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Journal Article
Thoracic cord compression due to ossified hypertrophied ligamentum flavum, 12/2002
Ossified ligamentum flavum is increasingly appreciated as an important cause of thoracic myeloradiculopathy. Fifteen patients with age ranging from 30-61 years... 
Ossified ligamentum flavum, Thoracic cord compression, Paraplegia
Journal
by Xie, L and Zhang, X and Xi, ZP and Li, JC
MEDICINE, ISSN 0025-7974, 05/2019, Volume 98, Issue 20, p. e15665
Journal Article
Journal Article
by Cao, YF and Li, H and Liu, WD and Yu, WJ and Gao, K
MEDICINE, ISSN 0025-7974, 10/2019, Volume 98, Issue 43, p. e17456
Introduction: Calcification of ligamentum flavum (CLF) is an important cause of spinal stenosis and spinal cord compression. CLF does not usually induce... 
ligamentum flavum | MEDICINE, GENERAL & INTERNAL | immediate quadriparesis | calcification | OSSIFICATION | cervical spine
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2017, Volume 12, Issue 6, p. e0178986
Thoracic ossification of the ligamentum flavum (TOLF) is characterized by ectopic bone formation in the ligamentum flavum and is considered to be a leading... 
CELLS | POPULATION | SPONDYLOARTHRITIS | OSTEOBLAST DIFFERENTIATION | SPINE | BONE-FORMATION | TRANSCRIPTION FACTOR OSTERIX | MULTIDISCIPLINARY SCIENCES | OSTEOGENIC DIFFERENTIATION | MYELOPATHY | CLINICAL-FEATURES | Cell Proliferation | Ossification, Heterotopic - pathology | Humans | Cells, Cultured | Osteoblasts - immunology | Proto-Oncogene Proteins c-myc - immunology | Ligamentum Flavum - cytology | Ossification, Heterotopic - immunology | MAP Kinase Signaling System | Thoracic Vertebrae - immunology | Osteoblasts - pathology | Cyclin D1 - immunology | S Phase | Tumor Necrosis Factor-alpha - immunology | Thoracic Vertebrae - pathology | Ligamentum Flavum - immunology | Ligamentum Flavum - pathology | Osteogenesis | Tumor necrosis factor | Growth | Bones | Inflammation | Genetic aspects | Research | Gene expression | Ossification | Cell culture | Transcription factors | Profiling | Pathogenesis | c-Myc protein | Assaying | Cyclin D1 | Proteins | Etiology | Surgery | Biocompatibility | Central nervous system diseases | MAP kinase | JNK protein | Thorax | Metabolism | Patients | Diseases | Polymerase chain reaction | Hospitals | Osteoblastogenesis | Inhibitors | Orthopedics | Cell proliferation | Flow cytometry | Spinal cord | Transcription | Laboratories | Genes | Stimulation | Arthritis | Activation | Myc protein | Biomedical materials | Cell cycle | Tumor necrosis factor-TNF | Bone morphogenetic protein 2 | Extracellular signal-regulated kinase | Ribonucleic acid--RNA | Flow | Cytometry | Fractures | Protein kinase | Proteomics | Bone | Differentiation | Ossification (ectopic) | RNA | Ribonucleic acid
Journal Article
Journal of Orthopaedic Research, ISSN 0736-0266, 12/2019, Volume 37, Issue 12, pp. 2634 - 2644
ABSTRACT Ligamentum flavum hypertrophy (LFH) is the most important component of lumbar spinal canal stenosis. Although the pathophysiology of LFH has been... 
CCN5 | ligamentum flavum | CRISPR | TGF‐β1 | myofibroblast
Journal Article
European Spine Journal, ISSN 0940-6719, 8/2017, Volume 26, Issue 8, pp. 2021 - 2030
Journal Article
Spine, ISSN 0362-2436, 05/2013, Volume 38, Issue 12, pp. E748 - E754
Journal Article
Spine, ISSN 0362-2436, 11/2009, Volume 34, Issue 24, pp. 2654 - 2661
Journal Article
World Neurosurgery, ISSN 1878-8750, 02/2018, Volume 110, pp. 284 - 287
Journal Article
Journal Article
The Spine Journal, ISSN 1529-9430, 04/2018, Volume 18, Issue 4, pp. 551 - 557
Thoracic ossification of the ligamentum flavum (TOLF) is an uncommon pathology, but it may sometimes grow and cause serious neurologic manifestations. Little... 
Prevalence | Computed tomography | Thoracic spine | Ligamentum flavum | Thoracic kyphosis | Ossification | POPULATION | YELLOW LIGAMENT | CLINICAL NEUROLOGY | SPINE | MYELOPATHY | ORTHOPEDICS | MORPHOLOGY | Medical records | CT imaging | Respiratory tract diseases | Epidemiology | Prevalence studies (Epidemiology)
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8, p. e0200872
Ligamentum flavum (LF) hypertrophy in lumbar spinal canal stenosis (LSCS) is characterized by a loss of elastic fibers and fibrosis. Chronic inflammation is... 
SPINAL-CANAL STENOSIS | PATHOGENESIS | FIBROSIS | HYPERTROPHY | ANGIOGENESIS | PATHWAY | MULTIDISCIPLINARY SCIENCES | PATHOMECHANISM | DERMAL FIBROBLASTS | INTERLEUKIN-6 | EXPRESSION | Constriction, Pathologic - congenital | Constriction, Pathologic - pathology | Fibroblasts - enzymology | Humans | Middle Aged | Male | RNA, Messenger - metabolism | Young Adult | Ligamentum Flavum - surgery | Lumbar Vertebrae - surgery | Matrix Metalloproteinase 9 - metabolism | Aged, 80 and over | Lumbar Vertebrae - abnormalities | Adult | Female | Interleukin-6 - administration & dosage | Interleukin-6 - metabolism | STAT3 Transcription Factor - metabolism | Signal Transduction | Matrix Metalloproteinase 2 - metabolism | Cells, Cultured | Gene Expression Regulation | Fibroblasts - pathology | Ligamentum Flavum - enzymology | Elastic Tissue - pathology | Constriction, Pathologic - surgery | Fibroblasts - drug effects | Aged | Lumbar Vertebrae - pathology | Constriction, Pathologic - enzymology | STAT3 Transcription Factor - antagonists & inhibitors | Elastic Tissue - enzymology | Ligamentum Flavum - pathology | Lumbar Vertebrae - enzymology | Care and treatment | Inflammation | Research | Interleukins | Correlation | Nuclear magnetic resonance--NMR | Transcription | Disease | Interleukin | Stenosis | Matrix metalloproteinase | Kinases | Males | Bone surgery | Fibers | Stains & staining | Degradation | Interleukin 6 | Proteins | Angiogenesis | Signal transduction | Surgery | Fibroblasts | Life sciences | Degeneration | Metalloproteinase | Growth factors | Cytokines | Secretion | Elastin | Stat3 protein | Gene expression | Patients | Gelatinase B | Gelatinase A | Signaling | Orthopedics | Collagen | Fibrosis | Hypertrophy | Nuclear magnetic resonance | NMR
Journal Article
Asian Spine Journal, ISSN 1976-1902, 02/2014, Volume 8, Issue 1, pp. 89 - 96
Ossification of the ligamentum flavum is a rare cause of thoracic myelopathy. It develops in East Asians more frequently than in people from other areas. The... 
Ossification of ligamentum flavum | Prognostic factors | Treatment | Review
Journal Article