation | Humans | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Tryptophan - metabolism | Brain Neoplasms - metabolism | Glioma - metabolism | Glioma - genetics | Brain Neoplasms - immunology | Glioma - pathology | Receptors, Aryl Hydrocarbon - metabolism | Kynurenine - metabolism | Autocrine Communication | Paracrine Communication | Cell Survival | Kynurenine - pharmacology | Mice, Inbred C57BL | Brain Neoplasms - genetics | Glioma - immunology | Disease Progression | Tryptophan Oxygenase - metabolism | Tryptophan Oxygenase - genetics | Animals | Mice, Nude | Kynurenine - secretion | Cell Line, Tumor | Ligands | Mice | Tryptophan Oxygenase - deficiency | Kynurenine - immunology | Receptors, Aryl Hydrocarbon - immunology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences
by Fujigaki, Hidetsugu and Yamamoto, Yasuko and Saito, Kuniaki
Neuropharmacology, ISSN 0028-3908, 01/2017, Volume 112, Issue Pt B, pp. 264 - 274
Kynurenine aminotransferase | Kynurenine 3-monooxygenase | Kynurenine | Indoleamine 2,3-dioxygenase | Kynurenic acid | Quinolinic acid | Kynurenine pathway | Pharmacology & Pharmacy | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Nervous System Diseases - enzymology | Animals | Humans | Metabolic Networks and Pathways - physiology | Kynurenine - metabolism | Metabolic Networks and Pathways - drug effects | Tryptophan - metabolism | Nervous System Diseases - pathology | Nervous System Diseases - therapy | Methyl aspartate | Enzymes | Medical colleges | Nervous system diseases | Metabolites | Physiological aspects | Tryptophan | Inflammation | Health aspects | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster
by Han, Qian and Robinson, Howard and Li, Jianyong and Brookhaven National Laboratory (BNL)
Biochemical journal, ISSN 0264-6021, 09/2012, Volume 446, Issue 2, pp. 253 - 260
Kynurenine formamidase (KFase) | N-formyl-L-kynurenine (NFK) | PMSF | Tryptophan metabolism | Diazinon | α/β hydrolase | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Insecticides - chemistry | Arylformamidase - antagonists & inhibitors | Arylformamidase - metabolism | Crystallography, X-Ray | Drosophila Proteins - metabolism | Tosyl Compounds - pharmacology | Drosophila melanogaster - metabolism | Computer Simulation | Enzyme Inhibitors - chemistry | Kynurenine - metabolism | Drosophila Proteins - antagonists & inhibitors | Insecticides - pharmacology | Recombinant Proteins - metabolism | Catalytic Domain | Recombinant Proteins - antagonists & inhibitors | Biocatalysis | Enzyme Inhibitors - metabolism | Enzyme Inhibitors - pharmacology | Models, Molecular | Recombinant Proteins - chemistry | Kynurenine - chemistry | Tosyl Compounds - chemistry | Drosophila Proteins - chemistry | Kynurenine - analogs & derivatives | Arylformamidase - genetics | Animals | Insecticides - metabolism | Arylformamidase - chemistry | Tosyl Compounds - metabolism | Drosophila melanogaster - enzymology | Hydrophobic and Hydrophilic Interactions | Protein Binding | Ligands | Protein Conformation | Drosophila Proteins - genetics | Kinetics | Index Medicus | Kynurenine formamidase | kynurenine | N-formyl-L-kynurenine | phenylmethylsulfonyl fluoride | tryptophan metabolism | alpha/beta hydrolase | diazinon | kynurenine formamidase (KFase) | β hydrolase
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text The Kynurenine Pathway Modulates Neurodegeneration in a Drosophila Model of Huntington's Disease
by Campesan, Susanna and Green, Edward W and Breda, Carlo and Sathyasaikumar, Korrapati V and Muchowski, Paul J and Schwarcz, Robert and Kyriacou, Charalambos P and Giorgini, Flaviano
Current biology, ISSN 0960-9822, 2011, Volume 21, Issue 11, pp. 961 - 966
Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Tryptophan Oxygenase - antagonists & inhibitors | Neuroprotective Agents - chemistry | Kynurenine 3-Monooxygenase - antagonists & inhibitors | Huntington Disease - pathology | Drosophila melanogaster - cytology | Tryptophan - chemistry | Kynurenine - chemistry | Kynurenic Acid - therapeutic use | Kynurenic Acid - metabolism | Animals, Genetically Modified - metabolism | Drosophila melanogaster - genetics | Kynurenine - analogs & derivatives | Tryptophan - metabolism | Nerve Degeneration - metabolism | Neuroprotective Agents - metabolism | Drosophila melanogaster - metabolism | Tryptophan Oxygenase - genetics | Animals | Tryptophan Oxygenase - chemistry | Kynurenine 3-Monooxygenase - chemistry | Kynurenine - metabolism | Kynurenic Acid - chemistry | Nerve Degeneration - drug therapy | Disease Models, Animal | Nervous system diseases | Metabolites | Huntington's chorea | Analysis | Drosophila | Tryptophan | Universities and colleges | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights