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Annals of Neurology, ISSN 0364-5134, 11/2012, Volume 72, Issue 5, pp. 766 - 778
Objective: Glioblastomas (GBMs) are lethal cancers that display cellular hierarchies parallel to normal brain. At the apex are GBM stem cells (GSCs), which are... 
SURVIVAL | HUMAN BRAIN-TUMORS | INTEGRINS | GLIOMA | ENDOTHELIAL-CELLS | NOTCH | VASCULAR NICHE | SELF-RENEWAL | NEUROSCIENCES | PERIVASCULAR NICHE | CLINICAL NEUROLOGY | TENASCIN-C | Neoplastic Stem Cells - drug effects | Tissue Array Analysis | Coculture Techniques | Humans | Brain Neoplasms - pathology | Glycoproteins - metabolism | Radiation | Male | Tumor Microenvironment - physiology | Antigens, CD - metabolism | Peptides - metabolism | Time Factors | Female | Brain Neoplasms - mortality | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | RNA Interference - physiology | Gene Expression Regulation, Neoplastic - physiology | Neoplastic Stem Cells - physiology | Neoplastic Stem Cells - radiation effects | Cell Survival - drug effects | Endothelial Cells - metabolism | RNA, Small Interfering - pharmacology | Computational Biology | Kaplan-Meier Estimate | Endothelial Cells - radiation effects | AC133 Antigen | Laminin - genetics | Magnetic Resonance Imaging | Regression Analysis | Analysis of Variance | Glioblastoma - pathology | Gene Expression Regulation, Neoplastic - radiation effects | Laminin - metabolism | Endothelial Cells - pathology | Dose-Response Relationship, Radiation | Glioblastoma - mortality | Endothelial Cells - drug effects | Studies | Cells | Tumors | Index Medicus
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 11/2014, Volume 34, Issue 46, pp. 15260 - 15280
Laminins are major constituents of the gliovascular basal lamina of the blood-brain barrier (BBB); however, the role of laminins in BBB development remains... 
blood-brain barrier | gliovascular | CONGENITAL MUSCULAR-DYSTROPHY | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | pericyte | MEROSIN | ALZHEIMERS-DISEASE | MOUSE | CELL-ADHESION | dystroglycan | NEUROSCIENCES | laminin | CENTRAL-NERVOUS-SYSTEM | MICE | astrocyte | BASEMENT-MEMBRANE
Journal Article
HUMAN MUTATION, ISSN 1059-7794, 10/2018, Volume 39, Issue 10, pp. 1314 - 1337
Congenital muscular dystrophy type 1A (MDC1A) is one of the main subtypes of early-onset muscle disease, caused by disease-associated variants in the... 
laminin-alpha 2 | locus-specific database | CONGENITAL MUSCULAR-DYSTROPHY | CORTICAL DYSPLASIA | PROTEIN | LAMA2 | ABNORMALITIES | LAMININ ALPHA-2-CHAIN | congenital | mutation update | muscular dystrophy | GENETICS & HEREDITY | PERIPHERAL NEUROPATHY | PARTIAL MEROSIN DEFICIENCY | EPILEPSY | ALPHA-2 CHAIN | BASEMENT-MEMBRANE
Journal Article
Human Mutation, ISSN 1059-7794, 10/2018, Volume 39, Issue 10, p. 1314
Congenital muscular dystrophy type 1A (MDC1A) is one of the main subtypes of early-onset muscle disease, caused by disease-associated variants in the... 
Genetic disorders | Laminin | Gene mutations | Analysis | Genes | Genetic aspects
Journal Article
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, ISSN 1357-2725, 07/2013, Volume 45, Issue 7, pp. 1204 - 1211
Integrins alpha(L)beta(2), alpha(M)beta(2) and alpha(X)beta(2) are expressed on leukocytes. Their primary ligands are counter transmembrane receptors or plasma... 
Complement receptors | CELLS | SITE | Cell trafficking | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUTROPHILS | I COLLAGEN | LAMININ RECEPTOR | Adhesion | VLA-2 | CELL BIOLOGY | Integrin | STRUCTURAL BASIS | Collagen | Extracellular matrix | A-DOMAIN | BINDING | ALPHA-2-BETA-1 INTEGRIN
Journal Article
HUMAN MOLECULAR GENETICS, ISSN 0964-6906, 02/2011, Volume 20, Issue 3, pp. 541 - 552
Journal Article
PLOS ONE, ISSN 1932-6203, 07/2010, Volume 5, Issue 7
Background: Laminin alpha 2 chain mutations cause congenital muscular dystrophy with dysmyelination neuropathy (MDC1A). Previously, we demonstrated that... 
INTEGRIN ALPHA-7-BETA-1 | DYSTROGLYCAN BINDING | SKELETAL-MUSCLE | CONGENITAL MUSCULAR-DYSTROPHY | SULFATIDE BINDING | LAMININ-ALPHA-1 CHAIN | REGENERATIVE CAPACITY | BIOLOGY | PERIPHERAL NEUROPATHY | SCHWANN-CELLS | BASEMENT-MEMBRANE
Journal Article
NEUROBIOLOGY OF AGING, ISSN 0197-4580, 02/2007, Volume 28, Issue 2, pp. 226 - 237
Pathological hallmarks of Alzheimer's disease are the presence of extracellular amyloid plaques, intracellular neurofibrillary tangles, and neurodegeneration.... 
