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Leukemia, ISSN 0887-6924, 08/2014, Volume 29, Issue 3, pp. 606 - 614
Using serum-containing culture, we examined whether AGM-S3 stromal cells, alone or in combination with hematopoietic growth factor(s), stimulated the... 
CHRONIC MYELOGENOUS LEUKEMIA | PATHOGENESIS | STEM-CELLS | ONCOLOGY | SCID MICE | RAS MUTATIONS | MOUSE | REPOPULATION | IMPROVEMENT | MODEL | THROMBOPOIETIN | HEMATOLOGY | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism | Embryonic Stem Cells - metabolism | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Antigens, CD34 - metabolism | Leukemia, Myelomonocytic, Juvenile - metabolism | Stromal Cells - pathology | Coculture Techniques | Humans | Hematopoietic Stem Cells - pathology | ras Proteins - metabolism | Neoplastic Stem Cells - metabolism | Stromal Cells - drug effects | Neoplastic Stem Cells - pathology | Clone Cells | Membrane Proteins - metabolism | Leukemia, Myelomonocytic, Juvenile - genetics | Hematopoietic Stem Cells - drug effects | Proto-Oncogene Proteins - metabolism | ADP-ribosyl Cyclase 1 - genetics | Signal Transduction | Leukemia, Myelomonocytic, Juvenile - pathology | Membrane Proteins - genetics | Stromal Cells - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Proto-Oncogene Proteins - genetics | Hematopoietic Stem Cells - metabolism | Gene Expression Regulation, Leukemic | Mice, SCID | Neoplastic Stem Cells - transplantation | Animals | GTP Phosphohydrolases - metabolism | Embryonic Stem Cells - drug effects | GTP Phosphohydrolases - genetics | Adolescent | Embryonic Stem Cells - pathology | ADP-ribosyl Cyclase 1 - metabolism | Mice, Inbred NOD | Cell Proliferation - drug effects | Mice | Mutation | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - genetics | Antigens, CD34 - genetics
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, p. e24397
Cancer stem cells (CSCs) possess high tumor-initiating capacity and have been reported to be resistant to therapeutics. Vice versa, therapy-resistant cancer... 
PROGENITOR CELLS | LIVER-CANCER | LUNG-CANCER | SIDE POPULATION | PROSPECTIVE IDENTIFICATION | MULTIDISCIPLINARY SCIENCES | PANCREATIC-CANCER | IN-VIVO | ALDEHYDE DEHYDROGENASE 1 | LEUKEMIC STEM-CELLS | SELF-RENEWAL | Neoplastic Stem Cells - cytology | Paclitaxel - pharmacology | Humans | Immunoblotting | Male | Antineoplastic Agents - therapeutic use | Retinoblastoma-Binding Protein 2 - metabolism | Retinoblastoma-Binding Protein 2 - genetics | Neoplastic Stem Cells - metabolism | Hyaluronan Receptors - metabolism | Antineoplastic Agents - pharmacology | Etoposide - pharmacology | Etoposide - therapeutic use | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Hyaluronan Receptors - genetics | Paclitaxel - therapeutic use | Animals | Epigenesis, Genetic - genetics | Staurosporine - therapeutic use | Fluorescent Antibody Technique | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Staurosporine - pharmacology | Cell proliferation | Drugs | Staurosporine | Lung cancer | Colorectal cancer | Bladder | Stem cell transplantation | Cytotoxicity | Metastasis | Drug resistance | Cancer therapies | Ovarian cancer | Colon cancer | Allografts | Restoration | Urinary bladder | CD44 antigen | Paclitaxel | Colon | Cytokines | Taxol | Etoposide | Breast cancer | Tumorigenicity | Regeneration | Chemotherapy | Stem cells | Epigenetics | Prostate cancer | Prostate | Cancer | Tumors
Journal Article
Developmental Cell, ISSN 1534-5807, 02/2018, Volume 44, Issue 3, pp. 362 - 377.e7
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 2016, Volume 22, Issue 12, pp. 2172 - 2179
Journal Article
Journal Article
Blood, ISSN 0006-4971, 01/2008, Volume 111, Issue 2, pp. 800 - 805
Mantle cell lymphoma (MCL) is defined pathologically by the detection of CD20, CD5, and most importantly cyclin D1 (CCND1). Its distinction from other... 
