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Molecular Pharmacology, ISSN 0026-895X, 09/2011, Volume 80, Issue 3, pp. 367 - 377
Journal Article
Trends in Pharmacological Sciences, ISSN 0165-6147, 12/2017, Volume 38, Issue 12, pp. 1110 - 1124
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 03/2013, Volume 12, Issue 3, pp. 205 - 216
Agonists of seven-transmembrane receptors, also known as G protein-coupled receptors (GPCRs), do not uniformly activate all cellular signalling pathways linked... 
Algorithms | Animals | Signal Transduction - drug effects | Humans | Drug Therapy | Ligands | Signal Transduction - physiology | Receptors, G-Protein-Coupled - drug effects | Drug Discovery | Receptors, G-Protein-Coupled - physiology | Drugs | Physiological aspects | Cellular signal transduction | Genetic aspects | Product/Service Evaluations | Research | Methods
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2013, Volume 169, Issue 7, pp. 1430 - 1446
In order to describe drug action at a GPCR, a full understanding of the pharmacological terms affinity, efficacy and potency is necessary. This is true whether... 
intrinsic efficacy | GPCR | μ‐opioid receptor | ligand bias | efficacy | μ-opioid receptor | Animals | Morphine - pharmacology | Enkephalin, Ala-MePhe-Gly- - pharmacology | Receptors, Opioid, mu - metabolism | Humans | Analgesics, Opioid - pharmacology | Receptors, Opioid, mu - agonists | Reviews
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 08/2013, Volume 169, Issue 7, pp. 1430 - 1446
In order to describe drug action at a GPCR, a full understanding of the pharmacological terms affinity, efficacy and potency is necessary. This is true whether... 
AGONIST EFFICACY | MULTISITE PHOSPHORYLATION | PROTEIN-COUPLED RECEPTORS | efficacy | QUANTITATIVE PHARMACOLOGY | OPIATE-RECEPTOR | 7-TRANSMEMBRANE RECEPTORS | ligand bias | RAT VAS-DEFERENS | intrinsic efficacy | mu-opioid receptor | GPCR | FUNCTIONAL SELECTIVITY | PHARMACOLOGY & PHARMACY | LOCUS-COERULEUS NEURONS | BETA-ADRENERGIC RECEPTOR
Journal Article
Expert Opinion on Drug Discovery, ISSN 1746-0441, 04/2017, Volume 12, Issue 4, pp. 321 - 333
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 01/2018, Volume 83, Issue 2, pp. 733 - 739
We report here the first corannulene-based molecular cage, constructed via metal-induced self-assembly of corannulene-based ligands. In sharp contrast to those... 
AROMATIC-HYDROCARBONS | AMPLIFICATION | RECOGNITION | DISCRETE | STRATEGY | ENCAPSULATION | CHEMISTRY, ORGANIC | BOWL INVERSION | CHIRALITY | EXCHANGE | DERIVATIVES | Ligands | Chemical properties | Research | Enantiomers | Equilibrium (Physics)
Journal Article
ACS Nano, ISSN 1936-0851, 05/2018, Volume 12, Issue 5, pp. 4218 - 4223
Opioid neuropeptides play a significant role in pain perception, appetite regulation, sleep, memory, and learning. Advances in understanding of opioid peptide... 
bias-free | microelectrode | neuropeptides | biosensors | kinetics | graphene | affinity | MATERIALS SCIENCE, MULTIDISCIPLINARY | SCALABLE PRODUCTION | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | ADSORPTION | CHEMISTRY, MULTIDISCIPLINARY | MU-OPIOID RECEPTOR | IMMOBILIZATION | ENKEPHALIN | DYSREGULATION | SURFACE | LIGAND | BINDING
Journal Article