PROTEIN | TYROSINE PHOSPHORYLATION | ALZHEIMERS-DISEASE | LAMININ | neurodegeneration | DEATH | FIBRILLOGENESIS | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | PEPTIDE | GERIATRICS & GERONTOLOGY | amyloid-beta | Pyk2 | alpha 2 beta 1 and alpha V beta 1 integrin | A-BETA | FOCAL ADHESION KINASE | Alzheimer's disease
Journal Article
PLOS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8
Congenital muscular dystrophy (CMD) is a clinically and genetically heterogeneous group of inherited muscle disorders. In patients, muscle weakness is usually... 
MUTANT | POPULATION | MEROSIN | MULTIDISCIPLINARY SCIENCES | LAMININ ALPHA-2 | PHENOTYPE | MICE | MODEL | LAMA2 GENE
Journal Article
Muscle & Nerve, ISSN 0148-639X, 01/2018, Volume 57, Issue 1, p. 54
Electrical impedance myography (EIM) is a noninvasive electrophysiological technique that characterizes muscle properties through bioimpedance. We compared EIM... 
Medicine, Experimental | Medical research | Laminin | Collagen | Muscular dystrophy | Correlation | Congenital diseases | Disorders | Muscles | Dystrophy | Impedance | Strength | Electrical impedance
Journal Article
Endocrinology, ISSN 0013-7227, 04/2017, Volume 158, Issue 4, pp. 963 - 978
Abstract A local axis connects the apical ectoplasmic specialization (ES) at the Sertoli-spermatid interface, the basal ES at the blood-testis barrier (BTB),... 
TOR protein | Regulators | AKT1 protein | Spatial discrimination | AKT protein | Rapamycin | Ribosomal protein S6 | Remodeling | Epithelium | Ribonucleic acid--RNA | Blood | Sertoli cells | Proteins | Signaling | Specialization | Laminin | Epidermal growth factor | Chain dynamics | Actin | Dynamics | Rodents | Regulation | Testes
Journal Article
TURKISH JOURNAL OF PEDIATRICS, ISSN 0041-4301, 05/2017, Volume 59, Issue 3, pp. 338 - 341
Laminin alpha 2 related congenital muscular dystrophy is one of the most common congenital muscular dystrophies of childhood with or without clinical evidence... 
congenital muscular dystrophy | dysgenesis | CONGENITAL MUSCULAR-DYSTROPHY | CORTICAL DYSPLASIA | laminin alpha 2 | PEDIATRICS | occipital cortex | EPILEPSY
Journal Article
MUSCLE & NERVE, ISSN 0148-639X, 07/2010, Volume 42, Issue 1, pp. 30 - 37
Several approaches to treat laminin alpha 2 chain-deficient congenital muscular dystrophy (MDC1A) in mouse models have been undertaken. Most have shown... 
CONGENITAL MUSCULAR-DYSTROPHY | MEROSIN | LAMININ-ALPHA-1 CHAIN | gene therapy | DYSTROGLYCAN | NEUROSCIENCES | heart | CLINICAL NEUROLOGY | SKELETAL-MUSCLE | muscular dystrophy | muscle | MOUSE MODEL | PERIPHERAL NEUROPATHY | laminin | GENE-TRANSFER | RESTRICTED DISTRIBUTION | EXPRESSION
Journal Article
AMERICAN JOURNAL OF PATHOLOGY, ISSN 0002-9440, 09/2005, Volume 167, Issue 3, pp. 823 - 833
Laminins are important for basement membrane structure and function. The laminin alpha 2 chain is a major component of muscle basement membranes, and mutations... 
CONGENITAL MUSCULAR-DYSTROPHY | MUTANT MICE | COLLAGEN-IV | MEROSIN | LAMININ GAMMA-3 CHAIN | PATHOLOGY | SERTOLI-CELLS | ALPHA-2 | EXPRESSION | MOUSE MODELS | BASEMENT-MEMBRANE
Journal Article
by Xiong, H and Tan, D and Wang, S and Song, S and Yang, H and Gao, K and Liu, A and Jiao, H and Mao, B and Ding, J and Chang, X and Wang, J and Wu, Y and Yuan, Y and Jiang, Y and Zhang, F and Wu, H and Wu, X
Clinical Genetics, ISSN 0009-9163, 03/2015, Volume 87, Issue 3, p. 233
  Laminin-[alpha]2 deficient congenital muscular dystrophy (CMD) is an autosomal recessive disorder characterized by severe muscular dystrophy, which is... 
Immunohistochemistry | Laminin | Gene mutations | Analysis | Epilepsy | Cytogenetics | Nucleotide sequencing | Muscular dystrophy | DNA sequencing | Genotype & phenotype | Mutation
Journal Article
Biomaterials, ISSN 0142-9612, 05/2013, Volume 34, Issue 16, p. 4027
Considerable effort has been directed towards replacing lost teeth using tissue-engineering methods such as titanium implants. A number of studies have tried... 
Laminin | Peptides | Developmental biology | Analysis | Collagen
Journal Article
FRONTIERS IN AGING NEUROSCIENCE, ISSN 1663-4365, 07/2014, Volume 6
microRNAs (miRNAs) are widespread regulators of gene expression, but little is known of their potential roles in congenital muscular dystrophy type 1A (MDC1A).... 
MDC1A | CONGENITAL MUSCULAR-DYSTROPHY | MOUSE | PROLIFERATION | NEUROSCIENCES | GERIATRICS & GERONTOLOGY | BIOMARKERS | muscular dystrophy | GENE | inflammation | TRANSFORMING GROWTH-FACTOR-BETA-1 | microRNA | fibrosis | laminin | MICE | MEROSIN DEFICIENCY | EXPRESSION
Journal Article
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