CD5 Antigens - genetics | Central Nervous System - metabolism | Oligonucleotide Array Sequence Analysis | Humans | Brain Neoplasms - pathology | Cyclins - genetics | Lymphoma, Mantle-Cell - pathology | Lymphopoiesis - genetics | Central Nervous System - pathology | Gene Expression Profiling | Central Nervous System - embryology | Brain Neoplasms - metabolism | Embryo, Mammalian - metabolism | Glioma - metabolism | Brain - metabolism | Glioma - genetics | Lymphoma, Mantle-Cell - diagnosis | Cell Nucleus - metabolism | Cyclins - metabolism | Cell Transformation, Neoplastic - genetics | Gene Expression Regulation, Developmental | Glioma - pathology | Trans-Activators - genetics | Trans-Activators - biosynthesis | B-Lymphocytes - pathology | Cyclin D | Neoplasm Proteins - genetics | Lymphoma, Mantle-Cell - genetics | Lymphoma, Mantle-Cell - metabolism | Embryo, Mammalian - pathology | Neoplasm Proteins - biosynthesis | Brain Neoplasms - genetics | Antigens, CD20 - metabolism | Gene Expression Regulation, Leukemic | CD5 Antigens - metabolism | Organ Specificity | Cell Transformation, Neoplastic - metabolism | Antigens, CD20 - genetics | Sequence Homology, Amino Acid | Cell Nucleus - genetics | Brain - pathology | High Mobility Group Proteins - biosynthesis | Biomarkers, Tumor - genetics | SOXC Transcription Factors | Cell Transformation, Neoplastic - pathology | Biomarkers, Tumor - biosynthesis | High Mobility Group Proteins - genetics | Clinical Medicine | Hematologi | Medical and Health Sciences | Hematology | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Journal Article
International Journal of Oncology, ISSN 1019-6439, 07/2016, Volume 49, Issue 1, pp. 74 - 88
Apoptotic defects are frequently associated with poor outcome in pediatric acute lymphoblastic leukaemia (ALL) hence there is an ongoing demand for novel... 
inhibitor of apoptosis protein | apoptosis | Akt | acute lympho blastic leukaemia | tumour necrosis factor-related apoptosis-inducing ligand | caspase | Caspase | Acute lymphoblastic leukaemia | Tumour necrosis factor-related apoptosis-inducing ligand | Apoptosis | Inhibitor of apoptosis protein | CANCER-CELLS | DEATH RECEPTORS | MICROTUBULE-TARGETING AGENT | COMBINATION | PACLITAXEL | FAMILY | INHIBITION | ONCOLOGY | PATHWAY | acute lymphoblastic leukaemia | C-FLIP | RESISTANCE | Oxazepines - administration & dosage | TNF-Related Apoptosis-Inducing Ligand - administration & dosage | Apoptosis - drug effects | Humans | Gene Expression Regulation, Leukemic - drug effects | Caspase 8 - biosynthesis | CASP8 and FADD-Like Apoptosis Regulating Protein - biosynthesis | Receptors, TNF-Related Apoptosis-Inducing Ligand - biosynthesis | Drug Synergism | Phosphatidylinositol 3-Kinases - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Drug Resistance, Neoplasm - genetics | Signal Transduction - drug effects | Pyrroles - administration & dosage | Myeloid Cell Leukemia Sequence 1 Protein - biosynthesis | Cell Line, Tumor | Receptors, TNF-Related Apoptosis-Inducing Ligand - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | TNF-Related Apoptosis-Inducing Ligand - genetics | Antimitotic agents | Patient outcomes | Development and progression | Genetic aspects | Acute lymphocytic leukemia | Genetic regulation | Antineoplastic agents | Health aspects | Pediatrics | Immunoglobulins | Ethanol | Leukemia | Glycerol | Kinases | Drug resistance | Studies | Cell growth | Lymphocytes | Medical prognosis | TNF inhibitors | Tumor necrosis factor-TNF | Ligands | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, p. e0126968
Background The transmembrane 9 superfamily protein member 4, TM9SF4, belongs to the TM9SF family of proteins highly conserved through evolution. TM9SF4... 
YEAST | CANNIBALISM | MULTIDISCIPLINARY SCIENCES | HEMATOPOIETIC STEM-CELLS | BONE-MARROW | NICHE | AUTOPHAGY | IDENTIFICATION | Oxygen - pharmacology | Apoptosis - drug effects | Humans | Leukemia, Myeloid, Acute - metabolism | Hematopoietic Stem Cells - pathology | Monocytes - metabolism | Neoplasm Proteins - metabolism | Cell Hypoxia | Granulocytes - drug effects | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Cloning, Molecular | HEK293 Cells | Monocytes - pathology | Bone Marrow Cells - drug effects | Granulocytes - pathology | Membrane Proteins - metabolism | Granulocytes - metabolism | Tumor Cells, Cultured | Neoplasm Proteins - genetics | Hematopoietic Stem Cells - drug effects | Promoter Regions, Genetic | Signal Transduction | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Leukemia, Myeloid, Acute - pathology | Membrane Proteins - genetics | Bone Marrow Cells - pathology | Hematopoietic Stem Cells - metabolism | Gene Expression Regulation, Leukemic | Cell Adhesion - drug effects | Fibronectins - metabolism | Monocytes - drug effects | Cell Differentiation - drug effects | Cell Proliferation - drug effects | Primary Cell Culture | Cell Cycle - drug effects | Bone Marrow Cells - metabolism | Leukemia, Myeloid, Acute - genetics | Fibronectins | Care and treatment | Patient outcomes | Melanoma | Development and progression | Research | Risk factors | Leukemia | Biological evolution | Homology | Oncology | Innate immunity | Cannibalism | Autophagy | Immunity | Myelodysplastic syndrome | Fibronectin | Cell adhesion & migration | Metastases | Cell adhesion molecules | Proteins | Cell adhesion | Bone marrow | Extracellular matrix | Physiology | CD34 antigen | Myeloid cells | Hematology | Myeloid leukemia | Mammals | Gene expression | Adhesion | Hemopoiesis | Medicine | Progeny | Bone cancer | Monocytes | Insects | MicroRNAs | Cells (biology) | Stem cells | Hypoxia | Differentiation | Acute myeloid leukemia | Phagocytosis | Cancer
Journal Article